JP2024534231A - Ｃｋ２媒介リン酸化を阻害する線状ペプチド及びそれを含む組成物 - Google Patents

Ｃｋ２媒介リン酸化を阻害する線状ペプチド及びそれを含む組成物 Download PDF

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JP2024534231A
JP2024534231A JP2024514574A JP2024514574A JP2024534231A JP 2024534231 A JP2024534231 A JP 2024534231A JP 2024514574 A JP2024514574 A JP 2024514574A JP 2024514574 A JP2024514574 A JP 2024514574A JP 2024534231 A JP2024534231 A JP 2024534231A
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seq
peptide
polypeptides
polypeptide
identified
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Pending
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JP2024514574A
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Japanese (ja)
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JP2024534231A5 (enExample
Inventor
ゴンザレス、ヨルダンカ マスフォロール
ペレス、ヒルダ、エリサ ガライ
アコスタ、オズワルド レジェス
ネグリン、ヤセル ペレラ
メネンデス、エヴェリン カバレロ
レぺス、ルイス、ハビエル ゴンザレス
ペレス、ウラジミール、アルマンド ベサーダ
ロドリゲス、シルビオ、エルネスト ペレア
ニエト、ジェラルド、エンリケ ギレン
ブランコ、ソニア ゴンザレス
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Center for Genetic Engineering and Biotechnology
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Center for Genetic Engineering and Biotechnology
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Application filed by Center for Genetic Engineering and Biotechnology filed Critical Center for Genetic Engineering and Biotechnology
Publication of JP2024534231A publication Critical patent/JP2024534231A/ja
Publication of JP2024534231A5 publication Critical patent/JP2024534231A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11001—Non-specific serine/threonine protein kinase (2.7.11.1), i.e. casein kinase or checkpoint kinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
JP2024514574A 2021-07-09 2022-07-07 Ｃｋ２媒介リン酸化を阻害する線状ペプチド及びそれを含む組成物 Pending JP2024534231A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CU2021000058A CU24766B1 (es) 2021-07-09 2021-07-09 Péptidos lineales que inhiben la fosforilación mediada por ck2
CU2021-0058 2021-07-09
PCT/CU2022/050007 WO2023280330A1 (es) 2021-07-09 2022-07-07 Péptidos lineales que inhiben la fosforilación mediada por ck2 y composiciones que los comprenden

Publications (2)

Publication Number Publication Date
JP2024534231A true JP2024534231A (ja) 2024-09-18
JP2024534231A5 JP2024534231A5 (enExample) 2025-05-23

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ID=83080989

Family Applications (1)

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JP2024514574A Pending JP2024534231A (ja) 2021-07-09 2022-07-07 Ｃｋ２媒介リン酸化を阻害する線状ペプチド及びそれを含む組成物

Country Status (11)

Country Link
US (1) US20240317827A1 (enExample)
EP (1) EP4368710A1 (enExample)
JP (1) JP2024534231A (enExample)
KR (1) KR20240032882A (enExample)
CN (1) CN117795064A (enExample)
AR (1) AR126388A1 (enExample)
AU (1) AU2022308094A1 (enExample)
CA (1) CA3225387A1 (enExample)
CU (1) CU24766B1 (enExample)
MX (1) MX2024000542A (enExample)
WO (1) WO2023280330A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118290537B (zh) * 2024-05-09 2025-02-07 永州中古生物技术有限公司 一种在nci-h460细胞系中对ck2起到抑制作用的多肽

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU23225A1 (es) 2001-12-20 2007-08-30 Ct Ingenieria Genetica Biotech PéPTIDOS PARA EL TRATAMIENTO DEL CáNCER ASOCIADO AL VIRUS PAPILOMA HUMANO (VPH) Y DE OTROS TUMORES EPITELIALES
WO2006020207A2 (en) * 2004-07-19 2006-02-23 University Of Cincinnati Compounds for control of appetite
EP2116603A3 (en) * 2004-11-12 2010-02-17 The University Of British Columbia Antimicrobial peptides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SCI REP., vol. 9(1):11018, JPN6026014959, 2019, ISSN: 0005841827 *

Also Published As

Publication number Publication date
CU20210058A7 (es) 2023-02-13
EP4368710A1 (en) 2024-05-15
AR126388A1 (es) 2023-10-11
WO2023280330A1 (es) 2023-01-12
CU24766B1 (es) 2025-08-13
AU2022308094A1 (en) 2024-02-01
KR20240032882A (ko) 2024-03-12
CN117795064A (zh) 2024-03-29
CA3225387A1 (en) 2023-01-12
US20240317827A1 (en) 2024-09-26
MX2024000542A (es) 2024-02-02

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