JP2023521519A5 - - Google Patents
Info
- Publication number
- JP2023521519A5 JP2023521519A5 JP2023504152A JP2023504152A JP2023521519A5 JP 2023521519 A5 JP2023521519 A5 JP 2023521519A5 JP 2023504152 A JP2023504152 A JP 2023504152A JP 2023504152 A JP2023504152 A JP 2023504152A JP 2023521519 A5 JP2023521519 A5 JP 2023521519A5
- Authority
- JP
- Japan
- Prior art keywords
- immune cells
- population
- cells according
- ifnγ
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063005684P | 2020-04-06 | 2020-04-06 | |
| US63/005,684 | 2020-04-06 | ||
| PCT/US2021/025906 WO2021207150A1 (en) | 2020-04-06 | 2021-04-06 | Genetically modified immune cells expressing a chimeric antigen receptor and having reduced proinflammatory cytokine signaling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023521519A JP2023521519A (ja) | 2023-05-24 |
| JP2023521519A5 true JP2023521519A5 (https=) | 2024-04-12 |
Family
ID=78022619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023504152A Pending JP2023521519A (ja) | 2020-04-06 | 2021-04-06 | キメラ抗原受容体を発現し低減した炎症性サイトカインシグナル伝達を有する遺伝子改変された免疫細胞 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230149465A1 (https=) |
| EP (1) | EP4132973A4 (https=) |
| JP (1) | JP2023521519A (https=) |
| KR (1) | KR20230019419A (https=) |
| CN (1) | CN115698062A (https=) |
| AU (1) | AU2021251113A1 (https=) |
| CA (1) | CA3173490A1 (https=) |
| IL (1) | IL297034A (https=) |
| WO (1) | WO2021207150A1 (https=) |
| ZA (1) | ZA202210919B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114350665A (zh) * | 2022-01-19 | 2022-04-15 | 上海优替济生生物医药有限公司 | IFN-γ抑制剂及其用途 |
| US20230256065A1 (en) * | 2022-02-16 | 2023-08-17 | Elena RUSYN | Autologous stem cell vaccine and methods |
| EP4269432A1 (en) * | 2022-04-26 | 2023-11-01 | Universite de Rouen Normandie | Production of therapeutic antibodies by the microalgae phaeodactylum tricornutum |
| KR20250074841A (ko) * | 2023-11-20 | 2025-05-28 | (재) 스크립스코리아항체연구원 | 키메라 항원 수용체를 발현하는 면역 세포 및 트렙타비딘 스캐폴드 항체 유사 단백질을 포함하는 항암용 조성물, 및 이의 용도 |
| CN117965633A (zh) * | 2024-04-01 | 2024-05-03 | 北京双赢科创生物科技有限公司 | 一种IFNγ受体敲除的CAR-T细胞的制备方法与应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5574205A (en) * | 1989-07-25 | 1996-11-12 | Cell Genesys | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| HK1044159A1 (zh) * | 1998-12-01 | 2002-10-11 | 蛋白质设计实验室股份有限公司 | 抗γ-干扰素的人化抗体 |
| WO2004034988A2 (en) * | 2002-10-16 | 2004-04-29 | Amgen Inc. | Human anti-ifn-ϝ neutralizing antibodies as selective ifn-ϝ pathway inhibitors |
| US11091543B2 (en) * | 2015-05-07 | 2021-08-17 | Swedish Orphan Biovitrum Ag | Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications |
| MX2019004766A (es) * | 2016-10-24 | 2019-09-27 | Novimmune Sa | Metodos, composiciones y regimenes de dosificacion para tratar o prevenir indicaciones relacionadas con interferon-gamma. |
| US20200048618A1 (en) * | 2017-04-18 | 2020-02-13 | Autolus Limited | Cell |
| US12539308B2 (en) * | 2018-01-08 | 2026-02-03 | The Trustees Of The University Of Pennsylvania | Immune-enhancing RNAs for combination with chimeric antigen receptor therapy |
| SG11202007171PA (en) * | 2018-02-02 | 2020-08-28 | Univ Pennsylvania | Modified monocytes/macrophages/dendritic cells expressing chimeric antigen receptors and uses in diseases and disorders associated with protein aggregates |
| EP3802578A4 (en) * | 2018-06-01 | 2022-03-23 | Washington University | SUPPRESSION OF CYTOKINE RELEASE SYNDROME IN CHIMERIC ANTIGEN RECEPTOR CELL THERAPY |
| CN110615843B (zh) * | 2018-06-20 | 2023-05-09 | 上海隆耀生物科技有限公司 | 一种包含第三信号受体的嵌合抗原受体及其应用 |
| GB201814203D0 (en) * | 2018-08-31 | 2018-10-17 | King S College London | Engineered regulatory t cell |
-
2021
- 2021-04-06 WO PCT/US2021/025906 patent/WO2021207150A1/en not_active Ceased
- 2021-04-06 KR KR1020227038818A patent/KR20230019419A/ko active Pending
- 2021-04-06 EP EP21784804.3A patent/EP4132973A4/en not_active Withdrawn
- 2021-04-06 US US17/995,577 patent/US20230149465A1/en active Pending
- 2021-04-06 JP JP2023504152A patent/JP2023521519A/ja active Pending
- 2021-04-06 CN CN202180026149.5A patent/CN115698062A/zh active Pending
- 2021-04-06 AU AU2021251113A patent/AU2021251113A1/en not_active Abandoned
- 2021-04-06 IL IL297034A patent/IL297034A/en unknown
- 2021-04-06 CA CA3173490A patent/CA3173490A1/en active Pending
-
2022
- 2022-10-04 ZA ZA2022/10919A patent/ZA202210919B/en unknown