JP2023503504A - A consumable with two different aerosol-generating materials for a non-combustible aerosol delivery device - Google Patents

Abstract

The present invention provides consumables for use with non-combustion aerosol delivery devices. The consumable comprises a first aerosol-generating material and a second aerosol-generating material, each of the first and second aerosol-generating materials comprising an amorphous solid, the amorphous solid comprising: 0.5-60% by weight of a gelling agent, 0-80% by weight of an aerosol-forming material, and 0-60% by weight of at least one of an active agent, a flavorant and an acid, wherein: These weights are calculated on a dry weight basis and the amorphous solids of the first aerosol-generating material have a different composition than the amorphous solids of the second aerosol-generating material. [Selection figure] None

Description

Detailed description of the invention

[Technical field]
The present invention relates to consumables for use with non-combustion aerosol delivery devices. The consumable comprises an aerosol-generating material comprising amorphous solids.

[background]
Smoking consumables, such as cigarettes and cigars, burn tobacco during use to produce tobacco smoke. An alternative to these types of consumables releases an inhalable aerosol or vapor by releasing the compound from the substrate material by heating without burning. These are sometimes referred to as non-combustion smoking consumables or aerosol generating assemblies.

One example of such a product is a heating device that releases a compound by heating, but not burning, a solid aerosol-generating material. This solid aerosol-generating material may comprise tobacco material in some examples. Heating volatilizes at least one component of the material, typically forming an inhalable aerosol. These products are sometimes referred to as heat not burn devices, tobacco heating devices, or tobacco heating products. A variety of different arrangements are known for volatilizing at least one component of a solid aerosol-generating material.

Another example is hybrid devices. These comprise a liquid source (with or without nicotine) that is vaporized by heating to produce an inhalable vapor or aerosol. The device further comprises a solid aerosol-generating material (which may or may not comprise tobacco material), the components of which are entrained in the inhalable vapor or aerosol to produce the inhalant medium.

[overview]
The present invention provides consumables for use with non-combustion aerosol delivery devices. This consumable is
a first aerosol-generating material;
a second aerosol-generating material;
wherein each of the first and second aerosol-generating materials comprises an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol forming agent;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein the weights are calculated on a dry weight basis and the amorphous solids of the first aerosol-generating material have a different composition than the composition of the amorphous solids of the second aerosol-generating material.

The present invention also provides methods of manufacturing consumables for use with non-combustion aerosol delivery devices. This method
providing a support;
depositing on a support at least two separate portions of a slurry comprising a gelling agent, an aerosol-forming material, and at least one of an active agent, a flavorant and an acid;
drying at least two separate portions of the slurry to obtain a first aerosol-generating material and a second aerosol-generating material, the first and second aerosol-generating materials attached to a support; there is a step and
forming a consumable;
wherein each of the first and second aerosol-generating materials comprises an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein the weights are calculated on a dry weight basis and the amorphous solids of the first aerosol-generating material have a different composition than the composition of the amorphous solids of the second aerosol-generating material.

In a further aspect of the invention, a non-combustion aerosol delivery system is provided comprising a consumable of the invention and a non-combustion aerosol delivery device. The non-combustion aerosol delivery device comprises an aerosol generating device arranged to generate an aerosol from the consumable when the consumable is used with the non-combustion aerosol delivery device.

The present invention also relates to the use of the consumables described herein in non-combustion aerosol delivery devices. The device is arranged to generate an aerosol from the consumable when the consumable is used with the non-combustion aerosol delivery device.

Further features and advantages of the invention will become apparent from the following description of preferred embodiments of the invention. Here, these descriptions are provided only by way of illustration with reference to the accompanying drawings.

FIG. 2 is a cross-sectional view of an example of a consumable; 2 is a perspective view of the consumable of FIG. 1; FIG. 1 is a cross-sectional elevational view of an example consumable; FIG. 4 is a perspective view of the consumable of FIG. 3; FIG. 1 is a perspective view of an example non-combustion aerosol delivery system; FIG. 1 is a cross-sectional view of an example non-combustion aerosol delivery system; FIG. 1 is a perspective view of an example non-combustion aerosol delivery system; FIG.

[Detailed description]
As discussed above, one aspect of the invention provides consumables for use with non-combustion aerosol delivery devices. This consumable is
a first aerosol-generating material;
a second aerosol-generating material;
wherein each of the first and second aerosol-generating materials comprises an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein the weights are calculated on a dry weight basis and the amorphous solids of the first aerosol-generating material have a different composition than the composition of the amorphous solids of the second aerosol-generating material.

In this aspect of the invention, the weight percentage of at least one active agent, flavorant and acid represents the combined total weight of any combination of active agent, flavorant and acid described herein.

In one embodiment, the amorphous solid of the first aerosol-generating material comprises the active agent and the amorphous solid of the second aerosol-generating material comprises the flavorant. In certain such examples, the amorphous solids of the first aerosol-generating material are free of flavorants and acids. In some embodiments, the amorphous solid of the first aerosol-generating material does not comprise the flavorants contained in the second aerosol-generating material and does not comprise acids. In other embodiments, the amorphous solids of the first aerosol-generating material also comprise flavorants and/or acids. In some examples, the amorphous solid of the second aerosol-generating material is free of active agents and acids. In some embodiments, the amorphous solid of the second aerosol-generating material does not comprise an active agent contained in the first aerosol-generating material and does not comprise an acid. In an alternative embodiment, the amorphous solid of the second aerosol-generating material also comprises an active substance and/or an acid.

In these embodiments, the amorphous solid of the first aerosol-generating material comprising the active agent comprises
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
0.1 to 60% by weight of at least one active substance;
, where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the first aerosol-generating material may have the following composition expressed as a percentage of the total dry weight, i.e., on a dry weight basis (all calculated on a dry weight basis): about 10% to about 70% by weight, i. or from about 20% to about 60%, or from about 25% to about 40% by weight of aerosol-forming material (all calculated on a dry weight basis), from about 0.5% to about 50%, or about 1 wt% to 40 wt%, or from about 2 wt% to about 30 wt%, or from about 5 wt% to about 20 wt%, or from about 2 wt% to about 10 wt% active agent. may Suitably, the amorphous solid of the first aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 30% to about 60% by weight; an agent, an aerosol-forming material in an amount of about 20% to about 60% by weight, and an active agent in an amount of about 0.1% to about 10% by weight. In some of these embodiments, the amorphous solids of the first aerosol-generating material are free of flavorants and acids contained in the second aerosol-generating material. In alternative embodiments, the amorphous solids of the first aerosol-generating material also comprise flavorants and/or acids.

In this embodiment, the amorphous solid of the second aerosol-generating material comprising the flavorant comprises:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
5-60% by weight of a flavoring agent;
, where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the second aerosol-generating material may have the following composition (all calculated on a dry weight basis): from about 5% to about 40% by weight, or about 10% to 30% by weight, or about 15% to about 25% by weight of gellant, about 10% to about 70% by weight, or about 20% to about 60% by weight, or about 25% by weight % to about 40% by weight (all calculated on a dry weight basis), about 10% to about 50% by weight, or about 20% to about 40% by weight, or about 25% to about 30% by weight. It may have a composition of flavorings in the amount of % by weight. Suitably, the amorphous solid of the second aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 30% to about 60% by weight; aerosol-forming material in an amount from about 10% to about 40% by weight; and a flavoring agent in an amount from about 20% to about 50% by weight. In some embodiments, the amorphous solid of the second aerosol-generating material does not include the active agent contained in the amorphous solid of the first aerosol-generating material, and the acid. In some embodiments, the amorphous solid of the second aerosol-generating material also comprises an active agent and/or an acid.

In a further embodiment, the amorphous solid of the first aerosol-generating material comprises the active agent and the amorphous solid of the second aerosol-generating material comprises the acid. In certain such embodiments, the amorphous solids of the first aerosol-generating material are free of flavorants and acids. In some embodiments, the amorphous solid of the first aerosol-generating material does not comprise the acid contained in the second aerosol-generating material and does not comprise a flavorant. In other embodiments, the amorphous solids of the first aerosol-generating material also comprise acids and/or flavorants. In certain such embodiments, the amorphous solids of the second aerosol-generating material are free of active agents and flavorants. In some embodiments, the amorphous solid of the second aerosol-generating material does not comprise an active substance contained in the first aerosol-generating material and does not comprise a flavorant. In other embodiments, the amorphous solids of the second aerosol-generating material also comprise active agents and/or flavorants.

In this embodiment, the amorphous solid of the first aerosol-generating material comprising the active substance comprises
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
0.1 to 60% by weight of at least one active substance;
, where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the first aerosol-generating material may have the following composition (all calculated on a dry weight basis): about 5% to about 40% by weight, or about 10% to 30%, or from about 15% to about 25% by weight of gelling agent, from about 10% to about 50%, or from about 20% to about 40%, or about 25% by weight % to about 35% by weight (all calculated on a dry weight basis), from about 1% to about 50% by weight, or from about 2% to about 40% by weight, or from about 5% to about 30% by weight. It may have a composition of actives in the amount of % by weight. Suitably, the amorphous solid of the first aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 30% to about 60% by weight; an agent, an aerosol-forming material in an amount of about 20% to about 60% by weight, and an active agent in an amount of about 0.1% to about 10% by weight. In some embodiments, the amorphous solids of the first aerosol-generating material are free of acids and flavorants. In alternative embodiments, the amorphous solids of the first aerosol-generating material also comprise flavorants and/or acids.

In this embodiment, the amorphous solid of the second aerosol-generating material comprising acid comprises
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
0.1 to 10% by weight of acid;
, where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the second aerosol-generating material may have the following composition (calculated on a dry weight basis): about 5% to about 40% by weight, or about 10% by weight. % to 30% by weight, or from about 15% to about 25% by weight of gelling agent, from about 10% to about 50% by weight, or from about 20% to about 40% by weight, or about 25% by weight. aerosol-forming material in an amount of to about 35% by weight (all calculated on a dry weight basis), from about 0.1% to about 8%, or from about 0.5% to about 7%, or about 1% by weight; It may have a composition of acid in an amount of to about 5% by weight, or from about 1% to about 3% by weight. Suitably, the amorphous solid of the second aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 40% to about 70% by weight; an agent, an aerosol-forming material in an amount from about 20% to about 50% by weight, and an acid in an amount from about 0.1% to about 5% by weight. In some embodiments, the amorphous solids of the second aerosol-generating material are free of active agents and flavorants. In an alternative embodiment, the amorphous solid of the second aerosol-generating material also comprises an active agent and/or flavorant.

In still further embodiments, the amorphous solid of the first aerosol-generating material comprises a flavorant and the amorphous solid of the second aerosol-generating material comprises an acid. In certain such embodiments, the amorphous solid of the first aerosol-generating material is free of acids and active agents. In some embodiments, the amorphous solid of the first aerosol-generating material does not comprise the acid contained in the second aerosol-generating material and does not comprise an active substance. In other embodiments, the amorphous solid of the first aerosol-generating material also comprises an acid and/or an active agent. In certain embodiments, the amorphous solids of the second aerosol-generating material are free of flavorants and actives. In some embodiments, the amorphous solid of the second aerosol-generating material does not comprise the flavorants contained in the first aerosol-generating material and does not comprise an active agent. In other embodiments, the amorphous solids of the second aerosol-generating material also comprise flavorants and/or active agents.

In this embodiment, the amorphous solid of the flavorant-comprising first aerosol-generating material comprises:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
5-60% by weight of a flavoring agent;
, where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the first aerosol-generating material may have the following composition (all calculated on a dry weight basis): about 5% to about 40% by weight, or about 10% to 30%, or from about 15% to about 25% by weight of gelling agent, from about 10% to about 50%, or from about 20% to about 40%, or about 25% by weight % to about 35% by weight (all calculated on a dry weight basis), about 30% to about 60% by weight, or about 40% to about 55% by weight, or about 45% to about 50% by weight. It may have a composition of flavorings in the amount of % by weight. Suitably, the amorphous solid of the first aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 30% to about 60% by weight; aerosol-forming material in an amount from about 10% to about 40% by weight; and a flavoring agent in an amount from about 10% to about 50% by weight. In some embodiments, the amorphous solid of the first aerosol-generating material is free of acids and active agents. In an alternative embodiment, the amorphous solid of the first aerosol-generating material also comprises an acid and/or an active substance.

