JP2024071393A5 - - Google Patents
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- JP2024071393A5 JP2024071393A5 JP2024030027A JP2024030027A JP2024071393A5 JP 2024071393 A5 JP2024071393 A5 JP 2024071393A5 JP 2024030027 A JP2024030027 A JP 2024030027A JP 2024030027 A JP2024030027 A JP 2024030027A JP 2024071393 A5 JP2024071393 A5 JP 2024071393A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- cancer
- use according
- antibody
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2024097 | 2019-10-24 | ||
| NL2024097 | 2019-10-24 | ||
| PCT/NL2020/050656 WO2021080428A1 (en) | 2019-10-24 | 2020-10-23 | Means and methods for treating subjects with her2 and her3 positive cancer |
| JP2022523992A JP7532514B2 (ja) | 2019-10-24 | 2020-10-23 | Ｈｅｒ２及びｈｅｒ３陽性癌に罹患している対象を治療するための手段及び方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523992A Division JP7532514B2 (ja) | 2019-10-24 | 2020-10-23 | Ｈｅｒ２及びｈｅｒ３陽性癌に罹患している対象を治療するための手段及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024071393A JP2024071393A (ja) | 2024-05-24 |
| JP2024071393A5 true JP2024071393A5 (https=) | 2024-11-12 |
| JP7678175B2 JP7678175B2 (ja) | 2025-05-15 |
Family
ID=68807359
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523992A Active JP7532514B2 (ja) | 2019-10-24 | 2020-10-23 | Ｈｅｒ２及びｈｅｒ３陽性癌に罹患している対象を治療するための手段及び方法 |
| JP2024030027A Active JP7678175B2 (ja) | 2019-10-24 | 2024-02-29 | Ｈｅｒ２及びｈｅｒ３陽性癌に罹患している対象を治療するための手段及び方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523992A Active JP7532514B2 (ja) | 2019-10-24 | 2020-10-23 | Ｈｅｒ２及びｈｅｒ３陽性癌に罹患している対象を治療するための手段及び方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220372166A1 (https=) |
| EP (1) | EP4048702A1 (https=) |
| JP (2) | JP7532514B2 (https=) |
| KR (1) | KR20220103954A (https=) |
| CN (2) | CN116327919A (https=) |
| AU (1) | AU2020371040C1 (https=) |
| CA (1) | CA3158609A1 (https=) |
| TW (1) | TWI873210B (https=) |
| WO (1) | WO2021080428A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200291130A1 (en) * | 2017-03-31 | 2020-09-17 | Merus N.V. | Antibodies for the treatment of erbb-2/erbb-3 positive tumors |
| US20240026029A1 (en) * | 2020-11-04 | 2024-01-25 | Merus N.V. | Means and methods for treating subjects with erbb3 mutation positive cancer |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG192775A1 (en) * | 2011-03-15 | 2013-09-30 | Merrimack Pharmaceuticals Inc | Overcoming resistance to erbb pathway inhibitors |
| SI2838917T1 (sl) | 2012-04-20 | 2019-11-29 | Merus Nv | Postopki in sredstva za produkcijo heterodimernih IG-podobnih molekul |
| US20150203591A1 (en) * | 2012-08-02 | 2015-07-23 | Regeneron Pharmaceuticals, Inc. | Mutivalent antigen-binding proteins |
| IL301147A (en) * | 2014-02-28 | 2023-05-01 | Merus Nv | An antibody that binds to ErbB-2 and ErbB-3 |
| EP3786186A1 (en) * | 2014-02-28 | 2021-03-03 | Merus N.V. | Antibodies that bind egfr and erbb3 |
| US20210206875A1 (en) * | 2017-03-31 | 2021-07-08 | Merus N.V. | Erbb-2 targeting agent and a bispecific antibody with antigen-binding sites that bind an epitope on an extracellular part of erb-2 and erbb-3, for treatment of an individual with an erbb-2, erbb-2/erbb-3 positive tumour |
| AU2018246873B2 (en) * | 2017-03-31 | 2021-05-06 | Merus B.V. | ErbB-2 and ErbB3 binding bispecific antibodies for use in the treatment f cells that have an NRG1 fusion gene |
| WO2018212656A1 (en) * | 2017-05-17 | 2018-11-22 | Merus N.V. | Combination of an erbb-2/erbb-3 bispecific antibody with endocrine therapy for breast cancer |
| US20240026029A1 (en) * | 2020-11-04 | 2024-01-25 | Merus N.V. | Means and methods for treating subjects with erbb3 mutation positive cancer |
-
2020
- 2020-10-23 WO PCT/NL2020/050656 patent/WO2021080428A1/en not_active Ceased
- 2020-10-23 US US17/755,196 patent/US20220372166A1/en active Pending
- 2020-10-23 TW TW109136884A patent/TWI873210B/zh active
- 2020-10-23 EP EP20801415.9A patent/EP4048702A1/en active Pending
- 2020-10-23 CN CN202211199242.9A patent/CN116327919A/zh active Pending
- 2020-10-23 KR KR1020227016799A patent/KR20220103954A/ko active Pending
- 2020-10-23 JP JP2022523992A patent/JP7532514B2/ja active Active
- 2020-10-23 CN CN202080083392.6A patent/CN114761436A/zh active Pending
- 2020-10-23 AU AU2020371040A patent/AU2020371040C1/en active Active
- 2020-10-23 CA CA3158609A patent/CA3158609A1/en active Pending
-
2024
- 2024-02-29 JP JP2024030027A patent/JP7678175B2/ja active Active
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