JP2025010148A5 - - Google Patents

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Publication number
JP2025010148A5
JP2025010148A5 JP2024170988A JP2024170988A JP2025010148A5 JP 2025010148 A5 JP2025010148 A5 JP 2025010148A5 JP 2024170988 A JP2024170988 A JP 2024170988A JP 2024170988 A JP2024170988 A JP 2024170988A JP 2025010148 A5 JP2025010148 A5 JP 2025010148A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024170988A
Other languages
Japanese (ja)
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JP2025010148A (ja
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Publication date
Priority claimed from JP2021517022A external-priority patent/JP2022502044A/ja
Application filed filed Critical
Publication of JP2025010148A publication Critical patent/JP2025010148A/ja
Publication of JP2025010148A5 publication Critical patent/JP2025010148A5/ja
Pending legal-status Critical Current

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JP2024170988A 2018-09-26 2024-09-30 タンパク質発現の増加および/またはハプロ不全障害の治療のための方法および組成物 Pending JP2025010148A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862736847P 2018-09-26 2018-09-26
US62/736,847 2018-09-26
JP2021517022A JP2022502044A (ja) 2018-09-26 2019-09-26 タンパク質発現の増加および/またはハプロ不全障害の治療のための方法および組成物
PCT/US2019/053268 WO2020069199A1 (en) 2018-09-26 2019-09-26 Methods and compositions for increasing protein expression and/or treating a haploinsufficiency disorder

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021517022A Division JP2022502044A (ja) 2018-09-26 2019-09-26 タンパク質発現の増加および/またはハプロ不全障害の治療のための方法および組成物

Publications (2)

Publication Number Publication Date
JP2025010148A JP2025010148A (ja) 2025-01-20
JP2025010148A5 true JP2025010148A5 (enExample) 2025-04-24

Family

ID=69949913

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021517022A Pending JP2022502044A (ja) 2018-09-26 2019-09-26 タンパク質発現の増加および/またはハプロ不全障害の治療のための方法および組成物
JP2024170988A Pending JP2025010148A (ja) 2018-09-26 2024-09-30 タンパク質発現の増加および/またはハプロ不全障害の治療のための方法および組成物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021517022A Pending JP2022502044A (ja) 2018-09-26 2019-09-26 タンパク質発現の増加および/またはハプロ不全障害の治療のための方法および組成物

Country Status (15)

Country Link
US (1) US12281314B2 (enExample)
EP (1) EP3856905A4 (enExample)
JP (2) JP2022502044A (enExample)
KR (1) KR102814622B1 (enExample)
CN (1) CN113195719A (enExample)
AU (1) AU2019350871A1 (enExample)
BR (1) BR112021005788A2 (enExample)
CA (1) CA3114109A1 (enExample)
CL (1) CL2021000747A1 (enExample)
CO (1) CO2021005040A2 (enExample)
EA (1) EA202190736A1 (enExample)
IL (1) IL281848A (enExample)
MX (1) MX2021003567A (enExample)
WO (1) WO2020069199A1 (enExample)
ZA (1) ZA202102302B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220128611A (ko) * 2019-11-04 2022-09-21 플래그쉽 파이어니어링, 인크. 맥락적 희귀 코돈용 trem 조성물 및 관련 용도
MX2022015042A (es) * 2020-05-29 2023-03-09 Flagship Pioneering Innovations Vi Llc Composiciones de trem y métodos relacionados con las mismas.
CA3182026A1 (en) * 2020-05-29 2021-12-02 Flagship Pioneering Innovations Vi, Llc. Trem compositions and methods relating thereto
CA3217460A1 (en) * 2021-05-05 2022-11-10 Peter M. EIMON Methods and compositions for treating a premature termination codon-mediated disorder
WO2023205606A1 (en) 2022-04-18 2023-10-26 Vertex Pharmaceuticals Incorporated Compositions and methods for enhancing aav therapy and decreasing tropism of aav to the liver
CN117257958B (zh) * 2023-11-21 2024-02-09 四川大学华西医院 Trps1抑制剂的新用途及用于治疗和/或预防雄激素性秃发的药物
WO2025176166A1 (en) * 2024-02-21 2025-08-28 Zhuhai Codone Biotechnology Co., Ltd. Engineered trna expression cassette

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000015775A1 (en) * 1998-09-17 2000-03-23 Smithkline Beecham Corporation Rnase p polypeptides
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
JP4406731B2 (ja) 2005-03-31 2010-02-03 国立大学法人 岡山大学 部位特異的アミノ酸導入法のための新規な直交化tRNA
WO2008127900A1 (en) 2007-04-13 2008-10-23 The Salk Institute For Biological Studies Methods of genetically encoding unnatural amino acids in eukaryotic cells using orthogonal trna/synthetase pairs
US20120283116A1 (en) * 2009-09-11 2012-11-08 Leppert Mark F Mutant Sodium Channel Nav1.7 and Methods Related Thereto
US9676810B2 (en) 2010-07-08 2017-06-13 The Brigham And Women's Hospital, Inc. Neuroprotective molecules and methods of treating neurological disorders and inducing stress granules
US20130129668A1 (en) 2011-09-01 2013-05-23 The Regents Of The University Of California Diagnosis and treatment of arthritis using epigenetics
WO2014052855A1 (en) * 2012-09-27 2014-04-03 Population Diagnostics, Inc. Methods and compositions for screening and treating developmental disorders
EP3052624A1 (en) * 2013-10-02 2016-08-10 Wageningen Universiteit Systematic optimization of coding sequence for functional protein expression
EP3362087A1 (en) * 2015-10-15 2018-08-22 The Scripps Research Institute BINDING ACTIVITY OF AMINOACYL-tRNA SYNTHETASE IN CHARCOT-MARIE-TOOTH (CMT) NEUROPATHY AND CMT-RELATED NEUROLOGICAL DISEASES
US11083745B2 (en) * 2015-12-14 2021-08-10 Cold Spring Harbor Laboratory Antisense oligomers for treatment of autosomal dominant mental retardation-5 and Dravet Syndrome
WO2017193051A1 (en) * 2016-05-06 2017-11-09 The Trustees Of Princeton University Methods of monitoring rnase l activity
DK3458074T3 (da) * 2016-05-16 2024-07-29 Univ Texas COMPOSITIONS FOR THE DELIVERY OF tRNA AS NANOPARTICLES AND METHODS OF USE THEREWITH
US11848074B2 (en) * 2016-12-07 2023-12-19 Gottfried Wilhelm Leibniz Universität Hannover Codon optimization
EP3976782A1 (en) * 2019-05-31 2022-04-06 Flagship Pioneering, Inc. Uses of trem compositions to modulate trna pools

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