JP2024527939A5 - - Google Patents
Info
- Publication number
- JP2024527939A5 JP2024527939A5 JP2024504833A JP2024504833A JP2024527939A5 JP 2024527939 A5 JP2024527939 A5 JP 2024527939A5 JP 2024504833 A JP2024504833 A JP 2024504833A JP 2024504833 A JP2024504833 A JP 2024504833A JP 2024527939 A5 JP2024527939 A5 JP 2024527939A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- glycero
- lipid nanoparticle
- nanoparticle composition
- lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163225815P | 2021-07-26 | 2021-07-26 | |
| US63/225,815 | 2021-07-26 | ||
| PCT/US2022/038151 WO2023009421A1 (en) | 2021-07-26 | 2022-07-25 | Processes for preparing lipid nanoparticle compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024527939A JP2024527939A (ja) | 2024-07-26 |
| JP2024527939A5 true JP2024527939A5 (enExample) | 2025-08-04 |
Family
ID=82899410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024504833A Pending JP2024527939A (ja) | 2021-07-26 | 2022-07-25 | 脂質ナノ粒子組成物を調製するためのプロセス |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240335393A1 (enExample) |
| EP (1) | EP4376814A1 (enExample) |
| JP (1) | JP2024527939A (enExample) |
| CN (1) | CN118019527A (enExample) |
| TW (1) | TW202320736A (enExample) |
| WO (1) | WO2023009421A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3675817A1 (en) | 2017-08-31 | 2020-07-08 | Modernatx, Inc. | Methods of making lipid nanoparticles |
| CZ310613B6 (cs) | 2020-09-23 | 2026-01-28 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Lipidoidy pro transfekci nukleových kyselin a jejich použití |
| CZ310443B6 (cs) | 2021-07-19 | 2025-06-25 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití |
| TW202539706A (zh) * | 2023-11-14 | 2025-10-16 | 大陸商上海瑞宏迪醫藥有限公司 | 一種脂質奈米粒的製備方法和應用 |
| CN121099987A (zh) * | 2024-04-08 | 2025-12-09 | 苏州艾博生物科技有限公司 | 脂质纳米颗粒制剂及其制备方法 |
| GB202414932D0 (en) | 2024-10-10 | 2024-11-27 | Apoha Ltd | Method and apparatus |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5681702A (en) | 1994-08-30 | 1997-10-28 | Chiron Corporation | Reduction of nonspecific hybridization by using novel base-pairing schemes |
| WO2006044660A2 (en) * | 2004-10-14 | 2006-04-27 | Vanderbilt University | Functionalized solid lipid nanoparticles and methods of making and using same |
| CN107028886A (zh) * | 2009-11-04 | 2017-08-11 | 不列颠哥伦比亚大学 | 含有核酸的脂质粒子及相关的方法 |
| EP2625189B1 (en) | 2010-10-01 | 2018-06-27 | ModernaTX, Inc. | Engineered nucleic acids and methods of use thereof |
| CA2824526C (en) | 2011-01-11 | 2020-07-07 | Alnylam Pharmaceuticals, Inc. | Pegylated lipids and their use for drug delivery |
| WO2013103659A1 (en) | 2012-01-04 | 2013-07-11 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Stabilizing rna by incorporating chain-terminating nucleosides at the 3'-terminus |
| WO2014093924A1 (en) | 2012-12-13 | 2014-06-19 | Moderna Therapeutics, Inc. | Modified nucleic acid molecules and uses thereof |
| PL2922554T3 (pl) | 2012-11-26 | 2022-06-20 | Modernatx, Inc. | Na zmodyfikowany na końcach |
| US20160022840A1 (en) | 2013-03-09 | 2016-01-28 | Moderna Therapeutics, Inc. | Heterologous untranslated regions for mrna |
| EP2968391A1 (en) | 2013-03-13 | 2016-01-20 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
| CN105143456A (zh) | 2013-03-15 | 2015-12-09 | 不列颠哥伦比亚大学 | 用于转染的脂质纳米粒子和相关方法 |
| US11564893B2 (en) * | 2015-08-17 | 2023-01-31 | Modernatx, Inc. | Methods for preparing particles and related compositions |
| JP6948313B6 (ja) * | 2015-09-17 | 2022-01-14 | モデルナティエックス インコーポレイテッド | 治療剤の細胞内送達のための化合物および組成物 |
| PL3386484T3 (pl) | 2015-12-10 | 2022-07-25 | Modernatx, Inc. | Kompozycje i sposoby dostarczania środków terapeutycznych |
| JP7488193B2 (ja) * | 2018-05-24 | 2024-05-21 | トランスレイト バイオ， インコーポレイテッド | チオエステルカチオン性脂質 |
| HRP20240586T1 (hr) * | 2018-10-09 | 2024-07-19 | The University Of British Columbia | Sastavi i sustavi koji sadrže transfekcijske sposobne vezikle bez organskih otapala i deterdženta i s njim povezanim postupcima |
| AU2020350759A1 (en) * | 2019-09-19 | 2022-03-31 | Modernatx, Inc. | Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents |
-
2022
- 2022-07-25 WO PCT/US2022/038151 patent/WO2023009421A1/en not_active Ceased
- 2022-07-25 EP EP22754668.6A patent/EP4376814A1/en active Pending
- 2022-07-25 TW TW111127849A patent/TW202320736A/zh unknown
- 2022-07-25 JP JP2024504833A patent/JP2024527939A/ja active Pending
- 2022-07-25 US US18/291,707 patent/US20240335393A1/en active Pending
- 2022-07-25 CN CN202280065049.8A patent/CN118019527A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024527939A5 (enExample) | ||
| JP2024527940A5 (enExample) | ||
| JP2023513043A5 (enExample) | ||
| JP2022548304A5 (enExample) | ||
| JP2022548312A5 (enExample) | ||
| JP2022502451A5 (enExample) | ||
| JP2023543963A5 (enExample) | ||
| JP2023538260A5 (enExample) | ||
| JP2022549253A5 (enExample) | ||
| EP2558074B1 (en) | Preparation of lipid nanoparticles | |
| JP2020510072A5 (enExample) | ||
| JP5831588B2 (ja) | リポソームの製造方法 | |
| JP4857392B2 (ja) | リポソームの製造方法ならびにコレステロール溶解方法 | |
| CN103989633A (zh) | 制造脂质体的系统和方法 | |
| RU2660585C2 (ru) | Фармацевтическая композиция для уменьшения осложнений применения стероидных препаратов при лечении офтальмологических заболеваний | |
| CN118319880B (zh) | 靶向肺部高效递送核酸的脂质纳米颗粒、吸入式制剂及应用 | |
| JP2024542099A5 (enExample) | ||
| US12582610B2 (en) | Lipid-polymer compositions and methods of use | |
| WO2024046448A1 (en) | Lyophilized formulations and liquid formulations of lipid nanoparticles | |
| CN115708818B (zh) | 一种用于雾化吸入脂质纳米粒的通用型处方 | |
| JP2024545584A5 (enExample) | ||
| JP2025523587A (ja) | 核酸送達のための局所送達用カチオン性コレステロールを使用した脂質ナノ粒子 | |
| WO2001000173A1 (fr) | Methode de regulation de la fuite de medicaments encapsules dans des liposomes | |
| US8871252B2 (en) | pH-responsive liposome | |
| EP1954243A2 (en) | A method for preparing liposomes and uses thereof |