JP2023131816A - Control device and coelomic fluid processing system - Google Patents

Abstract

To provide an ascites treatment system which can calculate the protein concentration of ascites.SOLUTION: An ascites treatment system 1 comprises: a concentrator 12 which concentrates ascites; a first liquid supply line 16 which supplies the ascites to the concentrator 12; a second liquid supply line 17 which discharges the ascites concentrated by the concentrator 12; a pressure measurement device 20 which measures the in-line pressure of the first liquid supply line 16; a liquid discharge line 18 which discharges drainage removed by the concentrator 12; and a control device 21. The control device 21 includes a calculation unit 61 which calculates the protein concentration in the ascites on the basis of the in-line pressure measured by the pressure measurement device 20.SELECTED DRAWING: Figure 1

Description

The present invention relates to a control device and a body cavity fluid treatment system.

As a treatment for ascites, which is a type of body cavity fluid, ascites is removed from the patient, pathogenic substances such as bacteria and cancer cells are removed from the ascites, and it is concentrated while retaining useful components such as albumin. There is a method called Cell-free and Concentrated Ascites Reinfusion Therapy, which returns ascites to the body.

Ascites treatment systems are commonly used in such treatments. This ascites treatment system uses an ascites bag, a filter, a concentrator, and a concentrated ascites bag connected in this order, and filters and concentrates the ascites by flowing it with a pump or head. Separation membranes such as hollow fiber membranes are used in filters and concentrators.

When ascites is passed through the membrane of a filter or concentrator in the ascites treatment system described above, substances that cannot pass through the membrane may accumulate on the surface or inside the membrane, making it difficult for ascites to pass through the membrane. be. This state is expressed as the membrane being clogged. If you try to pass ascites when the membrane is clogged, the pressure inside the filter or concentrator will increase, which may cause damage to the membrane or leakage of ascites from the connection. Therefore, as shown in Patent Document 1, for example, a device has been proposed that has a function of monitoring the pressure applied to the filter and cleaning the filter when the pressure increases.

JP 2019-13487 Publication

By the way, in existing ascites treatment systems, the viscosity of the ascites being treated and the concentration of substances in the ascites are not recognized, so ascites is treated at the same flow rate (flow rate) regardless of the viscosity of the ascites, etc. Sometimes. In such a case, if the flow rate of ascites is too high relative to the viscosity of the ascites being treated, the pressure applied to the concentrator will quickly rise and it may be determined that the membrane is clogged. On the other hand, if the flow rate of ascites is too low relative to the viscosity of ascites, the concentration process may take too long, or the ascites may not be sufficiently concentrated and the concentrated ascites may not reach the desired concentration.

Furthermore, before treatment, the concentration of substances in ascites may be measured using a measuring device separate from the ascites treatment system, and settings such as the flow rate required for treatment may be determined. In that case, if the flow rate is changed midway through, the concentration of the finished concentrated ascites needs to be measured again. It takes a lot of time and effort to carry out such density measurement, and therefore, as described above, the process is often performed without recognizing the density.

The present invention has been made in view of the above, and an object of the present invention is to provide a control device and a body cavity fluid treatment system that can grasp either the physical properties of body cavity fluid such as ascites fluid or the concentration of substances in body cavity fluid. .

As a result of extensive studies, the present inventors have determined that the control device of the body cavity fluid treatment system calculates at least one parameter of the physical properties of the body cavity fluid or the substance concentration in the body cavity fluid based on the internal pressure of the fluid delivery line. The inventors have discovered that the above problem can be solved by providing a function, and have completed the present invention.