In this embodiment, the amorphous solid of the second aerosol-generating material comprising acid comprises
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
0.1 to 10% by weight of acid;
, where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the second aerosol-generating material may have the following composition (all calculated on a dry weight basis): from about 5% to about 40% by weight, or about 10% to 30%, or from about 15% to about 25% by weight of gelling agent, from about 10% to about 50%, or from about 20% to about 40%, or about 25% by weight % to about 35% by weight (all calculated on a dry weight basis), about 0.1% to about 8% by weight, or about 0.5% to about 7% by weight, or about 1% by weight. % to about 5% by weight, or from about 1% to about 3% by weight of the acid. Suitably, the amorphous solid of the second aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 40% to about 70% by weight; an agent, an aerosol-forming material in an amount from about 20% to about 50% by weight, and an acid in an amount from about 0.1% to about 5% by weight. In some embodiments, the amorphous solids of the second aerosol-generating material do not contain active agents or flavorants. In an alternative embodiment, the amorphous solid of the second aerosol-generating material also comprises an active agent and/or flavorant.

In a further embodiment, the amorphous solid of one of the first or second aerosol-generating materials is free of actives, flavorants and acids. In some embodiments, the amorphous solids of the first aerosol-generating material do not comprise active agents, flavorants, or acids. In this embodiment, an aerosol-forming material free of actives, flavorants and acids is provided for the purpose of providing a source of aerosol-forming material, eg, a moisturizer. Thus, in this embodiment, the amorphous solids of the active agent, flavorant and acid-free aerosol-generating material is at least 5% by weight, such as from about 10% to about 50%, or from about 20% to about 20% by weight. The aerosol-forming material is provided in an amount of about 40% by weight, or from about 25% to about 35% by weight (all calculated on a dry weight basis). In an exemplary embodiment, the first aerosol-generating material comprises
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
and is free of actives, flavors and acids,
the second aerosol-generating material comprises 0.1-60% by weight of at least one of an active agent, a flavorant and an acid;
Here, these weights are calculated on a dry weight basis.

In some such embodiments, the consumables of the present invention comprise such primary aerosol-generating materials in combination with any other secondary aerosol-generating materials described herein.

In some embodiments, both the amorphous solids of the first and second aerosol-generating materials comprise active agents. In some such embodiments, the amorphous solids of the first and second aerosol-generating materials comprise the same active agent. In some such embodiments, the active agent is present in different amounts. As used herein, "amount" means that the amorphous solids comprise 0% active material, in other words, the amorphous solids of the first or second aerosol-generating material equals the amount of the other aerosol-generating material. It can mean free of active substances present in the amorphous solid of the material.

In some embodiments, both the amorphous solids of the first and second aerosol-generating materials comprise active agents. In some such embodiments, the amorphous solids of the first and second aerosol-generating materials comprise the same active substance, wherein the amorphous solid of the first aerosol-generating material comprises the second The amount of active agent is greater than the amount of active agent present in the amorphous solid of the aerosol-generating material. In some embodiments, the amorphous solids of the first and second aerosol-generating materials comprise the same active agent, wherein the amorphous solid of the first aerosol-generating material comprises the amorphous solid of the second aerosol-generating material. It comprises an amount of active substance that is less than the amount of active substance present in the amorphous solid of the material.

In some such embodiments, the amorphous solids of the first and second aerosol-generating materials comprise an amount of active agent greater than 0.1% (all calculated on a dry weight basis), e.g. Both the amorphous solids of the first and second aerosol-generating materials comprise at least 0.2, 0.5, 1.0, 1.5, or 2% active agent. In an exemplary embodiment, the amorphous solid of the first aerosol-generating material comprises 0-30% by weight of the active substance present therein, and the amorphous solid of the second aerosol-generating material comprises with 31-60% by weight of active material present in the Suitably, the amorphous solid of the first aerosol-generating material comprises 0-20% by weight of active substance present therein (eg 1-15% by weight or 5-10% by weight) and the second The amorphous solid of the aerosol-generating material of has 30-60% by weight of active agent present therein (eg, 30-50% or 40-60% by weight). In some such embodiments, the amorphous solid of the first aerosol-generating material comprises the same active agent present in the amorphous solid of the second aerosol-generating material. In some such embodiments, the amorphous solid of the first aerosol-generating material comprises an active agent that is different from the active agent present in the amorphous solid of the second aerosol-generating material.

In such embodiments, the two aerosol-generating materials may comprise substantially the same ingredients, except that the amount of active agent present in each of the two aerosol-generating materials is different. In a non-limiting example, a consumable according to the invention comprises:
a first aerosol-generating material;
a second aerosol-generating material;
wherein the first aerosol-generating material comprises an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-5% by weight of active substance, wherein these weights are calculated on a dry weight basis, and the second aerosol-generating material comprises an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
5-10% by weight of active material, where these weights are calculated on a dry weight basis. Suitably, the amorphous solid of the first aerosol-generating material comprises from 0.1 to 2% by weight of active substance contained therein and the amorphous solid of the second aerosol-generating material comprises with 2-10% by weight of active material contained in the Preferably the active substance is nicotine.

In such embodiments, the first and second aerosol-generating materials may further comprise variable amounts of flavorants and/or acids. In other embodiments, the first and/or second aerosol-generating materials are free of flavorants and/or acids.

In the above embodiment, preferably the active substance is nicotine and the amorphous solids of the first aerosol-generating material is 0.1-5 wt% nicotine, such as 0.5-4 wt%, 1 ~3 wt%, or 2-5 wt% nicotine, wherein the amorphous solid of the second aerosol-generating material comprises 5-10 wt% nicotine, such as 6-9 wt%, or 7-8 wt% % nicotine, where these weights are calculated on a dry weight basis and the amorphous solids of the first aerosol-generating material are nicotine contained in the amorphous solids of the second aerosol-generating material with an amount of nicotine different from the amount of

In some embodiments, the amorphous solid of the first aerosol-generating material comprises an active agent that is different from the active agent present in the amorphous solid of the second aerosol-generating material.

In some embodiments, the amorphous solid of the first aerosol-generating material comprises a different flavorant than the flavorant present in the amorphous solid of the second aerosol-generating material.

In some examples, the amorphous solids of at least one aerosol-generating material referred to above comprise two or more of flavorants, active agents and/or acids. For example, in some embodiments, the amorphous solids of the first and/or second aerosol-generating material comprise flavorants and actives, but no acid. In other examples, the amorphous solids of the first and/or second aerosol-generating material comprise acid and active substance, but no flavorant. In other examples, the amorphous solids of the first and/or second aerosol-generating material comprise flavorant and acid, but no active agent.

It is also envisioned that the consumables of the present invention comprise aerosol-generating materials as discussed above with different types of flavorants. In such embodiments, the amorphous solids of the first aerosol-generating material comprise a different flavorant than the flavorant contained in the amorphous solids of the second aerosol-generating material. In such embodiments, the two aerosol-generating materials (e.g., first and second aerosol-generating materials) are such that the amorphous solid of the first aerosol-generating material is the amorphous solid of the second aerosol-generating material. It may comprise substantially the same ingredients except that it comprises a different flavorant than that present in the solid. In a non-limiting example, the amorphous solids of the two aerosol-generating materials comprise an active agent, an acid, and a flavorant, where the flavorant in the amorphous solid of the first aerosol-generating material is the It differs from the flavorant in the amorphous solid of the aerosol-generating material. In some embodiments, the consumables of the present invention may comprise more than two aerosol-generating materials, wherein the amorphous solid of each aerosol-generating material comprises a separate A flavorant is provided that is different from the flavorant present in the at least one other amorphous solid of the aerosol-generating material.

It is also envisioned that the aerosol-generating materials in the consumables of the present invention differ from each other in type of active agent. In such embodiments, the amorphous solids of the two aerosol-generating materials may comprise substantially the same components, except that the active substance present in the amorphous solids is different. In one embodiment, the amorphous solid of the first aerosol-generating material comprises an active agent that is different from the active agent present in the amorphous solid of the second aerosol-generating material. In some embodiments, the consumables of the present invention comprise three or more aerosol-generating materials, and the amorphous solid of each aerosol-generating material is the amorphous solid of at least one other aerosol-generating material in the consumable. It comprises an active substance different from that present in the solid.

It is also envisioned that the aerosol-generating materials in the consumables of the present invention will differ from each other in the amount of flavorant or acid. In some embodiments, the flavorant in the amorphous solids of the first aerosol-generating material is present in a different amount than the flavorant in the amorphous solids of the second aerosol-generating material. For example, the amount of flavorant present in the amorphous solids of the first aerosol-generating material is greater than the amount of flavorant present in the second aerosol-generating material. In some such embodiments, the acid in the amorphous solids of the first aerosol-generating material is present in an amount that differs from the amount of acid in the amorphous solids of the second aerosol-generating material. For example, the amount of acid present in the amorphous solid of the first aerosol-generating material is greater than the amount of acid present in the second aerosol-generating material.

It will be appreciated that there are numerous combinations of aerosol-generating materials that can be included in the consumables of the present invention. All combinations of actives, flavorants and acids are included within the scope of the invention.

In some embodiments, the consumable comprises a third aerosol-generating material comprising amorphous solids. This amorphous solid is
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein these weights are calculated on a dry weight basis and the amorphous solid of the third aerosol-generating material is the amorphous solid of the first aerosol-generating material and/or the second aerosol-generating material has a composition different from that of

In some embodiments, the consumable comprises a fourth aerosol-generating material comprising an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein the weights are calculated on a dry weight basis and the amorphous solids of the fourth aerosol-generating material are non-crystalline solids of at least one of the first, second, or third aerosol-generating materials It has a composition different from that of a crystalline solid.

In some embodiments, the consumable comprises 5 or more aerosol-generating materials having the characteristics described above. Preferably, the amorphous solids of each further aerosol-generating material have a composition different from the composition of the amorphous solids of at least one other aerosol-generating material included in the consumable. Indeed, in some embodiments, the consumable comprises 5, 6, 7, 8, 9 or 10 aerosol-generating materials, each of which contains at least one other an amorphous solid having a different composition than the amorphous solid of the aerosol-generating material of . In such embodiments, each of the additional aerosol-generating materials comprises an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein the weights are calculated on a dry weight basis and the amorphous solid of the fifth, sixth, seventh, eighth, ninth, or tenth aerosol-generating material is included in the consumable has a different composition than the amorphous solid of at least one other aerosol-generating material used.

In some examples, the amorphous solid of each aerosol-generating material comprises one of a flavorant, an acid, an active agent, or is free of a flavorant, an acid and an active agent and is subjected to aerosolization. Sometimes contributes only to moisturizing.

In a non-limiting exemplary embodiment, a consumable according to the present invention comprises:
a first aerosol-generating material;
a second aerosol-generating material;
a third aerosol-generating material;
a fourth aerosol-generating material;
and each of the first through fourth aerosol-generating materials comprises an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol forming agent;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein these weights are calculated on a dry weight basis and the amorphous solids of the first aerosol-generating material are free of actives, flavorants and acids;
the amorphous solid of the second aerosol-generating material comprises a flavorant but is free of actives and acids;
the amorphous solid of the third aerosol-generating material comprises an active substance but is free of flavorants and acids;
The amorphous solid of the fourth aerosol-generating material comprises acid, but no active agent and flavorant.

In this embodiment, the amorphous solid of the first aerosol-generating material, which is free of flavorants, actives and acids, comprises:
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the first aerosol-generating material may have the following composition (all calculated on a dry weight basis): about 5% to about 40% by weight, or about 10% to 30%, or from about 15% to about 25% by weight of gelling agent, from about 10% to about 50%, or from about 20% to about 40%, or about 25% by weight % to about 35% by weight of aerosol-forming material (all calculated on a dry weight basis).

In this embodiment, the amorphous solid of the second aerosol-generating material comprising a flavorant but no active agent and no acid comprises:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
5-60% by weight of a flavoring agent;
where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the second aerosol-generating material may have the following composition (all calculated on a dry weight basis): from about 5% to about 40% by weight, or about 10% to 30%, or from about 15% to about 25% by weight of gelling agent, from about 10% to about 50%, or from about 20% to about 40%, or about 25% by weight % to about 35% by weight (all calculated on a dry weight basis), about 30% to about 60% by weight, or about 40% to about 55% by weight, or about 45% to about 50% by weight. It may have a composition of flavorings in the amount of % by weight. Suitably, the amorphous solid of the second aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 30% to about 60% by weight; aerosol-forming material in an amount from about 10% to about 40% by weight; and a flavoring agent in an amount from about 10% to about 50% by weight.

