JP2023532278A5 - - Google Patents

Info

Publication number
JP2023532278A5
JP2023532278A5 JP2022579946A JP2022579946A JP2023532278A5 JP 2023532278 A5 JP2023532278 A5 JP 2023532278A5 JP 2022579946 A JP2022579946 A JP 2022579946A JP 2022579946 A JP2022579946 A JP 2022579946A JP 2023532278 A5 JP2023532278 A5 JP 2023532278A5
Authority
JP
Japan
Prior art keywords
amino acid
sequence
seq
tcr
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022579946A
Other languages
English (en)
Japanese (ja)
Other versions
JP7781085B2 (ja
JP2023532278A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/039262 external-priority patent/WO2021263211A2/en
Publication of JP2023532278A publication Critical patent/JP2023532278A/ja
Publication of JP2023532278A5 publication Critical patent/JP2023532278A5/ja
Priority to JP2025136019A priority Critical patent/JP2025166212A/ja
Application granted granted Critical
Publication of JP7781085B2 publication Critical patent/JP7781085B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022579946A 2020-06-25 2021-06-25 抗原特異的t細胞受容体及びキメラ抗原受容体、並びにがん免疫療法のための免疫シグナル伝達モジュレーションにおける使用方法 Active JP7781085B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025136019A JP2025166212A (ja) 2020-06-25 2025-08-18 抗原特異的t細胞受容体及びキメラ抗原受容体、並びにがん免疫療法のための免疫シグナル伝達モジュレーションにおける使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063044150P 2020-06-25 2020-06-25
US63/044,150 2020-06-25
PCT/US2021/039262 WO2021263211A2 (en) 2020-06-25 2021-06-25 Antigen-specific t cell receptors and chimeric antigen receptors, and methods of use in immune signaling modulation for cancer immunotherapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025136019A Division JP2025166212A (ja) 2020-06-25 2025-08-18 抗原特異的t細胞受容体及びキメラ抗原受容体、並びにがん免疫療法のための免疫シグナル伝達モジュレーションにおける使用方法

Publications (3)

Publication Number Publication Date
JP2023532278A JP2023532278A (ja) 2023-07-27
JP2023532278A5 true JP2023532278A5 (https=) 2023-08-24
JP7781085B2 JP7781085B2 (ja) 2025-12-05

Family

ID=79281973

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022579946A Active JP7781085B2 (ja) 2020-06-25 2021-06-25 抗原特異的t細胞受容体及びキメラ抗原受容体、並びにがん免疫療法のための免疫シグナル伝達モジュレーションにおける使用方法
JP2025136019A Pending JP2025166212A (ja) 2020-06-25 2025-08-18 抗原特異的t細胞受容体及びキメラ抗原受容体、並びにがん免疫療法のための免疫シグナル伝達モジュレーションにおける使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025136019A Pending JP2025166212A (ja) 2020-06-25 2025-08-18 抗原特異的t細胞受容体及びキメラ抗原受容体、並びにがん免疫療法のための免疫シグナル伝達モジュレーションにおける使用方法

Country Status (7)

Country Link
US (1) US20230250149A1 (https=)
EP (1) EP4171587A4 (https=)
JP (2) JP7781085B2 (https=)
CN (1) CN116322750A (https=)
AU (1) AU2021297458A1 (https=)
CA (1) CA3188143A1 (https=)
WO (1) WO2021263211A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4519675A4 (en) * 2022-05-03 2026-04-08 3T Biosciences Inc T-LYMPHOCYTE TARGET DISCOVERY
KR20250017213A (ko) * 2022-05-25 2025-02-04 고쿠리츠 다이가쿠 호우징 도우카이 고쿠리츠 다이가쿠 기코우 폴리뉴클레오티드
WO2024163292A1 (en) * 2023-01-30 2024-08-08 Board Of Regents, The University Of Texas System T-cell receptors targeting her2 and methods of use thereof
EP4731758A2 (en) * 2023-06-20 2026-04-29 The Methodist Hospital Antigen-specific t cell receptors and chimeric antigen receptors, and methods of use in immune signaling modulation for cancer immunotherapy
WO2024263818A2 (en) * 2023-06-20 2024-12-26 Immunova Therapeutics Llc Synthetic t cell receptors for enhancing memory (stem) t cells using new transmembranes and signaling domains
WO2025084880A1 (ko) * 2023-10-20 2025-04-24 주식회사 이온셀 Ct83 항원에 결합하는 car-t 세포 및 이의 용도

