JP2024527542A5 - - Google Patents

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Publication number
JP2024527542A5
JP2024527542A5 JP2023580484A JP2023580484A JP2024527542A5 JP 2024527542 A5 JP2024527542 A5 JP 2024527542A5 JP 2023580484 A JP2023580484 A JP 2023580484A JP 2023580484 A JP2023580484 A JP 2023580484A JP 2024527542 A5 JP2024527542 A5 JP 2024527542A5
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JP
Japan
Application number
JP2023580484A
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Japanese (ja)
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JPWO2023278589A5 (https=
JP2024527542A (ja
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Publication date
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Priority claimed from PCT/US2022/035539 external-priority patent/WO2023278589A1/en
Publication of JP2024527542A publication Critical patent/JP2024527542A/ja
Publication of JP2024527542A5 publication Critical patent/JP2024527542A5/ja
Publication of JPWO2023278589A5 publication Critical patent/JPWO2023278589A5/ja
Pending legal-status Critical Current

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JP2023580484A 2021-06-30 2022-06-29 結合修飾オリゴマー化合物の合成のための方法 Pending JP2024527542A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163217137P 2021-06-30 2021-06-30
US63/217,137 2021-06-30
PCT/US2022/035539 WO2023278589A1 (en) 2021-06-30 2022-06-29 Method for synthesis of linkage modified oligomeric compounds

Publications (3)

Publication Number Publication Date
JP2024527542A JP2024527542A (ja) 2024-07-25
JP2024527542A5 true JP2024527542A5 (https=) 2025-07-08
JPWO2023278589A5 JPWO2023278589A5 (https=) 2025-07-08

Family

ID=84691597

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023580484A Pending JP2024527542A (ja) 2021-06-30 2022-06-29 結合修飾オリゴマー化合物の合成のための方法

Country Status (6)

Country Link
US (1) US20240287520A1 (https=)
EP (1) EP4363572A4 (https=)
JP (1) JP2024527542A (https=)
KR (1) KR20240027745A (https=)
CN (1) CN117480254A (https=)
WO (1) WO2023278589A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4013767A4 (en) 2019-08-15 2023-10-25 Ionis Pharmaceuticals, Inc. Linkage modified oligomeric compounds and uses thereof
EP4669753A1 (en) 2023-02-20 2025-12-31 ProQR Therapeutics II B.V. Antisense oligonucleotides for the treatment of atherosclerotic cardiovascular disease
WO2024206175A1 (en) 2023-03-24 2024-10-03 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of neurological disorders
GB202304363D0 (en) 2023-03-24 2023-05-10 Proqr Therapeutics Ii Bv Chemically modified antisense oligonucleotides for use in RNA editing
AU2024246572A1 (en) 2023-03-27 2025-10-30 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of liver disease
WO2024220934A1 (en) 2023-04-21 2024-10-24 University Of Rochester Nucleic acid molecules for pseudouridylation
WO2024256620A1 (en) 2023-06-16 2024-12-19 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of neurodegenerative disease
WO2025051946A1 (en) 2023-09-07 2025-03-13 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of metabolic disorders
WO2025072672A2 (en) 2023-09-27 2025-04-03 Judo Bio, Inc. Slc6a19-targeting modulatory nucleic acid agents
WO2025072699A1 (en) 2023-09-27 2025-04-03 Judo Bio, Inc. Aminoglycosides for delivery of agents to the kidney
WO2025072713A1 (en) 2023-09-27 2025-04-03 Judo Bio, Inc. Polymyxins for delivery of agents to the kidney
WO2025104239A1 (en) 2023-11-16 2025-05-22 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of classic galactosemia
WO2025132708A1 (en) 2023-12-20 2025-06-26 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of huntington's disease
WO2025141016A1 (en) * 2023-12-27 2025-07-03 F. Hoffmann-La Roche Ag A method for the synthesis of oligonucleotides with modfied internucleoside linkages
GB202404661D0 (en) 2024-04-02 2024-05-15 Proqr Therapeutics Ii Bv Antisense oligoncleotides for the treatment of liver disease
GB202405143D0 (en) 2024-04-11 2024-05-29 Proqr Therapeutics Ii Bv Antisense oligonucleotides for the treatment of poly-q disease
WO2025224230A1 (en) 2024-04-25 2025-10-30 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of fatty liver disease
WO2025240884A1 (en) * 2024-05-17 2025-11-20 Ionis Pharmaceuticals, Inc. Patterned modified oligonucleotides
WO2025250953A1 (en) * 2024-05-31 2025-12-04 Ionis Pharmaceuticals, Inc. Linkage modified oligomeric agents and uses thereof
GB202410081D0 (en) 2024-07-11 2024-08-28 Proqr Therapeutics Ii Bv Antisense oligonucleotides for the treatment of cardiovascular disease
WO2026022136A1 (en) 2024-07-23 2026-01-29 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of metabolic disorders
WO2026060374A2 (en) 2024-09-16 2026-03-19 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of neurological disorders
WO2026068781A1 (en) 2024-09-30 2026-04-02 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of liver disease
WO2026080897A1 (en) 2024-10-11 2026-04-16 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of chronic pain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2740501C2 (ru) * 2017-02-21 2021-01-14 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) МОДИФИЦИРОВАННЫЕ ОЛИГОНУКЛЕОТИДЫ, АКТИВИРУЮЩИЕ РНКазу Н
EP4013767A4 (en) * 2019-08-15 2023-10-25 Ionis Pharmaceuticals, Inc. Linkage modified oligomeric compounds and uses thereof

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