In this embodiment, the amorphous solid of the third aerosol-generating material comprising the active agent but no flavorant and no acid is
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
5-60% by weight of at least one active substance;
, where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the third aerosol-generating material may have the following composition (all calculated on a dry weight basis): about 5% to about 40% by weight, or about 10% to 30%, or from about 15% to about 25% by weight of gelling agent, from about 10% to about 50%, or from about 20% to about 40%, or about 25% by weight % to about 35% by weight of the aerosol-forming material (all calculated on a dry weight basis), about 30% to about 60% by weight, or about 40% to 55% by weight, or about 45% to about 50% by weight. It may have a composition of % amount of active material. Suitably, the amorphous solid of the first aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 30% to about 60% by weight; an agent, an aerosol-forming material in an amount of about 20% to about 60% by weight, and an active agent in an amount of about 0.1% to about 10% by weight.

In this embodiment, the amorphous solid of the fourth aerosol-generating material comprising acid but no active agent and no flavorant is
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
0.1 to 10% by weight of acid, where these weights are calculated on a dry weight basis.

In this embodiment, the amorphous solids of the fourth aerosol-generating material may have the following composition (all calculated on a dry weight basis): about 5% to about 40% by weight, or about 10% to 30%, or from about 15% to about 25% by weight of gelling agent, from about 10% to about 50%, or from about 20% to about 40%, or about 25% by weight % to about 35% by weight (all calculated on a dry weight basis), about 0.1% to about 8% by weight, or about 0.5% to about 7% by weight, or about 1% by weight. % to about 5% by weight, or from about 1% to about 3% by weight of the acid. Suitably, the amorphous solid of the fourth aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 40% to about 70% by weight; an agent, an aerosol-forming material in an amount from about 20% to about 50% by weight, and an acid in an amount from about 0.1% to about 5% by weight.

Formulations The following formulations represent exemplary component amounts of each excipient in the aerosol-generating material included in the consumables of the present invention.

In embodiments in which the amorphous solid of the aerosol-generating material in the consumable comprises an active agent, in some such embodiments, the amorphous solid comprises:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0.1 to 60% by weight of at least one active substance;
, where these weights are calculated on a dry weight basis.

In these embodiments, the amorphous solids of the aerosol-generating material may have the following composition (all calculated on a dry weight basis): from about 5 wt% to about 40 wt%, or about 10 wt% % to 30% by weight, or from about 15% to about 25% by weight, from about 10% to about 70% by weight, or from about 20% to about 60% by weight, or from about 25% by weight. aerosol-forming material in an amount of about 40% by weight (all calculated on a dry weight basis), from about 0.5% to about 50% by weight, or from about 1% to 40% by weight, or from about 2% to about 30% by weight; %, or from about 5% to about 20%, or from about 2% to about 10% by weight of active material. Suitably, the amorphous solid of the aerosol-generating material may have the following composition (all calculated on a dry weight basis): gelling agent in an amount of about 30% to about 60% by weight; It may have a composition of aerosol-forming material in an amount of about 20% to about 60% by weight and an active agent in an amount of about 0.1% to about 10% by weight.

In embodiments in which the amorphous solid of the aerosol-generating material in the consumable comprises a flavorant, in some such embodiments, the amorphous solid comprises:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
5-60% by weight of a flavoring agent;
, where these weights are calculated on a dry weight basis.

In these embodiments, the amorphous solids of the aerosol-generating material may have the following composition (all calculated on a dry weight basis): from about 5 wt% to about 40 wt%, or about 10 wt% % to 30% by weight, or from about 15% to about 25% by weight, from about 10% to about 70% by weight, or from about 20% to about 60% by weight, or from about 25% by weight. aerosol-forming material in an amount of about 40% by weight (all calculated on a dry weight basis), about 10% to about 50% by weight, or about 20% to about 40% by weight, or about 25% to about 30% by weight; The composition may have a flavoring agent in an amount of Suitably, the amorphous solid of the second aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 30% to about 60% by weight; aerosol-forming material in an amount from about 10% to about 40% by weight; and a flavoring agent in an amount from about 20% to about 50% by weight.

In embodiments in which the amorphous solid of the aerosol-generating material in the consumable comprises an acid, in some such embodiments the amorphous solid comprises:
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
0.1 to 10% by weight of acid;
, where these weights are calculated on a dry weight basis.

In these embodiments, the amorphous solid may have the following composition (all calculated on a dry weight basis): from about 5% to about 40% by weight, or from about 10% to 30% by weight %, or in an amount of from about 15% to about 25% by weight, from about 10% to about 50%, or from about 20% to about 40%, or from about 25% to about 35% by weight. an amount of aerosol-forming material (all calculated on a dry weight basis) of from about 0.1% to about 8%, or from about 0.5% to about 7%, or from about 1% to about 5% by weight , or acid in an amount of about 1% to about 3% by weight. Suitably, the amorphous solid of the second aerosol-generating material may have the following composition (all calculated on a dry weight basis): gel in an amount of about 40% to about 70% by weight; an agent, an aerosol-forming material in an amount from about 20% to about 50% by weight, and an acid in an amount from about 0.1% to about 5% by weight.

Amorphous Solid Compositions The following discussion of amorphous solid compositions applies independently to each amorphous solid of the aerosol-generating material present in the consumables of the present invention.

In some examples, an amorphous solid may have a thickness of about 0.015 mm to about 1.0 mm. Suitably, the thickness may range from about 0.05 mm, 0.1 mm, or 0.15 mm to about 0.5 mm, 0.3 mm or 0.2 mm. The inventors have found that an amorphous solid with a thickness of 0.2 mm is particularly suitable. In some embodiments, an amorphous solid may have a thickness of about 0.1-0.2 mm. Amorphous solids may comprise more than one layer, and thicknesses described herein refer to the combined thickness of these layers.

The inventors have found that heating efficiency is compromised if the amorphous solid is too thick. This adversely affects power consumption in use. Conversely, if the amorphous solid is too thin, it will be difficult to manufacture and handle. That is, very thin materials are more difficult to cast and can be brittle and impair aerosol formation during use.

The inventors have found that the amorphous solid thicknesses defined herein optimize material properties given these competing considerations.

The thickness specified herein is the average thickness of the material. In some examples, the thickness of the amorphous solid may vary by 25%, 20%, 15%, 10%, 5%, or 1% or less.

In some examples, an amorphous solid may be heated once to produce an aerosol. In some examples, the amorphous solid may be heated two or more times, such as two or three times, to produce the aerosol.

A thicker amorphous solid may be used if the amorphous solid is heated more than once. For example, in some embodiments the thickness may be 0.2-0.5 mm.

In some examples, the amorphous solids may comprise 1-60% by weight gelling agent, where these weights are calculated on a dry weight basis.

In some embodiments, the gelling agent comprises a hydrocolloid. In some embodiments, the gelling agent is alginate, pectin, starch (and derivatives), cellulose (and derivatives such as methylcellulose, hydroxypropylcellulose, and carboxymethylcellulose (CMC)), gums, silica or silicone compounds. , clay, polyvinyl alcohol, and combinations thereof. For example, in some embodiments, the gelling agent is alginate, pectin, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose, pullulan, xanthan gum, guar gum, carrageenan, agarose, acacia gum, fumed silica, PDMS, silicic acid. It comprises one or more of sodium, kaolin, and polyvinyl alcohol. In some examples, the gelling agent comprises alginate and/or pectin and may be combined with a hardening agent (such as a calcium source) during formation of the amorphous solid. In some examples, the amorphous solid may comprise calcium cross-linked alginate and/or calcium cross-linked pectin.

In some instances, the gelling agent may be combined with a hardening agent (such as a calcium source) during formation of the amorphous solid.

In examples, the hardening agent comprises or consists of calcium acetate, calcium formate, calcium carbonate, calcium bicarbonate, calcium chloride, calcium lactate, or combinations thereof. In some examples, the hardening agent comprises or consists of calcium formate and/or calcium lactate. In certain examples, the hardening agent comprises or consists of calcium formate. The inventors have determined that using calcium formate as a stiffening agent typically results in amorphous solids with higher tensile strength and higher elongation resistance.

The total amount of hardening agent, eg, calcium source, may be 0.5-5% by weight (calculated on a dry weight basis). Suitably, the total amount may be from about 1 wt%, 2.5 wt%, or 4 wt% to about 4.8 wt%, or 4.5 wt%. The inventors have found that adding too little curing agent results in an amorphous solid which does not stabilize the amorphous solid components and causes these components to fall out of the amorphous solid. I found that there is a possibility that We have found that adding too much curing agent results in an amorphous solid that is very sticky and results in poor handling.

When the amorphous solid does not contain tobacco, a higher amount of hardener may need to be applied. In some examples, therefore, the total amount of curing agent, calculated on a dry weight basis, may be 0.5 to 12 weight percent, such as 5 to 10 weight percent. Suitably, the total amount may be from about 5%, 6%, or 7% to about 12%, or 10% by weight. In this example, amorphous solids generally do not include tobacco.

In some embodiments, the gelling agent comprises alginate, and the alginate is present in the amorphous solid in an amount of 10-30% by weight (calculated on a dry weight basis) of the amorphous solid. In some embodiments, alginate is the only gelling agent present in the amorphous solid. In other embodiments, the gelling agent comprises alginate and at least one additional gelling agent such as pectin.

In some embodiments, the gelling agent comprises a mixture of alginate and carboxymethylcellulose (CMC). Suitably the gelling agent comprises a higher amount of CMC than alginate. For example, in some instances the ratio of CMC to alginate is about 5:1, about 3:1, about 2:1, or about 1.5:1, such as 5:1 to 1.5: within the range of 1.

In some embodiments, amorphous solids may include gelling agents comprising carrageenan.

In some embodiments, the gelling agent may comprise one or more compounds selected from cellulosic gelling agents, non-cellulosic gelling agents, guar gum, acacia gum, and combinations thereof.

In some embodiments, the cellulosic gelling agent is hydroxypropylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose (CMC), hydroxypropylmethylcellulose (HPMC), methylcellulose, ethylcellulose, cellulose acetate (CA), cellulose acetate. selected from the group consisting of butyrate (CAB), cellulose acetate propionate (CAP), and combinations thereof.

In some embodiments, the gelling agent comprises one or more of hydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose (HPMC), carboxymethylcellulose, guar gum, or acacia gum (or one of them). more than one).

In some embodiments, gelling agents include, but are not limited to, agar, xanthan gum, gum arabic, guar gum, locust bean gum, pectin, carrageenan, starch, alginates, and combinations thereof. It comprises (or is) one or more non-cellulosic gelling agents. In preferred embodiments, the non-cellulosic gelling agent is alginate or agar.

Suitably, the amorphous solids are about 5 wt%, 10 wt%, 15 wt%, or 20 wt% to about 80 wt%, 70 wt%, 60 wt%, 55 wt%, 50 wt%, 45 wt%. It may comprise 40% by weight, or 35% by weight of aerosol-forming material (all calculated on a dry weight basis). Aerosol-forming materials may act as plasticizers. For example, the amorphous solid may comprise 10-60%, 15-50%, or 20-40% by weight of the aerosol-forming material. In some examples, the aerosol-forming material comprises one or more compounds selected from erythritol, propylene glycol, glycerol, triacetin, sorbitol and xylitol. In some examples, the aerosol-forming material comprises, consists essentially of, or consists of glycerol. The inventors have found that if the content of aerosol-forming material is too high, the amorphous solid may absorb water, resulting in a material that does not produce an adequate consumption experience when used. rice field. The inventors have found that if the content of aerosol-forming material is too low, the amorphous solid may become brittle and easily broken.

In some embodiments, the aerosol forming agent is one or more polyhydric alcohols such as propylene glycol, triethylene glycol, 1,3-butanediol, and glycerin, esters of polyhydric alcohols such as glycerol mono- , di- or triacetates, and/or aliphatic esters of mono-, di- or polycarboxylic acids such as dimethyldodecanedioate and dimethyltetradecanedioate.

