JP2024539081A5 - - Google Patents
Info
- Publication number
- JP2024539081A5 JP2024539081A5 JP2024523275A JP2024523275A JP2024539081A5 JP 2024539081 A5 JP2024539081 A5 JP 2024539081A5 JP 2024523275 A JP2024523275 A JP 2024523275A JP 2024523275 A JP2024523275 A JP 2024523275A JP 2024539081 A5 JP2024539081 A5 JP 2024539081A5
- Authority
- JP
- Japan
- Prior art keywords
- agent according
- nucleic acid
- acid sequence
- sequence encoding
- zinc finger
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163257827P | 2021-10-20 | 2021-10-20 | |
| US63/257,827 | 2021-10-20 | ||
| US202263350041P | 2022-06-08 | 2022-06-08 | |
| US202263350039P | 2022-06-08 | 2022-06-08 | |
| US202263350042P | 2022-06-08 | 2022-06-08 | |
| US63/350,039 | 2022-06-08 | ||
| US63/350,041 | 2022-06-08 | ||
| US63/350,042 | 2022-06-08 | ||
| PCT/US2022/047079 WO2023069478A1 (en) | 2021-10-20 | 2022-10-19 | Methods and compositions for rejuvenating cns glial populations by suppression of transcription factors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024539081A JP2024539081A (ja) | 2024-10-28 |
| JP2024539081A5 true JP2024539081A5 (https=) | 2025-10-14 |
Family
ID=84359179
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024523274A Pending JP2024539080A (ja) | 2021-10-20 | 2022-10-19 | グリア前駆細胞を若返らせることによってミエリン欠乏症を処置するための組成物及び方法 |
| JP2024523275A Pending JP2024539081A (ja) | 2021-10-20 | 2022-10-19 | 転写因子の抑圧によってｃｎｓグリア集団を若返らせるための方法及び組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024523274A Pending JP2024539080A (ja) | 2021-10-20 | 2022-10-19 | グリア前駆細胞を若返らせることによってミエリン欠乏症を処置するための組成物及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US12565648B2 (https=) |
| EP (2) | EP4419685A1 (https=) |
| JP (2) | JP2024539080A (https=) |
| AU (2) | AU2022370552A1 (https=) |
| CA (3) | CA3235458A1 (https=) |
| WO (3) | WO2023069478A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023069478A1 (en) * | 2021-10-20 | 2023-04-27 | University Of Rochester | Methods and compositions for rejuvenating cns glial populations by suppression of transcription factors |
| EP4604985A1 (en) * | 2022-10-19 | 2025-08-27 | University of Rochester | Methods and compositions for rejuvenating cns glial populations with bcl11a transcription factor expression |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US748529A (en) | 1903-09-03 | 1903-12-29 | Troy Laundry Machinery Co Ltd | Marking-machine. |
| US5872005A (en) | 1994-11-03 | 1999-02-16 | Cell Genesys Inc. | Packaging cell lines for adeno-associated viral vectors |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| ES2341926T3 (es) | 1998-03-02 | 2010-06-29 | Massachusetts Institute Of Technology | Poliproteinas con dedos de cinc que tienen enlazadores mejorados. |
| US7013219B2 (en) | 1999-01-12 | 2006-03-14 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6794136B1 (en) | 2000-11-20 | 2004-09-21 | Sangamo Biosciences, Inc. | Iterative optimization in the design of binding proteins |
| US20030104526A1 (en) | 1999-03-24 | 2003-06-05 | Qiang Liu | Position dependent recognition of GNN nucleotide triplets by zinc fingers |
| US7030215B2 (en) | 1999-03-24 | 2006-04-18 | Sangamo Biosciences, Inc. | Position dependent recognition of GNN nucleotide triplets by zinc fingers |
| WO2002088346A2 (en) | 2001-05-01 | 2002-11-07 | National Research Council Of Canada | A system for inducible expression in eukaryotic cells |
