JP2023529485A5 - - Google Patents

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Publication number
JP2023529485A5
JP2023529485A5 JP2022576447A JP2022576447A JP2023529485A5 JP 2023529485 A5 JP2023529485 A5 JP 2023529485A5 JP 2022576447 A JP2022576447 A JP 2022576447A JP 2022576447 A JP2022576447 A JP 2022576447A JP 2023529485 A5 JP2023529485 A5 JP 2023529485A5
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JP
Japan
Prior art keywords
cancer
subject
combination according
combination
expression level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022576447A
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English (en)
Japanese (ja)
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JP2023529485A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/036992 external-priority patent/WO2021257398A1/en
Publication of JP2023529485A publication Critical patent/JP2023529485A/ja
Publication of JP2023529485A5 publication Critical patent/JP2023529485A5/ja
Pending legal-status Critical Current

Links

JP2022576447A 2020-06-14 2021-06-11 E-セレクチン標的化を介して微小環境媒介耐性を克服するための組成物および方法 Pending JP2023529485A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063038856P 2020-06-14 2020-06-14
US63/038,856 2020-06-14
US202063060605P 2020-08-03 2020-08-03
US63/060,605 2020-08-03
US202063198856P 2020-11-17 2020-11-17
US63/198,856 2020-11-17
PCT/US2021/036992 WO2021257398A1 (en) 2020-06-14 2021-06-11 Compositions and methods for overcoming microenvironment-mediated resistance via e-selectin targeting

Publications (2)

Publication Number Publication Date
JP2023529485A JP2023529485A (ja) 2023-07-10
JP2023529485A5 true JP2023529485A5 (enExample) 2024-06-06

Family

ID=76731129

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022576447A Pending JP2023529485A (ja) 2020-06-14 2021-06-11 E-セレクチン標的化を介して微小環境媒介耐性を克服するための組成物および方法

Country Status (12)

Country Link
US (1) US20230218649A1 (enExample)
EP (1) EP4164655A1 (enExample)
JP (1) JP2023529485A (enExample)
KR (1) KR20230024402A (enExample)
CN (1) CN116033907A (enExample)
AU (1) AU2021292458A1 (enExample)
BR (1) BR112022025480A2 (enExample)
CA (1) CA3181278A1 (enExample)
IL (1) IL298977A (enExample)
MX (1) MX2022015894A (enExample)
WO (1) WO2021257398A1 (enExample)
ZA (1) ZA202213322B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250100273A (ko) * 2023-12-26 2025-07-03 서울대학교병원 난소암 예방 또는 치료를 위한 데시타빈 및 벨로테칸의 병용 요법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2264043T3 (pl) 2005-09-02 2018-04-30 Glycomimetics, Inc. Heterobifunkcyjne inhibitory pan-selektyny
WO2009073911A1 (en) 2007-12-10 2009-06-18 Mater Medical Research Institute Treatment and prophylaxis
CA2760292A1 (en) 2009-05-01 2010-11-04 Glycomimetics, Inc. Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
KR102055958B1 (ko) * 2011-12-22 2019-12-13 글리코미메틱스, 인크. E-셀렉틴 길항제 화합물, 조성물, 및 이용 방법
WO2015048616A1 (en) * 2013-09-30 2015-04-02 Glycomimetics, Inc. Methods and compositions for treating and/or preventing mucositis
JP6689854B2 (ja) 2014-12-03 2020-04-28 グリコミメティクス, インコーポレイテッド E−セレクチンおよびcxcr4ケモカイン受容体のヘテロ二官能性阻害剤
US20200171005A9 (en) 2015-12-02 2020-06-04 Glycomimetics, Inc. Heterobifunctional Pan-Selectin Antagonists Having a Triazole Linker
AU2017341065B2 (en) 2016-10-07 2023-04-06 Crescent Biopharma, Inc. Highly potent multimeric E-selectin antagonists
JP7275131B2 (ja) * 2017-11-30 2023-05-17 グリコミメティクス, インコーポレイテッド 骨髄浸潤リンパ球を動員する方法、およびその使用
KR20200104889A (ko) 2017-12-29 2020-09-04 글리코미메틱스, 인크. E-셀렉틴 및 갈렉틴-3의 이종이기능성 억제제
KR20200128025A (ko) * 2018-03-05 2020-11-11 글리코미메틱스, 인크. 급성 골수성 백혈병 및 관련 병태의 치료 방법
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
WO2020219419A1 (en) 2019-04-24 2020-10-29 Glycomimetics, Inc. Multimeric pan–selectin antagonists
JP2022529806A (ja) 2019-04-24 2022-06-24 グリコミメティクス, インコーポレイテッド E-セレクチン、ガレクチン-3、および/またはcxcr4ケモカイン受容体のガラクトース連結型多量体糖模倣性阻害剤
US20220265691A1 (en) 2019-07-12 2022-08-25 Glycomimetics, Inc. Methods for use of gene expression as an indicator of e-selectin inhibitor efficacy and clinical outcome for multiple tumor types

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