That is, the present invention includes the following aspects.
(1) a concentrator for concentrating body cavity fluid; a first liquid supply line for supplying body cavity fluid to the concentrator; and a second fluid supply line for discharging body cavity fluid concentrated in the concentrator; Measuring the internal pressure of at least one of the drain line that discharges the waste liquid removed by the concentrator, the first liquid feed line, the second liquid feed line, and the drain line. A control device for controlling a body cavity fluid treatment system comprising at least a pressure measuring device, the control device controlling a body cavity fluid treatment system comprising: a pressure measuring device; A control device comprising a calculation unit that calculates at least one of the parameters.
(2) The control according to (1), wherein the calculation unit calculates the parameter based on a relational expression indicating a relationship between the line pressure and the parameter, and the line pressure measured by the pressure measuring device. Device.
(3) Controlling the flow rate of body cavity fluid in at least one of the first liquid feeding line, the second liquid feeding line, and the drainage line based on the parameters calculated by the calculation unit. The control device according to (1) or (2), further comprising a flow rate control section.
(4) The control device according to (3), wherein the flow rate control unit is configured to change the concentration rate of body cavity fluid in the concentrator based on the parameter.
(5) The control device according to any one of (1) to (4), further comprising a parameter display section that displays the parameters calculated by the calculation section.
(6) The method according to any one of (1) to (5), further comprising a recommended settings calculation unit that calculates recommended settings for body cavity fluid treatment setting items based on the parameters calculated by the calculation unit. Control device.
(7) The control device according to (6), further comprising a recommended settings display unit that displays the recommended settings calculated by the recommended settings calculation unit.
(8) The control device according to (6) or (7), further comprising a setting section that sets the setting items in the recommended settings calculated by the recommended settings calculation section.
(9) the physical property of the body cavity fluid is viscosity;
The control device according to any one of (1) to (8), wherein the substance concentration in the body cavity fluid is a protein concentration.
(10) A body cavity fluid treatment system comprising the control device according to any one of (1) to (9).

According to the present invention, it is possible to provide a control device and a body cavity fluid processing system that can calculate at least either the physical properties of body cavity fluid or the substance concentration in body cavity fluid.

FIG. 1 is an explanatory diagram schematically showing the configuration of an ascites treatment system. FIG. 2 is a block diagram showing the configuration of a control device. It is a graph showing a relational expression between line pressure and protein concentration in ascites. FIG. 3 is a diagram showing the correspondence between the protein concentration in ascites and the appropriate flow rate of concentrated ascites. FIG. 3 is a block diagram showing another configuration of the control device. FIG. 3 is a diagram showing an example of a display of a parameter display section. FIG. 3 is a block diagram showing another configuration of the control device. FIG. 3 is a diagram illustrating an example of a display of a recommended setting display section. FIG. 3 is a block diagram showing another configuration of the control device. It is an explanatory view showing the outline of other compositions of an ascites treatment system.

Hereinafter, an example of a preferred embodiment of the present invention will be described with reference to the drawings. Note that the positional relationships such as top, bottom, left, and right in this specification are based on the positional relationships shown in the drawings, unless otherwise specified.

FIG. 1 is an explanatory diagram schematically showing the configuration of an ascites treatment system 1 as a body cavity fluid treatment system according to the present embodiment.

The ascites treatment system 1 includes an ascites bag 10 as a body cavity fluid storage unit, a filter 11, a concentrator 12, a concentrated ascites bag 13 as a concentrated body cavity fluid storage unit, a liquid supply line 15, and a first supply line. It includes a liquid line 16, a second liquid feeding line 17, a liquid drain line 18, a liquid feeding means 19, a pressure measuring device 20, a control device 21, and the like.

The ascites bag 10 is, for example, a flexible bag, and can contain ascites collected from a patient.

The filter 11 has, for example, a cylindrical housing. The filter 11 has liquid passage ports 11a, 11b at both ends in the longitudinal direction (vertical direction), and two liquid passage ports 11c, 11d on the side surfaces.

The filter 11 includes a filtration membrane 30 such as a hollow fiber membrane that removes predetermined pathogenic substances such as bacteria and cancer cells, and allows predetermined useful components such as albumin to pass through. The inner region of the filtration membrane 30 (the inner region of the hollow fiber membrane) communicates with the liquid passage ports 11a and 11b, and the outer region of the filtration membrane 30 (the outer region of the hollow fiber membrane) communicates with the liquid passage ports 11c and 11d. Note that in this embodiment, the liquid passage ports 11b and 11c are closed.

The concentrator 12 has, for example, a cylindrical housing. The concentrator 12 has liquid passage ports 12a, 12b at both ends in the longitudinal direction (vertical direction), and two liquid passage ports 12c, 12d on the side surfaces.

The concentrator 12 is equipped with a concentrating membrane 40 such as a hollow fiber membrane that removes and condenses water from ascites, for example. The inner region of the concentration membrane 40 communicates with the liquid passage ports 12a and 12b, and the outer region of the concentration membrane 40 communicates with the liquid passage ports 12c and 12d. Note that in this embodiment, the liquid passage port 12d is closed.

