JP2023103597A - Medical molding composed of polyethylene naphthalate resin composition - Google Patents

Abstract

To provide a medical molding composed of a polyethylene naphthalate resin composition having excellent transparency and heat resistance.SOLUTION: A medical molding composed of a polyethylene naphthalate resin composition includes, based on (A) a polyethylene naphthalate resin (A component) 100 pts.wt., (B) a polyether imide resin (B component) 30-220 pts.wt.SELECTED DRAWING: None

Description

TECHNICAL FIELD The present invention relates to a molded article for medical use comprising a polyethylene naphthalate resin composition having excellent transparency and heat resistance.

Compared to polyethylene terephthalate resin, polyethylene naphthalate resin has a slower crystallization speed in a static environment, so it is characterized by the ability to easily obtain a transparent molded product by injection molding. It is used in transparent moldings for food applications. However, since polyethylene naphthalate resin has a low glass transition temperature of 125° C., it is thermally deformed by autoclave sterilization, and its application to medical moldings has been limited.

As for improving the heat resistance of polyethylene naphthalate resin, Patent Document 1 discloses a method for producing a copolymerized polyester having a glass transition temperature of 135° C. or higher by copolymerizing naphthalenedicarboxylic acid and an aromatic diol component. However, although the glass transition temperature of the polyethylene naphthalate resin increases by copolymerizing a specific amount of the aromatic diol component, the glass transition temperature reached is 138°C or less, and the copolymerization is carried out in the temperature range of 120°C to 134°C. Due to heat deformation due to autoclave sterilization, the heat resistance is insufficient. Patent Document 2 discloses a non-crosslinkable polyester resin obtained by copolymerizing naphthalene dicarboxylic acid with a component derived from isosorbide. It is possible to increase the glass transition temperature to 150° C. or higher by copolymerizing a certain amount or more of a component derived from isosorbide, but the disclosed copolymerized polyester is dark brown and insufficient in transparency. Patent Document 3 discloses a method for preventing fluorescence of a polyalkylene naphthalate resin, which comprises adding a polyetherimide resin to the polyalkylene naphthalate resin. Further, Patent Document 4 discloses a photographic film base comprising a blend of polyethylene naphthalate resin and polyetherimide resin, but none of them are verified for transparency and heat resistance.

JP 2014-25022 A JP 2018-177942 A JP-A-10-101916 JP-A-9-179242

An object of the present invention is to provide a molded article for medical use comprising a polyethylene naphthalate resin composition having excellent transparency and heat resistance.

The present inventors have made intensive studies to achieve the above object, and have found that a polyethylene naphthalate resin composition having excellent transparency and heat resistance is obtained by adding a specific amount of a polyetherimide resin to a polyethylene naphthalate resin. The inventors have found that a molded article for medical use can be obtained, and have solved the above problems.

That is, the subject of the present invention is a polyethylene characterized by containing 30 to 220 parts by weight of (B) a polyetherimide resin (B component) with respect to 100 parts by weight of (A) a polyethylene naphthalate resin (A component). This is achieved by a medical molding made of a naphthalate resin composition.

INDUSTRIAL APPLICABILITY According to the present invention, it is possible to provide a molded article for medical use comprising a polyethylene naphthalate resin composition having excellent transparency and heat resistance. etc. can be suitably used.

Further details of the present invention will be described below.

<About A component>
The polyethylene naphthalate resin, which is component A of the present invention, is produced using a dicarboxylic acid component mainly composed of naphthalenedicarboxylic acid and/or an ester-forming derivative of naphthalenedicarboxylic acid, and a glycol component mainly composed of ethylene glycol. can be done.

