JP2024518097A5 - - Google Patents

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Publication number
JP2024518097A5
JP2024518097A5 JP2023570221A JP2023570221A JP2024518097A5 JP 2024518097 A5 JP2024518097 A5 JP 2024518097A5 JP 2023570221 A JP2023570221 A JP 2023570221A JP 2023570221 A JP2023570221 A JP 2023570221A JP 2024518097 A5 JP2024518097 A5 JP 2024518097A5
Authority
JP
Japan
Prior art keywords
conjugate according
group
acid
independently
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023570221A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024518097A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/029292 external-priority patent/WO2022241279A2/en
Publication of JP2024518097A publication Critical patent/JP2024518097A/ja
Publication of JP2024518097A5 publication Critical patent/JP2024518097A5/ja
Pending legal-status Critical Current

Links

JP2023570221A 2021-05-14 2022-05-13 刷子縁膜酵素切断可能リンカーを持つ葉酸受容体標的コンジュゲート並びにガンのイメージング及び治療における使用方法 Pending JP2024518097A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163188910P 2021-05-14 2021-05-14
US63/188,910 2021-05-14
US202263318463P 2022-03-10 2022-03-10
US63/318,463 2022-03-10
PCT/US2022/029292 WO2022241279A2 (en) 2021-05-14 2022-05-13 Folate receptor-targeted conjugates with brush border membrane enzyme-cleavable linkers and methods of use in imaging and treating cancer

Publications (2)

Publication Number Publication Date
JP2024518097A JP2024518097A (ja) 2024-04-24
JP2024518097A5 true JP2024518097A5 (https=) 2025-05-20

Family

ID=84028534

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023570221A Pending JP2024518097A (ja) 2021-05-14 2022-05-13 刷子縁膜酵素切断可能リンカーを持つ葉酸受容体標的コンジュゲート並びにガンのイメージング及び治療における使用方法

Country Status (7)

Country Link
US (1) US20240335570A1 (https=)
EP (1) EP4337265A4 (https=)
JP (1) JP2024518097A (https=)
AU (1) AU2022271866A1 (https=)
CA (1) CA3217981A1 (https=)
MX (1) MX2023013483A (https=)
WO (1) WO2022241279A2 (https=)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004069159A2 (en) * 2003-01-27 2004-08-19 Endocyte, Inc. Vitamin receptor binding drug delivery conjugates
WO2013130776A1 (en) * 2012-02-29 2013-09-06 Purdue Research Foundation Folate receptor alpha binding ligands
WO2014149069A1 (en) * 2013-03-15 2014-09-25 Purdue Research Foundation Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors
US20190298843A1 (en) * 2015-05-11 2019-10-03 Purdue Research Foundation Ligand ionophore conjugates
EP3430383B1 (en) * 2016-03-16 2024-06-26 On Target Laboratories, LLC Ca ix-target nir dyes and their uses
CN118453888A (zh) * 2016-11-16 2024-08-09 普渡研究基金会 配体离子载体共轭物
WO2018178936A1 (en) * 2017-03-30 2018-10-04 Duke University Radiolabeled biomolecules and their use
EP3996715A4 (en) * 2019-07-08 2024-01-03 Purdue Research Foundation COMPOUNDS AND METHODS FOR TREATING AND PREVENTING FIBROTIC DISEASES AND CANCER

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