JP2024512255A - 部分性脂肪萎縮症を診断および処置するための方法 - Google Patents

部分性脂肪萎縮症を診断および処置するための方法 Download PDF

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JP2024512255A
JP2024512255A JP2023550240A JP2023550240A JP2024512255A JP 2024512255 A JP2024512255 A JP 2024512255A JP 2023550240 A JP2023550240 A JP 2023550240A JP 2023550240 A JP2023550240 A JP 2023550240A JP 2024512255 A JP2024512255 A JP 2024512255A
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chain variable
variable region
fat percentage
amino acid
seq
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JP2024512255A5 (https=
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ウェンジュン チェン
チャールズ ハリス
ブレット ムッサー
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4869—Determining body composition
    • A61B5/4872—Body fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/48—Diagnostic techniques
    • A61B6/482—Diagnostic techniques involving multiple energy imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5217—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
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  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Data Mining & Analysis (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Artificial Intelligence (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dentistry (AREA)
  • Software Systems (AREA)
  • Bioethics (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Evolutionary Computation (AREA)
JP2023550240A 2021-02-22 2022-02-22 部分性脂肪萎縮症を診断および処置するための方法 Pending JP2024512255A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163152100P 2021-02-22 2021-02-22
US63/152,100 2021-02-22
PCT/US2022/017222 WO2022178382A1 (en) 2021-02-22 2022-02-22 Method for diagnosing and treating partial lipodystrophy

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JP2024512255A true JP2024512255A (ja) 2024-03-19
JP2024512255A5 JP2024512255A5 (https=) 2025-02-13

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JP2023550240A Pending JP2024512255A (ja) 2021-02-22 2022-02-22 部分性脂肪萎縮症を診断および処置するための方法

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US (1) US20240153638A1 (https=)
EP (1) EP4294257B1 (https=)
JP (1) JP2024512255A (https=)
DK (1) DK4294257T3 (https=)
ES (1) ES3055018T3 (https=)
FI (1) FI4294257T3 (https=)
HR (1) HRP20251599T1 (https=)
LT (1) LT4294257T (https=)
PL (1) PL4294257T3 (https=)
PT (1) PT4294257T (https=)
RS (1) RS67523B1 (https=)
SI (1) SI4294257T1 (https=)
SM (1) SMT202500444T1 (https=)
WO (1) WO2022178382A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021013807A2 (pt) 2019-01-18 2021-11-30 Astrazeneca Ab Inibidores de pcsk9 e seus métodos de uso
MX2021008661A (es) 2019-01-18 2021-08-19 Astrazeneca Ab Inhibidores de la pcsk9 y metodos de uso de los mismos.
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202417497A (zh) 2015-10-12 2024-05-01 美商再生元醫藥公司 活化瘦素受體的抗原結合蛋白
PT3773713T (pt) * 2018-04-06 2025-07-29 Regeneron Pharma Anticorpo agonista do recetor de leptina para usar no aumento da massa óssea num sujeito que sofre de disfunção metabólica ou de hipoleptinemia

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AJLUNI ET AL.: "Spectrum of disease associated with partial lipodystrophy: lessons from a trial cohort", CLINICAL ENDOCRINOLOGY, vol. 86, JPN6026012947, 2017, pages 698 - 707, ISSN: 0005828940 *
AKINCI ET AL.: "The Treatment of Partial Lipodystrophy in the Setting of Neutralizing Antibody Against Metreleptin w", JOURNAL OF THE ENDOCRINE SOCIETY, vol. 4, JPN7026001417, 2020, pages 544, ISSN: 0005828941 *

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Publication number Publication date
WO2022178382A1 (en) 2022-08-25
SI4294257T1 (sl) 2026-01-30
US20240153638A1 (en) 2024-05-09
HRP20251599T1 (hr) 2026-01-30
DK4294257T3 (da) 2025-12-08
SMT202500444T1 (it) 2026-01-12
RS67523B1 (sr) 2026-01-30
PL4294257T3 (pl) 2026-02-09
EP4294257A1 (en) 2023-12-27
FI4294257T3 (fi) 2025-12-19
LT4294257T (lt) 2025-12-29
PT4294257T (pt) 2025-11-28
EP4294257B1 (en) 2025-11-05
ES3055018T3 (en) 2026-02-09

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