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2899679C (en) * 2013-01-29 2023-03-21 Max-Delbruck-Centrum Fur Molekulare Medizin (Mdc) Berlin-Buch High avidity antigen recognizing constructs
CA3051222C (en) * 2013-06-10 2023-01-24 Dana-Farber Cancer Institute, Inc. Methods and compositions for reducing immunosupression by tumor cells
US10934346B2 (en) * 2014-02-14 2021-03-02 Bellicum Pharmaceuticals, Inc. Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12
HK1243631A1 (zh) 2014-10-27 2018-07-20 Fred Hutchinson Cancer Research Center 用於提高过继细胞免疫疗法效力的组合物和方法
US20170335331A1 (en) * 2014-10-31 2017-11-23 The Trustees Of The University Of Pennsylvania Altering Gene Expression in CART Cells and Uses Thereof
GB201509413D0 (en) 2015-06-01 2015-07-15 Ucl Business Plc Fusion protein
CA2996887A1 (en) * 2015-09-11 2017-03-16 Agenus Inc. Engineered host cells and methods of use thereof
JP2019515656A (ja) * 2016-03-15 2019-06-13 キャンサー・リサーチ・テクノロジー・リミテッドCancer Research Technology Limited キメラ抗原受容体
AU2019224051A1 (en) 2018-02-26 2020-09-03 Fred Hutchinson Cancer Center Compositions and methods for cellular immunotherapy
EP3806857A4 (en) * 2018-06-14 2022-03-02 2seventy bio, Inc. CD79A CHIMERIC ANTIGEN RECEPTORS
WO2020086647A1 (en) * 2018-10-23 2020-04-30 Regeneron Pharmaceuticals, Inc. Ny-eso-1 t cell receptors and methods of use thereof

Similar Documents

Publication Publication Date Title
JP2023532278A5 (https=)
JP7781243B2 (ja) ガイダンス及びナビゲーションコントロール蛋白質並びにその生産及び使用方法
KR102879284B1 (ko) 항-메소텔린 키메라 항원 수용체(car) 작제물 및 이의 용도
US11168150B2 (en) T cell receptor-like antibody agents specific for EBV latent membrane protein 2A peptide presented by human HLA
RU2757316C2 (ru) Новые моноклональные антитела к белку программируемой смерти 1(pd-1)
KR102048477B1 (ko) 프로그램화된 세포 사멸 단백질 리간드-1 (pd-l1)에 대한 항체 및 이의 용도
CN108610420B (zh) 抗cd19的人源化抗体以及靶向cd19的免疫效应细胞
AU2016305697B2 (en) Novel anti-PD-1 antibodies
JP6588534B2 (ja) 抗pd−1のモノクローナル抗体およびその獲得方法
NL2014935B1 (en) T cell receptor like antibodies having fine specificity.
US10618962B2 (en) Anti-CTLA4 antibodies
JP2022024054A (ja) 細胞傷害性tリンパ球関連タンパク質4(ctla-4)に対する新規モノクローナル抗体
JP2018529327A5 (https=)
KR20190105112A (ko) 사람 및 비-사람 cd3에 결합할 수 있는 cd3-결합 분자
CA3066779A1 (en) Anti-human papillomavirus (hpv) antigen-binding proteins and methods of use thereof
CN101541834A (zh) 癌症的预防和/或治疗剂
KR102048476B1 (ko) 프로그램화된 세포 사멸 단백질(pd-1)에 대한 신규 항체 및 이의 용도
JP2022542559A5 (https=)
JP2025156298A (ja) 抗ニューヨーク食道扁平上皮がん1(ny-eso-1)抗原結合タンパク質およびその使用方法
CN121248789A (zh) 制导和导航控制(gnc)抗体样蛋白及其制备和使用方法
JP2024526324A (ja) Bcma指向性細胞免疫療法の組成物および方法
CN108948194A (zh) 一种新的ctla-4单克隆抗体
JP2024105603A (ja) CARライブラリおよびscFvの製造方法
WO2021175681A1 (en) Novel non-immunogenic chimeric antigen receptors and uses thereof
CN119278213A (zh) 针对ctla-4的抗体及其使用方法