In embodiments in which the amorphous solids comprise the flavorant, suitably the amorphous solids comprise about 60%, 50%, 40%, 30%, 20%, 10%, or 5% by weight. With up to weight percent flavorings. In some examples, the amorphous solids are at least about 0.5%, 1%, 2%, 5%, 10%, 20%, or 30% by weight flavoring agent (all dry weight). calculated by reference). For example, amorphous solids may contain 0.1-60%, 1-60%, 5-60%, 10-60%, 20-50%, or 30-40% by weight of flavoring agents. You may prepare. In some examples, the flavoring agent (if present) comprises, consists essentially of, or consists of menthol. In some examples, the amorphous solid does not contain flavorants.

In embodiments where the aerosol-generating material of the present invention comprises an active agent, in some instances the amorphous solid comprises tobacco material and/or nicotine. For example, the amorphous solid may comprise powdered tobacco and/or nicotine and/or tobacco extract. In some examples, amorphous solids are about 1 wt%, 5 wt%, 10 wt%, 15 wt%, 20 wt%, or 25 wt% to about 70 wt%, 50 wt%, 45 wt%. , or 40% by weight (calculated on a dry weight basis) of active material. In some examples, amorphous solids are about 1 wt%, 5 wt%, 10 wt%, 15 wt%, 20 wt%, or 25 wt% to about 70 wt%, 60 wt%, 50 wt%. , 45% by weight, or 40% by weight (calculated on a dry weight basis) of tobacco material and/or nicotine.

In embodiments where the aerosol-generating material comprises an active agent such as tobacco extract, in some instances the amorphous solids may comprise 5-60% by weight (calculated on a dry weight basis) of tobacco extract. good. In some examples, amorphous solids are from about 5%, 10%, 15%, 20%, or 25% to about 55%, 50%, 45%, or 40% by weight. (calculated on a dry weight basis) of tobacco extract. For example, the amorphous solid may comprise 5-60 wt%, 10-55 wt%, or 25-55 wt% tobacco extract. The tobacco extract contains 1%, 1.5%, 2%, or 2.5% to about 6%, 5%, 4.5%, or 4% by weight amorphous solids ( (calculated on a dry weight basis) nicotine. In some instances, no nicotine other than that resulting from the tobacco extract may be present in the amorphous solid.

In some embodiments, the amorphous solid does not comprise tobacco material, but does comprise nicotine. In some such examples, amorphous solids are from about 1 wt%, 2 wt%, 3 wt%, or 4 wt% to about 20 wt%, 15 wt%, 10 wt%, or 5 wt%. (calculated on a dry weight basis) of nicotine. For example, the amorphous solid may comprise 1-20% by weight, or 2-5% by weight of nicotine.

In embodiments where the amorphous solid comprises an acid, the amorphous solid comprises 1-20 wt%, 5-15 wt%, or 8-12 wt% (calculated on a dry weight basis) of an acid, such as 1 wt. %, 2 wt %, 3 wt %, or 4 wt % to about 20 wt %, 15 wt %, 10 wt %, or 5 wt % (calculated on a dry weight basis) of acid.

While not wishing to be bound by theory, it is believed that the inclusion of acid in the amorphous solid protonates the nicotine and produces an aerosol that is more satisfying to some users of smoking devices. .

The aerosol-generating material or amorphous solid may comprise an acid.

The inclusion of acid is particularly preferred in embodiments in which the aerosol-generating material or amorphous solid comprises nicotine. In such embodiments, the presence of acid can stabilize dissolved species in the slurry from which the aerosol-generating material or amorphous solid is formed. The presence of acid can reduce or substantially prevent nicotine evaporation during slurry drying, thereby reducing nicotine loss during manufacturing.

In some such embodiments, the acid may comprise an acidic functional group, which is in the range of 2-6, such as in the range of 3-6, or in the range of 4-5, measured at 25°C. It has a pK _a value of

In some such embodiments, the acid may have a boiling point in the range of 70°C to 450°C, such as in the range of 100°C to 320°C.

In some such embodiments, the amorphous solid may comprise 1-20% by weight of acid, which has _a pKa value in the range of 2-6 when measured at 25°C. Having functional groups, the acid has a boiling point in the range of 70°C to 350°C.

In some such embodiments, the acid may be an organic acid.

In some of these embodiments, the acid may be at least one of monobasic, dibasic, and tribasic.

In some such embodiments, the acid may contain at least one carboxyl functional group.

In some such embodiments, the acid may be at least one of an alpha-hydroxy acid, carboxylic acid, dicarboxylic acid, tricarboxylic acid, and keto acid.

In some such embodiments, the acid may be an alpha-keto acid.

In some such embodiments, the acid is succinic acid, lactic acid, benzoic acid, citric acid, tartaric acid, fumaric acid, levulinic acid, acetic acid, malic acid, formic acid, sorbic acid, benzoic acid, propanoic acid, and pyruvate. It may be at least one of acids.

Preferably the acid is lactic acid. In other embodiments, the acid is benzoic acid.

In other embodiments, the acid may be an inorganic acid. In some of these embodiments the acid may be a mineral acid. In some such embodiments, the acid may be at least one of sulfuric acid, hydrochloric acid, boric acid, and phosphoric acid.

In some embodiments, the acid is levulinic acid.

In embodiments in which the amorphous solid comprises an acid, the amorphous solid comprises 1 wt%, 2 wt%, 3 wt%, or 4 wt% to about 20 wt%, 15 wt%, 10 wt%, or 5 wt%. There may be a weight percent organic acid (calculated on a dry weight basis).

In embodiments in which the amorphous solid comprises an acid, the amorphous solid comprises 1 wt%, 2 wt%, 3 wt%, or 4 wt% to about 20 wt%, 15 wt%, 10 wt%, or 5 wt%. A weight percent (calculated on a dry weight basis) of acids with carboxyl functionality may be provided.

In embodiments in which the amorphous solid comprises an acid, the amorphous solid comprises 1 wt%, 2 wt%, 3 wt%, or 4 wt% to about 20 wt%, 15 wt%, 10 wt%, or 5 wt%. A weight percent (calculated on a dry weight basis) of an acid containing an acidic functional group may be provided, which has _a pKa value of 2-6 when measured at 25°C.

In certain embodiments, the aerosol-generating material or amorphous solid comprises a gelling agent, including a cellulosic gelling agent and/or a non-cellulosic gelling agent, an active agent, and an acid.

Amorphous solids, in some examples, can be hydrogels, with less than about 20%, 15%, 12%, or 10% water by weight, calculated on a wet weight basis (WWB). Prepare. In some examples, the amorphous solid may comprise at least about 1 wt%, 2 wt%, or 5 wt% water (by WWB). Amorphous solids comprise from about 1% to about 15%, or from about 5% to about 15%, by weight water calculated on a wet weight basis. Preferably, the moisture content of the amorphous solids is from about 5%, 7%, or 9% by weight (WWB) to about 15%, 13%, or 11% by weight, most preferably about It may be 10% by weight.

Amorphous solids may be made from gels, which may further comprise a solvent comprised between 0.1 and 50% by weight. However, the inventors have found that the inclusion of a solvent in which the flavoring agent can dissolve reduces the gel stability, and the flavoring agent may exit the gel and crystallize. Thus, in some instances, the gel does not contain solvents in which flavorants can be dissolved.

In some examples, the amorphous solid comprises 1 to 60 weight percent filler, such as 5 to 50 weight percent, 10 to 40 weight percent, or 15 to 30 weight percent filler. In some such examples, the amorphous solids are at least 1 wt% filler, such as at least 5 wt%, at least 10 wt%, at least 20 wt%, at least 30 wt%, at least 40 wt%, or with at least 50% by weight of filler.

In some embodiments, the amorphous solids are less than 60 wt% filler, such as 1 wt% to 60 wt%, or 5 wt% to 50 wt%, or 5 wt% to 30 wt%, or 10% to 20% filler by weight.

In other embodiments, the amorphous solid comprises less than 20 wt%, preferably less than 10 wt% or less than 5 wt% filler. In some examples, the amorphous solid comprises less than 1 wt% filler, and in some examples contains no filler.

Fillers, if present, may be one or more inorganic filler materials such as calcium carbonate, perlite, vermiculite, diatomaceous earth, colloidal silica, magnesium oxide, magnesium sulfate, magnesium carbonate, and suitable inorganic adsorbents (molecular sieves). etc.). The filler may comprise one or more organic filler materials such as wood pulp, cellulose and cellulose derivatives. (such as methylcellulose, hydroxypropylcellulose, and carboxymethylcellulose (CMC)). In some examples, the amorphous solid comprises less than 1 wt% filler, and in some examples, no filler. In particular, in some instances the amorphous solid does not comprise calcium carbonate, such as chalk.

In certain embodiments that include fillers, the fillers are fibrous. For example, the filler may be a fibrous organic filler material such as wood pulp, hemp fiber, cellulose or cellulose derivatives. (such as methylcellulose, hydroxypropylcellulose, and carboxymethylcellulose (CMC)). While not wishing to be bound by theory, it is believed that including fibrous fillers in the amorphous solid may increase the tensile strength of the material.

In some embodiments, the amorphous solid does not comprise tobacco fibers. In certain embodiments, amorphous solids do not comprise fibrous materials.

In some embodiments, the aerosol-generating material does not comprise tobacco fibers. In certain embodiments, the aerosol-generating material does not comprise fibrous material.

In some embodiments, the aerosol-generating material does not comprise tobacco fibers. In certain embodiments, the aerosol-generating material does not comprise fibrous material.

In some embodiments, the consumable does not comprise tobacco fiber. In certain embodiments, the consumable does not comprise fibrous material.

Aerosol-generating materials comprising amorphous solids may have any suitable areal density, eg, from 30 g/m ² to 120 g/m ² . In some embodiments, the aerosol-generating material may have an areal density of about 30-70 g/m ² , or about 40-60 g/m ² . In some embodiments, the amorphous solid may have an areal density of about 80-120 g/m ² , or about 70-110 g/m ² , or especially about 90-110 g/m ² .

In some examples, the amorphous solid in sheet form may have a tensile strength of from about 200 N/m to about 900 N/m. In some examples, such as examples in which the amorphous solid does not comprise a filler, the amorphous solid has a tensile strength of 200 N/m to 400 N/m, or 200 N/m to 300 N/m, or about 250 N/m. may have In some examples, such as examples in which the amorphous solid comprises a filler, the amorphous solid has a tensile strength of 600 N/m to 900 N/m, or 700 N/m to 900 N/m, or about 800 N/m. may have.

Amorphous solids may be provided with colorants. Addition of colorants can change the visual appearance of the amorphous solid. The presence of colorants in amorphous solids can enhance the visual appearance of amorphous solids and aerosol-generating materials. By adding a colorant to the amorphous solid, the amorphous solid can be color matched to other components of the aerosol-generating material or articles comprising the amorphous solid.

Various colorants may be used depending on the desired color of the amorphous solid. The color of the amorphous solid may be white, green, red, purple, blue, brown, or black, for example. Other colors are also envisioned. Natural or synthetic coloring agents such as natural or synthetic dyes, food grade coloring agents, and pharmaceutical grade coloring agents may be used. In certain embodiments, the coloring agent is caramel, which can impart a brown appearance to the amorphous solid. In such embodiments, the color of the amorphous solid may be similar to the color of other components (such as tobacco material) in the aerosol-generating material comprising the amorphous solid. In some embodiments, the addition of a colorant to the amorphous solid renders the amorphous solid visually indistinguishable from other components in the aerosol-generating material.

The colorant may be incorporated during the formation of the amorphous solid (e.g., when forming a slurry with the material that forms the amorphous solid), or the colorant may be incorporated into the amorphous solid after its formation. may be applied (eg, by spraying the colorant onto the amorphous solid).

Methods of Making Consumables The present invention also provides methods of making consumables for use with non-combustion aerosol delivery devices. This method
providing a support;
depositing on a support at least two separate portions of a slurry comprising a gelling agent, an aerosol forming agent, and at least one of an active agent, a flavorant and an acid;
drying at least two separate portions of the slurry to obtain a first aerosol-generating material and a second aerosol-generating material, the first and second aerosol-generating materials attached to a support; there is a step and
forming a consumable;
wherein each of the first and second aerosol-generating materials comprises an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein the weights are calculated on a dry weight basis and the amorphous solids of the first aerosol-generating material have a different composition than the composition of the amorphous solids of the second aerosol-generating material.

The embodiments described throughout this application in connection with the consumable of the present invention apply mutatis mutandis to the method of manufacturing the consumable.

The present invention also includes use of the consumables described throughout this application in non-combustion aerosol delivery devices. The device is arranged to generate an aerosol from the consumable when the consumable is used with the non-combustion aerosol delivery device.

