JP2024539141A - 筋ジストロフィーを治療するための組成物及び方法 - Google Patents
筋ジストロフィーを治療するための組成物及び方法 Download PDFInfo
- Publication number
- JP2024539141A JP2024539141A JP2024523627A JP2024523627A JP2024539141A JP 2024539141 A JP2024539141 A JP 2024539141A JP 2024523627 A JP2024523627 A JP 2024523627A JP 2024523627 A JP2024523627 A JP 2024523627A JP 2024539141 A JP2024539141 A JP 2024539141A
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- cre
- mdx
- c1qa
- mice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163270352P | 2021-10-21 | 2021-10-21 | |
| US63/270,352 | 2021-10-21 | ||
| PCT/US2022/078510 WO2023070087A1 (en) | 2021-10-21 | 2022-10-21 | Compositions and methods for treating muscular dystrophy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024539141A true JP2024539141A (ja) | 2024-10-28 |
| JP2024539141A5 JP2024539141A5 (https=) | 2025-10-29 |
Family
ID=86059727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024523627A Pending JP2024539141A (ja) | 2021-10-21 | 2022-10-21 | 筋ジストロフィーを治療するための組成物及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250230225A1 (https=) |
| EP (1) | EP4419144A4 (https=) |
| JP (1) | JP2024539141A (https=) |
| CA (1) | CA3235802A1 (https=) |
| WO (1) | WO2023070087A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117174164B (zh) * | 2023-10-30 | 2024-02-13 | 晨伫(杭州)生物科技有限责任公司 | 基于预测蛋白质-小分子结合姿势筛选先导化合物的方法 |
| EP4670793A1 (en) * | 2024-06-24 | 2025-12-31 | Montis Biosciences BV | C1Q ANTIGEN BINDING MOLECULES |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3019240T3 (da) * | 2013-07-09 | 2024-06-03 | Annexon Inc | Anti-komplementfaktor C1Q antistoffer og anvendelser deraf |
-
2022
- 2022-10-21 JP JP2024523627A patent/JP2024539141A/ja active Pending
- 2022-10-21 US US18/703,211 patent/US20250230225A1/en active Pending
- 2022-10-21 EP EP22884725.7A patent/EP4419144A4/en active Pending
- 2022-10-21 WO PCT/US2022/078510 patent/WO2023070087A1/en not_active Ceased
- 2022-10-21 CA CA3235802A patent/CA3235802A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4419144A4 (en) | 2026-01-14 |
| CA3235802A1 (en) | 2023-04-27 |
| EP4419144A1 (en) | 2024-08-28 |
| US20250230225A1 (en) | 2025-07-17 |
| WO2023070087A1 (en) | 2023-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RD01 | Notification of change of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7426 Effective date: 20241128 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20241128 |
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| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20251017 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20251017 |