The concentrated ascites bag 13 is, for example, a flexible bag, and can accommodate concentrated ascites concentrated in the concentrator 12. The concentrated ascites bag 13 is installed at a lower position than the ascites bag 10.

The liquid feeding line 15 is connected to the ascites bag 10 and the filter 11. The upstream end of the liquid feeding line 15 is connected to the ascites bag 10, and the downstream end of the liquid feeding line 15 is connected to the liquid passage port 11a of the filter 11. In addition, in this specification, "upstream side" refers to the upstream side when ascites flows through the filter 11 and the concentrator 12 in this order.

The first liquid feeding line 16 is connected to the filter 11 and the concentrator 12 . The upstream end of the first liquid feeding line 16 is connected to the liquid passing port 11d of the filter 11, and the downstream end of the first liquid feeding line 16 is connected to the liquid passing port 12b of the concentrator 12. It is connected to the.

The second liquid feeding line 17 is connected to the concentrator 12 and the concentrated ascites bag 13. The upstream end of the second liquid feeding line 17 is connected to the liquid passage port 12a of the concentrator 12, and the downstream end of the second liquid feeding line 17 is connected to the concentrated ascites bag 13. There is.

A drain line 18 is connected from the concentrator 12 to an external drain. The upstream end of the drain line 18 is connected to the liquid passage port 12c of the concentrator 12. Note that, for example, flexible tubes are used for the lines 15 to 18.

The liquid feeding means 19 passes the ascites in the ascites bag 10 through the liquid feeding line 15, the filter 11, the first liquid feeding line 16, the concentrator 12, and the second liquid feeding line 17 in this order to the concentrated ascites bag 13. It has the function of sending liquid. For example, the liquid feeding means 19 includes a first pump 50 provided in the first liquid feeding line 16 and a second pump 51 provided in the second liquid feeding line 17.

The first pump 50 is, for example, a tube pump, and can pump ascites by handling the tube of the first liquid feeding line 16. Further, the first pump 50 can close the first liquid feeding line 16 when stopped.

The second pump 51 is, for example, a tube pump, and can pump ascites by handling the tube of the second liquid feeding line 17. Further, the second pump 51 can close the second liquid feeding line 17 when stopped.

The pressure measuring device 20 has a function of measuring the line pressure of the first liquid feeding line 16. For example, the pressure measuring device 20 includes a pressure sensor communicating with a drip chamber 55 connected to, for example, the first liquid feeding line 16.

The control device 21 is, for example, a computer having a CPU, memory, and the like. The control device 21 can perform ascites treatment by controlling the operation of each device such as the first pump 50 and the second pump 51. The control device 21 can implement ascites treatment by, for example, executing a program stored in a memory using a CPU.

The control device 21 also includes a storage section 60, a calculation section 61, and a flow rate control section 62, as shown in FIG.

The storage unit 60 stores a relational expression R1 defining the relationship between the protein concentration N as a substance concentration in ascites, which is a parameter as shown in FIG. 3, and the line pressure P of the first liquid feeding line 16, and Relationship data R2 indicating the correspondence between the protein concentration N and the appropriate concentrated ascites flow rate in the second liquid feeding line 17 is stored. The relational data R2 includes an upper limit threshold Nt and a lower limit threshold Nu of the protein concentration corresponding to the range of the appropriate concentrated ascites flow rate.

The calculation unit 61 calculates the protein concentration n1 in ascites based on the relational expression R1 and the in-line pressure p1 measured by the pressure measuring device 20. The proteins in ascites whose concentration is calculated are, for example, albumin and globulin.

The flow rate control unit 62 controls the flow rate of concentrated ascites (concentrated ascites flow rate) based on the protein concentration n1 calculated by the calculation unit 61 and the relational data R2. Concentrated ascites is ascites that is concentrated in the concentrator 12 and discharged through the second liquid feeding line 17. In this embodiment, the flow rate of concentrated ascites corresponds to the flow rate of the second pump 51, so the flow rate control unit 62 adjusts the flow rate of the second pump 51 to control the flow rate of concentrated ascites.

The control device 21 in FIG. 1 has a physical configuration including, for example, a control unit including a CPU (Central Processing Unit) and a memory, an operation section, a display, a speaker, a storage unit, a communication unit, and the like. When the CPU executes a predetermined program stored in the memory, each function of the storage section 60, calculation section 61, flow rate control section 62, etc. is realized.

