JP2024542779A - 血管内ステント用の生体模倣コーティング - Google Patents

血管内ステント用の生体模倣コーティング Download PDF

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Publication number
JP2024542779A
JP2024542779A JP2024532976A JP2024532976A JP2024542779A JP 2024542779 A JP2024542779 A JP 2024542779A JP 2024532976 A JP2024532976 A JP 2024532976A JP 2024532976 A JP2024532976 A JP 2024532976A JP 2024542779 A JP2024542779 A JP 2024542779A
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JP
Japan
Prior art keywords
peptide
cell
trans
homophilic
stent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024532976A
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English (en)
Japanese (ja)
Other versions
JP2024542779A5 (enExample
Inventor
ジュゼッピーナ、カリジューリ
アントニオ、ニコレッティ
シャルル、スカーベック
エリザベッタ、ビアンキ
ラッファエーレ、インジェニート
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Universite Sorbonne Paris Nord
Universite Paris Cite
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Universite Sorbonne Paris Nord
Universite Paris Cite
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM, Universite Sorbonne Paris Nord, Universite Paris Cite filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Publication of JP2024542779A publication Critical patent/JP2024542779A/ja
Publication of JP2024542779A5 publication Critical patent/JP2024542779A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Prostheses (AREA)
JP2024532976A 2021-12-03 2022-12-02 血管内ステント用の生体模倣コーティング Pending JP2024542779A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IBPCT/IB2021/000860 2021-12-03
PCT/IB2021/000860 WO2023099932A1 (en) 2021-12-03 2021-12-03 Cd31 mimetic coating for endovascular stent
PCT/EP2022/084241 WO2023099748A2 (en) 2021-12-03 2022-12-02 Biomimetic coating for endovascular stent

Publications (2)

Publication Number Publication Date
JP2024542779A true JP2024542779A (ja) 2024-11-15
JP2024542779A5 JP2024542779A5 (enExample) 2025-12-02

Family

ID=79601491

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2024532976A Pending JP2024542779A (ja) 2021-12-03 2022-12-02 血管内ステント用の生体模倣コーティング
JP2024532974A Pending JP2024542778A (ja) 2021-12-03 2022-12-02 血管内ステント用の生体模倣コーティング

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024532974A Pending JP2024542778A (ja) 2021-12-03 2022-12-02 血管内ステント用の生体模倣コーティング

Country Status (10)

Country Link
US (2) US20250281679A1 (enExample)
EP (2) EP4440643A2 (enExample)
JP (2) JP2024542779A (enExample)
KR (2) KR20240155852A (enExample)
CN (2) CN118843485A (enExample)
AU (1) AU2022402537A1 (enExample)
CA (1) CA3241253A1 (enExample)
IL (1) IL313268A (enExample)
MX (1) MX2024006730A (enExample)
WO (3) WO2023099932A1 (enExample)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2294321A (en) * 1994-10-19 1996-04-24 Yamanouchi Research Inst Method of screening for CD31 interaction inhibitors
JP2011526485A (ja) * 2008-06-30 2011-10-13 アンスティテュ、ナショナル、ド、ラ、サント、エ、ド、ラ、ルシェルシュ、メディカル（アンセルム） 血栓障害および自己免疫障害の処置におけるｃｄ３１ペプチドの使用
SI2861241T1 (sl) * 2012-06-19 2021-11-30 Institut National De La Sante Et De La Recherche Medicale (Inserm) Izboljšani CD31 peptidi
CA3059800A1 (en) 2017-04-13 2018-10-18 Orbusneich Medical Pte. Ltd. Medical devices coated with polydopamine and antibodies
US20220001083A1 (en) 2018-11-27 2022-01-06 Balt Extrusion Method for the modification of a device surface by grafting a cd31-derived peptide onto the surface of said device
WO2020109833A1 (en) * 2018-11-27 2020-06-04 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method for the modification of a substrate surface by grafting a peptide onto the surface of said substrate
EP4157282A1 (en) 2020-05-28 2023-04-05 Institut National de la Santé et de la Recherche Médicale (INSERM) Compounds for the prevention, treatment and diagnosis of thrombi

Also Published As

Publication number Publication date
CA3241253A1 (en) 2023-06-08
WO2023099748A2 (en) 2023-06-08
WO2023099932A1 (en) 2023-06-08
US20250381324A1 (en) 2025-12-18
KR20240155852A (ko) 2024-10-29
WO2023099957A3 (en) 2023-07-13
EP4440643A2 (en) 2024-10-09
CN118475376A (zh) 2024-08-09
WO2023099748A3 (en) 2023-07-13
CN118843485A (zh) 2024-10-25
IL313268A (en) 2024-08-01
WO2023099957A2 (en) 2023-06-08
EP4440644A2 (en) 2024-10-09
KR20240155186A (ko) 2024-10-28
MX2024006730A (es) 2024-11-08
JP2024542778A (ja) 2024-11-15
US20250281679A1 (en) 2025-09-11
AU2022402537A1 (en) 2024-07-11

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