JP2023068217A - Electrocardiogram analyzer and control method for the same - Google Patents

Abstract

To provide an electrocardiogram analyzer capable of providing a function to assist diagnosis of arrhythmia, and a control method for the same.SOLUTION: An electrocardiogram analyzer has a function to generate synthetic electrocardiogram data related to induction that is not included in electrocardiogram data from the electrocardiogram data related to a plurality of inductions. The electrocardiogram analyzer outputs a trend display screen showing changes over time of a predetermined feature parameter with respect to induction included in the electrocardiogram data and induction included in the synthetic electrocardiogram data.SELECTED DRAWING: Figure 3

Description

(1) Date of distribution: February 5, 2021 Place of distribution: Document management system within Fukuda Denshi Co., Ltd. (This system is accessible only to related parties, After the distribution date, it became possible to distribute to third parties through parties who could access the system.) Publisher: Fukuda Denshi Co., Ltd. Contents of distribution: Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, PDF data file of the catalog of the product (SCM-9000) equipped with a trend display function for synthetic induction waveforms invented by Hironori Uchida (2) Sales date: March 26, 2021 Place of sale: Fukuda Denshi Hiroshima Sales Co., Ltd. Company Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. to Fukuda Denshi Hiroshima Sales Co., Ltd. Trends in synthetic induction waveforms invented by Yuki Fujiwara, Takafumi Goto, Mai Kobayashi, Hidenori Tsugawa, and Hironori Uchida A product (SCM-9000) equipped with a display function was sold. (3) Date of sale: March 29, 2021 Place of sale: Matsuyoshi Medical Instruments Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of items sold: Fukuda Denshi Co., Ltd., Matsuyoshi Medical Instruments Co., Ltd., Fujiwara We sold a product (SCM-9000) equipped with a trend display function for synthetic induced waveforms invented by Yuki, Takafumi Goto, Mai Kobayashi, Hidenori Tsugawa, and Hironori Uchida. (4) Date of sale: March 30, 2021 Location of sale: Fukuda Denshi South Tohoku Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. sells Fukuda Denshi South Tohoku Sales shares The company sold a product (SCM-9000) equipped with a trend display function for synthetic induction waveforms invented by Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, and Hironori Uchida.

(5) Date of sale: March 31, 2021 Place of sale: Fukuda Denshi Nantohoku Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of product sold: Fukuda Denshi Co., Ltd. sold to Fukuda Denshi South Tohoku Sales Co., Ltd. a product (SCM-9000) equipped with a trend display function for synthetic induction waveforms invented by Yuki Fujiwara, Takafumi Goto, Mai Kobayashi, Hidenori Tsugawa, and Hironori Uchida. . (6) Date of sale: March 31, 2021 Location of sale: Fukuda Denshi Minami Kanto Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. sells Fukuda Denshi Minami Kanto Sales shares The company sold a product (SCM-9000) equipped with a trend display function for synthetic induction waveforms invented by Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, and Hironori Uchida. (7) Date of sale: May 21, 2021 Place of sale: Fukuda Denshi Minami Kanto Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. sells Fukuda Denshi Minami Kanto Sales shares The company sold a product (SCM-9000) equipped with a trend display function for synthetic induction waveforms invented by Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, and Hironori Uchida. (8) Date of sale: June 24, 2021 Location of sale: Fukuda Denshi Seibu South Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. sells Fukuda Denshi Seibu South Sales shares The company sold a product (SCM-9000) equipped with a trend display function for synthetic induction waveforms invented by Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, and Hironori Uchida.

