JP2024509376A - 家族性ヘテロ接合型及びホモ接合型高コレステロール血症のシクロデキストリンによる治療方法 - Google Patents

家族性ヘテロ接合型及びホモ接合型高コレステロール血症のシクロデキストリンによる治療方法 Download PDF

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JP2024509376A
JP2024509376A JP2023549551A JP2023549551A JP2024509376A JP 2024509376 A JP2024509376 A JP 2024509376A JP 2023549551 A JP2023549551 A JP 2023549551A JP 2023549551 A JP2023549551 A JP 2023549551A JP 2024509376 A JP2024509376 A JP 2024509376A
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cyclodextrin
cholesterol
beta
hydroxypropyl
days
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JP2024509376A5 (https=
Inventor
カーウィン，ダイアナ
カム，ジェイソン
ダッカーズ，ヘンリカス
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ベレン セラピューティクス ピー．ビー．シー．
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Publication of JP2024509376A publication Critical patent/JP2024509376A/ja
Publication of JP2024509376A5 publication Critical patent/JP2024509376A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2023549551A 2021-02-18 2022-02-18 家族性ヘテロ接合型及びホモ接合型高コレステロール血症のシクロデキストリンによる治療方法 Pending JP2024509376A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163150908P 2021-02-18 2021-02-18
US63/150,908 2021-02-18
PCT/US2022/017090 WO2022178318A1 (en) 2021-02-18 2022-02-18 Methods for the treatment of familial heterozygous and homozygous hypercholesterolemia with cyclodextrins

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JP2024509376A true JP2024509376A (ja) 2024-03-01
JP2024509376A5 JP2024509376A5 (https=) 2025-02-27

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JP2023549551A Pending JP2024509376A (ja) 2021-02-18 2022-02-18 家族性ヘテロ接合型及びホモ接合型高コレステロール血症のシクロデキストリンによる治療方法

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US (2) US20220260597A1 (https=)
EP (1) EP4294403A4 (https=)
JP (1) JP2024509376A (https=)
AU (1) AU2022222756A1 (https=)
WO (1) WO2022178318A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024053812A1 (en) * 2022-09-08 2024-03-14 Renatus Inc. Methods for the treatment of chronic kidney disease

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005067904A1 (ja) * 2004-01-15 2005-07-28 Aska Pharmaceutical Co., Ltd. Ａｂｃａ１安定化剤
JP2016166179A (ja) * 2010-04-16 2016-09-15 カンバーランド ファーマシューティカルズ，インコーポレーテッド 安定化スタチン製剤
JP2019504178A (ja) * 2016-01-21 2019-02-14 アテン・ポラス・ライフサイエンシズ シクロデキストリンを主体とするポリマー、その方法、組成物、及び応用

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Publication number Priority date Publication date Assignee Title
US6773719B2 (en) * 1994-03-04 2004-08-10 Esperion Luv Development, Inc. Liposomal compositions, and methods of using liposomal compositions to treat dislipidemias
AU773385B2 (en) * 1999-05-14 2004-05-27 Esperion Luv Development, Inc. Method of treating angina and/or anginal equivalents, and pharmaceutical compositions and kit related thereto
WO2001055301A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
CA2737924A1 (en) * 2008-10-06 2010-04-15 Joshua Robert Schultz Methods of treating inflammation
WO2011116245A2 (en) * 2010-03-19 2011-09-22 Carolus Therapeutics, Inc. Methods of treating inflammation
MX371073B (es) * 2012-04-13 2020-01-15 L&F Res Llc Método para utilizar ciclodextrina.
CN107854448A (zh) * 2017-11-06 2018-03-30 广州市桐晖药业有限公司 一种烟酸片及其制备方法
EP3870181B1 (en) * 2018-10-26 2024-08-14 Keros Therapeutics, Inc. Crystal forms of an alk2 inhibitor
KR20230096975A (ko) * 2020-08-27 2023-06-30 베렌 테라퓨틱스 피.비.씨. 사이클로덱스트린을 이용한 콜레스테롤 결정 색전증 치료 방법

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005067904A1 (ja) * 2004-01-15 2005-07-28 Aska Pharmaceutical Co., Ltd. Ａｂｃａ１安定化剤
JP2016166179A (ja) * 2010-04-16 2016-09-15 カンバーランド ファーマシューティカルズ，インコーポレーテッド 安定化スタチン製剤
JP2019504178A (ja) * 2016-01-21 2019-02-14 アテン・ポラス・ライフサイエンシズ シクロデキストリンを主体とするポリマー、その方法、組成物、及び応用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
INT J MOL SCI, vol. 16(9):21056-21069, JPN6026004567, 2015, ISSN: 0005793325 *
OBESITY, vol. 19(6):1200-1204, JPN6026004564, 2011, ISSN: 0005793326 *

Also Published As

Publication number Publication date
US20230375576A1 (en) 2023-11-23
EP4294403A4 (en) 2024-12-11
WO2022178318A1 (en) 2022-08-25
EP4294403A1 (en) 2023-12-27
US20220260597A1 (en) 2022-08-18
AU2022222756A1 (en) 2023-09-14

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