Next, the flow rate control of concentrated ascites performed by the control device 21 in this embodiment will be explained together with the ascites treatment process performed by the ascites treatment system 1.

The storage unit 60 of the control device 21 stores a relational expression R1 and relational data R2 in advance. The relational expression R1 and the relational data R2 are input into the input section of the control device 21 by a user, or input from outside the control device 21 through a communication network, and stored in the storage section 60, for example.

At the time of treating ascites, first, as shown in FIG. 1, an ascites bag 10 containing ascites collected from a patient is connected to a liquid supply line 15. Then, the first pump 50 and the second pump 51 are activated, and ascites filtration/concentration processing is started.

At this time, ascites in the ascites bag 10 is sent to the filter 11 through the liquid feed line 15. Ascites flows into the inner region of the filtration membrane 30 from the liquid passage port 11a of the filter 11, passes through the filtration membrane 30, and flows out to the outer region of the filtration membrane 30. At this time, certain pathogenic substances are removed from ascites.

The ascites that has flowed out into the outer region of the filter membrane 30 flows out from the liquid passage port 11d of the filter 11 into the first liquid feeding line 16, and is sent to the concentrator 12 through the first liquid feeding line 16. Ascites flows into the inner region of the concentrating membrane 40 through the liquid passage port 12b of the concentrator 12, and is discharged from the liquid passage port 12a. At this time, a part of the ascites, mainly water, passes through the concentrating membrane 40 and flows out to an area outside the concentrating membrane 40. This mainly removes water from the ascites and concentrates it. The ascites concentrated in the concentrator 12 passes through the second liquid supply line 17 and is stored in the concentrated ascites bag 13.

On the other hand, the waste liquid removed by the concentrator 12 is discharged to the outside through a drain line 18. The above-mentioned filtration and ascites treatment are performed, for example, until all the ascites in the ascites bag 10 is treated, and when all the ascites in the ascites bag 10 is treated, the first pump 50 and the second pump 51 are stopped, A series of ascites treatments are completed.

Here, the flow rate at which ascites that has passed through the filter 11 flows into the concentrator 12 is defined as the "ascites inflow flow rate", the flow rate of concentrated ascites flowing from the concentrator 12 into the concentrated ascites bag 13 is defined as the "concentrated ascites flow rate", and the flow rate in the concentrator 12 is defined as the "ascites inflow flow rate". If the flow rate of the drained liquid discharged from 12 to the drain line 18 is defined as the "drained liquid flow rate", the following equation holds true.
Ascites inflow flow rate (mL/min) = concentrated ascites flow rate (mL/min) + drainage fluid flow rate (mL/min)

The concentrated ascites fluid will eventually be re-injected intravenously into the patient, so a small amount is preferable. Therefore, it is desired to reduce the flow rate of concentrated ascites, but when the flow rate of concentrated ascites decreases, the flow rate of drainage fluid increases according to the above formula. In this case, the amount of water removed in the concentrator 12 increases, and if such water removal continues, the concentration membrane 40 inside the concentrator 12 is likely to become clogged. Therefore, the concentrated ascites flow rate is set to an appropriate flow rate as follows.

For example, during the filtration/concentration process of ascites, the pressure measuring device 20 measures the line pressure p1 in the first liquid feeding line 16. The measurement result of the line pressure p1 is output to the control device 21. In the control device 21, the calculation unit 61 substitutes the line pressure p1 measured by the pressure measurement device 20 into a relational expression R1 as shown in FIG. 3, and calculates the protein concentration n1 in ascites. The pressure value p1 substituted into the relational expression R1 at this time may be a pressure value at a certain moment, or may be an average value of pressure values over a certain period of time.

Next, the flow rate control unit 62 controls the flow rate of concentrated ascites based on the protein concentration n1 in ascites. For example, the flow rate of the second pump 51 is adjusted based on the protein concentration n1 in ascites and relational data R2 as shown in FIG. For example, when the protein concentration n1 in ascites is higher than the upper threshold (20 g/dL in FIG. 4), the flow rate of the second pump 51 is reduced, and when it is lower than the lower threshold (10 g/dL in FIG. 4), increases the flow rate of the second pump 51. Moreover, when the protein concentration n1 in ascites is below the upper limit threshold and above the lower limit threshold, the flow rate of the second pump 51 is maintained. Note that in this example, the flow rate of the second pump 51 was adjusted while maintaining the flow rate of the first pump 50, but the first pump 50 may also be adjusted, or the first pump 50 may be adjusted. Both pump 50 and second pump 51 may be regulated.