As the naphthalenedicarboxylic acid component, 2,6-naphthalenedicarboxylic acid and 2,7-naphthalenedicarboxylic acid are used as main components, but other dicarboxylic acids may be used in combination as long as the properties are not impaired. Other dicarboxylic acids include, for example, terephthalic acid, isophthalic acid, 4,4'-diphenyldicarboxylic acid, diphenoxyethane-4,4'-dicarboxylic acid, diphenylsulfone-4,4'-dicarboxylic acid, diphenyl ether-4, Aromatic dicarboxylic acids such as 4'-dicarboxylic acid, adipic acid, sebacic acid, succinic acid, aliphatic dicarboxylic acids such as oxalic acid, alicyclic dicarboxylic acids such as cyclohexanedicarboxylic acid, and the like, one or Two or more kinds may be used, and can be arbitrarily selected depending on the purpose. The amount of the other dicarboxylic acid used is preferably 30 mol % or less, more preferably 20 mol % or less, based on the total acid components. As the ester-forming derivative of naphthalenedicarboxylic acid, dimethyl 2,6-naphthalenedicarboxylate and dimethyl 2,7-naphthalenedicarboxylate are used as main components, but esters of other dicarboxylic acids are used as long as the properties are not impaired. Formable derivatives can be used in combination. Other ester-forming derivatives of dicarboxylic acids include, for example, terephthalic acid, isophthalic acid, 4,4'-diphenyldicarboxylic acid, diphenoxyethane-4,4'-dicarboxylic acid, diphenylsulfone-4,4'-dicarboxylic acid. acids, lower dialkyl esters of aromatic dicarboxylic acids such as diphenyl ether-4,4′-dicarboxylic acid, lower dialkyl esters of alicyclic dicarboxylic acids such as cyclohexanedicarboxylic acid, adipic acid, sebacic acid, succinic acid, oxalic acid, etc. Lower dialkyl esters of aliphatic dicarboxylic acids and the like can be mentioned, and one or more of these may be used and can be arbitrarily selected depending on the purpose. The amount of other ester-forming derivative of dicarboxylic acid to be used is preferably 30 mol % or less, more preferably 20 mol % or less, relative to the total dicarboxylic acid ester-forming derivative component.

Also, a small amount of a tri- or higher functional carboxylic acid component such as trimellitic acid may be used, and a small amount of an acid anhydride such as trimellitic anhydride may be used. In addition, a small amount of hydroxycarboxylic acid such as lactic acid and glycolic acid or an alkyl ester thereof may be used, and can be arbitrarily selected depending on the purpose.

As the glycol component, ethylene glycol is used as the main component, but other glycol components can be used together as long as the properties are not impaired. Other glycol components include, for example, 1,4-butanediol, 1,3-propylene glycol, 1,2-propylene glycol, neopentylene glycol, hexamethylene glycol, decamethylene glycol, cyclohexanedimethanol, diethylene glycol, and triethylene. One or two or more of alkylene glycols such as glycol, poly(oxy)ethylene glycol, poly(oxy)tetramethylene glycol, poly(oxy)methylene glycol, etc. may be used, and can be arbitrarily selected depending on the purpose. In addition, small amounts of polyhydric alcohol components such as glycerin may be used. A small amount of epoxy compound may also be used. The amount of other glycol components used is preferably 30 mol % or less, more preferably 20 mol % or less, based on the total glycol components.

Said polyethylene naphthalate resin can be manufactured by a conventionally well-known manufacturing method. That is, a direct esterification method in which a dicarboxylic acid component and a diol component are directly reacted to distill off water and esterify, followed by polycondensation under reduced pressure, or a dicarboxylic acid dimethyl ester and a diol component are reacted to form methyl alcohol. is distilled off, transesterified, and then polycondensed under reduced pressure. Solid state polymerization can be carried out to further increase the intrinsic viscosity.

It is preferable to use a catalyst and a stabilizer during the above transesterification, esterification and polycondensation reactions. Mg compounds, Mn compounds, Ca compounds, Zn compounds and the like are used as transesterification catalysts, and examples thereof include acetates, monocarboxylates, alcoholates and oxides thereof. The esterification reaction can be carried out using only a dicarboxylic acid and a diol without adding a catalyst, but it can also be carried out in the presence of a polycondensation catalyst, which will be described later. As polycondensation catalysts, Ge compounds, Ti compounds, Sb compounds, etc. can be used, and examples thereof include germanium dioxide, germanium hydroxide, germanium alcoholates, titanium tetrabutoxide, titanium tetraisopropoxide, and titanium oxalate. . Phosphorus compounds are preferably used as stabilizers. Preferred phosphorus compounds include phosphoric acid and its esters, phosphorous acid and its esters, and hypophosphorous acid and its esters. Further, during the esterification reaction, a tertiary amine such as triethylamine, a quaternary ammonium hydroxide such as tetraethylammonium hydroxide, and a basic compound such as sodium carbonate can be added in order to suppress diethylene glycol by-production. Various stabilizers and modifiers can be added to the obtained polyester resin.

