JP2023526252A5 - - Google Patents
Info
- Publication number
- JP2023526252A5 JP2023526252A5 JP2022568800A JP2022568800A JP2023526252A5 JP 2023526252 A5 JP2023526252 A5 JP 2023526252A5 JP 2022568800 A JP2022568800 A JP 2022568800A JP 2022568800 A JP2022568800 A JP 2022568800A JP 2023526252 A5 JP2023526252 A5 JP 2023526252A5
- Authority
- JP
- Japan
- Prior art keywords
- hrd
- determining
- segments
- test
- scores
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063025126P | 2020-05-14 | 2020-05-14 | |
| US63/025,126 | 2020-05-14 | ||
| US202063041721P | 2020-06-19 | 2020-06-19 | |
| US63/041,721 | 2020-06-19 | ||
| PCT/US2021/032539 WO2021231921A1 (en) | 2020-05-14 | 2021-05-14 | Homologous recombination repair deficiency detection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023526252A JP2023526252A (ja) | 2023-06-21 |
| JP2023526252A5 true JP2023526252A5 (https=) | 2024-05-17 |
| JP7842700B2 JP7842700B2 (ja) | 2026-04-08 |
Family
ID=76250514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022568800A Active JP7842700B2 (ja) | 2020-05-14 | 2021-05-14 | 相同組換え修復欠損の検出 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US12241126B2 (https=) |
| EP (1) | EP4150113A1 (https=) |
| JP (1) | JP7842700B2 (https=) |
| WO (1) | WO2021231921A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3945525A1 (en) * | 2020-07-27 | 2022-02-02 | Sophia Genetics S.A. | Methods for identifying chromosomal spatial instability such as homologous repair deficiency in low coverage next-generation sequencing data |
| EP4377908A1 (en) * | 2021-07-28 | 2024-06-05 | Institut Curie | Prediction of brcaness/homologous recombination deficiency of breast tumors on digitalized slides |
| CN114400045B (zh) * | 2022-01-28 | 2024-09-20 | 元码基因科技(北京)股份有限公司 | 基于二代测序检测同源重组修复缺陷的方法、探针组、试剂盒和系统 |
| CN114694752B (zh) * | 2022-03-09 | 2023-03-10 | 至本医疗科技(上海)有限公司 | 预测同源重组修复缺陷的方法、计算设备和介质 |
| EP4496904A4 (en) * | 2022-03-23 | 2026-03-18 | Arima Genomics Inc | METHODS FOR SELECTING AND TREATMENT OF CANCER PATIENTS WHO ARE CANDIDATES FOR TREATMENT WITH PARP INHIBITORS |
| WO2024124181A2 (en) * | 2022-12-09 | 2024-06-13 | The Broad Institute, Inc. | Compositions and methods for detecting homologous recombination |
| EP4502183A1 (en) * | 2023-08-02 | 2025-02-05 | Fundació Privada Institut d'Investigació Oncològica de Vall Hebron | Method for determining the homologous recombination deficiency status of a tumor and for predicting the response of a cancer to a therapy |
| WO2025059338A1 (en) * | 2023-09-12 | 2025-03-20 | Guardant Health, Inc. | Methods for analyzing nucleic acids using sequence read family size distribution |
| WO2025213080A2 (en) * | 2024-04-04 | 2025-10-09 | Exai Bio Inc. | Systems and methods for detection of non-coding rnas |
| WO2025217185A1 (en) * | 2024-04-09 | 2025-10-16 | Foundation Medicine, Inc. | Parp inhibitors for the treatment of advanced prostate cancer |
