JP2024510539A - ベースコールのためのタイル位置及び／又はサイクルベースの重みセット選択 - Google Patents

ベースコールのためのタイル位置及び／又はサイクルベースの重みセット選択 Download PDF

Info

Publication number
JP2024510539A
JP2024510539A JP2022580969A JP2022580969A JP2024510539A JP 2024510539 A JP2024510539 A JP 2024510539A JP 2022580969 A JP2022580969 A JP 2022580969A JP 2022580969 A JP2022580969 A JP 2022580969A JP 2024510539 A JP2024510539 A JP 2024510539A
Authority
JP
Japan
Prior art keywords
weights
weight
sensing
data
cycles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022580969A
Other languages
English (en)
Japanese (ja)
Inventor
ギャヴィン・デレク・パーナビー
マーク・デイヴィッド・ハーム
アンドリュー・クリストファー・デュ・プリーズ
ドルナ・カシフハギギ
キショール・ジャガナタン
Original Assignee
イルミナ インコーポレイテッド
イルミナ ソフトウェア， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/687,583 external-priority patent/US20220300811A1/en
Application filed by イルミナ インコーポレイテッド, イルミナ ソフトウェア， インコーポレイテッド filed Critical イルミナ インコーポレイテッド
Priority claimed from PCT/US2022/020460 external-priority patent/WO2022197752A1/en
Publication of JP2024510539A publication Critical patent/JP2024510539A/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/04—Architecture, e.g. interconnection topology
    • G06N3/045—Combinations of networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/06—Physical realisation, i.e. hardware implementation of neural networks, neurons or parts of neurons
    • G06N3/063—Physical realisation, i.e. hardware implementation of neural networks, neurons or parts of neurons using electronic means
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/04—Architecture, e.g. interconnection topology
    • G06N3/048—Activation functions

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • Artificial Intelligence (AREA)
  • Biomedical Technology (AREA)
  • Software Systems (AREA)
  • Evolutionary Computation (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Computing Systems (AREA)
  • Computational Linguistics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Mathematical Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Neurology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioethics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compression, Expansion, Code Conversion, And Decoders (AREA)
  • Road Signs Or Road Markings (AREA)
  • Road Paving Structures (AREA)
  • Pens And Brushes (AREA)
  • Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
JP2022580969A 2021-03-16 2022-03-15 ベースコールのためのタイル位置及び／又はサイクルベースの重みセット選択 Pending JP2024510539A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202163161880P 2021-03-16 2021-03-16
US202163161896P 2021-03-16 2021-03-16
US63/161,880 2021-03-16
US63/161,896 2021-03-16
US17/687,583 US20220300811A1 (en) 2021-03-16 2022-03-04 Neural network parameter quantization for base calling
US17/687,551 US20220301657A1 (en) 2021-03-16 2022-03-04 Tile location and/or cycle based weight set selection for base calling
US17/687,583 2022-03-04
US17/687,551 2022-03-04
PCT/US2022/020460 WO2022197752A1 (en) 2021-03-16 2022-03-15 Tile location and/or cycle based weight set selection for base calling

Publications (1)

Publication Number Publication Date
JP2024510539A true JP2024510539A (ja) 2024-03-08

Family

ID=85057463

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022580969A Pending JP2024510539A (ja) 2021-03-16 2022-03-15 ベースコールのためのタイル位置及び／又はサイクルベースの重みセット選択

Country Status (7)

Country Link
EP (2) EP4309179A1 (ko)
JP (1) JP2024510539A (ko)
KR (1) KR20230157230A (ko)
CN (2) CN115699019A (ko)
AU (2) AU2022238841A1 (ko)
CA (2) CA3183567A1 (ko)
IL (1) IL299077A (ko)

Also Published As

Publication number Publication date
EP4309080A1 (en) 2024-01-24
AU2022237501A1 (en) 2023-02-02
CN115803815A (zh) 2023-03-14
IL299077A (en) 2023-02-01
KR20230157230A (ko) 2023-11-16
EP4309179A1 (en) 2024-01-24
AU2022238841A1 (en) 2023-02-02
CA3183581A1 (en) 2022-09-22
CA3183567A1 (en) 2022-09-22
CN115699019A (zh) 2023-02-03

Similar Documents

Publication Publication Date Title
US20220301657A1 (en) Tile location and/or cycle based weight set selection for base calling
CA3168451A1 (en) Knowledge distillation and gradient pruning-based compression of artificial intelligence-based base caller
US20210265015A1 (en) Hardware Execution and Acceleration of Artificial Intelligence-Based Base Caller
US20230041989A1 (en) Base calling using multiple base caller models
JP2024510539A (ja) ベースコールのためのタイル位置及び／又はサイクルベースの重みセット選択
US20230029970A1 (en) Quality score calibration of basecalling systems
WO2022197752A1 (en) Tile location and/or cycle based weight set selection for base calling
US20220415445A1 (en) Self-learned base caller, trained using oligo sequences
US20230026084A1 (en) Self-learned base caller, trained using organism sequences
KR20240035413A (ko) 다중 염기 호출자 모델을 사용한 염기 호출
WO2023009758A1 (en) Quality score calibration of basecalling systems
KR20240027608A (ko) 유기체 서열을 사용하여 훈련된 자체-학습 염기 호출자
CN117546248A (zh) 使用多个碱基检出器模型的碱基检出
CN117529780A (zh) 碱基检出系统的质量分数校准
CN117546249A (zh) 使用寡核苷酸序列训练的自学碱基检出器