JP2024505678A - 免疫療法のためのリンパ球活性化遺伝子３（ｌａｇ３）組成物及び方法 - Google Patents

免疫療法のためのリンパ球活性化遺伝子３（ｌａｇ３）組成物及び方法 Download PDF

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JP2024505678A
JP2024505678A JP2023547397A JP2023547397A JP2024505678A JP 2024505678 A JP2024505678 A JP 2024505678A JP 2023547397 A JP2023547397 A JP 2023547397A JP 2023547397 A JP2023547397 A JP 2023547397A JP 2024505678 A JP2024505678 A JP 2024505678A
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chr16
chr5
sequence
tim3
cell
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ライアン コーク，ダニエル
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インテリア セラピューティクス，インコーポレイテッド
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    • A—HUMAN NECESSITIES
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N2310/00—Structure or type of the nucleic acid
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  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • Cell Biology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2023547397A 2021-02-08 2022-02-07 免疫療法のためのリンパ球活性化遺伝子３（ｌａｇ３）組成物及び方法 Pending JP2024505678A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163147223P 2021-02-08 2021-02-08
US63/147,223 2021-02-08
PCT/US2022/015498 WO2022170194A2 (en) 2021-02-08 2022-02-07 Lymphocyte activation gene 3 (lag3) compositions and methods for immunotherapy

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JP2024505678A true JP2024505678A (ja) 2024-02-07
JP2024505678A5 JP2024505678A5 (https=) 2025-02-21

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JP2023547397A Pending JP2024505678A (ja) 2021-02-08 2022-02-07 免疫療法のためのリンパ球活性化遺伝子３（ｌａｇ３）組成物及び方法

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US (1) US20230383253A1 (https=)
EP (1) EP4288088A2 (https=)
JP (1) JP2024505678A (https=)
CN (1) CN117042793A (https=)
WO (1) WO2022170194A2 (https=)

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WO2025128871A2 (en) 2023-12-13 2025-06-19 Renagade Therapeutics Management Inc. Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents

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WO2022170194A2 (en) 2022-08-11
WO2022170194A3 (en) 2022-09-22
EP4288088A2 (en) 2023-12-13
CN117042793A (zh) 2023-11-10
US20230383253A1 (en) 2023-11-30

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