JP2023540599A - Cxcr4及びil-10を共発現する間葉系幹細胞並びにその使用 - Google Patents

Cxcr4及びil-10を共発現する間葉系幹細胞並びにその使用 Download PDF

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JP2023540599A
JP2023540599A JP2023515394A JP2023515394A JP2023540599A JP 2023540599 A JP2023540599 A JP 2023540599A JP 2023515394 A JP2023515394 A JP 2023515394A JP 2023515394 A JP2023515394 A JP 2023515394A JP 2023540599 A JP2023540599 A JP 2023540599A
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cxcr4
cells
expression cassette
human
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JP2023540599A5 (enExample
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ロザリオ エルバス-サルセド
ダミアン ガルシア-オルモ
マリアーノ ガルシア-アランス
ロドリゲス ミリアム エルナンド
ロンセロ フアン アントニオ ブエレン
ゴンサレス ロサ マリア ヤニェス
ガルシア マリア フェルナンデス
サンタラ メルセデス ロペス
フェレイラ マリーナ インマクラダ ガリン
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Centro de Investigación Biomédica en Red
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
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    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
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    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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JP2023515394A 2020-09-07 2021-09-07 Cxcr4及びil-10を共発現する間葉系幹細胞並びにその使用 Pending JP2023540599A (ja)

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JP2026011136A JP2026082892A (ja) 2020-09-07 2026-01-27 Cxcr4及びil-10を共発現する間葉系幹細胞並びにその使用

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EP20382792.8 2020-09-07
EP20382792.8A EP3964265A1 (en) 2020-09-07 2020-09-07 Mesenchymal stem cells co-expressing cxcr4 and il-10 and uses thereof
PCT/EP2021/074612 WO2022049306A1 (en) 2020-09-07 2021-09-07 Mesenchymal stem cells co-expressing cxcr4 and il-10 and uses thereof

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US (1) US20230398152A1 (enExample)
EP (2) EP3964265A1 (enExample)
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KR (1) KR20230082622A (enExample)
CN (1) CN116507733A (enExample)
AU (1) AU2021337798A1 (enExample)
BR (1) BR112023004167A2 (enExample)
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US12624086B2 (en) 2018-10-31 2026-05-12 Mayo Foundation For Medical Education And Research Materials and methods for treating cancer
US12264189B2 (en) 2018-10-31 2025-04-01 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
US12257286B2 (en) 2018-10-31 2025-03-25 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
CN115927178A (zh) * 2022-11-17 2023-04-07 华夏源(上海)生物科技有限公司 一种检测间充质干细胞抑制b细胞分化为浆细胞的方法

Citations (3)

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JP2001500369A (ja) * 1996-08-30 2001-01-16 ヒューマン ジノーム サイエンシーズ,インコーポレイテッド インターロイキン―19
JP2013526840A (ja) * 2009-12-21 2013-06-27 ファーマシーネ,インコーポレイテッド 組み換えブチリルコリンエステラーゼおよびその切断型
JP2019523001A (ja) * 2016-07-25 2019-08-22 ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ 改変されたナチュラルキラー細胞を生成する方法および使用方法

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CA2566267A1 (en) * 2005-12-09 2007-06-09 University Health Network Thymidylate kinase mutants and uses thereof
PL3242933T3 (pl) * 2015-01-08 2019-08-30 Apceth Gmbh & Co. Kg Zmodyfikowane genetycznie mezenchymalne komórki macierzyste wykazujące ekspresję alfa-1 antytrypsyny (aat)
JP7493497B2 (ja) * 2018-06-19 2024-05-31 フォンダッツィオーネ・テレソン・エティエッセ 操作された樹状細胞の生産及びその使用

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JP2013526840A (ja) * 2009-12-21 2013-06-27 ファーマシーネ,インコーポレイテッド 組み換えブチリルコリンエステラーゼおよびその切断型
JP2019523001A (ja) * 2016-07-25 2019-08-22 ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ 改変されたナチュラルキラー細胞を生成する方法および使用方法

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CA3194344A1 (en) 2022-03-10
SA523442866B1 (ar) 2024-05-05
US20230398152A1 (en) 2023-12-14
MX2023002741A (es) 2023-05-26
JP2026082892A (ja) 2026-05-19
WO2022049306A1 (en) 2022-03-10
KR20230082622A (ko) 2023-06-08
EP3964265A1 (en) 2022-03-09
AU2021337798A1 (en) 2023-05-18
EP4210834A1 (en) 2023-07-19
CN116507733A (zh) 2023-07-28
BR112023004167A2 (pt) 2023-05-09

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