JP2023520636A5 - - Google Patents
Info
- Publication number
- JP2023520636A5 JP2023520636A5 JP2022555860A JP2022555860A JP2023520636A5 JP 2023520636 A5 JP2023520636 A5 JP 2023520636A5 JP 2022555860 A JP2022555860 A JP 2022555860A JP 2022555860 A JP2022555860 A JP 2022555860A JP 2023520636 A5 JP2023520636 A5 JP 2023520636A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- chain variable
- variable region
- bispecific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062990281P | 2020-03-16 | 2020-03-16 | |
| US62/990,281 | 2020-03-16 | ||
| PCT/US2021/022626 WO2021188590A2 (en) | 2020-03-16 | 2021-03-16 | T-cell bispecific binding proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023520636A JP2023520636A (ja) | 2023-05-18 |
| JP2023520636A5 true JP2023520636A5 (https=) | 2024-03-21 |
Family
ID=77768281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022555860A Pending JP2023520636A (ja) | 2020-03-16 | 2021-03-16 | Ｔ細胞二重特異性結合タンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230183344A1 (https=) |
| EP (1) | EP4121462A4 (https=) |
| JP (1) | JP2023520636A (https=) |
| CN (1) | CN115667314A (https=) |
| AU (1) | AU2021239929A1 (https=) |
| CA (1) | CA3171709A1 (https=) |
| WO (1) | WO2021188590A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019265019B2 (en) | 2018-05-11 | 2025-11-06 | Beam Therapeutics Inc. | Methods of substituting pathogenic amino acids using programmable base editor systems |
| WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を治療するための方法 |
| WO2024040194A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
| EP4638505A1 (en) * | 2022-12-21 | 2025-10-29 | Erasmus University Rotterdam Medical Center | Bispecific antibodies targeting cd117 and cd3 |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| US20250127728A1 (en) | 2023-10-05 | 2025-04-24 | Capstan Therapeutics, Inc. | Constrained Ionizable Cationic Lipids and Lipid Nanoparticles |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
| CN119874942B (zh) * | 2025-03-28 | 2025-09-26 | 核欣(苏州)医药科技有限公司 | 一种放射性蛋白偶联药物及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL263466B2 (en) * | 2013-12-17 | 2023-10-01 | Genentech Inc | Anti-CD3 antibodies and methods of using them |
| DK3105252T3 (da) * | 2014-02-12 | 2019-10-14 | Michael Uhlin | Bispecifikke antistoffer til anvendelse ved stamcelletransplantation |
| HRP20201779T1 (hr) * | 2015-05-28 | 2021-01-22 | Genentech, Inc. | Stanični test za otkrivanje anti-cd3 homodimera |
| TWI796283B (zh) * | 2015-07-31 | 2023-03-21 | 德商安美基研究（慕尼黑）公司 | Ｍｓｌｎ及ｃｄ３抗體構築體 |
| AU2016337525B2 (en) * | 2015-10-16 | 2022-01-20 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for inhibition of lineage specific antigens |
| CN109073635A (zh) * | 2016-01-25 | 2018-12-21 | 豪夫迈·罗氏有限公司 | 用于测定t细胞依赖性双特异性抗体的方法 |
| US10538579B2 (en) * | 2016-08-15 | 2020-01-21 | Board Of Regents, The University Of Texas System | Bispecific pertussis antibodies |
| TWI687227B (zh) * | 2017-10-03 | 2020-03-11 | 生倍科技股份有限公司 | 用於t細胞免疫療法之組合及其用途 |
| WO2019084057A2 (en) * | 2017-10-24 | 2019-05-02 | Magenta Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR DEPLOYING CD117 + CELLS |
| WO2019084053A1 (en) * | 2017-10-24 | 2019-05-02 | Magenta Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR DEPLOYING CD117 + CELLS |
| KR20200069364A (ko) * | 2017-10-24 | 2020-06-16 | 마젠타 테라퓨틱스 인코포레이티드 | Cd117+ 세포의 고갈을 위한 조성물 및 방법 |
| AU2019366960A1 (en) * | 2018-10-23 | 2021-05-27 | Regeneron Pharmaceuticals, Inc. | Fc silenced antibody drug conjugates (ADCs) and uses thereof |
| GB201912681D0 (en) * | 2019-09-04 | 2019-10-16 | Eth Zuerich | Bispecific binding agent that binds to cd117/c-kit and cd3 |
-
2021
- 2021-03-16 AU AU2021239929A patent/AU2021239929A1/en not_active Abandoned
- 2021-03-16 US US17/906,471 patent/US20230183344A1/en active Pending
- 2021-03-16 EP EP21771456.7A patent/EP4121462A4/en active Pending
- 2021-03-16 CN CN202180035812.8A patent/CN115667314A/zh active Pending
- 2021-03-16 JP JP2022555860A patent/JP2023520636A/ja active Pending
- 2021-03-16 WO PCT/US2021/022626 patent/WO2021188590A2/en not_active Ceased
- 2021-03-16 CA CA3171709A patent/CA3171709A1/en active Pending
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