The intrinsic viscosity of component A is preferably 0.5 to 1.0 dl/g, more preferably 0.55 to 0.85 dl/g, still more preferably 0.60 to 0.68 dl/g. . If the intrinsic viscosity of component A is less than 0.5 dl/g, the impact resistance may be poor. Sometimes.

<About B component>
The polyetherimide resin, which is the component B of the present invention, is a resin containing a cyclic imide structure, and is not particularly limited as long as it can be used for the purpose of the present invention. Polyetherimide resins containing imide groups as repeating units are preferred. Further, structural units other than cyclic imide and ether units, such as aromatic and aliphatic ester units, oxycarbonyl units, etc., may be contained in the main chain of the polyimide as long as the effects of the present invention are not impaired.

Specific examples of polyetherimide resins that can be preferably used in the present invention include polyetherimide resins represented by the following formula (1).

(In formula (1), n is an integer of 2 or more, R ₁ is a divalent aromatic or aliphatic group containing 6 to 30 carbon atoms, R ₂ is 6 to 30 carbon atoms, , alkylene groups with 2 to 20 carbon atoms, cycloalkylene groups with 2 to 20 carbon atoms, and alkylene groups with 2 to 8 carbon atoms. is a divalent organic group selected from the group consisting of polydiorganosiloxane groups selected from

Examples of R ₁ and R ₂ include aromatic residues and alkylene groups represented by the following formulas (2) to (8).

(In formula (8), n is an integer of 2 or more.)
In the present invention, a polyetherimide resin represented by the following formula (9) is preferable from the viewpoint of compatibility with polyethylene naphthalate resin.

(In formula (9), n is an integer of 2 or more.)
Examples of this polyetherimide resin include "ULTEM1010" manufactured by SHPP Japan LLC.

The content of component B is 30 to 220 parts by weight, preferably 45 to 180 parts by weight, more preferably 70 to 150 parts by weight, per 100 parts by weight of component A. If the content of component B is less than 30 parts by weight, heat resistance is not improved. On the other hand, when the content exceeds 220 parts by weight, the transparency is lowered.

(About other additives)
The resin composition of the present invention can contain various additives such as antioxidants and release agents within the scope of the present invention.

<Antioxidant>
The resin composition of the present invention may contain, as an antioxidant, at least one antioxidant selected from the group consisting of hindered phenol compounds, phosphite compounds, phosphonite compounds and thioether compounds. The addition of an antioxidant not only stabilizes the hue and fluidity during molding, but also has the effect of improving hydrolysis resistance.

