JP2024526155A5 - - Google Patents

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Publication number
JP2024526155A5
JP2024526155A5 JP2023578891A JP2023578891A JP2024526155A5 JP 2024526155 A5 JP2024526155 A5 JP 2024526155A5 JP 2023578891 A JP2023578891 A JP 2023578891A JP 2023578891 A JP2023578891 A JP 2023578891A JP 2024526155 A5 JP2024526155 A5 JP 2024526155A5
Authority
JP
Japan
Application number
JP2023578891A
Other languages
Japanese (ja)
Other versions
JP2024526155A (ja
JPWO2022271964A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/034754 external-priority patent/WO2022271964A1/en
Publication of JP2024526155A publication Critical patent/JP2024526155A/ja
Publication of JP2024526155A5 publication Critical patent/JP2024526155A5/ja
Publication of JPWO2022271964A5 publication Critical patent/JPWO2022271964A5/ja
Withdrawn legal-status Critical Current

Links

JP2023578891A 2021-06-24 2022-06-23 Erk1/2およびshp2阻害剤の併用療法 Withdrawn JP2024526155A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202163214769P 2021-06-24 2021-06-24
US63/214,769 2021-06-24
US202163277550P 2021-11-09 2021-11-09
US63/277,550 2021-11-09
US202163280521P 2021-11-17 2021-11-17
US63/280,521 2021-11-17
US202263321615P 2022-03-18 2022-03-18
US63/321,615 2022-03-18
PCT/US2022/034754 WO2022271964A1 (en) 2021-06-24 2022-06-23 Erk1/2 and shp2 inhibitors combination therapy

Publications (3)

Publication Number Publication Date
JP2024526155A JP2024526155A (ja) 2024-07-17
JP2024526155A5 true JP2024526155A5 (https=) 2025-06-24
JPWO2022271964A5 JPWO2022271964A5 (https=) 2025-06-24

Family

ID=84545944

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023578891A Withdrawn JP2024526155A (ja) 2021-06-24 2022-06-23 Erk1/2およびshp2阻害剤の併用療法

Country Status (10)

Country Link
US (1) US20240299388A1 (https=)
EP (1) EP4358965A4 (https=)
JP (1) JP2024526155A (https=)
KR (1) KR20240096444A (https=)
AU (1) AU2022300368A1 (https=)
CA (1) CA3222772A1 (https=)
IL (1) IL309401A (https=)
MX (1) MX2023015298A (https=)
TW (1) TW202317124A (https=)
WO (1) WO2022271964A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119136806A (zh) 2022-03-08 2024-12-13 锐新医药公司 用于治疗免疫难治性肺癌的方法
WO2023240263A1 (en) 2022-06-10 2023-12-14 Revolution Medicines, Inc. Macrocyclic ras inhibitors
EP4687905A1 (en) 2023-03-30 2026-02-11 Revolution Medicines, Inc. Compositions for inducing ras gtp hydrolysis and uses thereof
KR20260005904A (ko) 2023-04-07 2026-01-12 레볼루션 메디슨즈, 인크. 매크로사이클릭 ras 억제제
CN121263418A (zh) 2023-04-07 2026-01-02 锐新医药公司 大环ras抑制剂
AU2024252105A1 (en) 2023-04-14 2025-10-16 Revolution Medicines, Inc. Crystalline forms of ras inhibitors, compositions containing the same, and methods of use thereof
KR20250172857A (ko) 2023-04-14 2025-12-09 레볼루션 메디슨즈, 인크. Ras 억제제의 결정형
AU2024265078A1 (en) 2023-05-04 2025-12-11 Revolution Medicines, Inc. Combination therapy for a ras related disease or disorder
IL326136A (en) 2023-08-07 2026-03-01 Revolution Medicines Inc RMC-6291 for use in the treatment of a disease or disorder associated with the RAS protein
US20250154171A1 (en) 2023-10-12 2025-05-15 Revolution Medicines, Inc. Ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
US20250375445A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016205418A1 (en) * 2015-06-15 2016-12-22 Asana Biosciences, Llc Heterocyclic inhibitors of erk1 and erk2 and their use in the treatment of cancer
CA3074690A1 (en) * 2017-09-07 2019-03-14 Revolution Medicines, Inc. Shp2 inhibitor compositions and methods for treating cancer
JP7542538B2 (ja) * 2018-09-18 2024-08-30 ニカング セラピューティクス, インコーポレイテッド Srcホモロジー-2ホスファターゼ阻害剤としての縮合三環式環誘導体
CA3158910A1 (en) * 2019-10-28 2021-05-06 Asana Biosciences, Llc Improved methods, kits, compositions and dosing regimens for the use of heterocyclic inhibitors of erk1 and erk2

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