(9) Date of sale: July 20, 2021 Place of sale: Fukuda Denshi West Kanto Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sold item: Fukuda Denshi Co., Ltd. sold to Fukuda Denshi West Kanto Sales Co., Ltd. a product (SCM-9000) equipped with a trend display function for synthetic induction waveforms invented by Yuki Fujiwara, Takafumi Goto, Mai Kobayashi, Hidenori Tsugawa, and Hironori Uchida. . (10) Date of sale: July 28, 2021 Place of sale: Fukuda Denshi Hyogo Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. to Fukuda Denshi Hyogo Sales Co., Ltd. , Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, and Hironori Uchida equipped with a trend display function for synthetic induced waveforms (SCM-9000). (11) Date of sale: August 23, 2021 Place of sale: Fukuda Denshi Hokuriku Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. to Fukuda Denshi Hokuriku Sales Co., Ltd. , Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, and Hironori Uchida equipped with a trend display function for synthetic induced waveforms (SCM-9000). (12) Date of loan: August 25, 2021 Place of loan: Fukuda Denshi Keiji Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Details of loaned items: Fukuda Denshi Co., Ltd. to Fukuda Denshi Keiji Sales Co., Ltd. , Yuki Fujiwara, Takafumi Goto, Mai Kobayashi, Hidenori Tsugawa, and Hironori Uchida equipped with a trend display function for synthetic induction waveforms (SCM-9000).

(13) Date of loan: September 6, 2021 Place of loan: Fukuda Denshi Keiji Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Details of loaned item: Fukuda Denshi Co., Ltd. Ltd. lent to Fukuda Denshi Keiji Sales Co., Ltd. a product (SCM-9000) equipped with a trend display function for synthetic induction waveforms invented by Yuki Fujiwara, Takafumi Goto, Mai Kobayashi, Hidenori Tsugawa, and Hironori Uchida. (14) Date of sale: September 28, 2021 Location of sale: Fukuda Denshi Keiji Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. to Fukuda Denshi Keiji Sales Co., Ltd. , Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, and Hironori Uchida equipped with a trend display function for synthetic induced waveforms (SCM-9000). (15) Date of sale: September 29, 2021 Location of sale: Fukuda Denshi South Tohoku Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. sells Fukuda Denshi South Tohoku Sales shares The company sold a product (SCM-9000) equipped with a trend display function for synthetic induction waveforms invented by Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, and Hironori Uchida. (16) Date of sale: September 30, 3rd year of Reiwa Place of sale: Fukuda Denshi Keiji Sales Co., Ltd. Publisher: Fukuda Denshi Co., Ltd. Contents of sale: Fukuda Denshi Co., Ltd. to Fukuda Denshi Keiji Sales Co., Ltd. , Yuki Fujiwara, Takafumi Goto, Mayi Kobayashi, Hidenori Tsugawa, and Hironori Uchida equipped with a trend display function for synthetic induced waveforms (SCM-9000).

The present invention relates to an electrocardiogram analyzer and its control method.

In order to detect symptoms such as arrhythmia that are difficult to detect by short-term electrocardiogram measurement, long-term (typically 24-hour) electrocardiogram measurement is performed using a Holter electrocardiogram. An electrocardiogram measured by a Holter electrocardiograph is not uniform in quality and includes waveforms of tens of thousands of beats. Therefore, it is common for engineers and doctors to conduct various studies based on the results of automatic analysis by an electrocardiogram analyzer (Patent Documents 1 and 2).

JP 2009-95552 A JP 2020-130335 A

Long-term ECG is useful for diagnosing arrhythmias such as ischemic heart disease. For accurate diagnosis, it is desirable to measure an electrocardiogram of standard 12 leads or more. However, from the viewpoint of reducing the burden on the examinee during measurement in daily life, only a few Holter monitors can measure a standard 12-lead ECG, and ECGs related to 2-3 leads can be measured. Measurement is common.

The present invention has been made in view of such problems of the prior art, and one aspect of the present invention provides an electrocardiogram analysis apparatus capable of providing a function of assisting diagnosis of arrhythmia and a control method thereof.

The above objects are provided by acquisition means for acquiring electrocardiogram data related to a plurality of leads, generating means for generating synthetic electrocardiogram data related to leads not included in the electrocardiogram data from the electrocardiogram data, and combining the leads included in the electrocardiogram data. and output means for outputting a trend display screen showing temporal changes of predetermined characteristic parameters for leads included in the electrocardiogram data.

With such a configuration, according to the present invention, it is possible to provide an electrocardiogram analysis apparatus capable of providing a function of assisting diagnosis of arrhythmia, and a control method thereof.

1 is a block diagram showing a functional configuration example of a general-purpose computer as an example of an electrocardiogram analysis apparatus according to an embodiment of the present invention; FIG. 4 is a flow chart relating to the operation of the electrocardiogram analysis apparatus according to the embodiment; It is a figure which shows an example of the screen which the electrocardiogram analysis apparatus which concerns on embodiment presents.