The embodiments described throughout this application in connection with the consumable of the present invention apply mutatis mutandis to the use of the consumable.

Consumables In some examples, the aerosol-generating materials (eg, the first and second aerosol-generating materials) are attached to a support. Advantageously, the support is a flat support. In some examples, the support may be substantially or completely impermeable to gases and/or aerosols. This prevents the aerosol or gas from passing through the support, thereby controlling flow and ensuring good delivery to the user. This can also be used to prevent gases/aerosols from forming condensation or other deposits during use, for example on the surfaces of heaters provided in non-combustion aerosol delivery systems. In this way, consumption efficiency and hygiene can be improved in some instances.
Accordingly, in certain embodiments, the present invention provides consumables for use within non-combustion aerosol delivery systems. This consumable is
a support;
a first aerosol-generating material attached to a support;
a second aerosol-generating material attached to the support;
and each aerosol-generating material comprises an amorphous solid, the amorphous solid comprising
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
, where these weights are calculated on a dry weight basis,
The amorphous solid of the first aerosol-generating material has a different composition than the amorphous solid of the second aerosol-generating material.

The support may be at least partially porous in the regions of its surface that abut the amorphous solid. The inventors have found that such a support is particularly suitable for the present invention, the porous section of the support abutting the amorphous solid and forming a strong bond. The amorphous solid is formed by drying the gel and, without being limited by theory, the slurry forming the amorphous solid partially impregnates the porous material of the support, As a result, it is believed that the support is partially bonded to the amorphous solid as it hardens and forms crosslinks. This results in a strong bond between the amorphous solid and the support.

Additionally, surface roughness can contribute to the strength of the bond between the amorphous solid and the support. We have found that the roughness of the paper (of the surface contacting the aerosol-generating material) is preferably in the range of 50-1000 Bekk seconds, preferably in the range of 50-150 Bekk seconds, preferably 100 Bekk seconds. seconds (measured over the pressure interval of 50.66-48.00 kPa). (A Bekk smoothness tester is an instrument used to measure the smoothness of paper surfaces. In this tester, air at a specified pressure is forced between a smooth glass surface and a paper sample. The time (in seconds) for a fixed volume of air to penetrate between these surfaces is the "Beck smoothness").

Conversely, the surface of the support facing away from the amorphous solid may be placed in contact with the heater, and a smoother surface may provide more efficient heat transfer. Thus, in some instances, the support is arranged to have a rougher side that abuts the amorphous solid and a smoother side that faces away from the amorphous solid.

In one particular example, the support may itself be a laminate structure. For example, the support may comprise a foil backed with cardboard, the cardboard layer abutting the amorphous solid, the properties discussed in the preceding paragraphs being provided by this abutment. The foil backing is substantially impermeable and provides control of the aerosol flow path. A metal foil backing can also serve to conduct heat to the amorphous solid.

In another example, a foil layer of cardboard backing foil abuts an amorphous solid. The foil is substantially impermeable, preventing moisture imparted in the amorphous solid from being absorbed by the paper, which can weaken the structural integrity of the paper.

In some examples, the support is formed from or comprises a metal foil (such as aluminum foil). A metallic support may allow better transfer of thermal energy to the amorphous solid. Additionally or alternatively, the metal foil may serve as a susceptor within the induction heating system. In certain embodiments, the support comprises a metal foil layer and a support layer (such as cardboard). In these embodiments, the metal foil layer may have a thickness of less than 20 μm, such as from about 1 μm to about 10 μm, preferably about 5 μm.

This consumable is also referred to herein as a cartridge. This consumable may be adapted for use in a THP, hybrid device, or another aerosol generating device. In some examples, the consumable may be in the form of a rod. In some examples, the consumable may further comprise filters and/or cooling elements as previously described. In some examples, the consumable may be surrounded by packaging material such as paper.

The consumable may further comprise a vent. These may be provided on the sidewalls of the consumable. In some examples, vents may be provided in filters and/or cooling elements. These holes allow cool air to be drawn into the consumable during use, which can mix with the heated volatiles, thereby cooling the aerosol.

Venting promotes the production of visible heating volatiles from the consumable when the consumable is heated during use. The heated volatiles are visualized by cooling the heated volatiles such that supersaturation of the heated volatiles occurs. The heated volatiles then undergo droplet formation (also known as nucleation), and ultimately the size of the heated volatiles aerosol particles increases due to further condensation of the heated volatiles and from the heated volatiles. Increased by coalescence of newly formed droplets.

In some examples, the ratio of cold air to the sum of heated volatiles and cold air (known as the ventilation ratio) is at least 15%. A ventilation ratio of 15% allows the heating volatiles to be visualized by the method described above. Visibility of the heated volatiles allows the user to identify when the volatiles have been produced, enhancing the sensory experience of the smoking experience.

In another example, the ventilation ratio is between 50% and 85% to further cool the heated volatiles. In some examples, the ventilation ratio may be at least 60% or 65%.

Referring to FIGS. 1 and 2, partially cutaway cross-sectional and perspective views of an example aerosol-generating consumable 101 are shown. Consumable 101 is adapted for use with a device having a power source and heater. The consumable 101 of this embodiment is particularly suitable for use with the device 51 shown in FIGS. 5-7, described below. In use, consumable 101 can be removably inserted into the device at insertion point 20 of device 51 shown in FIG.

An example consumable 101 is in the form of a generally cylindrical rod that includes a body of aerosol-generating material 103 and a filter assembly 105 in the form of a rod. The aerosol-generating material comprises the amorphous solid material described herein. In some embodiments, it may be included in sheet form. In some embodiments, it may be included in the form of shredded sheets. In some embodiments, the aerosol-generating materials described herein may be incorporated in sheet form and shredded form.

Filter assembly 105 includes three segments: cooling segment 107 , filter segment 109 and mouth end segment 111 . The consumable 101 has a first end 113, also known as the oral or proximal end, and a second end 115, also known as the distal end. A body of aerosol-generating material 103 is located on the distal end 115 side of the consumable 101 . In one example, cooling segment 107 is adjacent body of aerosol-generating material 103 , between body of aerosol-generating material 103 and filter segment 109 such that cooling segment 107 is in abutting relationship with aerosol-generating material 103 and filter segment 109 . are placed as follows. In other examples, there may be separations between the body of aerosol-generating material 103 and the cooling segment 107 and between the body of aerosol-generating material 103 and the filter segment 109 . Filter segment 109 is positioned between cooling segment 107 and mouth end segment 111 . The mouth end segment 111 is located on the proximal end 113 side of the consumable 101 and is adjacent to the filter segment 109 . In one example, filter segment 109 is in abutting relationship with mouth end segment 111 . In one embodiment, the overall length of filter assembly 105 is between 37 mm and 45 mm, more preferably the overall length of filter assembly 105 is 41 mm.

In one example, the rods of aerosol-generating material 103 have a length between 34 mm and 50 mm, preferably between 38 mm and 46 mm, preferably between 42 mm.

In one example, the overall length of the consumable 101 is between 71 mm and 95 mm, preferably between 79 mm and 87 mm, preferably 83 mm.

One axial end of the body of aerosol-generating material 103 is visible at the distal end 115 of the consumable 101 . However, in other embodiments, the distal end 115 of the consumable 101 may include an end member (not shown) that covers one axial end of the body of aerosol-generating material 103 .

The body of aerosol-generating material 103 is joined to the filter assembly 105 by an annular tipping paper (not shown), the annular tipping paper being disposed substantially around the filter assembly 105 so as to enclose the filter assembly 105 and containing the aerosol-generating material. It extends partially along the length of body 103 . In one example, the tipping paper is made from 58 GSM standard tipping base paper. In one example, the tipping paper has a length of 42mm to 50mm, preferably 46mm.

In one example, cooling segment 107 is an annular tube that is positioned around and defines a void within the cooling segment. This void provides a chamber through which the heated volatiles produced from the body of aerosol-generating material 103 flow. Cooling segment 107 is hollow to provide a chamber for aerosol accumulation, but is resistant to axial compressive forces and bending moments that may occur during manufacture and use of consumable 101 during insertion into device 51. Rigid enough to withstand. In one example, the wall thickness of cooling segment 107 is about 0.29 mm.

Cooling segment 107 provides a physical displacement between aerosol-generating material 103 and filter segment 109 . The physical displacement provided by cooling segment 107 creates a thermal gradient across the length of cooling segment 107 . In one example, the cooling segment 107 provides a temperature difference of at least 40 degrees Celsius between the heated volatiles entering the first end of the cooling segment 107 and the heated volatiles exiting the second end of the cooling segment 107. configured as In one example, the cooling segment 107 provides a temperature difference of at least 60 degrees Celsius between the heated volatiles entering the first end of the cooling segment 107 and the heated volatiles exiting the second end of the cooling segment 107. configured as This temperature differential across the length of cooling element 107 protects temperature sensitive filter segment 109 from the high temperature of aerosol-generating material 103 as aerosol-generating material 103 is heated by device 51 . If no physical displacement is provided between the filter segment 109 and the body of aerosol-generating material 103 and the heating element of the device 51, the temperature-sensitive filter segment 109 will be damaged during use and become unusable. function may not be effectively exhibited.

In one example, the length of cooling segment 107 is at least 15 mm. In one example, the cooling segment 107 has a length of 20 mm to 30 mm, more specifically 23 mm to 27 mm, more specifically 25 mm to 27 mm, preferably 25 mm.

The cooling segment 107 is made of paper, which means that the cooling segment 107 is constructed from a material that, in use, does not produce compounds of concern (e.g., toxic compounds) when adjacent to the heater of device 51. means. In one example, cooling segment 107 is manufactured from a spiral wound paper tube that provides a hollow internal chamber but maintains mechanical rigidity. Spiral wound paper tubes can meet the stringent dimensional accuracy requirements of high-speed manufacturing processes in terms of tube length, outer diameter, roundness and straightness.

In another example, cooling segment 107 is a recess made from stiff plug wrap or tipping paper. The stiff plug wrap or tipping paper is manufactured to have sufficient stiffness to withstand axial compressive forces and bending moments that may occur during manufacture and use of the consumable 101 during insertion into the device 51. be.

Filter segment 109 may be formed from any filter material sufficient to remove one or more volatile compounds from the heated volatiles from the aerosol-generating material. In one example, filter segment 109 is made from a monoacetate material such as cellulose acetate. Filter segment 109 provides cooling and reduced irritation of heat volatiles without depleting the amount of heat volatiles to levels unsatisfactory to the user.

In some embodiments, a capsule (not shown) may be provided within filter segment 109 . The capsule may be substantially centered in the filter segment 109 both radially and longitudinally of the filter segment 109 . In other examples, the capsule may be off-center in one or more dimensions. In some instances, if a capsule is present, the capsule may contain volatile ingredients such as flavorants and aerosol-forming agents.

The density of the cellulose acetate tow material of filter segment 109 controls the pressure drop across filter segment 109 and thus the draw resistance of consumable 101 . Therefore, the selection of material for filter segment 109 is important in controlling the draw resistance of consumable 101 . Additionally, the filter segment performs a filtering function in consumable 101 .

In one example, filter segment 109 is made of 8Y15 grade filter tow material. The filter tow material provides a filtering effect on the heated volatile material while reducing the size of condensed aerosol droplets resulting from the heated volatile material.

The presence of filter segment 109 provides an insulating effect by further cooling heated volatiles exiting cooling segment 107 . This additional cooling effect reduces the contact temperature of the user's lips to the surface of filter segment 109 .

In one example, filter segment 109 is between 6mm and 10mm in length, preferably 8mm.

Mouth end segment 111 is an annular tube and is disposed around and defines a void within mouth end segment 111 . This void provides a chamber for heated volatiles flowing from filter segment 109 . Mouth end segment 111 is hollow to provide a chamber for aerosol accumulation, but avoids axial compressive forces and bending that may occur during manufacture and during use of the consumable during insertion into device 51. It has sufficient stiffness to withstand the moment. In one example, the wall thickness of mouth end segment 111 is about 0.29 mm. In one example, the mouth end segment 111 has a length of 6 mm to 10 mm, preferably 8 mm.

Mouth end segment 111 may be manufactured from a spiral wound paper tube that provides a hollow interior chamber but maintains significant mechanical rigidity. Spiral wound paper tubes can meet the stringent dimensional accuracy requirements of high-speed manufacturing processes in terms of tube length, outer diameter, roundness and straightness.

