JP2025172140A5 - - Google Patents

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Publication number
JP2025172140A5
JP2025172140A5 JP2025145434A JP2025145434A JP2025172140A5 JP 2025172140 A5 JP2025172140 A5 JP 2025172140A5 JP 2025145434 A JP2025145434 A JP 2025145434A JP 2025145434 A JP2025145434 A JP 2025145434A JP 2025172140 A5 JP2025172140 A5 JP 2025172140A5
Authority
JP
Japan
Prior art keywords
amino acid
composition according
peptide
terminus
modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025145434A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025172140A (ja
Filing date
Publication date
Priority claimed from PCT/US2019/056955 external-priority patent/WO2020086400A1/en
Application filed filed Critical
Publication of JP2025172140A publication Critical patent/JP2025172140A/ja
Publication of JP2025172140A5 publication Critical patent/JP2025172140A5/ja
Pending legal-status Critical Current

Links

JP2025145434A 2018-10-22 2025-09-02 Cxcr3の切断可能な活性化因子および使用方法 Pending JP2025172140A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862748711P 2018-10-22 2018-10-22
US62/748,711 2018-10-22
PCT/US2019/056955 WO2020086400A1 (en) 2018-10-22 2019-10-18 Cleavable activators of cxcr3 and methods of use
JP2021521472A JP7426121B2 (ja) 2018-10-22 2019-10-18 Cxcr3の切断可能な活性化因子および使用方法
JP2023198254A JP7798368B2 (ja) 2018-10-22 2023-11-22 Cxcr3の切断可能な活性化因子および使用方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2023198254A Division JP7798368B2 (ja) 2018-10-22 2023-11-22 Cxcr3の切断可能な活性化因子および使用方法

Publications (2)

Publication Number Publication Date
JP2025172140A JP2025172140A (ja) 2025-11-20
JP2025172140A5 true JP2025172140A5 (enExample) 2026-03-30

Family

ID=70330587

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2021521472A Active JP7426121B2 (ja) 2018-10-22 2019-10-18 Cxcr3の切断可能な活性化因子および使用方法
JP2023198254A Active JP7798368B2 (ja) 2018-10-22 2023-11-22 Cxcr3の切断可能な活性化因子および使用方法
JP2025145434A Pending JP2025172140A (ja) 2018-10-22 2025-09-02 Cxcr3の切断可能な活性化因子および使用方法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2021521472A Active JP7426121B2 (ja) 2018-10-22 2019-10-18 Cxcr3の切断可能な活性化因子および使用方法
JP2023198254A Active JP7798368B2 (ja) 2018-10-22 2023-11-22 Cxcr3の切断可能な活性化因子および使用方法

Country Status (12)

Country Link
US (2) US12110316B2 (enExample)
EP (1) EP3870212A4 (enExample)
JP (3) JP7426121B2 (enExample)
KR (1) KR20210081372A (enExample)
CN (2) CN120022352A (enExample)
AU (2) AU2019365654B2 (enExample)
BR (1) BR112021007414A2 (enExample)
CA (1) CA3116325A1 (enExample)
IL (2) IL324815A (enExample)
MX (1) MX2021004496A (enExample)
SG (1) SG11202103497WA (enExample)
WO (1) WO2020086400A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210081372A (ko) * 2018-10-22 2021-07-01 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 절단 가능한 cxcr3의 활성제 및 이의 사용 방법
GB202208950D0 (en) * 2022-06-17 2022-08-10 Ucl Business Ltd Treatment of the corneal endothelium
WO2024118744A2 (en) * 2022-11-30 2024-06-06 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Coacervate formulations of cxcr3-activating peptides for controlled release in ophthalmic and topical treatments

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994292A (en) * 1995-05-31 1999-11-30 The United States Of America As Represented By The Department Of Health And Human Services Interferon-inducible protein 10 is a potent inhibitor of angiogenesis
MXPA00003885A (es) 1997-10-22 2004-04-23 Inst Genetics Llc Quimiocinas con modificiaciones de la terminacion amino.
US20070116669A1 (en) * 2002-09-13 2007-05-24 Chemokine Therapeutics Corporation Interferon-inducible protein-10 (IP-10 or CXCL10) chemokine analogs for the treatment of human diseases
GB2377444A (en) 2001-04-09 2003-01-15 Smithkline Beecham Plc Chemokine-family polypeptide
IL164942A0 (en) * 2004-10-31 2005-12-18 Yeda Res & Dev The use of a protease or a protease inhibitor for the manufacture of medicaments
US9180167B2 (en) 2011-08-26 2015-11-10 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Activators of CXCR3 for the treatment of angiopathies of the eye
US8734775B2 (en) 2011-08-26 2014-05-27 University Of Pittsburgh Chemokine derived peptides that bind with chemokine receptor CXCR3 and uses for chronic wound and angiogenesis inhibition treatments
AU2014306074B2 (en) * 2013-08-05 2018-08-30 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
US9895419B2 (en) * 2014-01-21 2018-02-20 University of Pittsburgh—of the Commonwealth System of Higher Education Goblet cell replacement therapy
ES2738582T3 (es) * 2014-02-14 2020-01-23 Immune Design Corp Inmunoterapia del cáncer a través de combinación de inmunoestimulación local y sistémica
AU2017290828A1 (en) * 2016-06-30 2019-01-24 Virogin Biotech Canada Ltd Pseudotyped oncolytic viral delivery of therapeutic polypeptides
JP7626577B2 (ja) 2016-11-28 2025-02-07 中外製薬株式会社 リガンド結合活性が調整可能なリガンド結合分子
SG11201909160WA (en) * 2017-04-11 2019-10-30 Inhibrx Inc Multispecific polypeptide constructs having constrained cd3 binding and methods of using the same
KR20210081372A (ko) 2018-10-22 2021-07-01 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 절단 가능한 cxcr3의 활성제 및 이의 사용 방법

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