| WO2003070171A2 (en) | 2002-02-15 | 2003-08-28 | Cornell Research Foundation, Inc. | Myelination of congenitally dysmyelinated forebrains using oligodendrocyte progenitor cells |
| US20040029269A1 (en) | 2002-05-07 | 2004-02-12 | Goldman Steven A | Promoter-based isolation, purification, expansion, and transplantation of neuronal progenitor cells, oligodendrocyte progenitor cells, or neural stem cells from a population of embryonic stem cells |
| US7485291B2 (en) | 2003-06-03 | 2009-02-03 | Cell Genesys, Inc. | Compositions and methods for generating multiple polypeptides from a single vector using a virus derived peptide cleavage site, and uses thereof |
| US8728759B2 (en) | 2004-10-04 | 2014-05-20 | National Research Council Of Canada | Reverse cumate repressor mutant |
| WO2011072246A2 (en) | 2009-12-10 | 2011-06-16 | Regents Of The University Of Minnesota | Tal effector-mediated dna modification |
| EP2951588A4 (en) * | 2013-01-30 | 2016-11-16 | Benaroya Res Inst At Virginia Mason | EFFeCtor T-CELL RESISTANCE |
| HUE053191T2 (hu) | 2017-02-09 | 2021-06-28 | Bayer Ag | 2-Heteroaril-3-oxo-2,3-dihidropiridazin-4-karboxamidok rák kezelésére |
| US12365872B2 (en) * | 2018-09-19 | 2025-07-22 | Lineage Cell Therapeutics, Inc. | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| US20230057355A1 (en) | 2019-02-13 | 2023-02-23 | University Of Rochester | Gene networks that mediate remyelination of the human brain |
| CA3167135A1 (en) | 2020-02-06 | 2021-08-12 | Emerald Health Pharmaceuticals Inc. | Composition and method for the treatment and prevention of cardiac, pulmonary, dermal, and renal fibrosis |
| GB2625500B (en) | 2021-09-21 | 2026-04-01 | Scribe Therapeutics Inc | Engineered CasX repressor systems |
| WO2023069478A1 (en) | 2021-10-20 | 2023-04-27 | University Of Rochester | Methods and compositions for rejuvenating cns glial populations by suppression of transcription factors |
| CA3234809A1 (en) | 2021-10-20 | 2023-04-27 | Steven Goldman | Isolated glial progenitor cells for use in the competition treatment of age-related white matter loss |
-
2022
- 2022-10-19 WO PCT/US2022/047079 patent/WO2023069478A1/en not_active Ceased
- 2022-10-19 JP JP2024523274A patent/JP2024539080A/ja active Pending
- 2022-10-19 WO PCT/US2022/047085 patent/WO2023069484A1/en not_active Ceased
- 2022-10-19 US US17/968,984 patent/US12565648B2/en active Active
- 2022-10-19 US US18/047,744 patent/US20230190961A1/en active Pending
- 2022-10-19 EP EP22823646.9A patent/EP4419685A1/en active Pending
- 2022-10-19 JP JP2024523275A patent/JP2024539081A/ja active Pending
- 2022-10-19 EP EP22803427.8A patent/EP4419679A1/en active Pending
- 2022-10-19 WO PCT/US2022/047083 patent/WO2023069482A1/en not_active Ceased
- 2022-10-19 US US18/047,749 patent/US20230133695A1/en active Pending
- 2022-10-19 CA CA3235458A patent/CA3235458A1/en active Pending
- 2022-10-19 AU AU2022370552A patent/AU2022370552A1/en active Pending
- 2022-10-19 CA CA3235250A patent/CA3235250A1/en active Pending
- 2022-10-19 AU AU2022369984A patent/AU2022369984A1/en active Pending
- 2022-10-19 CA CA3234634A patent/CA3234634A1/en active Pending
-
2023
- 2023-09-14 US US18/467,442 patent/US20240167034A1/en active Pending
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