Mouth end segment 111 serves the function of preventing liquid condensate that accumulates at the outlet of filter segment 109 from coming into direct contact with the user.

In one example, it is understood that mouth end segment 111 and cooling segment 107 may be formed from a single tube, with filter segment 109 disposed within that tube to separate mouth end segment 111 and cooling segment 107 . want to be

3 and 4, a partially cutaway cross-sectional view and a perspective view of an example consumable 301 are shown. The reference numbers shown in FIGS. 3 and 4 correspond to the reference numbers shown in FIGS. 1 and 2, but the number has been increased by two hundred.

In the example of consumable 301 shown in FIGS. 3 and 4, venting area 317 is provided in consumable 301 to allow air to flow from the exterior of consumable 301 to the interior of consumable 301 . In one example, vent region 317 takes the form of one or more vent holes 317 formed through the outer layer of consumable 301 . This vent may be located in the cooling segment 307 to help cool the consumable 301 . In one example, vent region 317 comprises one or more rows of holes, preferably each row of holes along the perimeter of consumable 301 in a cross-section substantially perpendicular to the longitudinal axis of consumable 301. placed.

In one example, there are 1-4 rows of vents to provide ventilation for consumable 301 . Each row of vents may have from 12 to 36 vents 317 . The diameter of the vent 317 can be, for example, 100-500 μm. In one example, the axial spacing between rows of vent holes 317 is between 0.25 mm and 0.75 mm, preferably 0.5 mm.

In one example, vent holes 317 have a uniform size. In another example, vent holes 317 have different sizes. The vent holes are made using any suitable technique, such as one or more of laser techniques, mechanical drilling of the cooling segments 307, or pre-drilling of the cooling segments 307 before they are formed in the consumable 301. can do. Vents 317 are positioned to effectively cool consumable 301 .

In one example, the row of vent holes 317 is located at least 11 mm from the proximal end 313 of the consumable, preferably 17 mm to 20 mm from the proximal end 313 of the consumable 301 . The position of the vent 317 is determined so that the user does not block the vent 317 when using the consumable 301 .

By providing a row of vents 17 mm to 20 mm from the proximal end 313 of the consumable 301, vents 317 are opened when the consumable 301 is fully inserted into the device 51, as seen in FIGS. It can be placed outside the device 51 . By locating the vents on the outside of the device, unheated air can enter the consumable 301 from outside the device 51 through the vents to help cool the consumable 301 .

The length of cooling segment 307 is such that cooling segment 307 is partially inserted into device 51 when consumable 301 is fully inserted into device 51 .
The length of this cooling segment 307 serves the primary function of providing a physical gap between the heating apparatus of device 51 and the heat-sensitive filter apparatus 309, and the length of consumable 301 is fully inserted into device 51. Sometimes, vent holes 317 are located within the cooling segment while providing a second function that allows them to be located outside the device 51 as well. As can be seen from FIGS. 6 and 7, the majority of cooling element 307 is located within device 51 . However, cooling element 307 has a portion that extends outside device 51 . A vent hole 317 is located in this portion of the cooling element 307 that extends out of the device 51 .

5-7 in more detail, an aerosol-generating material is configured to heat to volatilize at least one component of said aerosol-generating material, typically forming an inhalable aerosol. An example of device 51 is shown. Device 51 is a heating device that releases a compound by heating, but not burning, an aerosol-generating material.

The first end 53 is sometimes referred to herein as the oral or proximal end 53 of the device 51 and the second end 55 is herein referred to as the distal end 55 of the device 51 . It is sometimes called Device 51 has an on/off button 57 to enable the entire device 51 to be activated/deactivated as desired by the user.

Device 51 includes a housing 59 for locating and protecting various internal components of device 51 . In the illustrated example, the housing 59 comprises a unitary sleeve 11 that surrounds the outer edge of the device 51 , the sleeve 11 comprising a top panel 17 generally forming the "top" of the device 51 and a "bottom" of the device 51 . It is capped with a bottom panel 19 which generally forms a . In another example, the housing includes a top panel 17 and a bottom panel 19, as well as a front panel, a rear panel, and a pair of opposing side panels.

The top panel 17 and/or bottom panel 19 may be removably secured to the unitary sleeve 11 to allow easy access to the interior of the device 51, or the user may, for example, remove the device 51 from the device 51. It may be "permanently" secured to the unitary sleeve 11 to prevent access to the interior. In one example, panels 17 and 19 are made of plastic material (including glass-filled nylon or the like formed by injection molding) and unitary sleeve 11 is made of aluminum, although other materials and other manufacturing processes may be used. You may

The top panel 17 of the device 51 has an opening 20 at the mouth end 53 of the device 51 through which, in use, the user can pass consumables 101, 301, including aerosol-generating materials. It can be inserted into and removed from device 51 .

Housing 59 has disposed or secured therein heating device 23, control circuitry 25, and power supply 27. As shown in FIG. In this example, heating device 23 , control circuitry 25 , and power source 27 are laterally adjacent (ie, adjacent when viewed from one end), and control circuitry 25 is positioned generally between heating device 23 and power source 27 . However, other arrangements are possible.

The control circuit 25 may include a controller, such as a microprocessor device, constructed and arranged to control the heating of the aerosol-generating material within the consumables 101, 301, as discussed further below.

Power source 27 may be, for example, a battery, which may be a rechargeable battery or a non-rechargeable battery. Examples of suitable batteries include, for example, lithium ion batteries, nickel batteries (eg, nickel cadmium batteries), alkaline batteries, and the like. A battery 27 is electrically coupled to the heating device 23 and provides power under the control of the control circuit 25 when needed to heat the aerosol-generating material in the consumable (as described above, the aerosol-generating material volatilize the aerosol-generating material without burning the ).

An advantage of placing the power source 27 laterally close to the heating device 23 is that a physically large power source 25 can be used without making the overall device 51 too long. Of course, in general, a physically larger power source 25 will have a higher capacity (i.e., total electrical energy that can be delivered, often measured in ampere-hours, etc.), and thus will increase the battery life of device 51. can be longer.

In one example, the heating device 23 is generally in the form of a hollow cylindrical tube having a hollow internal heating chamber 29 in which the consumable 101, 301 comprising the aerosol-generating material is heated during use. inserted for Various configurations of the heating device 23 are possible. For example, heating device 23 may comprise a single heating element or may be formed from multiple heating elements aligned along the longitudinal axis of heating device 23 . The or each heating element may be annular or tubular, or may be at least partially annular or at least partially tubular along its circumference. In one example, the or each heating element may be a thin film heater. Alternatively, the or each heating element may be made from a ceramic material. Examples of suitable ceramic materials include alumina and aluminum nitride ceramics, and silicon nitride ceramics, which may be laminated and sintered. Other heating configurations are possible, including, for example, induction heating, infrared heating elements (which heat by radiating infrared radiation), resistive heating elements formed by resistive electrical windings, and the like.

In one particular example, heating device 23 is supported by a stainless steel support tube and comprises a polyimide heating element. The heating device 23 is configured such that when the consumable 101 , 301 is inserted into the device 51 , substantially the entire body of the consumable 101 , 301 consisting of the aerosol-generating material 103 , 303 is inserted into the heating device 23 . dimensions are given.

The or each heating element independently heats selected zones of the aerosol-generating material, e.g., sequentially (as described above over time) or together (simultaneously) as desired. It may be arranged so that

The heating device 23 in this example is surrounded by insulation 31 along at least part of its length. Insulation 31 helps reduce heat passing from heating device 23 to the exterior of device 51 . This helps keep the power requirements of the heating device 23 low as it generally reduces heat losses. Insulation 31 also helps keep the exterior of device 51 cool during operation of heating device 23 . In one example, the insulator 31 may be a double walled sleeve providing a low pressure area between the two walls of the sleeve. That is, the insulator 31 may be, for example, a "vacuum" tube, ie, a tube that is at least partially evacuated to minimize heat transfer by conduction and/or convection. Other configurations for insulation 31 are possible, including the use of insulation (eg, including suitable foam-type materials) in addition to or instead of double-walled sleeves. For example.

Housing 59, like heating device 23, may further comprise various internal support structures 37 for supporting all internal components.

Device 51 includes a collar 33 extending around opening 20 and protruding from opening 20 into housing 59 , and a generally tubular chamber 35 disposed between collar 33 and one end of vacuum sleeve 31 . Further prepare. The chamber 35 further comprises a cooling structure 35f, which in this example comprises a plurality of cooling fins 35f spaced along the outer surface of the chamber 35, each cooling fin covering the outer surface of the chamber 35. arranged to surround When the consumable 101,301 is inserted into the device 51 over at least part of the length of the hollow chamber 35, there is an air gap 36 between the hollow chamber 35 and the consumable 101,301. Air gap 36 surrounds the entire perimeter of consumable 101 , 301 over at least a portion of cooling segment 307 .

Collar 33 includes a plurality of ridges 60 arranged around the perimeter of opening 20 and projecting into opening 20 . The ridge 60 occupies a space within the opening 20 such that the opening distance of the opening 20 at the location of the ridge 60 is less than the opening distance of the opening 20 at the location without the ridge 60 . The ridges 60 are configured to engage a consumable 101 , 301 inserted within the device to help secure it within the device 51 . The open spaces (not shown) defined by adjacent pairs of ridges 60 and the consumables 101,301 form ventilation paths around the outer surfaces of the consumables 101,301. These vent paths allow hot vapors escaping from the consumables 101, 301 to exit the device 51 and allow cooling air to flow to the device 51 around the consumables 101, 301 within the air gap 36. to

In operation, the consumables 101, 301 are removably inserted into the insertion point 20 of the device 51, as shown in Figures 5-7. Referring specifically to FIG. 6, in one example, the body of aerosol-generating material 103, 303 (which is located on the distal end 115, 315 side of the consumable 101, 301) is placed within the heating device 23 of the device 51. fully accommodated. Proximal ends 113, 313 of consumables 101, 301 extend out of device 51 and serve as a mouthpiece assembly for the user.

During operation, the heating device 23 heats the consumable 101,301 to volatilize at least one component of the aerosol-generating material from the body 103,303 of the aerosol-generating material.

The primary flow path for heated volatiles from the body of aerosol-generating material 103, 303 is axially through the consumable 101, 301, through the inner chamber of the cooling segment 107, 307, through the filter segment 109, 309. through mouth end segments 111, 313 to the user. In one example, the temperature of heated volatiles produced from the body of aerosol-generating material is between 60° C. and 250° C., which may exceed acceptable inhalation temperatures for a user. The heated volatiles are cooled as they travel through the cooling segments 107,307 and some volatiles condense on the inner surfaces of the cooling segments 107,307.

In the example of consumable 301 shown in FIGS. 3 and 4, cold air can enter cooling segment 307 through vent holes 317 formed in cooling segment 307 . This cold air mixes with the heated volatiles to further cool the heated volatiles.

Advantageously, the consumable of the present invention allows each of the first and second aerosol-generating materials to be aerosolized separately. In other words, the production of aerosol from each aerosol-generating material may be under separate control such that the production of aerosol produced by each aerosol-generating material can be individually varied. In embodiments where the non-combustion aerosol delivery system uses heat to generate the aerosol, each aerosol-generating material in the consumable may be under the control of a separate heat-generating component. In such embodiments, the temperature of each aerosol-generating material can be controlled separately to stimulate the release of a desired amount of aerosol from each aerosol-generating material. As such, the non-combustion aerosol delivery system is configured to allow a user to aerosolize the first and/or second aerosol-generating material according to personal preference. As a non-limiting example provided to illustrate the invention, the amorphous solid of the first aerosol-generating material may comprise a flavorant or no active substance, while the second The amorphous solid of the aerosol-generating material may comprise an active substance or no flavorant, and if the user wishes to inhale only the flavorant, the non-combustion aerosol delivery system can allow this, For example, a user may configure the non-combustion aerosol delivery device to aerosolize a first aerosol-generating material (comprising a flavorant) but not a second aerosol-generating material (comprising an active agent). Can be programmed. It is recognized that such systems may be further configured to allow users to obtain a wide variety of smoking experiences according to their preferences.

In some embodiments, the aerosol-generating material is depleted such that when used in a non-combustion aerosol delivery system, the aerosol-generating materials can be stimulated to generate aerosol under separate control from each other. placed in the product.

