JP2023521162A - 重症急性呼吸器症候群を治療する方法 - Google Patents

重症急性呼吸器症候群を治療する方法 Download PDF

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Publication number
JP2023521162A
JP2023521162A JP2022561996A JP2022561996A JP2023521162A JP 2023521162 A JP2023521162 A JP 2023521162A JP 2022561996 A JP2022561996 A JP 2022561996A JP 2022561996 A JP2022561996 A JP 2022561996A JP 2023521162 A JP2023521162 A JP 2023521162A
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JP
Japan
Prior art keywords
dantrolene
administering
subject
sars
pharmaceutically acceptable
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Pending
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JP2022561996A
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English (en)
Japanese (ja)
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JP2023521162A5 (https=
Inventor
ヘプナー、エイドリアン
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イーグル ファーマスーティカルズ、インク．
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Publication of JP2023521162A publication Critical patent/JP2023521162A/ja
Publication of JP2023521162A5 publication Critical patent/JP2023521162A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2022561996A 2020-04-10 2021-04-08 重症急性呼吸器症候群を治療する方法 Pending JP2023521162A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063008529P 2020-04-10 2020-04-10
US63/008,529 2020-04-10
US202063062623P 2020-08-07 2020-08-07
US63/062,623 2020-08-07
PCT/US2021/026303 WO2021207444A1 (en) 2020-04-10 2021-04-08 Methods of treating severe acute respiratory syndrome

Publications (2)

Publication Number Publication Date
JP2023521162A true JP2023521162A (ja) 2023-05-23
JP2023521162A5 JP2023521162A5 (https=) 2024-04-11

Family

ID=75690705

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022561996A Pending JP2023521162A (ja) 2020-04-10 2021-04-08 重症急性呼吸器症候群を治療する方法

Country Status (11)

Country Link
US (1) US12582633B2 (https=)
EP (1) EP4132516A1 (https=)
JP (1) JP2023521162A (https=)
KR (1) KR20220167292A (https=)
CN (1) CN115916189A (https=)
AU (1) AU2021254415A1 (https=)
BR (1) BR112022020107A2 (https=)
CA (1) CA3174684A1 (https=)
IL (1) IL296518A (https=)
MX (1) MX2022012707A (https=)
WO (1) WO2021207444A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023521163A (ja) * 2020-04-10 2023-05-23 イーグル ファーマスーティカルズ、インク． Ｓａｒｓ－ｃｏｖ－２感染症を治療する方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019079721A1 (en) * 2017-10-20 2019-04-25 Eagle Pharmaceuticals, Inc. DANTROLENE PRODRUGS AND METHODS OF USE
WO2020112932A1 (en) * 2018-11-27 2020-06-04 Eagle Pharmaceuticals, Inc. Use of dantrolene and dantrolene prodrugs to treat radiation exposure
JP2023521163A (ja) * 2020-04-10 2023-05-23 イーグル ファーマスーティカルズ、インク． Ｓａｒｓ－ｃｏｖ－２感染症を治療する方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11123328B2 (en) 2017-11-14 2021-09-21 University Health Network Dantrolene and analogs thereof for the chronic treatment and prevention of dyssynchronous cardiac dysfunction
WO2019175761A1 (en) 2018-03-12 2019-09-19 Orbicular Pharmaceutical Technologies Private Limited Ready to use dantrolene compositions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019079721A1 (en) * 2017-10-20 2019-04-25 Eagle Pharmaceuticals, Inc. DANTROLENE PRODRUGS AND METHODS OF USE
WO2020112932A1 (en) * 2018-11-27 2020-06-04 Eagle Pharmaceuticals, Inc. Use of dantrolene and dantrolene prodrugs to treat radiation exposure
JP2023521163A (ja) * 2020-04-10 2023-05-23 イーグル ファーマスーティカルズ、インク． Ｓａｒｓ－ｃｏｖ－２感染症を治療する方法

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ANAESTHESIA, vol. 59, JPN6025013147, 2004, pages 364 - 373, ISSN: 0005727847 *
BIORXIV, JPN6025013148, 2019, pages 1 - 38, ISSN: 0005727848 *
BRAIN, BEHAVIOR, AND IMMUNITY, vol. 88, JPN6025013151, 18 May 2020 (2020-05-18), pages 28 - 29, ISSN: 0005727850 *
CHEMRXIV, JPN6025013152, 2020, pages 1 - 28, ISSN: 0005727851 *
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol. 24, JPN6025013150, October 2020 (2020-10-01), pages 10228 - 10238, ISSN: 0005727849 *
VIROLOGY, vol. 485, JPN6025013149, 2015, pages 330 - 339, ISSN: 0005727846 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023521163A (ja) * 2020-04-10 2023-05-23 イーグル ファーマスーティカルズ、インク． Ｓａｒｓ－ｃｏｖ－２感染症を治療する方法

Also Published As

Publication number Publication date
US12582633B2 (en) 2026-03-24
EP4132516A1 (en) 2023-02-15
WO2021207444A1 (en) 2021-10-14
CA3174684A1 (en) 2021-10-14
AU2021254415A1 (en) 2022-10-20
US20230149363A1 (en) 2023-05-18
IL296518A (en) 2022-11-01
CN115916189A (zh) 2023-04-04
BR112022020107A2 (pt) 2022-11-29
KR20220167292A (ko) 2022-12-20
MX2022012707A (es) 2023-01-05

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