Note that the upper and lower thresholds are not necessarily determined by the user; for example, the control device 21 automatically determines the upper and lower thresholds within a certain range based on the desired protein concentration set by the user. Good too. In this case, concentrated ascites with a protein concentration close to that desired by the user can be obtained. In some cases, the upper threshold and the lower threshold may be the same value.

The flow rate of concentrated ascites may be controlled by the flow rate control section 62 during a part of the period during the filtration/concentration process. For example, when each line 15 to 18, filter 11, and concentrator 12 are filled with saline as at the start of treatment, the protein concentration of ascites cannot be calculated accurately, so the flow rate of concentrated ascites is controlled by the flow rate controller 62. It is better not to implement such controls. Further, the control of the flow rate of concentrated ascites may be stopped when an alarm occurs due to an abnormality or when the user determines that automatic control is unnecessary.

According to the present embodiment, since the control device 21 includes the calculation unit 61 that calculates the protein concentration in ascites based on the in-line pressure measured by the pressure measurement device 20, the protein concentration in the ascites to be treated is determined. It is possible to realize ascites treatment according to the situation. As a result, for example, ascites can be treated at an appropriate flow rate, so that ascites treatment time can be shortened and the amount of ascites treated can be increased. Furthermore, ascites can be concentrated to a desired concentration.

The calculation unit 61 calculates the protein concentration n1 of ascites based on a relational expression R1 indicating the relationship between the line pressure P and the ascites protein concentration N, and the line pressure p1 measured by the pressure measuring device 20. Thereby, the protein concentration of ascites can be suitably calculated.

The control device 21 includes a flow rate control unit 62 that controls the flow rate of concentrated ascites concentrated in the concentrator 12 based on the protein concentration in ascites calculated by the calculation unit 61. Thereby, for example, the flow rate of concentrated ascites can be automatically controlled based on the protein concentration in ascites, and the user does not have to make detailed changes to the settings.

The flow rate control unit 62 is configured to reduce the flow rate of ascites when the protein concentration in ascites exceeds a predetermined upper limit threshold, and to increase the flow rate of ascites when the protein concentration in ascites is lower than a predetermined lower limit threshold. ing. Therefore, an appropriate flow rate of concentrated ascites can be achieved by simple control.

The control device 21 may further include a parameter display section 80 that displays the protein concentration in ascites, which is a parameter calculated by the calculation section 61, as shown in FIG. The parameter display section 80 has a display (display screen) 81 as shown in FIG. 6, and displays, for example, the protein concentration in ascites numerically. In such a case, information on the protein concentration in ascites is provided to the user, and the user can make various settings for ascites treatment, for example, by referring to this information. At this time, in addition to numerically displaying the protein concentration in ascites at a certain moment during processing, the total amount of protein in concentrated ascites can be displayed by integrating the instantaneous protein concentration values. The average concentration of concentrated ascites can also be displayed by calculating the time average of the protein concentration.

As shown in FIG. 7, the control device 21 includes a recommended setting calculation unit 90 that calculates recommended settings for ascites treatment setting items based on the protein concentration in ascites, which is a parameter calculated by the calculation unit 61, and a recommended setting calculation unit 90 that calculates recommended settings for ascites treatment setting items. The computer may further include a recommended settings display section 91 that displays recommended settings calculated by the calculation section 90.

The recommended setting calculation unit 90 calculates recommended settings such as setting items for ascites treatment, such as the flow rate of the first pump 50 and the second pump 51, the concentration rate of ascites, and the amount of concentrated ascites. For example, as described above, the flow rate of the second pump 51 (concentrated ascites flow rate) is calculated as the recommended setting using the correspondence relationship and relational expression between the ascites protein concentration calculated by the calculation unit 61 and the appropriate concentrated ascites flow rate. It's okay.

The recommended setting display unit 91 includes a display (display screen) 100 as shown in FIG. 8, and displays calculated recommended settings for various setting items on the display 100. In such a case, the recommended setting value may be displayed numerically, or, for example, "the recommended setting is ○○" may be displayed in text. In this case, the user can appropriately and easily set the setting items based on the recommended settings.

