JP2024545145A - Ｃ末端ａ－アミド化への光化学的アプローチ - Google Patents

Ｃ末端ａ－アミド化への光化学的アプローチ Download PDF

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Publication number
JP2024545145A
JP2024545145A JP2024534351A JP2024534351A JP2024545145A JP 2024545145 A JP2024545145 A JP 2024545145A JP 2024534351 A JP2024534351 A JP 2024534351A JP 2024534351 A JP2024534351 A JP 2024534351A JP 2024545145 A JP2024545145 A JP 2024545145A
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Prior art keywords
peptide
terminal
formula
reaction
photochemical
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JP2024534351A
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Japanese (ja)
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JP2024545145A5 (https=
Inventor
マイケル・リチャード・ハリス
シドニー・ウォン
デヴィッド・トーマス・ヒメル
ヴォウター・フレデリク・ヨハン・ホーゲンドルフ
フェリックス・ヴォイチク
ニコラス・レイモンド・コックス
ベンジャミン・マシュー・ウィリアムズ
アスムス・リングルビョーグ・モートゥンスン
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Novo Nordisk AS
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Novo Nordisk AS
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Publication of JP2024545145A publication Critical patent/JP2024545145A/ja
Publication of JP2024545145A5 publication Critical patent/JP2024545145A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/003—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by transforming the C-terminal amino acid to amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2024534351A 2021-12-10 2022-12-09 Ｃ末端ａ－アミド化への光化学的アプローチ Pending JP2024545145A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163288071P 2021-12-10 2021-12-10
US63/288,071 2021-12-10
EP22152378.0 2022-01-20
EP22152378 2022-01-20
PCT/EP2022/085255 WO2023105074A1 (en) 2021-12-10 2022-12-09 Photochemical approach to c-terminal a-amidation

Publications (2)

Publication Number Publication Date
JP2024545145A true JP2024545145A (ja) 2024-12-05
JP2024545145A5 JP2024545145A5 (https=) 2025-12-25

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ID=84829963

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JP2024534351A Pending JP2024545145A (ja) 2021-12-10 2022-12-09 Ｃ末端ａ－アミド化への光化学的アプローチ

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US (1) US20250042935A1 (https=)
EP (1) EP4444735A1 (https=)
JP (1) JP2024545145A (https=)
WO (1) WO2023105074A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026009000A1 (en) 2024-07-04 2026-01-08 Solasta Bio Limited Methods for production of insecticidal neuropeptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580751A (en) 1990-09-14 1996-12-03 Carlsberg A/S Process for the preparation of C-terminally amidated peptides

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Publication number Publication date
EP4444735A1 (en) 2024-10-16
WO2023105074A1 (en) 2023-06-15
US20250042935A1 (en) 2025-02-06

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