The invention will now be described in detail on the basis of its exemplary embodiments with reference to the accompanying drawings. In addition, the following embodiments do not limit the invention according to the scope of claims. In addition, although a plurality of features are described in the embodiments, not all of them are essential to the invention, and the plurality of features may be combined arbitrarily. Furthermore, in the accompanying drawings, the same or similar configurations are denoted by the same reference numerals, and redundant description is omitted.

In the following embodiments, the case where the present invention is implemented by a general-purpose computer such as a personal computer or a tablet terminal will be described. However, the present invention can be implemented in any electronic device such as media players, smart phones, game consoles, and the like.

FIG. 1 is a block diagram showing a functional configuration example of a general-purpose computer 100 that can function as an electrocardiogram analysis apparatus according to this embodiment. The CPU 1 functioning as a control unit, for example, reads a program stored in the storage device 10 to the RAM 3 and executes it, thereby realizing a function according to the program. For example, the general-purpose computer 100 functions as an electrocardiogram analysis apparatus according to this embodiment by executing a specific application program (electrocardiogram analysis application) while the basic software (OS) is running on the general-purpose computer 100 .

The storage device 10 is, for example, a hard disk drive (HDD) or solid state drive (SSD), and stores basic software (OS), device drivers, applications, user data, and the like. The storage device 10 also stores GUI (graphical user interface) data for displaying menu screens and the like, user setting data, application initial setting data, and the like.

The ROM 2 stores programs, firmware, and various setting information necessary for starting the computer, such as a bootstrap loader. At least part of the ROM 2 may be rewritable.

The RAM 3 is used as an area for expanding programs executed by the CPU 1 and as a temporary storage area for variables, data, and the like. Also, part of the RAM 3 may be used as a video memory.

The memory card 4 is a recording medium that can be inserted into and removed from the card slot 5 , and the general-purpose computer 100 can read data from the memory card 4 inserted into the card slot 5 and write data to the memory card 4 . In this embodiment, the general-purpose computer 100 acquires data such as long-term electrocardiograms recorded by a Holter electrocardiograph through the memory card 4 . The general-purpose computer 100 may acquire electrocardiogram data to be automatically analyzed by other methods. For example, even if the electrocardiogram data to be automatically analyzed is acquired from the Holter electrocardiograph that performed the measurement or from another external device 200 that holds the measured electrocardiogram data, through communication through the communication interface 20, which will be described later. good.

The display unit 6 has a display device such as a liquid crystal display (LCD) or an organic EL display, a display control circuit, and the like. Although FIG. 1 shows a configuration in which the display unit 6 is built in the general-purpose computer 100, the display unit 6 may be externally attached. Also, both the built-in display unit 6 and the external display unit 6 may be included.

The operation unit 8 is a device for a user to input instructions to the general-purpose computer 100, and is typically one or more input devices such as a keyboard, pointing device (mouse, etc.), contact sensing device (touch panel, etc.). Note that the keyboard may be a hardware keyboard or a software keyboard. The touch panel may be provided on the display unit 6, or may be in the form of a touch pad that is commonly found in notebook computers.

A communication interface (I/F) 20 is hardware for the general-purpose computer 100 to communicate with an external device 200 according to a predetermined standard. The communication I/F 20 has a configuration corresponding to the supported communication standard, such as a connector conforming to the wired communication standard and a wireless transmitter/receiver conforming to the wireless communication standard. The communication I/F 20 may support multiple communication standards. The communication standards supported by the communication I/F 20 are not particularly limited, but Ethernet (registered trademark) and USB are wire communication standards, and Bluetooth (registered trademark) and wireless LAN (IEEE802.11x) are wireless communication standards. is a typical example.

A user (for example, a technician) who uses automatic analysis of an electrocardiogram measured by a Holter electrocardiograph activates an automatic analysis application stored in the storage device 10 by an operation method corresponding to the OS running on the general-purpose computer 100. . The CPU 1 reads the automatic analysis application from the storage device 10 to the RAM 3 and executes it, so that the general-purpose computer 100 functions as an electrocardiogram analysis device. The general-purpose computer 100 that functions as an electrocardiogram analysis device is hereinafter referred to as an electrocardiogram analysis device 100 .

