JP2024514880A5 - - Google Patents

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Publication number
JP2024514880A5
JP2024514880A5 JP2023562909A JP2023562909A JP2024514880A5 JP 2024514880 A5 JP2024514880 A5 JP 2024514880A5 JP 2023562909 A JP2023562909 A JP 2023562909A JP 2023562909 A JP2023562909 A JP 2023562909A JP 2024514880 A5 JP2024514880 A5 JP 2024514880A5
Authority
JP
Japan
Prior art keywords
nucleotides
positions
rnai oligonucleotide
sequence
antisense strand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023562909A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024514880A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/024657 external-priority patent/WO2022221430A1/en
Publication of JP2024514880A publication Critical patent/JP2024514880A/ja
Publication of JP2024514880A5 publication Critical patent/JP2024514880A5/ja
Pending legal-status Critical Current

Links

JP2023562909A 2021-04-14 2022-04-13 Pnpla3発現を調節するための組成物及び方法 Pending JP2024514880A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163174932P 2021-04-14 2021-04-14
US63/174,932 2021-04-14
PCT/US2022/024657 WO2022221430A1 (en) 2021-04-14 2022-04-13 Compositions and methods for modulating pnpla3 expression

Publications (2)

Publication Number Publication Date
JP2024514880A JP2024514880A (ja) 2024-04-03
JP2024514880A5 true JP2024514880A5 (OSRAM) 2025-04-11

Family

ID=81580082

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023562909A Pending JP2024514880A (ja) 2021-04-14 2022-04-13 Pnpla3発現を調節するための組成物及び方法

Country Status (13)

Country Link
US (2) US12084662B2 (OSRAM)
EP (1) EP4323519A1 (OSRAM)
JP (1) JP2024514880A (OSRAM)
KR (1) KR20230171431A (OSRAM)
CN (1) CN117120613A (OSRAM)
AR (1) AR125351A1 (OSRAM)
AU (1) AU2022258459A1 (OSRAM)
BR (1) BR112023021109A2 (OSRAM)
CA (1) CA3209418A1 (OSRAM)
IL (1) IL307625A (OSRAM)
MX (1) MX2023012216A (OSRAM)
TW (2) TW202500748A (OSRAM)
WO (1) WO2022221430A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022221430A1 (en) 2021-04-14 2022-10-20 Dicerna Pharmaceuticals, Inc. Compositions and methods for modulating pnpla3 expression
KR20250110896A (ko) 2022-11-23 2025-07-21 일라이 릴리 앤드 캄파니 4'-포스페이트 유사체 뉴클레오티드 포스포르아미다이트의 합성 방법
KR20250099265A (ko) 2022-11-23 2025-07-01 일라이 릴리 앤드 캄파니 표적화 리간드-접합된 뉴클레오티드 포스포르아미다이트의 합성 방법
WO2024182446A2 (en) * 2023-02-28 2024-09-06 Aligos Therapeutics, Inc. Pnpla3-targeting short interfering rna (sirna) molecules and uses thereof

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WO2016130806A2 (en) * 2015-02-13 2016-08-18 Alnylam Pharmaceuticals, Inc. Patatin-like phospholipase domain containing 3 (pnpla3) irna compositions and methods of use thereof
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UY38003A (es) * 2017-12-12 2019-06-28 Amgen Inc Construcciones de arni para inhibir la expresión de pnpla3 y métodos de uso de las mismas
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KR20210102932A (ko) * 2018-12-10 2021-08-20 암젠 인크 Pnpla3 발현을 억제하기 위한 rnai 작제물 및 이의 사용 방법
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WO2022221430A1 (en) 2021-04-14 2022-10-20 Dicerna Pharmaceuticals, Inc. Compositions and methods for modulating pnpla3 expression

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