The control device 21 may include a recommended setting calculating section 90 and a setting section 92 that sets setting items in the recommended settings calculated by the recommended setting calculating section 90, as shown in FIG.

The setting unit 92 changes various setting items for ascites treatment to the recommended settings calculated by the recommended setting calculation unit 90, such as the flow rate of the first pump 50 and the second pump 51, the concentration rate of ascites, and the amount of concentrated ascites. . In this case, since the setting items are automatically set to the recommended settings, the burden on the user can be reduced.

Although preferred embodiments of the present invention have been described above with reference to the accompanying drawings, the present invention is not limited to such examples. It is clear that those skilled in the art can come up with various changes or modifications within the scope of the idea described in the claims, and these naturally fall within the technical scope of the present invention. It is understood that

The configuration of the ascites treatment system 1 is not limited to that of the above embodiment. For example, if the ascites treatment system 1 is capable of filtering and concentrating ascites, the way the lines 15 to 18, the filter 11, and the concentrator 12 are connected to each other, the arrangement of the pumps 50 and 51, etc. may have different configurations. It's okay. For example, the second pump 51 may be provided in the drain line 18. In such a case, the flow rate control unit 62 controls the flow rate of concentrated ascites by adjusting the flow rate of at least one of the first pump 50 of the first liquid feeding line 16 and the second pump 51 of the drainage line 18. It's okay. In addition, by providing a pump in each of the first liquid feeding line 16, second liquid feeding line 17, and drainage line 18, and adjusting the flow rate of any one of these pumps, the flow rate of concentrated ascites can be controlled. It's okay.

In the above embodiment, the flow rate control unit 62 controlled the flow rate of the second liquid feeding line 17 based on the protein concentration calculated by the calculation unit 61, but the flow rate of the first liquid feeding line 16, The flow rate of body cavity fluid in at least one of the second liquid feeding line 17 and the liquid drainage line 18 may be controlled.

For example, the flow rate control unit 62 may adjust the concentration rate of the body cavity fluid in the concentrator 12 based on the protein concentration calculated by the calculation unit 61. The concentration rate is the rate of concentration, and is expressed as (concentrated ascites flow rate)/(ascites inflow flow rate) x 100 (%). Specifically, when the protein concentration in the ascites calculated by the calculation unit 61 exceeds a predetermined upper limit threshold, the flow rate control unit 62 controls the flow rate in the first liquid feeding line 16 so that the protein concentration decreases. At least the flow rate of the body cavity fluid flowing into the concentrator 12, the flow rate of the body cavity fluid flowing out from the concentrator 12 in the second liquid feeding line 17, and the flow rate of the waste fluid removed from the concentrator 12 in the drainage line 18. Adjust either. Further, the flow rate control unit 62 controls the flow rate to the concentrator 12 in the first liquid feeding line 16 so that when the protein concentration in ascites calculated by the calculation unit 61 is lower than a predetermined lower limit threshold, the protein concentration increases. Adjust at least one of the following: the flow rate of the body cavity fluid flowing out from the concentrator 12 in the second liquid feeding line 17, and the flow rate of the waste fluid removed from the concentrator 12 in the drainage line 18. .

The pressure measuring device 20 was used to measure the line pressure in the first liquid feeding line 16, but as shown in FIG. Alternatively, the pressure within both the first liquid feeding line 16 and the second liquid feeding line 17 may be measured. When measuring the line pressures of both the first liquid feeding line 16 and the second liquid feeding line 17, the difference between the two measured pressure values is calculated from the line for calculating the protein concentration in ascites. It may also be used as the internal pressure p1. The pressure measuring device 20 may further measure the pressure inside the drain line 18. The pressure measuring device 20 measures at least one of the line pressure in the first liquid feeding line 16, the line pressure in the second liquid feeding line 17, and the line pressure in the draining line 18. It's okay.

The relational expression R1 for calculating the protein concentration in ascites, which is a parameter, and the relational data R2 for calculating the appropriate concentrated ascites flow rate may be updated one after another. In such a case, the results of the filtration and concentration processing performed in the ascites treatment system 1 may be reflected in the relational expression R1 and the relational data R2, or the relationship may be calculated from data obtained from outside the ascites treatment system 1 via the communication network. The formula R1 and the relational data R2 may be updated.

The correspondence relationship between the parameter protein concentration in ascites and the appropriate concentrated ascites flow rate does not need to be the relational data R2, and may be a relational expression or the like.