Examples of hindered phenol compounds include α-tocopherol, butylhydroxytoluene, sinapyl alcohol, vitamin E, n-octadecyl-β-(4'-hydroxy-3',5'-di-tert-butylfer)propionate. , 2-tert-butyl-6-(3′-tert-butyl-5′-methyl-2′-hydroxybenzyl)-4-methylphenyl acrylate, 2,6-di-tert-butyl-4-(N, N-dimethylaminomethyl)phenol, 3,5-di-tert-butyl-4-hydroxybenzylphosphonate diethyl ester, 2,2'-methylenebis(4-methyl-6-tert-butylphenol), 2,2'-methylenebis (4-ethyl-6-tert-butylphenol), 4,4'-methylenebis(2,6-di-tert-butylphenol), 2,2'-methylenebis(4-methyl-6-cyclohexylphenol), 2,2 '-dimethylene-bis(6-α-methyl-benzyl-p-cresol) 2,2'-ethylidene-bis(4,6-di-tert-butylphenol), 2,2'-butylidene-bis(4-methyl -6-tert-butylphenol), 4,4′-butylidenebis(3-methyl-6-tert-butylphenol), triethylene glycol-N-bis-3-(3-tert-butyl-4-hydroxy-5-methyl phenyl)propionate, 1,6-hexanediol bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate], bis[2-tert-butyl-4-methyl 6-(3- tert-butyl-5-methyl-2-hydroxybenzyl)phenyl]terephthalate, 3,9-bis{2-[3-(3-tert-butyl-4-hydroxy-5-methylphenyl)propionyloxy]-1, 1,-dimethylethyl}-2,4,8,10-tetraoxaspiro[5,5]undecane, 4,4′-thiobis(6-tert-butyl-m-cresol), 4,4′-thiobis( 3-methyl-6-tert-butylphenol), 2,2′-thiobis(4-methyl-6-tert-butylphenol), bis(3,5-di-tert-butyl-4-hydroxybenzyl)sulfide, 4, 4′-di-thiobis(2,6-di-tert-butylphenol), 4,4′-tri-thiobis(2,6-di-tert-butylphenol), 2,2-thiodiethylenebis-[3-( 3,5-di-tert-butyl-4-hydroxyphenyl)propionate], 2,4-bis(n-octylthio)-6-(4-hydroxy-3′,5′-di-tert-butylanilino)-1 , 3,5-triazine, N,N′-hexamethylenebis-(3,5-di-tert-butyl-4-hydroxyhydrocinnamide), N,N′-bis[3-(3,5-di -tert-butyl-4-hydroxyphenyl)propionyl]hydrazine, 1,1,3-tris(2-methyl-4-hydroxy-5-tert-butylphenyl)butane, 1,3,5-trimethyl-2,4 ,6-tris(3,5-di-tert-butyl-4-hydroxybenzyl)benzene, tris(3,5-di-tert-butyl-4-hydroxyphenyl)isocyanurate, tris(3,5-di- tert-butyl-4-hydroxybenzyl)isocyanurate, 1,3,5-tris(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)isocyanurate, 1,3,5-tris-2[3 (3,5-di-tert-butyl-4-hydroxyphenyl)propionyloxy]ethyl isocyanurate and tetrakis[methylene-3-(3′,5′-di-tert-butyl-4-hydroxyphenyl)propionate] Methane etc. are illustrated. Among the above compounds, tetrakis[methylene-3-(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate]methane, octadecyl-3-(3,5-di-tert-butyl-4-hydroxyphenyl ) propionate, and 3,9-bis[2-{3-(3-tert-butyl-4-hydroxy-5-methylphenyl)propionyloxy}-1,1-dimethylethyl]-2,4,8,10 -tetraoxaspiro[5,5]undecane is preferably utilized. Octadecyl-3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate is particularly preferred. All of these are readily available. The above hindered phenol compounds can be used alone or in combination of two or more.

Phosphite compounds include triphenyl phosphite, tris(nonylphenyl) phosphite, tridecyl phosphite, trioctyl phosphite, trioctadecyl phosphite, didecyl monophenyl phosphite, dioctyl monophenyl phosphite, diisopropyl mono Phenylphosphite, monobutyldiphenylphosphite, monodecyldiphenylphosphite, monooctyldiphenylphosphite, tris(diethylphenyl)phosphite, tris(di-iso-propylphenyl)phosphite, tris(di-n-butylphenyl) ) phosphite, tris(2,4-di-tert-butylphenyl)phosphite, tris(2,6-di-tert-butylphenyl)phosphite, distearylpentaerythritol diphosphite, bis(2,4- di-tert-butylphenyl)pentaerythritol diphosphite, bis(2,6-di-tert-butyl-4-methylphenyl)pentaerythritol diphosphite, bis(2,6-di-tert-butyl-4- ethylphenyl)pentaerythritol diphosphite, bis{2,4-bis(1-methyl-1-phenylethyl)phenyl}pentaerythritol diphosphite, phenylbisphenol A pentaerythritol diphosphite, bis(nonylphenyl)pentaerythritol diphosphite, dicyclohexylpentaerythritol diphosphite, and the like. Furthermore, as other phosphite-based compounds, those having a cyclic structure that react with dihydric phenols can also be used. For example, 2,2′-methylenebis(4,6-di-tert-butylphenyl)(2,4-di-tert-butylphenyl)phosphite, 2,2′-methylenebis(4,6-di-tert- butylphenyl)(2-tert-butyl-4-methylphenyl)phosphite and 2,2-methylenebis(4,6-di-tert-butylphenyl)octylphosphite. Suitable phosphite compounds include distearylpentaerythritol diphosphite, bis(2,4-di-tert-butylphenyl)pentaerythritol diphosphite, bis(2,6-di-tert-butyl-4-methyl phenyl)pentaerythritol diphosphite and bis{2,4-bis(1-methyl-1-phenylethyl)phenyl}pentaerythritol diphosphite.