The advantage of the consumables of the present invention is that a single production line or facility can produce a single type of consumables, thereby providing a variety of user-preferred experiences. That is.

In some examples, a heater (eg, a heater in a non-combustion aerosol delivery system) may heat the amorphous solid to between 120° C. and 350° C. without burning the amorphous solid during use. In some examples, the heater may heat to 140° C. to 250° C. without burning the amorphous solid when in use.

The heater may comprise one or more electrical resistance heater(s) including one or more nichrome resistance heater(s) and/or one or more ceramic heater(s). The one or more heaters may comprise one or more induction heaters comprising a structure comprising one or more susceptors into which, in use, an article comprising an aerosol-generating material is inserted or or otherwise arranged chambers. Alternatively, or in addition, one or more susceptors may be provided in the aerosol-generating material. Other heating arrangements may be used.

Illustrative Embodiments The following embodiments are provided as examples to better explain how the invention may be practiced.

In one embodiment, a consumable for use with a non-combustion aerosol delivery device is provided. This consumable is
a first aerosol-generating material;
a second aerosol-generating material;
and the first aerosol-generating material comprises an amorphous solid, the amorphous solid comprising:
30-60% by weight of a gelling agent;
15-60% by weight of an aerosol-forming material;
1 to 10% by weight of active substance;
and the second aerosol-generating material comprises an amorphous solid, the amorphous solid comprising:
30-60% by weight of a gelling agent;
10-40% by weight of an aerosol-forming material;
20-50% by weight of a flavoring agent;
, where these weights are calculated on a dry weight basis,
The amorphous solid of the first aerosol-generating material has a different composition than the amorphous solid of the second aerosol-generating material.

In a further embodiment, consumables for use in non-combustion aerosol delivery devices are provided. This consumable is
a support;
a first aerosol-generating material attached to a support;
a second aerosol-generating material attached to the support;
and each of the first and second aerosol-generating materials comprises an amorphous solid, the amorphous solid comprising:
30-60% by weight of a gelling agent;
15-60% by weight of an aerosol-forming material;
0-60% by weight of at least one of nicotine, a flavorant and an acid, the acid having a boiling point ranging from 100°C to 350°C and/or a PK ranging from 3 to 7 when measured at 25°C. having an acidic functional group with an _a value,
where these weights are calculated on a dry weight basis,
The amorphous solid of the first aerosol-generating material has a different composition than the amorphous solid of the second aerosol-generating material.

In a further embodiment, consumables for use in non-combustion aerosol delivery devices are provided. This consumable is
a support;
a first aerosol-generating material attached to a support;
a second aerosol-generating material attached to the support;
and each of the first and second aerosol-generating materials comprises an amorphous solid, the amorphous solid comprising:
30-60% by weight of a gelling agent;
15-60% by weight of an aerosol-forming material;
0-60% by weight of nicotine, a flavoring agent, and at least one of benzoic acid and/or lactic acid;
, where these weights are calculated on a dry weight basis,
The amorphous solid of the first aerosol-generating material has a different composition than the amorphous solid of the second aerosol-generating material.

Exemplary non-limiting formulations of four aerosol-generating materials with amorphous solids that can be included in the consumables of the present invention are provided in the table below.

definition
delivery system
As used herein, the term "delivery system" is intended to encompass systems that deliver a substance to a user,
Combustion-type aerosol delivery systems, such as cigarettes, cigarillos, cigars, and tobacco for pipe or hand-rolled or handmade cigarettes (based on tobacco, tobacco derivatives, puffed tobacco, reconstituted tobacco, tobacco substitutes or other smoking materials) regardless of),
Non-combustion aerosol delivery systems that release a compound from an aerosol-generating material without combusting the aerosol-generating material, e.g., electronic cigarettes, tobacco heating products, and hybrid systems that generate an aerosol using a combination of aerosol-generating materials, and Aerosol-free delivery systems that deliver at least one substance (with or without nicotine) to a user orally, nasally, transdermally, or otherwise without forming an aerosol. (including, but not limited to, lozenges, gums, patches, articles with inhalable powders, and oral products such as oral tobacco, which includes snus or wet snuff)
including.

Non-Combustion Aerosol Delivery Systems According to the present disclosure, a “non-combustion” aerosol delivery system is one in which the constituent aerosol-generating materials (or components thereof) of the aerosol delivery system facilitate delivery of at least one substance to a user. It is combusted or not burnt.

In some embodiments, the delivery system is a non-combustion aerosol delivery system, eg, a powdered non-combustion aerosol delivery system.

In some embodiments, the non-combustion aerosol delivery system is an electronic cigarette, also known as an electronic smoking device or electronic nicotine delivery system (END), although the presence of nicotine in the aerosol-generating material is not a requirement. Please note.

In some embodiments, the non-combustion aerosol delivery system is an aerosol-generating material heating system, also known as a non-combustion heating system. One example of such a system is a tobacco heating system.

In some embodiments, the non-combustion aerosol delivery system is a hybrid system that produces aerosol using a combination of aerosol-forming materials, one or more of which may be heated. Each of the aerosol-generating materials may, for example, be in the form of a solid, liquid, or gel, and may or may not contain nicotine. In some embodiments, a hybrid system comprises a liquid or gel aerosol-forming material and a solid aerosol-forming material. Solid aerosol-forming materials may comprise, for example, tobacco or non-tobacco products.

Typically, a non-combustion aerosol delivery system may comprise a non-combustion aerosol delivery device and consumables for use with the non-combustion aerosol delivery device.

In some embodiments, the present disclosure relates to a consumable comprising an aerosol-generating material and configured for use with a non-combustion aerosol delivery device. These consumables are sometimes referred to as articles throughout this disclosure.

In some embodiments, a non-combustion aerosol delivery system, eg, a non-combustion aerosol delivery device thereof, may comprise a power source and a controller. The power source may be, for example, a power source or a heat source. In some embodiments, the heat generating power source comprises a carbon substrate that may be energized to distribute power in the form of heat to the aerosol-generating material, or a heat transfer material proximate to the heat generating power source.

In some embodiments, a non-combustion aerosol delivery system may comprise a consumable receiving area, an aerosol generator, an aerosol generating area, a housing, a mouthpiece, a filter and/or an aerosol modifier.

In some embodiments, consumables used with non-combustion aerosol delivery devices include aerosol-generating materials, aerosol-generating material storage regions, aerosol-generating material transfer components, aerosol generators, aerosol-generating regions, housings, paper wrappers, filters. , a mouthpiece, and/or an aerosol modifier.

Active Agents In some embodiments, the delivered agent comprises an active agent.

An active agent, as used herein, is a bioactive material, ie, a material for achieving or enhancing a physiological response. Active substances may be selected from, for example, functional foods, nootropics, and psychoactive substances. The active substance may be naturally occurring or synthetically obtained. Active substances may comprise, for example, nicotine, caffeine, taurine, theine, vitamins (B6, B12, C, etc.), melatonin, cannabinoids, or components, derivatives or combinations thereof. The active substance may comprise one or more components, derivatives or extracts of tobacco, cannabis or other botanical materials.

In some embodiments, the active agent comprises nicotine. In some embodiments, the active agent comprises caffeine, melatonin or vitamin B12.

In some embodiments, the active agent is cannabidiol (CBD), tetrahydrocannabinol (THC), tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabinol (CBN), cannabigerol (CBG) ), cannabichromene (CBC), cannabicyclol (CBL), cannabivarin (CBV), tetrahydrocannabivarin (THCV), cannabidivarin (CBDV), cannabichromevarin (CBCV), cannabigerovarin (CBGV), cannabis navigerol monomethyl ether (CBGM) and one or more cannabinoid compounds selected from the group consisting of cannabinoid (CBE), cannabicitran (CBT).

The active substance may comprise one or more cannabinoid compounds selected from the group consisting of cannabidiol (CBD) and THC (tetrahydrocannabinol).

The active substance may comprise cannabidiol (CBD).

Active substances may comprise nicotine and cannabidiol (CBD).

Active substances may comprise nicotine, cannabidiol (CBD) and THC (tetrahydrocannabinol).

Botanical Materials As described herein, an active agent may comprise or be derived from one or more botanical materials or components, derivatives or extracts thereof. As used herein, the term "botanical material" includes any material derived from plants, including, but not limited to, extracts, leaves, bark, fibers, stems, roots. , seeds, flowers, fruits, pollen, shells, skins, etc. Alternatively, the material may comprise active compounds naturally occurring in plant material or obtained synthetically. The material may be in the form of liquids, gases, solids, powders, dusts, crushed particles, granules, pellets, pieces, strips, sheets, and the like. Examples of botanical materials are tobacco, eucalyptus, star anise, hemp, cocoa, cannabis, fennel, lemongrass, peppermint, spearmint, rooibos, chamomile, flax, ginger, ginkgo biloba extract, hazel, hibiscus, bay leaf, licorice, matcha. , mate, orange peel, papaya, rose, sage, tea (green tea, black tea, etc.), thyme, cloves, cinnamon, coffee, aniseed, basil, bay leaf, cardamom, coriander, cumin, nutmeg, oregano, paprika, rose Marie, Saffron, Lavender, Lemon Peel, Mint, Juniper, Elderflower, Vanilla, Wintergreen, Perilla, Turmeric, Turmeric, Sandalwood, Cilantro, Bergamot, Orange Blossom, Myrtle, Cassis, Valerian, Pimento, Mace, Damian , marjoram, olive, lemon balm, lemon basil, chives, carvi, verbena, tarragon, geranium, mulberry, ginseng, theanine, theacrine, maca, ashwagandha, damiana, guarana, chlorophyll, baobab, or any combination thereof. Mint is of the following mint varieties: Mentha arvensis, Grapefruit mint (Mentha c.v.), Egyptian mint (Mentha niliaca), Peppermint (Mentha piperita), Lime mint (Mentha piperita citrata c.v.). , chocolate mint (Mentha piperita c.v.), curly mint (Mentha spicata crispa), wild mint (Mentha cordifolia), horse mint (Mentha longifolia), pineapple mint (Mentha suaveolens variegata), pennyroyal mint (Mentha pulegium), It may be selected from English spearmint (Mentha spicata c.v.), and apple mint (Mentha suaveolens).

In some embodiments, the active substance comprises or is derived from one or more botanical substances or components, derivatives or extracts thereof, wherein the botanical substance is tobacco.

In some embodiments, the active substance comprises or is derived from one or more botanical substances or components, derivatives or extracts thereof, wherein the botanical substances are selected from eucalyptus, star anise, cocoa, and hemp. be done.

In some embodiments, the active substance comprises or is derived from one or more botanical substances or components, derivatives or extracts thereof, wherein the botanical substances are selected from rooibos and fennel.

Perfume In some embodiments, the substance to be delivered comprises a perfume.

As used herein, the terms "perfume" and "flavourant" are used to create a desired taste, aroma, or other somatosensory sensation in products intended for adult consumers where local regulations permit. refers to materials that can They may be naturally occurring flavoring materials, botanical materials, extracts of botanical materials, synthetically obtained materials, or combinations thereof (e.g., tobacco, cannabis, licorice, hydrangea, eugenol, magnolia leaves, chamomile, Fenugreek, clove, maple, matcha, menthol, Japanese mint, anise, cinnamon, turmeric, Indian spice, Asian spice, herb, wintergreen, cherry, berry, red berry, cranberry, peach, apple, orange, mango. , Clementine, Lemon, Lime, Tropical Fruits, Papaya, Rhubarb, Grape, Durian, Dragon Fruit, Cucumber, Blueberry, Mulberry, Citrus, Drambuie, Bourbon, Scotch, Whiskey, Gin, Tequila, Rum, Spearmint, Peppermint , Lavender, Aloe Vera, Cardamom, Celery, Cascarilla, Nutmeg, Sandalwood, Bergamot, Geranium, Khat, Naswar, Betel, Shisha, Pine, Honey Essence, Rose Oil, Vanilla, Lemon oil, orange oil, orange blossom, cherry blossom, cassia, caraway, cognac, jasmine, ylang ylang, sage, fennel, wasabi, pepper, ginger, coriander, coffee, hemp, from any variety of the mint genus. mint oil, eucalyptus, star anise, cocoa, lemongrass, rooibos, flax, ginkgo biloba, hazel, hibiscus, laurel, mate, orange peel, rose, tea (green tea, black tea, etc.), thyme, juniper, elderflower, basil , bay leaf, cumin, oregano, paprika, rosemary, saffron, lemon peel, mint, shiso, curcuma, cilantro, myrtle, cassis, valerian, pimento, mace, damian, marjoram, olive, lemon balm, lemon basil, chives, carvi, verbena, tarragon, limonene, thymol, camphene), flavor enhancers, bitter receptor site blockers, sensory receptor site activators or stimulants, sugars and/or sugar substitutes (e.g., sucralose, acesulfame potassium, aspartame, saccharin, cyclamate, lactose, sucrose, glucose, fructose, sorbitol, or mannitol), as well as other additives such as charcoal, Chlorophyll, minerals, botanicals, or breath fresheners may be included. They may be imitation, synthetic or natural ingredients or blends thereof. They can be in any suitable form, such as liquids (such as oils), solids (such as powders), or gases.

