JP2024519955A - 視床内ニューロンにおいて遺伝子発現を調節するための人工発現コンストラクト - Google Patents

視床内ニューロンにおいて遺伝子発現を調節するための人工発現コンストラクト Download PDF

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JP2024519955A
JP2024519955A JP2023572122A JP2023572122A JP2024519955A JP 2024519955 A JP2024519955 A JP 2024519955A JP 2023572122 A JP2023572122 A JP 2023572122A JP 2023572122 A JP2023572122 A JP 2023572122A JP 2024519955 A JP2024519955 A JP 2024519955A
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ehgt
seq
functional
coding sequence
heterologous coding
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JP2024519955A5 (https=
JPWO2022246276A5 (https=
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デイグル，タニア
セバスティアン レイン，エドワード
ピー． レヴィ，ボアズ
ケー． ミック，ジョン
ミッチェル，アマンダ
タシック，ボシリカ
ティン，ジョナサン
ウィード，ナタリー
ゼン，ホンクイ
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アレン インスティテュート
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal

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  • Health & Medical Sciences (AREA)
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JP2023572122A 2021-05-21 2022-05-20 視床内ニューロンにおいて遺伝子発現を調節するための人工発現コンストラクト Pending JP2024519955A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163191832P 2021-05-21 2021-05-21
US63/191,832 2021-05-21
PCT/US2022/030371 WO2022246276A2 (en) 2021-05-21 2022-05-20 Artificial expression constructs for modulating gene expression in neurons within the thalamus

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JP2024519955A true JP2024519955A (ja) 2024-05-21
JP2024519955A5 JP2024519955A5 (https=) 2025-05-27
JPWO2022246276A5 JPWO2022246276A5 (https=) 2025-05-27

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US (1) US20240254514A1 (https=)
EP (1) EP4341410A4 (https=)
JP (1) JP2024519955A (https=)
AU (1) AU2022276538A1 (https=)
CA (1) CA3219142A1 (https=)
WO (1) WO2022246276A2 (https=)

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Publication number Priority date Publication date Assignee Title
WO2023060112A1 (en) * 2021-10-05 2023-04-13 Allen Institute Artificial expression constructs for modulating gene expression in the cerebellum and a secondary cell type

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020508652A (ja) * 2017-02-10 2020-03-26 ザ ロックフェラー ユニバーシティー 薬物標的を特定するための細胞型特異的プロファイリング方法
WO2020168279A2 (en) * 2019-02-15 2020-08-20 Allen Institute Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210395780A1 (en) * 2018-11-05 2021-12-23 Allen Institute Artificial expression constructs for selectively modulating gene expression in excitatory cortical neurons
JP2026509974A (ja) * 2023-02-02 2026-03-26 アレン インスティテュート 脊髄内の細胞の遺伝子発現を調節するための人工発現コンストラクト

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020508652A (ja) * 2017-02-10 2020-03-26 ザ ロックフェラー ユニバーシティー 薬物標的を特定するための細胞型特異的プロファイリング方法
WO2020168279A2 (en) * 2019-02-15 2020-08-20 Allen Institute Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations

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CA3219142A1 (en) 2022-11-24
AU2022276538A1 (en) 2023-11-09
WO2022246276A3 (en) 2022-12-29
US20240254514A1 (en) 2024-08-01
EP4341410A4 (en) 2026-02-11
WO2022246276A2 (en) 2022-11-24
AU2022276538A9 (en) 2023-11-16
EP4341410A2 (en) 2024-03-27

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