Also, for example, 2,4,8,10-tetra-t-butyl-6-[3-(3-methyl-4-hydroxy-5-t-butylphenyl)propoxy]dibenzo[d,f][1,3 , 2] dioxaphosphepine [commercially available as "Sumilizer GP" (manufactured by Sumitomo Chemical Co., Ltd.). ], 2,10-dimethyl-4,8-di-t-butyl-6-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propoxy]-12H-dibenzo[d,g] [1,3,2]dioxaphosphosine, 2,4,8,10-tetra-t-butyl-6-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propoxy]dibenzo [d,f][1,3,2]dioxaphosphepin, 2,4,8,10-tetra-t-pentyl-6-[3-(3,5-di-t-butyl-4- hydroxyphenyl)propoxy]-12-methyl-12H-dibenzo[d,g][1,3,2]dioxaphosphosine, 2,10-dimethyl-4,8-di-t-butyl-6-[3 -(3,5-di-t-butyl-4-hydroxyphenyl)propionyloxy]-12H-dibenzo[d,g][1,3,2]dioxaphosphosine, 2,4,8,10-tetra -t-pentyl-6-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propionyloxy]-12-methyl-12H-dibenzo[d,g][1,3,2]di Oxaphosphosine, 2,4,8,10-tetra-t-butyl-6-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propionyloxy]-dibenzo[d,f][ 1,3,2]dioxaphosphepine, 2,10-dimethyl-4,8-di-t-butyl-6-(3,5-di-t-butyl-4-hydroxybenzoyloxy)-12H- Dibenzo[d,g][1,3,2]dioxaphosphosine, 2,4,8,10-tetra-t-butyl-6-(3,5-di-t-butyl-4-hydroxybenzoyloxy )-12-methyl-12H-dibenzo[d,g][1,3,2]dioxaphosphosine, 2,10-dimethyl-4,8-di-t-butyl-6-[3-(3- methyl-4-hydroxy-5-t-butylphenyl)propoxy]-12H-dibenzo[d,g][1,3,2]dioxaphosphosine, 2,4,8,10-tetra-t-butyl- 6-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propoxy]-12H-dibenzo[d,g][1,3,2]dioxaphosphosine, 2,10-diethyl- 4,8-di-t-butyl-6-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propoxy]-12H-dibenzo[d,g][1,3,2]di Oxaphosphosine, 2,4,8,10-tetra-t-butyl-6-[2,2-dimethyl-3-(3-t-butyl-4-hydroxy-5-methylphenyl)propoxy]-dibenzo[ d,f][1,3,2]dioxaphosphepin and the like can be mentioned. All of these are readily available. The above phosphite compounds can be used alone or in combination of two or more.

