JP2024521921A5 - - Google Patents
Info
- Publication number
- JP2024521921A5 JP2024521921A5 JP2023574590A JP2023574590A JP2024521921A5 JP 2024521921 A5 JP2024521921 A5 JP 2024521921A5 JP 2023574590 A JP2023574590 A JP 2023574590A JP 2023574590 A JP2023574590 A JP 2023574590A JP 2024521921 A5 JP2024521921 A5 JP 2024521921A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- conjugate
- acceptable salt
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163202273P | 2021-06-03 | 2021-06-03 | |
| US63/202,273 | 2021-06-03 | ||
| US202163282585P | 2021-11-23 | 2021-11-23 | |
| US63/282,585 | 2021-11-23 | ||
| PCT/IB2022/055167 WO2022254376A1 (en) | 2021-06-03 | 2022-06-02 | Neodegrader conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024521921A JP2024521921A (ja) | 2024-06-04 |
| JP2024521921A5 true JP2024521921A5 (cg-RX-API-DMAC10.html) | 2025-06-11 |
Family
ID=84323936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023574590A Pending JP2024521921A (ja) | 2021-06-03 | 2022-06-02 | ネオデグラダーコンジュゲート |
Country Status (14)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7664680B2 (ja) | 2017-03-29 | 2025-04-18 | リガケム バイオサイエンシズ， インク． | ピロロベンゾジアゼピン二量体前駆体及びそのリガンド－リンカーコンジュゲート化合物 |
| KR20250133786A (ko) * | 2023-02-15 | 2025-09-08 | 씨에스피씨 메가리스 바이오파마슈티칼 씨오., 엘티디. | 도마이드계 분자 접착제 유도체 및 이의 용도 |
| JP2026510495A (ja) * | 2023-03-10 | 2026-04-07 | リガケム バイオサイエンシズ， インク． | ヒトｌ１ｃａｍに対する抗体を含む抗体－薬物コンジュゲートおよびその使用 |
| WO2024222841A1 (zh) | 2023-04-27 | 2024-10-31 | 石药集团巨石生物制药有限公司 | 一种抗体药物偶联物 |
| WO2025168071A1 (zh) * | 2024-02-08 | 2025-08-14 | 映恩生物制药（苏州）有限公司 | 一种含氮杂环化合物、其偶联物及其制备方法和用途 |
| WO2025259615A1 (en) * | 2024-06-11 | 2025-12-18 | Triana Biomedicines, Inc. | Modulators of cdk2 and uses thereof |
| WO2026007898A1 (zh) * | 2024-07-01 | 2026-01-08 | 上海海雁医药科技有限公司 | 含苯乙氧基亚烷基胺结构的异吲哚啉化合物、其药物组合物及应用 |
| WO2026041050A1 (zh) * | 2024-08-20 | 2026-02-26 | 海思科医药集团股份有限公司 | 一种配体-蛋白降解剂偶联物及其在医药上的应用 |
| TW202620053A (zh) * | 2024-09-30 | 2026-05-16 | 南韓商歐倫醫療公司 | 抗ｃｄ１２３抗體及新降解劑偶聯物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2957226C (en) * | 2008-10-29 | 2018-08-14 | Celgene Corporation | Isoindoline compounds for use in the treatment of cancer |
| WO2018182341A1 (ko) * | 2017-03-29 | 2018-10-04 | 주식회사 레고켐 바이오사이언스 | 피롤로벤조디아제핀 이량체 전구체 및 이의 리간드-링커 접합체 화합물 |
| JP2022517767A (ja) * | 2019-01-08 | 2022-03-10 | レゲネロン ファーマシューティカルス，インコーポレーテッド | 無痕跡型リンカー及びそのタンパク質－コンジュゲート |
| US20230338564A1 (en) * | 2020-03-31 | 2023-10-26 | Orum Therapeutics, Inc. | Neodegrader conjugates |
| KR20220142393A (ko) * | 2021-04-14 | 2022-10-21 | 주식회사 레고켐 바이오사이언스 | 단백질 분해제 접합체 및 이의 용도 |
| AU2022284372A1 (en) * | 2021-06-03 | 2023-12-14 | Bristol-Myers Squibb Company | Neodegrader-anti-cd33 antibody conjugates |
-
2022
- 2022-06-02 US US18/566,822 patent/US20250090681A1/en active Pending
- 2022-06-02 AU AU2022287316A patent/AU2022287316A1/en active Pending
- 2022-06-02 EP EP22815473.8A patent/EP4346909A4/en active Pending
- 2022-06-02 CN CN202411248905.0A patent/CN119499399A/zh active Pending
- 2022-06-02 TW TW111120734A patent/TW202313124A/zh unknown
- 2022-06-02 WO PCT/IB2022/055167 patent/WO2022254376A1/en not_active Ceased
- 2022-06-02 MX MX2023014284A patent/MX2023014284A/es unknown
- 2022-06-02 KR KR1020247000099A patent/KR20240040067A/ko active Pending
- 2022-06-02 JP JP2023574590A patent/JP2024521921A/ja active Pending
- 2022-06-02 PE PE2023003197A patent/PE20250115A1/es unknown
- 2022-06-02 CN CN202280052606.2A patent/CN118055779A/zh active Pending
- 2022-06-02 CA CA3222182A patent/CA3222182A1/en active Pending
- 2022-06-02 IL IL308811A patent/IL308811A/en unknown
-
2023
- 2023-12-01 CO CONC2023/0016711A patent/CO2023016711A2/es unknown
- 2023-12-01 CL CL2023003604A patent/CL2023003604A1/es unknown
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2026
- 2026-02-10 CL CL2026000398A patent/CL2026000398A1/es unknown