JP2023543131A - シクロデキストリンによる心血管疾患の治療方法 - Google Patents

シクロデキストリンによる心血管疾患の治療方法 Download PDF

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Publication number
JP2023543131A
JP2023543131A JP2023513670A JP2023513670A JP2023543131A JP 2023543131 A JP2023543131 A JP 2023543131A JP 2023513670 A JP2023513670 A JP 2023513670A JP 2023513670 A JP2023513670 A JP 2023513670A JP 2023543131 A JP2023543131 A JP 2023543131A
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JP
Japan
Prior art keywords
cyclodextrin
therapeutically effective
hydroxypropyl
administration
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2023513670A
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English (en)
Japanese (ja)
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JP2023543131A5 (https=
Inventor
カーウィン，ダイアナ
カム，ジェイソン
Original Assignee
ベレン セラピューティクス ピー．ビー．シー．
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Publication of JP2023543131A publication Critical patent/JP2023543131A/ja
Publication of JP2023543131A5 publication Critical patent/JP2023543131A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2023513670A 2020-08-27 2021-08-27 シクロデキストリンによる心血管疾患の治療方法 Pending JP2023543131A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063071257P 2020-08-27 2020-08-27
US63/071,257 2020-08-27
PCT/US2021/048084 WO2022047249A1 (en) 2020-08-27 2021-08-27 Methods for the treatment of cardiovascular disease with cyclodextrins

Publications (2)

Publication Number Publication Date
JP2023543131A true JP2023543131A (ja) 2023-10-13
JP2023543131A5 JP2023543131A5 (https=) 2024-08-13

Family

ID=80353287

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023513670A Pending JP2023543131A (ja) 2020-08-27 2021-08-27 シクロデキストリンによる心血管疾患の治療方法

Country Status (14)

Country Link
US (2) US20240000826A1 (https=)
EP (1) EP4203974A4 (https=)
JP (1) JP2023543131A (https=)
KR (1) KR20230104119A (https=)
CN (1) CN116322644A (https=)
AU (1) AU2021331487A1 (https=)
CA (1) CA3189915A1 (https=)
CO (1) CO2023003656A2 (https=)
CR (1) CR20230135A (https=)
IL (1) IL300805A (https=)
JO (1) JOP20230043A1 (https=)
MX (1) MX2023002418A (https=)
PE (1) PE20231169A1 (https=)
WO (1) WO2022047249A1 (https=)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877778A (en) * 1987-07-01 1989-10-31 The Children's Medical Center Corporation Method of enhancing lipophile transport using cyclodextrin derivatives
US20190262385A1 (en) * 2012-04-13 2019-08-29 L&F Research Llc Method of using cyclodextrin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877778A (en) * 1987-07-01 1989-10-31 The Children's Medical Center Corporation Method of enhancing lipophile transport using cyclodextrin derivatives
US20190262385A1 (en) * 2012-04-13 2019-08-29 L&F Research Llc Method of using cyclodextrin

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, vol. 73, no. 5, JPN6025039285, 2019, pages 334 - 342, ISSN: 0005697452 *
MOLECULES, vol. 21, JPN6025039283, 2016, pages 1748, ISSN: 0005697450 *
REJUVENATION RESEARCH, vol. 19, no. 3, JPN6025039281, 2016, pages 252 - 255, ISSN: 0005697449 *
SCIENCE TRANSLATIONAL MEDICINE, vol. 8, JPN6025039284, 2016, pages 333 - 50, ISSN: 0005697451 *

Also Published As

Publication number Publication date
CN116322644A (zh) 2023-06-23
EP4203974A1 (en) 2023-07-05
US20240000826A1 (en) 2024-01-04
CR20230135A (es) 2023-07-19
IL300805A (en) 2023-04-01
AU2021331487A1 (en) 2023-03-16
CO2023003656A2 (es) 2023-08-09
WO2022047249A1 (en) 2022-03-03
PE20231169A1 (es) 2023-07-26
EP4203974A4 (en) 2024-08-07
US20230091966A1 (en) 2023-03-23
JOP20230043A1 (ar) 2023-02-27
KR20230104119A (ko) 2023-07-07
CA3189915A1 (en) 2022-03-03
MX2023002418A (es) 2023-07-11

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