Phosphonite compounds include tetrakis(2,4-di-tert-butylphenyl)-4,4'-biphenylenediphosphonite, tetrakis(2,4-di-tert-butylphenyl)-4,3'-biphenyl diphosphonite, tetrakis(2,4-di-tert-butylphenyl)-3,3'-biphenylenediphosphonite, tetrakis(2,6-di-tert-butylphenyl)-4,4'-biphenylenediphosphonite night, tetrakis(2,6-di-tert-butylphenyl)-4,3'-biphenylenediphosphonite, tetrakis(2,6-di-tert-butylphenyl)-3,3'-biphenylenediphosphonite, bis(2,4-di-tert-butylphenyl)-4-phenyl-phenylphosphonite, bis(2,4-di-tert-butylphenyl)-3-phenyl-phenylphosphonite, bis(2,6- Di-n-butylphenyl)-3-phenyl-phenylphosphonite, Bis(2,6-di-tert-butylphenyl)-4-phenyl-phenylphosphonite, Bis(2,6-di-tert-butylphenyl) )-3-phenyl-phenylphosphonite and the like. Tetrakis(di-tert-butylphenyl)-biphenylenediphosphonite, bis(di-tert-butylphenyl)-phenyl-phenylphosphonite are preferred, and tetrakis(2,4-di-tert-butylphenyl)-biphenylenediphosphonite Night, bis(2,4-di-tert-butylphenyl)-phenyl-phenylphosphonite is more preferred. Such a phosphonite-based compound can be used in combination with a phosphite-based compound having an aryl group substituted with two or more alkyl groups, and is therefore preferable. Tetrakis (2,4-di-tert-butylphenyl)-biphenylene diphosphonite is preferable as the phosphonite compound, and the stabilizer containing the phosphonite as a main component is Sandostab P-EPQ (trademark, manufactured by Clariant) and Irgafos. It is commercially available as P-EPQ (trademark, manufactured by CIBA SPECIALTY CHEMICALS) and any of them can be used. The above phosphonite compounds can be used alone or in combination of two or more.

Specific examples of thioether compounds include dilaurylthiodipropionate, ditridecylthiodipropionate, dimyristylthiodipropionate, distearylthiodipropionate, pentaerythritol-tetrakis(3-laurylthiopropionate), Pentaerythritol-tetrakis (3-dodecylthiopropionate), pentaerythritol-tetrakis (3-octadecylthiopropionate), pentaerythritol tetrakis (3-myristylthiopropionate), pentaerythritol-tetrakis (3-stearylthio propionate) and the like. The above thioether compounds can be used alone or in combination of two or more.

The content of the antioxidant is preferably 0.01 to 2 parts by weight, more preferably 0.03 to 1 part by weight, and still more preferably 0.05 to 0.5 parts by weight with respect to 100 parts by weight of component A. be. When the content of the antioxidant is less than 0.01 parts by weight, the antioxidant effect is insufficient, and not only the hue and fluidity during molding become unstable, but also the hydrolysis resistance may deteriorate. . On the other hand, if the content is more than 2 parts by weight, the reactive components derived from the antioxidant may rather deteriorate the hydrolysis resistance.

Further, it is preferable to use a combination of two or more of the hindered phenol-based compound, the phosphite-based compound, the phosphonite-based compound, and the thioether-based compound. By using a combination of two or more types of hindered phenol-based compounds and phosphite-based compounds, phosphonite-based compounds, and thioether-based compounds, a synergistic effect as a stabilizer is exhibited, resulting in better color and fluidity during molding. It is effective in stabilizing properties and improving hydrolysis resistance.

<Release agent>
The resin composition of the present invention can contain a release agent. Specific examples of release agents include fatty acids, fatty acid metal salts, oxyfatty acids, paraffins, low-molecular-weight polyolefins, fatty acid amides, alkylenebis fatty acid amides, aliphatic ketones, fatty acid partially saponified esters, fatty acid lower alcohol esters, and fatty acid polyvalents. Examples include alcohol esters, fatty acid polyglycol esters and modified silicones. By blending these, a molded article having excellent mechanical properties, moldability and heat resistance can be obtained.

Fatty acids preferably have 6 to 40 carbon atoms, and specific examples include oleic acid, stearic acid, lauric acid, hydroxystearic acid, behenic acid, arachidonic acid, linoleic acid, linolenic acid, ricinoleic acid, palmitic acid, and montan. Acids and mixtures thereof and the like. The fatty acid metal salt is preferably an alkali (earth) metal salt of a fatty acid having 6 to 40 carbon atoms, and specific examples include calcium stearate, sodium montanate, calcium montanate and the like.