In some embodiments, the flavoring comprises menthol, spearmint, and/or peppermint. In some embodiments, the flavorant comprises cucumber, blueberry, citrus fruit, and/or redberry flavor components. In some embodiments, the perfume comprises eugenol. In some embodiments, the flavorant comprises flavor components extracted from tobacco. In some embodiments, the flavorant comprises flavor components extracted from cannabis.

In some embodiments, the flavorant is a somatosensory sensation that is usually chemically induced and perceived by stimulating the fifth cranial nerve (trigeminal nerve) in addition to or instead of the olfactory or gustatory nerves. sensates intended to achieve the, and these may include agents that provide heating, cooling, stinging, and numbing effects. A suitable thermal effect agent may be, but is not limited to, vanillyl ethyl ether, and suitable cooling agents include, but are not limited to, eucalyptol and WS-3. may be

Aerosol-Generating Materials Aerosol-generating materials are materials capable of generating an aerosol when energized, for example, by heating, irradiation, or in any other way. Aerosol-generating materials may, for example, be in the form of solids, liquids, or gels, and may or may not contain active agents and/or flavorants. In some embodiments, the aerosol-generating material may comprise an "amorphous solid", which may alternatively be referred to as a "monolithic solid" (ie, non-fibrous). In some embodiments, the amorphous solid may be a dry gel. Amorphous solids are solid materials that can hold some fluid, such as a liquid, within them. In some embodiments, the aerosol-generating material is, for example, from about 50%, 60%, or 70% by weight amorphous solids to about 90%, 95%, or 100% by weight amorphous solids. It may comprise a solid.

Aerosol-forming materials may comprise one or more active agents and/or fragrances, one or more aerosol-forming materials, and optionally one or more other functional materials.

Aerosol-Forming Materials Aerosol-forming materials may comprise one or more components capable of forming an aerosol. In some embodiments, the aerosol-forming material is glycerin, glycerol, propylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, 1,3-butylene glycol, erythritol, meso-erythritol, ethyl vanillate, ethyl laurate, One or more of diethyl suberate, triethyl citrate, triacetin, diacetin mixture, benzyl benzoate, benzyl phenyl acetate, tributyrin, lauryl acetate, lauric acid, myristic acid, and propylene carbonate.

In some embodiments, the aerosol forming agent is one or more polyhydric alcohols such as propylene glycol, triethylene glycol, 1,3-butanediol, and glycerin, esters of polyhydric alcohols such as glycerol mono- , di- or triacetates, and/or aliphatic esters of mono-, di- or polycarboxylic acids such as dimethyldodecanedioate and dimethyltetradecanedioate.

Functional Materials The one or more other functional materials may comprise one or more of pH modifiers, colorants, preservatives, binders, fillers, stabilizers, and/or antioxidants. .

A substrate material may be present on or in a support to form a substrate. The support may be or comprise, for example, paper, card, cardboard, cardboard, recycled material, plastic material, ceramic material, composite material, glass, metal, or metal alloy. In some embodiments the support comprises a susceptor. In some embodiments, the susceptor is embedded within the material. In some alternative embodiments, the susceptor is on one or both sides of the material.

Consumables Consumables are articles that comprise or consist of an aerosol-generating material that is intended to be partially or wholly consumed during use by a user. A consumable may comprise one or more other components, such as an aerosol-generating material storage region, an aerosol-generating material transfer component, an aerosol-generating region, a housing, a paper wrapper, a mouthpiece, a filter, and/or an aerosol modifier. . The consumable may also comprise an aerosol generator, eg, a heater that generates heat to cause generation of an aerosol from the aerosol-generating material when in use. The heater may comprise, for example, a combustible material, a material heatable by electrical conduction, or a susceptor.

Susceptor A susceptor is a material that can be heated by the impingement of a varying magnetic field, eg an alternating magnetic field. The susceptor may be an electrically conductive material, in which case its penetration with a varying magnetic field causes inductive heating of the heating material. The heating material may be a magnetic material, in which case its penetration with a varying magnetic field causes magnetic hysteresis heating of the heating material. The susceptor may be both electrically conductive and magnetic, in which case the susceptor is heatable by both heating mechanisms. A device configured to generate a varying magnetic field is referred to herein as a magnetic field generator.

Aerosol Modifiers Aerosol modifiers are configured to modify the aerosol produced, for example by altering the taste, aroma, acidity, or another characteristic of the aerosol, typically in the aerosol-generating region. Substance placed downstream. The aerosol modifier may be provided in an aerosol modifier release component operable to selectively release the aerosol modifier.

Aerosol modifiers can be, for example, additives or adsorbents. Aerosol modifiers may comprise, for example, one or more of flavorants, colorants, water, and carbon adsorbents. Aerosol modifiers can be, for example, solids, liquids, or gels. Aerosol modifiers may be in powder, thread, or granular form. Aerosol modifiers may be free of filtration materials.

Aerosol Generator An aerosol generator is a device configured to cause the generation of an aerosol from an aerosol-generating material. In some embodiments, the aerosol generator is a heater configured to subject the aerosol-generating material to thermal energy to release one or more volatiles from the aerosol-generating material to form an aerosol. In some embodiments, the aerosol generator is configured to cause generation of aerosol from the aerosol-generating material without heating. For example, the aerosol generator may be configured to subject the aerosol-generating material to one or more of vibration, high pressure, or electrostatic energy.

Claims (29)

A consumable for use with a non-combustion aerosol delivery device, said consumable comprising:
a first aerosol-generating material;
a second aerosol-generating material;
wherein each of said first and second aerosol-generating materials comprises an amorphous solid, said amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein the weights are calculated on a dry weight basis and the amorphous solids of the first aerosol-generating material differ in composition from the amorphous solids of the second aerosol-generating material A consumable, having a composition. 2. The consumable of claim 1, wherein said amorphous solid of said first aerosol-generating material comprises said active agent and said amorphous solid of said second aerosol-generating material comprises said flavorant. . 3. The consumable of claim 1 or claim 2, wherein said amorphous solid of said first aerosol-generating material is free of said flavorant and said acid. A consumable according to any preceding claim, wherein said amorphous solid of said second aerosol-generating material is free of said active agent and said acid. 4. Any one of claims 1-3, wherein the amorphous solid of the first aerosol-generating material comprises the active agent and the amorphous solid of the second aerosol-generating material comprises the acid. Consumables listed in section. 6. The consumable of claim 5, wherein said amorphous solid of said first aerosol-generating material is free of said acid and said flavorant. 7. The consumable of claim 5 or claim 6, wherein said amorphous solid of said second aerosol-generating material is free of said flavorant and said active agent. 2. The consumable of claim 1, wherein said amorphous solid of said first aerosol-generating material comprises said flavorant and said amorphous solid of said second aerosol-generating material comprises said acid. 9. The consumable of claim 8, wherein said amorphous solid of said first aerosol-generating material is free of said active agent and said acid. 10. The consumable of claim 8 or claim 9, wherein said amorphous solid of said second aerosol-generating material is free of said flavorant and said active agent. the first aerosol-generating material comprising:
0.5 to 60% by weight of a gelling agent;
5-80% by weight of an aerosol-forming material;
and is free of actives, flavors and acids,
said second aerosol-generating material comprises 0.1-60% by weight of at least one of an active agent, a flavorant and an acid;
2. The consumable of claim 1, wherein these weights are calculated on a dry weight basis. 2. The active agent in the amorphous solid of the first aerosol-generating material is present in an amount different from the amount of the active agent in the amorphous solid of the second aerosol-generating material. 12. The consumable according to any one of 11. 13. The active agent in the amorphous solid of the first aerosol-generating material is present in an amount less than the amount of the active agent in the amorphous solid of the second aerosol-generating material. Consumables described in . wherein said amorphous solid of said first aerosol-generating material comprises from 0 to 10% by weight of said active substance present therein; and said amorphous solid of said second aerosol-generating material comprises therein 14. A consumable according to claim 13, comprising 10-60% by weight of said active substance present. 1, 2, 4, 5, wherein said amorphous solid of said first aerosol-generating material comprises a flavorant different from said flavorant of said amorphous solid of said second aerosol-generating material; 15. The consumable according to any one of 8, 9 or 12-14. Claims 1-3, 5, 6, wherein said amorphous solid of said first aerosol-generating material comprises an active substance different from said active substance of said amorphous solid of said second aerosol-generating material, 15. Consumables according to any one of 8 or 12-14. A consumable according to any one of the preceding claims, wherein said consumable comprises a support and said first and second aerosol-generating materials are attached to said support. 18. The consumable according to claim 17, wherein said support is a flat support. a third aerosol-generating material comprising an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein these weights are calculated on a dry weight basis and said amorphous solids of said third aerosol-generating material are less than said first aerosol-generating material and/or said second aerosol-generating material A consumable according to any one of the preceding claims, having a composition different from that of said amorphous solid. a fourth aerosol-generating material comprising an amorphous solid, the amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0-60% by weight of at least one of an active substance, a flavoring agent and an acid;
wherein the weights are calculated on a dry weight basis and the amorphous solids of the fourth aerosol-generating material are at least one of the first, second, or third aerosol-generating materials 20. The consumable of claim 19, having a composition different from that of one said amorphous solid. said amorphous solid of said first aerosol-generating material comprises said active agent and is free of said flavorant and said acid;
said amorphous solid of said second aerosol-generating material comprises said flavorant and is free of said active agent and said acid;
said amorphous solid of said third aerosol-generating material comprises said acid and is free of said flavorant and said active agent;
21. The consumable of claim 20, wherein said amorphous solid of said fourth aerosol-generating material is free of said active agent, said flavorant and said acid. When said amorphous solid comprises an acid,
Claim 1- wherein said acid has a boiling point in the range of 100°C to 350°C and/or said acid has an acidic functional group with _a PKa value in the range of 3 to 7 when measured at 25°C 22. The consumable according to any one of Clauses 21. A consumable according to any preceding claim, wherein when said amorphous solid comprises an acid, said acid is an organic acid. A consumable according to any one of the preceding claims, wherein when said amorphous solid comprises an acid, said acid is lactic acid and/or benzoic acid. 25. The consumable according to claim 24, wherein said acid is lactic acid. A non-combustion aerosol delivery system comprising a consumable according to any one of claims 1 to 25 and a non-combustion aerosol delivery device, wherein the non-combustion aerosol delivery device comprises the consumable A non-combustion aerosol delivery system comprising an aerosol generating device arranged to generate an aerosol from the consumable when used with the non-combustion aerosol delivery device. A method of manufacturing a consumable for use with a non-combustion aerosol delivery device, comprising:
providing a support;
depositing on said support at least two separate portions of a slurry comprising a gelling agent, an aerosol-forming material and at least one of an active agent, a flavorant and an acid;
drying the at least two separate portions of the slurry to obtain a first aerosol-generating material and a second aerosol-generating material, the first and second aerosol-generating materials being applied to the support; is attached and
wherein each of said first and second aerosol-generating materials comprises an amorphous solid, said amorphous solid comprising:
0.5 to 60% by weight of a gelling agent;
0-80% by weight of an aerosol-forming material;
0 to 60% by weight of at least one of an active agent, a flavorant and an acid, wherein the weights are calculated on a dry weight basis, and the amorphous solid of the first aerosol-generating material; has a composition different from the composition of said amorphous solids of said second aerosol-generating material;
forming the consumable;
How to prepare. A method according to claim 27, wherein the consumable is according to any one of claims 1-25. Use of the consumable according to any one of claims 1 to 25 in a non-combustion aerosol delivery device, wherein said consumable is used with said non-combustion aerosol delivery device: A use arranged to generate an aerosol from said consumable.

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