JP2023504190A5 - - Google Patents
Info
- Publication number
- JP2023504190A5 JP2023504190A5 JP2022533105A JP2022533105A JP2023504190A5 JP 2023504190 A5 JP2023504190 A5 JP 2023504190A5 JP 2022533105 A JP2022533105 A JP 2022533105A JP 2022533105 A JP2022533105 A JP 2022533105A JP 2023504190 A5 JP2023504190 A5 JP 2023504190A5
- Authority
- JP
- Japan
- Prior art keywords
- lipid
- microparticles
- grna molecule
- lipid nanoparticles
- nanoparticles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962943093P | 2019-12-03 | 2019-12-03 | |
| US62/943,093 | 2019-12-03 | ||
| PCT/US2020/063150 WO2021113536A1 (en) | 2019-12-03 | 2020-12-03 | Systems and methods for lipid nanoparticle delivery of gene editing machinery |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023504190A JP2023504190A (ja) | 2023-02-01 |
| JP2023504190A5 true JP2023504190A5 (https=) | 2023-12-12 |
Family
ID=76222327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022533105A Pending JP2023504190A (ja) | 2019-12-03 | 2020-12-03 | 遺伝子編集機構の脂質ナノ粒子送達のためのシステムおよび方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230032846A1 (https=) |
| EP (1) | EP4069314A4 (https=) |
| JP (1) | JP2023504190A (https=) |
| AR (1) | AR122347A1 (https=) |
| WO (1) | WO2021113536A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013163628A2 (en) | 2012-04-27 | 2013-10-31 | Duke University | Genetic correction of mutated genes |
| US9828582B2 (en) | 2013-03-19 | 2017-11-28 | Duke University | Compositions and methods for the induction and tuning of gene expression |
| WO2016130600A2 (en) | 2015-02-09 | 2016-08-18 | Duke University | Compositions and methods for epigenome editing |
| WO2017035416A2 (en) | 2015-08-25 | 2017-03-02 | Duke University | Compositions and methods of improving specificity in genomic engineering using rna-guided endonucleases |
| EP4089175A1 (en) | 2015-10-13 | 2022-11-16 | Duke University | Genome engineering with type i crispr systems in eukaryotic cells |
| KR102787119B1 (ko) | 2015-11-30 | 2025-03-27 | 듀크 유니버시티 | 유전자 편집에 의한 인간 디스트로핀 유전자의 교정을 위한 치료용 표적 및 사용 방법 |
| US20190127713A1 (en) | 2016-04-13 | 2019-05-02 | Duke University | Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use |
| JP7490211B2 (ja) | 2016-07-19 | 2024-05-27 | デューク ユニバーシティ | Ｃｐｆ１に基づくゲノム編集の治療適用 |
| EP3740580A4 (en) | 2018-01-19 | 2021-10-20 | Duke University | GENOME ENGINEERING WITH CRISPR-CAS SYSTEMS IN EUKARYONTS |
| IL317874A (en) | 2022-06-24 | 2025-02-01 | Tune Therapeutics Inc | Compounds, systems and methods for reducing low density lipoproteins through targeted gene suppression |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014197748A2 (en) * | 2013-06-05 | 2014-12-11 | Duke University | Rna-guided gene editing and gene regulation |
| AU2016344609B2 (en) * | 2015-10-28 | 2022-05-12 | Vertex Pharmaceuticals Incorporated | Materials and methods for treatment of duchenne muscular dystrophy |
| JP7075597B2 (ja) * | 2016-05-05 | 2022-05-26 | デューク ユニバーシティ | デュシェンヌ型筋ジストロフィーを治療するためのｃｒｉｓｐｒ／ｃａｓ関連の方法および組成物 |
| EP3707155A2 (en) * | 2017-11-09 | 2020-09-16 | Vertex Pharmaceuticals Incorporated | Crispr/cas systems for treatment of dmd |
| AU2019216321A1 (en) * | 2018-01-31 | 2020-07-30 | The Board Of Regents Of The University Of Texas System | Compositions and methods for correcting dystrophin mutations in human cardiomyocytes |
-
2020
- 2020-12-03 EP EP20895944.5A patent/EP4069314A4/en active Pending
- 2020-12-03 JP JP2022533105A patent/JP2023504190A/ja active Pending
- 2020-12-03 AR ARP200103372A patent/AR122347A1/es unknown
- 2020-12-03 US US17/782,112 patent/US20230032846A1/en active Pending
- 2020-12-03 WO PCT/US2020/063150 patent/WO2021113536A1/en not_active Ceased
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