Next, the operation of the electrocardiogram analysis apparatus 100 realized by the CPU 1 executing the automatic analysis application will be described using the flowchart shown in FIG. Here, as an example of a function for assisting diagnosis of arrhythmia, an operation for implementing trend display that visually presents chronological changes in characteristic parameters of an electrocardiogram will be described.

At S<b>201 , the CPU 1 acquires a data file storing electrocardiogram data to be automatically analyzed according to an operation from the operation unit 8 . The CPU 1 presents, for example, a file browser screen provided by the OS on the display unit 6, and allows the user to designate a data file to be acquired. Alternatively, the CPU 1 may search a predetermined location such as the memory card 4 and automatically acquire a data file (for example, a data file having a predetermined file name) that meets predetermined conditions.

The CPU 1 saves the acquired data file in the storage device 10 . It should be noted that instead of acquiring the entire data file all at once, a certain amount of electrocardiogram data stored in the data file may be acquired. In this embodiment, electrocardiogram data is assumed to be digital data A/D-converted under predetermined conditions. Also, the electrocardiogram data shall include the types and numbers of leads from which the X lead, Y lead, and Z lead can be derived. For example, but not limited to, 3 leads, eV1 lead, eV5 lead, and eVF lead, or standard 12 leads. Here, the electrocardiogram data for standard 12-leads is used. Also, although the electrocardiogram data measurement period is assumed to be 24 hours, it may exceed 24 hours. Moreover, if the measurement period is realistic for use in diagnosing arrhythmia, it may be less than 24 hours.

In S203, the CPU 1 applies preprocessing to the electrocardiogram data. The pre-processing may be a quality check process that detects bad signal segments unsuitable for analysis from the electrocardiogram data. In the quality check process, the CPU 1 evaluates, for example, the baseline level and superimposed noise, and determines sections where the superimposed level exceeds a threshold value and noise sections as bad signal sections and excludes them from analysis processing. When multiple channels (leads) are being measured by the Holter monitor, the CPU 1 applies preprocessing to the data of each channel.

The CPU 1 applies preprocessing to all data from the start to the end of measurement, and uses information that can identify the detected defective signal section (for example, start date and time and end date and time of the section) as data file identification information (for example, file name). They are stored in the storage device 10 in association with each other. The CPU 1 applies the subsequent processing to a section (called an analysis target section or effective signal section) of the electrocardiogram data excluding the defective signal section.

In S205, the CPU 1 generates a composite waveform by waveform synthesis processing. The waveform synthesizing process is a process of generating synthetic electrocardiogram data (composite waveform) for leads that are not measured, based on actually measured electrocardiogram data. The waveform synthesizing process makes it possible to obtain synthetic electrocardiogram data that would have been measured at a position on the body surface where no electrodes were attached during measurement.

By waveform synthesis processing, it is possible to obtain electrocardiogram data related to more types of leads than during measurement, so it is possible to support arrhythmia diagnosis without increasing the burden on the subject during measurement. For example, if standard 12-lead ECG data is being measured, a broader view of cardiac electrical potential activity may be obtained by generating synthetic ECG data for one or more of leads V3R-V6R and V7-V9. be possible. The V6R induction need not be synthesized because it is less clinically necessary than the V3R-V5R induction. Similarly, if 3-lead ECG data of leads eV1, eV5, and eVF have been measured, one or more standard 12-lead synthetic ECG data can be generated.

A composite waveform of leads at a position on the body surface (virtual electrode position) can be generated by known methods. For example, the CPU 1 generates electrocardiogram data of X-lead, Y-lead, and Z-lead from actually measured electrocardiogram data. Then, the CPU 1 obtains the inner product of the electrocardiogram data of the X lead, the Y lead, and the Z lead and the x, y, and z components of the lead vector at the virtual electrode position for each sample of the electrocardiogram data, thereby calculating the lead at the virtual electrode position. to generate synthetic electrocardiogram data. See, for example, Japanese Patent No. 4664068 and Japanese Patent No. 4955153 for specific examples of the waveform synthesizing process.