| CN121188513B (zh) * | 2025-11-24 | 2026-03-17 | 崖州湾国家实验室 | 一种基于基因组扫描的小麦差异转座元件的检测方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582908B2 (en) | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| US20030017081A1 (en) | 1994-02-10 | 2003-01-23 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| DE69528706T2 (de) | 1994-08-19 | 2003-06-12 | Pe Corp. (Ny), Foster City | Gekoppeltes ampflikation- und ligationverfahren |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US6969488B2 (en) | 1998-05-22 | 2005-11-29 | Solexa, Inc. | System and apparatus for sequential processing of analytes |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| US7501245B2 (en) | 1999-06-28 | 2009-03-10 | Helicos Biosciences Corp. | Methods and apparatuses for analyzing polynucleotide sequences |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| AU7537200A (en) | 1999-09-29 | 2001-04-30 | Solexa Ltd. | Polynucleotide sequencing |
| ATE377093T1 (de) | 2000-07-07 | 2007-11-15 | Visigen Biotechnologies Inc | Sequenzbestimmung in echtzeit |
| WO2003046146A2 (en) | 2001-11-28 | 2003-06-05 | Applera Corporation | Compositions and methods of selective nucleic acid isolation |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| CA2579150C (en) | 2004-09-17 | 2014-11-25 | Pacific Biosciences Of California, Inc. | Apparatus and method for analysis of molecules |
| US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
| US7482120B2 (en) | 2005-01-28 | 2009-01-27 | Helicos Biosciences Corporation | Methods and compositions for improving fidelity in a nucleic acid synthesis reaction |
| US7282337B1 (en) | 2006-04-14 | 2007-10-16 | Helicos Biosciences Corporation | Methods for increasing accuracy of nucleic acid sequencing |
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| JP6117194B2 (ja) | 2011-06-17 | 2017-04-19 | ミリアド・ジェネティックス・インコーポレイテッド | アレル不均衡を評価するための方法および材料 |
| CN104781421B (zh) | 2012-09-04 | 2020-06-05 | 夸登特健康公司 | 检测稀有突变和拷贝数变异的系统和方法 |
| CN114574581A (zh) | 2013-03-15 | 2022-06-03 | 夸登特健康公司 | 检测稀有突变和拷贝数变异的系统和方法 |
| WO2015086473A1 (en) * | 2013-12-09 | 2015-06-18 | Institut Curie | Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors |
| CA2958801A1 (en) * | 2014-08-15 | 2016-02-18 | Myriad Genetics, Inc. | Methods and materials for assessing homologous recombination deficiency |
| WO2017062970A1 (en) | 2015-10-10 | 2017-04-13 | Guardant Health, Inc. | Methods and applications of gene fusion detection in cell-free dna analysis |
| MX2019007444A (es) | 2016-12-22 | 2019-08-16 | Guardant Health Inc | Metodos y sistemas para analisis de moleculas de acido nucleico. |
| EP3612643A4 (en) * | 2017-04-21 | 2020-12-23 | The University of British Columbia | CANCER STRATIFICATION AND PROGNOSIS |
| EP3625713A1 (en) | 2017-05-19 | 2020-03-25 | Guardant Health, Inc. | Methods and systems for detecting insertions and deletions |
| WO2020160414A1 (en) | 2019-01-31 | 2020-08-06 | Guardant Health, Inc. | Compositions and methods for isolating cell-free dna |
| WO2020176775A1 (en) | 2019-02-27 | 2020-09-03 | Guardant Health, Inc. | Computational modeling of loss of function based on allelic frequency |
| ES2989374T3 (es) * | 2019-12-10 | 2024-11-26 | Tempus Ai Inc | Sistemas y procedimientos para predecir el estado de deficiencia de recombinación homóloga de una muestra |
-
2021
- 2021-05-14 JP JP2022568800A patent/JP7842700B2/ja active Active
- 2021-05-14 EP EP21729776.1A patent/EP4150113A1/en active Pending
- 2021-05-14 US US17/320,976 patent/US12241126B2/en active Active
- 2021-05-14 WO PCT/US2021/032539 patent/WO2021231921A1/en not_active Ceased
-
2022
- 2022-06-28 US US17/809,516 patent/US12031186B2/en active Active
-
2024
- 2024-05-28 US US18/676,221 patent/US20250129426A1/en active Pending
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