JP2024506953A - Ｐｌａｑｕｅ乾癬、アトピー性皮膚炎、放射線性皮膚炎の治療におけるタピナロフの改善効果 - Google Patents

Ｐｌａｑｕｅ乾癬、アトピー性皮膚炎、放射線性皮膚炎の治療におけるタピナロフの改善効果 Download PDF

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JP2024506953A
JP2024506953A JP2023549892A JP2023549892A JP2024506953A JP 2024506953 A JP2024506953 A JP 2024506953A JP 2023549892 A JP2023549892 A JP 2023549892A JP 2023549892 A JP2023549892 A JP 2023549892A JP 2024506953 A JP2024506953 A JP 2024506953A
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tapinarov
week
psoriasis
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JP2024506953A5 (https=
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スコット ルーベンステイン デイビッド
アン マクヘイル キンバリー
シー ピシテッリ スティーブン
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Dermavant Sciences GmbH
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Dermavant Sciences GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2023549892A 2021-02-17 2022-02-17 Ｐｌａｑｕｅ乾癬、アトピー性皮膚炎、放射線性皮膚炎の治療におけるタピナロフの改善効果 Pending JP2024506953A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202163150204P 2021-02-17 2021-02-17
US63/150,204 2021-02-17
US202163260322P 2021-08-17 2021-08-17
US63/260,322 2021-08-17
US202163261523P 2021-09-23 2021-09-23
US63/261,523 2021-09-23
US202263266535P 2022-01-07 2022-01-07
US63/266,535 2022-01-07
PCT/US2022/016819 WO2022178144A1 (en) 2021-02-17 2022-02-17 Remittive effects of tapinarof in the treatment of plaque psoriasis, atopic dermatitis, or radiation dermatitis

Publications (2)

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JP2024506953A true JP2024506953A (ja) 2024-02-15
JP2024506953A5 JP2024506953A5 (https=) 2024-03-22

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JP2023549892A Pending JP2024506953A (ja) 2021-02-17 2022-02-17 Ｐｌａｑｕｅ乾癬、アトピー性皮膚炎、放射線性皮膚炎の治療におけるタピナロフの改善効果

Country Status (6)

Country Link
US (2) US20240315985A1 (https=)
EP (1) EP4294518A4 (https=)
JP (1) JP2024506953A (https=)
AU (1) AU2022223701A1 (https=)
CA (1) CA3208742A1 (https=)
WO (1) WO2022178144A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11497718B2 (en) 2018-11-13 2022-11-15 Dermavant Sciences GmbH Use of tapinarof for the treatment of atopic dermatitis
JP2025532421A (ja) * 2022-10-10 2025-09-29 上海澤徳曼医薬科技有限公司 潰瘍を予防及び又は治療するためのスチルベン誘導体の使用
WO2024125500A1 (zh) * 2022-12-14 2024-06-20 上海泽德曼医药科技有限公司 一种局部药物组合物及其在医药上的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200147001A1 (en) * 2018-11-13 2020-05-14 Dermavant Sciences GmbH Use of tapinarof for the treatment of atopic dermatitis
US20200147000A1 (en) * 2018-11-13 2020-05-14 Dermavant Sciences GmbH Use of tapinarof for the treatment of chronic plaque psoriasis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3297605T (pt) * 2015-05-21 2022-05-30 Dermavant Sciences GmbH Composições farmacêuticas tópicas

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200147001A1 (en) * 2018-11-13 2020-05-14 Dermavant Sciences GmbH Use of tapinarof for the treatment of atopic dermatitis
US20200147000A1 (en) * 2018-11-13 2020-05-14 Dermavant Sciences GmbH Use of tapinarof for the treatment of chronic plaque psoriasis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"Dermavant Reports Positive Phase 3 Results for Tapinar of Cream in Adult Patients with Plaque Psoria", STUDY RECORDVERSION 7, JPN6026012944, 26 August 2020 (2020-08-26), ISSN: 0005834502 *
KEVIN ROBBINS ET AL.: ""Phase 2, randomizeddose-finding study of tapinarof (GSK2894512 cream) for the treatment of plaquep", JOURNAL OF THE AMERICAN ACADEMY OFDERMATOLOGY, vol. 80, no. 3, JPN6026012945, March 2019 (2019-03-01), pages 714 - 721, ISSN: 0005834503 *
LINDA STEIN GOLD ET AL.: ""A phase 2b,randomized clinical trial of tapinarof cream for the treatment of plaquepsoriasis: Seco", JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, vol. 84, no. 3, JPN6026012946, March 2021 (2021-03-01), pages 624 - 631, ISSN: 0005834504 *

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Publication number Publication date
EP4294518A1 (en) 2023-12-27
WO2022178144A1 (en) 2022-08-25
EP4294518A4 (en) 2025-01-08
US20240315985A1 (en) 2024-09-26
US20220265572A1 (en) 2022-08-25
AU2022223701A1 (en) 2023-09-07
CA3208742A1 (en) 2022-08-25

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