JP2025081512A5 - - Google Patents

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Publication number
JP2025081512A5
JP2025081512A5 JP2025024834A JP2025024834A JP2025081512A5 JP 2025081512 A5 JP2025081512 A5 JP 2025081512A5 JP 2025024834 A JP2025024834 A JP 2025024834A JP 2025024834 A JP2025024834 A JP 2025024834A JP 2025081512 A5 JP2025081512 A5 JP 2025081512A5
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JP
Japan
Prior art keywords
seq
cancer
cdr
domain
set forth
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025024834A
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English (en)
Japanese (ja)
Other versions
JP2025081512A (ja
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Publication date
Priority claimed from JP2021557377A external-priority patent/JP2022527081A/ja
Application filed filed Critical
Publication of JP2025081512A publication Critical patent/JP2025081512A/ja
Publication of JP2025081512A5 publication Critical patent/JP2025081512A5/ja
Pending legal-status Critical Current

Links

JP2025024834A 2019-03-26 2025-02-19 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t) Pending JP2025081512A (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201962824080P 2019-03-26 2019-03-26
US62/824,080 2019-03-26
US201962931103P 2019-11-05 2019-11-05
US62/931,103 2019-11-05
US202062969569P 2020-02-03 2020-02-03
US62/969,569 2020-02-03
JP2021557377A JP2022527081A (ja) 2019-03-26 2020-03-26 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)
PCT/US2020/025069 WO2020198531A2 (en) 2019-03-26 2020-03-26 Chimeric antigen receptor modified t-cells (car-t) for the treatment of hematological and solid tumor cancers

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021557377A Division JP2022527081A (ja) 2019-03-26 2020-03-26 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)

Publications (2)

Publication Number Publication Date
JP2025081512A JP2025081512A (ja) 2025-05-27
JP2025081512A5 true JP2025081512A5 (enExample) 2025-07-31

Family

ID=72610137

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021557377A Pending JP2022527081A (ja) 2019-03-26 2020-03-26 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)
JP2025024834A Pending JP2025081512A (ja) 2019-03-26 2025-02-19 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021557377A Pending JP2022527081A (ja) 2019-03-26 2020-03-26 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)

Country Status (11)

Country Link
US (1) US20230312708A1 (enExample)
EP (1) EP3953372A4 (enExample)
JP (2) JP2022527081A (enExample)
KR (1) KR20210143804A (enExample)
CN (1) CN113710688A (enExample)
AU (1) AU2020248448B2 (enExample)
CA (1) CA3134465A1 (enExample)
IL (1) IL286618A (enExample)
MX (1) MX2021011494A (enExample)
SG (1) SG11202110131SA (enExample)
WO (1) WO2020198531A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116940378A (zh) * 2021-02-01 2023-10-24 加利福尼亚大学董事会 神经内分泌癌的治疗
CA3172530A1 (en) 2021-02-25 2022-09-01 Spencer PARK Ror1 targeting chimeric antigen receptor
KR20250044188A (ko) 2022-05-12 2025-03-31 하이난 심시어 자이밍 파마슈티컬 컴퍼니 리미티드 캄프토테신계 유도체 및 리간드-약물 접합체
US20240092941A1 (en) * 2022-07-11 2024-03-21 Fred Hutchinson Cancer Center Single-domain antibodies that bind ror1
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
WO2025076127A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025079987A2 (ko) * 2023-10-10 2025-04-17 서울대학교산학협력단 키메라 항원 수용체를 발현하는 자연 살해 세포를 이용한 종양 미세환경의 주피세포를 표적하는 항암 세포 치료 기법 및 치료 효능 평가를 위한 종양 미세환경 오가노이드 모델 제작 기술
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130266551A1 (en) * 2003-11-05 2013-10-10 St. Jude Children's Research Hospital, Inc. Chimeric receptors with 4-1bb stimulatory signaling domain
US9758591B2 (en) * 2012-08-24 2017-09-12 The Regents Of The University Of California Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis
KR102048855B1 (ko) * 2014-07-29 2019-11-26 셀렉티스 암 면역요법을 위한 ror1(ntrkr1) 특이적 키메라 항원 수용체
US20170333480A1 (en) * 2014-11-05 2017-11-23 Board Of Regents, The University Of Texas System Gene modified immune effector cells and engineered cells for expansion of immune effector cells
AU2016206457B2 (en) * 2015-01-16 2021-11-11 Juno Therapeutics, Inc. Antibodies and chimeric antigen receptors specific for ROR1
KR20180111870A (ko) * 2016-02-25 2018-10-11 셀 메디카 스위처란트 아게 Pd-l1에 대한 결합 성분
MY200337A (en) * 2016-10-07 2023-12-20 Novartis Ag Nucleic acid molecules encoding chimeric antigen receptors comprising a cd20 binding domain
CN108424458A (zh) * 2017-02-13 2018-08-21 上海恒润达生生物科技有限公司 靶向ny-eso-1的嵌合抗原受体及其用途
AU2018289581C1 (en) * 2017-06-23 2025-01-30 VelosBio Inc. ROR1 antibody immunoconjugates
CN116018353A (zh) * 2019-11-18 2023-04-25 加利福尼亚大学董事会 抗ror-2抗体和使用方法

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