Oxy fatty acids include 1,2-oxysteric acid and the like. As the paraffin, those having 18 or more carbon atoms are preferable, and examples thereof include liquid paraffin, natural paraffin, microcrystalline wax, and petrolactam.

Low-molecular-weight polyolefins preferably have a molecular weight of 5,000 or less, and specific examples include polyethylene wax, maleic acid-modified polyethylene wax, oxidized-type polyethylene wax, chlorinated polyethylene wax, and polypropylene wax.

As the fatty acid amide, those having 6 or more carbon atoms are preferable, and specific examples include oleic acid amide, erucic acid amide, and behenic acid amide.

The alkylenebis fatty acid amide preferably has 6 or more carbon atoms, and specific examples include methylenebisstearic acid amide, ethylenebisstearic acid amide, N,N-bis(2-hydroxyethyl)stearic acid amide and the like.

As the aliphatic ketone, those having 6 or more carbon atoms are preferable, and examples thereof include higher aliphatic ketones.

Partially saponified fatty acid esters include partially saponified montanic acid esters. Examples of fatty acid lower alcohol esters include stearates, oleates, linoleates, linolenates, adipates, behenates, arachidonates, montanates and isostearates.

Examples of fatty acid polyhydric alcohol esters include glycerol tristearate, glycerol distearate, glycerol monostearate, pentaerythritol tetrastearate, pentaerythritol tristearate, pentaerythritol dimilystate, and pentaerythritol. Toll monostearate, pentaerythritol adipate stearate, sorbitan monobehenate and the like. Examples of fatty acid polyglycol esters include polyethylene glycol fatty acid esters, polytrimethylene glycol fatty acid esters, polypropylene glycol fatty acid esters, and the like.

Modified silicones include polyether-modified silicones, higher fatty acid alkoxy-modified silicones, higher fatty acid-containing silicones, higher fatty acid ester-modified silicones, methacryl-modified silicones, and fluorine-modified silicones.

Of these, fatty acids, fatty acid metal salts, oxyfatty acids, fatty acid esters, partially saponified fatty acid esters, paraffins, low molecular weight polyolefins, fatty acid amides, and alkylenebis fatty acid amides are preferred, and partially saponified fatty acid esters and alkylenebis fatty acid amides are more preferred. Among them, montanic acid ester, partially saponified montanic acid ester, polyethylene wax, acid value polyethylene wax, sorbitan fatty acid ester, erucic acid amide, and ethylenebisstearic acid amide are preferred, and partially saponified montanic acid ester and ethylenebisstearic acid amide are particularly preferred. .

The release agent may be used alone or in combination of two or more. The content of the release agent is preferably 0.01 to 3 parts by weight, more preferably 0.03 to 2 parts by weight, per 100 parts by weight of component A.

<Method for producing resin composition>
Any method may be employed to produce the resin composition of the present invention. For example, a method of premixing each component and optionally other components, followed by melt-kneading and pelletizing can be mentioned. Means for premixing include a Nauta mixer, a V-type blender, a Henschel mixer, a mechanochemical device, an extrusion mixer, and the like. In the pre-mixing, granulation can be performed by an extrusion granulator, a briquetting machine, or the like. After pre-mixing, the mixture is melt-kneaded by a melt-kneader typified by a vented twin-screw extruder, and pelletized by a device such as a pelletizer. Other examples of the melt-kneader include a Banbury mixer, a kneading roll, a constant temperature stirring vessel and the like, but a vented twin-screw extruder is preferred. Alternatively, each component and, optionally, other components may be supplied independently to a melt-kneader typified by a twin-screw extruder without being premixed.

<About the compact>
A molded article made of the resin composition of the present invention can be obtained by molding the pellets produced as described above. It is preferably obtained by injection molding or extrusion molding. In injection molding, not only ordinary molding methods, but also injection compression molding, injection press molding, gas-assisted injection molding, foam molding (including the method of injecting supercritical fluid), insert molding, in-mold coating molding, heat insulation metal Mold molding, rapid heating and cooling mold molding, two-color molding, multi-color molding, sandwich molding, ultra-high speed injection molding and the like can be mentioned. For molding, either cold runner method or hot runner method can be selected. The molded body has a container shape having a mouth portion serving as an opening, a body portion and a bottom portion. Molded bodies are preferred. In extrusion molding, it can also be used in the form of various profile extrusion moldings, sheets, films, and the like. In addition, the inflation method, calender method, casting method, and the like can be used for forming sheets and films. Furthermore, it is also possible to use the sheet-shaped molded body as a molded body that has been given a specific shape by vacuum forming or press molding.

