JP2024540863A5 - - Google Patents

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Publication number
JP2024540863A5
JP2024540863A5 JP2024522065A JP2024522065A JP2024540863A5 JP 2024540863 A5 JP2024540863 A5 JP 2024540863A5 JP 2024522065 A JP2024522065 A JP 2024522065A JP 2024522065 A JP2024522065 A JP 2024522065A JP 2024540863 A5 JP2024540863 A5 JP 2024540863A5
Authority
JP
Japan
Prior art keywords
amino acid
seq
acid sequence
taa
multispecific antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024522065A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540863A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/124961 external-priority patent/WO2023061417A1/en
Publication of JP2024540863A publication Critical patent/JP2024540863A/ja
Publication of JP2024540863A5 publication Critical patent/JP2024540863A5/ja
Pending legal-status Critical Current

Links

JP2024522065A 2021-10-12 2022-10-12 改善された治療指数を有するcd3標的化t細胞エンゲージャー Pending JP2024540863A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN2021123374 2021-10-12
CNPCT/CN2021/123374 2021-10-12
CN2022104995 2022-07-11
CNPCT/CN2022/104995 2022-07-11
PCT/CN2022/124961 WO2023061417A1 (en) 2021-10-12 2022-10-12 Cd3-targeting t-cell engagers with improved therapeutic index

Publications (2)

Publication Number Publication Date
JP2024540863A JP2024540863A (ja) 2024-11-06
JP2024540863A5 true JP2024540863A5 (https=) 2025-10-22

Family

ID=85987305

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024522065A Pending JP2024540863A (ja) 2021-10-12 2022-10-12 改善された治療指数を有するcd3標的化t細胞エンゲージャー

Country Status (5)

Country Link
US (1) US20240417469A1 (https=)
EP (1) EP4415825A4 (https=)
JP (1) JP2024540863A (https=)
CN (1) CN118556083A (https=)
WO (1) WO2023061417A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202532431A (zh) * 2023-09-21 2025-08-16 大陸商樂普創一生物科技(上海)有限公司 多特異性抗體及其用途
WO2025103425A1 (en) * 2023-11-15 2025-05-22 Concept To Medicine Biotech Co., Ltd. Multispecific antibodies and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201909160WA (en) * 2017-04-11 2019-10-30 Inhibrx Inc Multispecific polypeptide constructs having constrained cd3 binding and methods of using the same
KR20260046525A (ko) * 2018-04-11 2026-04-07 인히브릭스 바이오사이언스, 인크. 제한된 cd3 결합을 갖는 다중특이적 폴리펩티드 컨스트럭트 및 관련된 방법 및 용도
EP3827019A1 (en) * 2018-07-24 2021-06-02 Inhibrx, Inc. Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same
US12509524B2 (en) * 2018-09-28 2025-12-30 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule comprising altered antibody variable region
CN113166261A (zh) * 2018-10-11 2021-07-23 印希比股份有限公司 B7h3单域抗体及其治疗性组合物
JP2022504802A (ja) * 2018-10-11 2022-01-13 インヒブルクス インコーポレイテッド 5t4シングルドメイン抗体およびその治療組成物
CN110669137B (zh) * 2019-10-24 2021-07-16 高新 一种多特异性抗体及其制备方法和用途
US12060434B2 (en) * 2020-02-25 2024-08-13 Gensun Biopharma Inc. Trispecific T cell engagers

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