In this embodiment, long-term electrocardiograms are targeted. Therefore, if synthetic electrocardiogram data is generated over the entire measurement period, a considerable amount of processing time is required. Although it depends on the number of leads for generating synthetic electrocardiogram data and the processing capability of the electrocardiogram analysis apparatus 100, synthetic electrocardiogram data for 24 hours is generated for all leads V3R to V5R and leads V7 to V9 based on the 12-lead electrocardiogram data. For example, it may take several tens of minutes.

For example, when performing automatic analysis processing of electrocardiogram data for a large number of subjects, when automatic analysis processing needs to be performed at high speed, it is not necessary to wait several tens of minutes for waveform synthesis processing for each automatic analysis processing. unrealistic. Therefore, the electrocardiogram analysis apparatus 100 of the present embodiment can generate synthetic electrocardiogram data for a plurality of discrete periods in the electrocardiogram data measurement period. For example, after the CPU 1 generates synthetic electrocardiogram data for a certain time period of 1 minute to 1 second from the start of the measurement period (between valid signal units), the synthetic electrocardiogram data for a certain period of time is generated at regular intervals of 1 hour to 15 minutes. data can be generated.

In this way, by generating synthetic electrocardiogram data for a plurality of discrete periods in the electrocardiogram data measurement period, the time required for the waveform synthesizing process can be greatly reduced. Waveform synthesizing processing is performed considering the disadvantage that the time resolution of information obtained from synthetic electrocardiogram data is lower than the time resolution of information obtained from measured electrocardiogram data and the advantage of reducing processing time. The period and length of the period can be defined.

In S207, the CPU 1 calculates predetermined feature parameters for both the measured electrocardiogram data and the synthetic electrocardiogram data. Any characteristic parameter that can be observed to change over time can be calculated. Examples include, but are not limited to, beat-to-beat heart rate (HR), its variability (HRV), ST interval level relative to a reference level, and the like.

The CPU 1 divides the electrocardiogram data of each lead for which the feature parameter is to be calculated into each heartbeat and detects the QRS interval. For example, the CPU 1 detects candidates for the QRS segment based on the signal level, and detects a candidate determined to be highly reliable as the final QRS segment. Reliability can be determined, for example, based on one or more of signal quality, noise contamination, validity of RR intervals, whether other leads are also detected, and the like.

Then, the CPU 1 can calculate characteristic parameters based on the detected QRS interval. For example, HR and HRV can be calculated from the RR interval (RRI) of adjacent QRS intervals. Also, the ST interval is detected based on the detected QRS interval, and the signal level (minimum value, maximum value, or average value) of the ST interval when the reference level is 0 is calculated. The reference level can be, for example, a baseline level (eg, the level of the P-wave onset). The CPU 1 stores the calculated feature parameter in the storage device 10 for each lead, for example.

In S<b>209 , the CPU 1 outputs the trend display screen to the display section 6 . The CPU 1 may output a trend display screen according to a user instruction through a GUI provided by an electrocardiogram analysis application. The CPU 1 may output the trend display screen to an external display device or printer, or may output it as a data file.

FIG. 3A shows an example of a trend display screen 300. FIG. The trend display screen 300 has a configuration in which characteristic parameter values are plotted in a two-dimensional area having a time axis. Here, the two-dimensional area is a rectangular area having horizontal and vertical axes, and time is assigned to the horizontal axis and values to the vertical axis, but the elements assigned to the axes may be exchanged. The length of the period assigned to the time axis can be changed from pull-down menu 326 . In FIG. 3A, 27 hours are specified and the measurement period is 24 hours, so values are not plotted for the last 3 hours.

In FIG. 3A, trends of HR 310 and ST level 312 are displayed as feature parameters calculated from electrocardiogram data. The CPU 1 reads characteristic parameters according to the settings from the storage device 10 , generates data for the trend display screen 300 , and stores the data in the video memory area of the RAM 3 to display the trend display screen 300 on the display unit 6 .