[EXAMPLES] Hereafter, although the form which implements this invention is demonstrated by an Example, this invention is not limited to these. Moreover, evaluation of various physical properties was carried out by the following methods.

[Evaluation of Resin Composition]
(1) Transparency After drying the pellets obtained by the following method at 140 ° C. for 7 hours, an injection molding machine (EC130SXII-4Y manufactured by Toshiba Machine Co., Ltd.) was used with a cylinder temperature of 310 ° C. and a mold temperature of 90 ° C. A test piece having a length of 25 mm, a width of 50 mm, and a thickness of 1 mm was molded with a UV-visible spectrophotometer V-560 manufactured by JASCO Corporation, and the light transmittance at a wavelength of 450 nm was measured. The light transmittance should be 55% or more.
(2) Glass transition temperature Using pellets obtained by the following method, a differential scanning calorimeter (manufactured by TA Instruments Japan Co., Ltd.: DSC-2910) was used at a temperature increase rate of 20 ° C. / min. The glass transition temperature (Tg) was measured.
The glass transition temperature should be 140° C. or higher.

[Example 1-7, Comparative Example 1-2]
According to the contents shown in Table 1, the A component and the B component were supplied separately from the first supply port to a twin-screw extruder and melt-kneaded and extruded at a temperature of 310° C. to form pellets. Here, the first supply port is the root supply port. The twin-screw extruder used was a vented twin-screw extruder with a diameter of 30 mmΦ (manufactured by Japan Steel Works, Ltd.: TEX30α-31.5BW-2V).
The following materials were used in the examples and comparative examples of the present invention.

(A component)
AI: Polyethylene naphthalate resin obtained in Production Example I <Production Example I>
100 parts by weight of naphthalenedicarboxylic acid dimethyl ester and 51 parts by weight of ethylene glycol, 0.003 parts by weight (0.012 mmol) of cobalt acetate tetrahydrate, 0.014 parts by weight (0.08 mmol) of calcium acetate monohydrate and Using 0.044 parts by weight (0.0205 mmol) of manganese acetate tetrahydrate as a transesterification catalyst, transesterification was carried out by a conventional method, and 1.5 parts by weight (0.0205 mmol) of ethylene glycol 1% solution of amorphous germanium dioxide was obtained. 14 mmol) was added, and then 0.0057 parts by weight (0.41 mmol) of trimethyl phosphate was added to terminate the transesterification reaction. Solid phase polymerization was then carried out for 8 hours at a temperature of 227° C. and a degree of vacuum of 0.5 Torr to obtain a polyethylene naphthalate resin having an intrinsic viscosity of 0.60 dl/g.

(B component)
B-I: ULTEM1010 (trade name) manufactured by SHPP Japan LLC

<Examples 1 to 7>
Since the composition is within the scope of the claims, a molded article having excellent transparency and heat resistance could be obtained.

<Comparative Example 1>
Since the content of component B was less than the lower limit, heat resistance was not improved.
<Comparative Example 2>
Since the content of component B exceeded the upper limit, the result was poor transparency.

Claims (3)

(A) A medical treatment comprising a polyethylene naphthalate resin composition characterized by containing 30 to 220 parts by weight of (B) a polyetherimide resin (component B) with respect to 100 parts by weight of a polyethylene naphthalate resin (component A) Molded body for It is characterized by having a container shape having a mouth portion, a body portion, and a bottom portion serving as an opening, having a wall thickness of 0.5 to 2 mm at the center portion of the container, and having a light transmittance of 55% or more at a wavelength of 450 nm. The molded article for medical use according to claim 1. The molded article for medical use according to claim 1 or 2, which is a vial.