For example, in the above embodiment, the ascites treatment system 1 filters and concentrates the ascites in the ascites bag 10 and stores it in the concentrated ascites bag 13. It may be filtered or concentrated. In this case, a puncture needle may be connected to the tip of the liquid feeding line 15. Furthermore, although the ascites treatment system 1 stores filtered and concentrated concentrated ascites in the concentrated ascites bag 13, the ascites treatment system 1 may directly return the concentrated ascites to the patient through the second liquid feeding line 17. In this case, a puncture needle may be connected to the tip of the second liquid feeding line 17.

Furthermore, the ascites treatment system 1 may not include the filter 11. In such a case, the ascites treatment system 1 may concentrate already filtered ascites using the concentrator 12.

The control device 21 may be a part of the ascites treatment system 1 or may be a separate device. For example, the control device 21 may be located at a location separate from the ascites treatment system 1 and connected to the ascites treatment system 1 via a communication network or the like.

In the above embodiment, the parameter calculated by the calculation unit 61 was the protein concentration in ascites, but it may be the concentration of another substance in ascites. Further, the parameter may be at least one of the physical properties of ascites and the concentration of substances in ascites, and may be the physical properties of ascites, such as the viscosity and specific gravity of ascites. The calculation unit 61 may calculate parameters for both the physical properties of ascites and the substance concentration in ascites.

Further, the ascites treatment system 1 may use a head instead of a pump to transport ascites. In such a case, the ascites treatment system 1 may be configured so that the heights of the ascites bag 10 and the concentrated ascites bag 13 can be changed as appropriate.

Although the above embodiment is an example in which the present invention is applied to an ascites treatment system 1 for treating ascites, the present invention can also be applied to a body cavity fluid treatment system for treating other body cavity fluids such as pleural effusion. .

INDUSTRIAL APPLICABILITY The present invention is useful in providing a control device and a body cavity fluid processing system that can calculate at least either the physical properties of body cavity fluid or the concentration of a substance in body cavity fluid.

1 Ascites treatment system 10 Ascites bag 11 Filter 12 Concentrator 13 Concentrated ascites bag 15 Liquid feeding line 16 First liquid feeding line 17 Second liquid feeding line 18 Drainage line 19 Liquid feeding means 20 Pressure measuring device 21 Control device 61 Calculation part

Claims (10)

a concentrator for concentrating body cavity fluid;
a first liquid sending line that sends body cavity fluid to the concentrator;
a second liquid feeding line that discharges the body cavity fluid concentrated in the concentrator;
a drain line for discharging the waste liquid removed by the concentrator;
A control device that controls a body cavity fluid treatment system, including at least a pressure measuring device that measures the internal pressure of at least one of the first liquid feeding line, the second liquid feeding line, and the drainage line. And,
A control device comprising: a calculation unit that calculates at least one parameter of physical properties of the body cavity fluid or substance concentration in the body cavity fluid based on the line pressure measured by the pressure measuring device. The control device according to claim 1, wherein the calculation unit calculates the parameter based on a relational expression indicating a relationship between the line pressure and the parameter, and the line pressure measured by the pressure measuring device. a flow rate control unit that controls the flow rate of body cavity fluid in at least one of the first liquid feeding line, the second liquid feeding line, and the liquid drainage line based on the parameters calculated by the calculation unit; The control device according to claim 1 or 2, further comprising: The control device according to claim 3, wherein the flow rate control unit is configured to adjust a concentration rate of body cavity fluid in the concentrator based on the parameter. The control device according to any one of claims 1 to 4, further comprising a parameter display unit that displays the parameters calculated by the calculation unit. The control device according to any one of claims 1 to 5, further comprising a recommended settings calculation unit that calculates recommended settings for setting items for body cavity fluid treatment based on the parameters calculated by the calculation unit. The control device according to claim 6, further comprising a recommended setting display unit that displays the recommended settings calculated by the recommended setting calculation unit. The control device according to claim 6 or 7, further comprising a setting section that sets the setting items to the recommended settings calculated by the recommended settings calculation section. The physical property of the body cavity fluid is viscosity,
The control device according to any one of claims 1 to 8, wherein the substance concentration in the body cavity fluid is a protein concentration. A body cavity fluid treatment system comprising the control device according to any one of claims 1 to 9.

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