The scroll bar 314 becomes effective when the trend of the entire measurement period cannot be displayed within the two-dimensional area. The CPU 1 horizontally scrolls the display contents according to the operation of the scroll bar 314 . Further, when detecting the operation of the top button 320 and the end button 322, the CPU 1 displays the trend in the range including the top and bottom of the measurement period.

When detecting the operation of the re-measurement button 318 , the CPU 1 redoes the calculation of the characteristic parameters for the previous measurement period, and reflects the results on the trend display screen 300 . The lead selection pull-down menu 324 is means for switching the lead to be displayed for the feature parameter calculated for each lead. If standard 12-lead and synthetic 6-lead (V3R-V5R and V7-V9) are present, 3-lead as one set, "I-III", "aVR-aVF", "V1-V3", "V4-V6" ”, “S-V3R-S-V5R”, and “S-V7-S-V9” can be switched. Here, "S-" in the lead name indicates synthetic lead.

Note that when the waveform synthesizing process is performed only for discrete periods, the time resolution of the feature parameters based on the synthetic electrocardiogram data is lower than the time resolution of the feature parameters based on the measured electrocardiogram data. Therefore, in trend display of feature parameters based on synthetic electrocardiogram data, adjacent plots of parameter values can be connected by straight lines in order to make it easier to grasp the trend of changes in parameter values over time.

In the example of FIG. 3A, the trend display screen 300 includes displays (Acc, Pos, Act) indicating the body position and activity state of the subject based on the information about the acceleration and posture measured together with the electrocardiogram. ing. 316 indicates a period determined to be sleeping.

Next, an operation corresponding to an operation within a two-dimensional area will be described. FIG. 3(b) shows an enlarged part of the ST level trend based on the synthetic electrocardiogram data. For example, by selecting a short time using the pull-down menu 326, it is possible to increase the display magnification in the direction of the time axis. Trends for other parameters such as HR are not shown for convenience.

When CPU 1 detects a position specifying operation within the two-dimensional area, CPU 1 displays a cursor 328 indicating the time corresponding to the specified position, and displays a pop-up menu in the vicinity of cursor 328 . The position specifying operation may be, for example, a mouse click while the mouse cursor is in the two-dimensional area, or a tap operation on the screen.

The pop-up menu contains selectable commands. Here, an instruction 330 for instructing additional generation of synthetic electrocardiogram data when synthetic electrocardiogram data is generated only for discrete periods, and an instruction 332 for instructing display of all lead waveforms including the synthetic waveform. Here is an example containing: Note that instruction 330 may not be included if synthetic ECG data is being generated for the entire time period over which the trend is being displayed.

When an operation to select command 330 is detected, CPU 1 generates synthetic electrocardiogram data for a predetermined period (for example, a fixed period around cursor 328) based on the time according to the operation position. Then, the CPU 1 calculates a feature parameter (here, ST level) based on the newly generated synthetic electrocardiogram data, and reflects it in the trend display.

On the other hand, when an operation to select command 332 is detected, CPU 1 displays a waveform display screen displaying a list of average waveforms of each lead of electrocardiogram data (including synthetic electrocardiogram data) included in a certain period around cursor 328. (Fig. 3(c)). In FIG. 3C showing an example of the waveform display screen 350, the four columns from the left end are standard 12-lead average waveforms, and the remaining two columns are synthetic 6-lead average waveforms. In addition, the ST level is also shown below the name of the lead.

Returning to the description of FIG. 2, in S211, the CPU 1 determines whether or not a user operation of the operation unit 8 has been detected while the trend display screen 300 is being displayed. If not determined, S211 is repeatedly executed.

In S213 and S217, the CPU 1 determines whether or not the detected operation is a specific operation within the two-dimensional area. Here, the specific operation is assumed to be a first operation (selection operation of command 330) for instructing addition of a measurement point and a second operation (selection for command 332) for instructing display of a list of waveforms. do. The CPU 1 executes S215 if it is determined that an operation instructing addition of a measurement point has been detected, and executes S219 if it is determined that an operation instructing display of a waveform list has been detected. When another operation is detected, the CPU 1 executes the operation corresponding to the operation such as the operation described with reference to FIG. 3, and then executes S211 again.

