|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
JPS6147500A
(ja)
|
1984-08-15 |
1986-03-07 |
Res Dev Corp Of Japan |
キメラモノクロ−ナル抗体及びその製造法
|
|
EP0173494A3
(en)
|
1984-08-27 |
1987-11-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Chimeric receptors by dna splicing and expression
|
|
GB8422238D0
(en)
|
1984-09-03 |
1984-10-10 |
Neuberger M S |
Chimeric proteins
|
|
EP0436597B1
(en)
|
1988-09-02 |
1997-04-02 |
Protein Engineering Corporation |
Generation and selection of recombinant varied binding proteins
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
DK0585287T3
(da)
|
1990-07-10 |
2000-04-17 |
Cambridge Antibody Tech |
Fremgangsmåde til fremstilling af specifikke bindingsparelementer
|
|
CA2095633C
(en)
|
1990-12-03 |
2003-02-04 |
Lisa J. Garrard |
Enrichment method for variant proteins with altered binding properties
|
|
EP1820858B1
(en)
|
1991-03-01 |
2009-08-12 |
Dyax Corporation |
Chimeric protein comprising micro-protein having two or more disulfide bonds and embodiments thereof
|
|
ATE414768T1
(de)
|
1991-04-10 |
2008-12-15 |
Scripps Research Inst |
Bibliotheken heterodimerer rezeptoren mittels phagemiden
|
|
DE4122599C2
(de)
|
1991-07-08 |
1993-11-11 |
Deutsches Krebsforsch |
Phagemid zum Screenen von Antikörpern
|
|
US5786464C1
(en)
|
1994-09-19 |
2012-04-24 |
Gen Hospital Corp |
Overexpression of mammalian and viral proteins
|
|
NZ331688A
(en)
|
1996-03-28 |
2000-02-28 |
Univ Johns Hopkins |
Soluble divalent and multivalent heterodimeric analogs of proteins
|
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
KR100919593B1
(ko)
|
2000-06-29 |
2009-09-29 |
아보트 러보러터리즈 |
이중 특이성 항체 및 이의 제조 방법 및 이를 포함하는 조성물
|
|
BRPI0608376A8
(pt)
|
2005-04-22 |
2018-10-16 |
Lilly Co Eli |
composição de ligação, método de uso de uma composição de ligação, e, kit de detecção
|
|
PE20091163A1
(es)
|
2007-11-01 |
2009-08-09 |
Wyeth Corp |
Anticuerpos para gdf8
|
|
US20100260668A1
(en)
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
|
TW201006485A
(en)
|
2008-06-03 |
2010-02-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
AR081556A1
(es)
|
2010-06-03 |
2012-10-03 |
Glaxo Group Ltd |
Proteinas de union al antigeno humanizadas
|
|
DK2780368T3
(en)
|
2011-11-14 |
2018-02-05 |
Regeneron Pharma |
COMPOSITIONS AND PROCEDURES FOR INCREASING MUSCLE MASS AND MUSCLE STRENGTH BY SPECIFIC ANTAGONIZATION OF GDF8 AND / OR ACTIVIN A
|
|
US9518112B2
(en)
|
2012-03-08 |
2016-12-13 |
Ludwig Institute For Cancer Research Ltd |
TGF-β1 specific antibodies and methods and uses thereof
|
|
RS61778B1
(sr)
|
2013-05-06 |
2021-06-30 |
Scholar Rock Inc |
Kompozicije i postupci za modulaciju faktora rasta
|
|
ES2860952T3
(es)
|
2013-08-01 |
2021-10-05 |
Univ Catholique Louvain |
Proteína anti-garp y usos de la misma
|
|
WO2016089950A1
(en)
*
|
2014-12-04 |
2016-06-09 |
Beth Israel Deaconess Medical Center, Inc. |
Cancer therapy targeting intercellular adhesion molecule 4 (icam4)
|
|
UY36449A
(es)
|
2014-12-19 |
2016-07-29 |
Novartis Ag |
Composiciones y métodos para anticuerpos dirigidos a bmp6
|
|
WO2016115345A1
(en)
|
2015-01-14 |
2016-07-21 |
The Brigham And Women's Hospital, |
Treatment of cancer with anti-lap monoclonal antibodies
|
|
EP3770171A1
(en)
|
2015-04-03 |
2021-01-27 |
XOMA Technology Ltd. |
Treatment of cancer using inhibitors of tgf-beta and pd-1
|
|
WO2017023749A1
(en)
*
|
2015-07-31 |
2017-02-09 |
Tarveda Therapeutics, Inc. |
Compositions and methods for immunomodulation
|
|
HRP20211081T1
(hr)
|
2015-09-15 |
2021-10-15 |
Scholar Rock, Inc. |
Anti-pro/latentna miostatinska protutijela i njihove uporabe
|
|
CA3055555A1
(en)
*
|
2016-03-11 |
2017-09-14 |
Scholar Rock, Inc. |
Tgf.beta.1-binding immunoglobulins and use thereof
|
|
AU2017310027A1
(en)
|
2016-08-12 |
2019-01-31 |
Merck Patent Gmbh |
Combination therapy for cancer
|
|
TW201811827A
(zh)
|
2016-09-05 |
2018-04-01 |
日商中外製藥股份有限公司 |
抗TGF-β1抗體及使用方法
|
|
BR112019013908A2
(pt)
*
|
2017-01-06 |
2020-02-04 |
Scholar Rock, Inc. |
inibidores de tgfss1 isoforma-específicos, contexto-permissivos, e seus usos
|
|
WO2018129331A1
(en)
|
2017-01-07 |
2018-07-12 |
Merck Patent Gmbh |
Dosing regimens and dosage forms for targeted tgf-b inhibition
|
|
EP3571227A1
(en)
|
2017-01-20 |
2019-11-27 |
Sanofi |
Anti-tgf-beta antibodies and their use
|
|
AU2018228435C1
(en)
|
2017-03-02 |
2025-09-18 |
National Research Council Of Canada |
TGF-beta-receptor ectodomain fusion molecules and uses thereof
|
|
MA49690A
(fr)
|
2017-07-28 |
2021-05-19 |
Scholar Rock Inc |
Inhibiteurs spécifiques du complexe ltbp de tgf-bêta 1 et leurs utilisations
|
|
EP3694552A1
(en)
*
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
|
US20210340238A1
(en)
*
|
2018-07-11 |
2021-11-04 |
Scholar Rock, Inc. |
TGFß1 INHIBITORS AND USE THEREOF
|
|
MA53125A
(fr)
*
|
2018-07-11 |
2021-05-19 |
Scholar Rock Inc |
Inhibiteurs de tgf?1 sélectifs selon l'isoforme à affinité élevée
|
|
JP7654539B2
(ja)
|
2018-09-07 |
2025-04-01 |
ファイザー・インク |
抗αvβ8抗体、組成物及びその使用
|
|
CN113164766B
(zh)
|
2018-10-23 |
2025-02-25 |
供石公司 |
RGMc选择性抑制剂及其用途
|