In S215, the CPU 1 sets a predetermined period based on the time corresponding to the operation position (for example, one beat or one second or longer including the time corresponding to the operation position), as described with reference to FIG. generate synthetic electrocardiogram data for Thereafter, the CPU 1 executes S207 and S209 to reflect the characteristic parameters based on the additionally generated synthetic electrocardiogram data on the trend display.

In S219, the CPU 1 displays a waveform list display screen as shown in FIG. 3(c) based on the electrocardiogram data for a predetermined period based on the time corresponding to the operating position. After that, the CPU 1 executes S211.

As described above, the electrocardiogram analysis apparatus of the present embodiment presents, for example, time changes in feature parameters based on electrocardiogram data, and provides time changes in feature parameters for leads that have not been measured based on synthetic electrocardiogram data. It has the function to Therefore, accurate arrhythmia diagnosis can be supported without increasing the burden on the subject when measuring the electrocardiogram for a long period of time.

In addition, the electrocardiogram analysis apparatus of this embodiment can generate synthetic electrocardiogram data for a plurality of discrete periods instead of generating synthetic electrocardiogram data over the entire long measurement period. Therefore, it is possible to prevent the processing time required for generating the synthetic electrocardiogram data from lowering the work efficiency of the diagnosis. Furthermore, even during a period in which synthetic electrocardiogram data is not generated, synthetic electrocardiogram data is generated in response to a user's instruction, and is reflected in the display of the temporal change of the feature parameters, which is convenient.

(Other embodiments)
The present invention can also be implemented as a program that causes a computer to function as the electrocardiogram analysis apparatus described in the above embodiments. Moreover, the present invention is not limited to the content of the above-described embodiments, and various modifications and variations are possible without departing from the spirit and scope of the invention. Accordingly, the claims are appended to make public the scope of the invention.

DESCRIPTION OF SYMBOLS 100... General-purpose computer (electrocardiogram analysis apparatus), 1... CPU, 4... Memory card, 10... Storage device, 200... External device

Claims (11)

Acquisition means for acquiring electrocardiogram data for a plurality of leads;
generating means for generating synthetic electrocardiogram data related to leads not included in the electrocardiogram data from the electrocardiogram data;
output means for outputting a trend display screen showing temporal changes in predetermined feature parameters of the lead included in the electrocardiogram data and the lead included in the composite electrocardiogram data;
An electrocardiogram analysis device, comprising: 2. The electrocardiogram analysis apparatus according to claim 1, wherein said generating means generates synthetic electrocardiogram data relating to one or more of leads V3R to V6R and leads V7 to V9, or one or more of standard 12 leads. 3. The electrocardiogram analysis apparatus according to claim 1, wherein the electrocardiogram data is electrocardiogram data measured by a Holter electrocardiograph. 3. The electrocardiogram analysis apparatus according to claim 1, wherein said plurality of leads are standard 12 leads, and said generating means generates synthetic electrocardiogram data for leads V3R to V5R and leads V7 to V9. 5. The electrocardiogram analysis apparatus according to any one of claims 1 to 4, wherein said generating means generates said synthetic electrocardiogram data for a plurality of discrete periods in the measurement period of said electrocardiogram data. The trend display screen has a configuration in which the predetermined characteristic parameter values are plotted in a two-dimensional area having a time axis,
In response to detecting a first manipulation of the two-dimensional region,
The generation means generates the synthetic electrocardiogram data for a predetermined period based on the time corresponding to the operation position,
the output means reflects the predetermined feature parameter based on the synthetic electrocardiogram data on the trend display screen;
6. The electrocardiogram analysis apparatus according to claim 5, characterized in that: The trend display screen has a configuration in which the predetermined characteristic parameter values are plotted in a two-dimensional area having a time axis,
In response to detection of a second operation on the two-dimensional area, the output means outputs a screen displaying a induced waveform for a predetermined period based on the time corresponding to the operation position.
The electrocardiogram analysis apparatus according to any one of claims 1 to 6, characterized in that: 8. The electrocardiogram analysis according to claim 7, wherein, when said synthetic electrocardiogram data has not been generated for said predetermined period, said generating means generates said synthetic electrocardiogram data for said predetermined period. Device. 9. The electrocardiogram analysis apparatus according to any one of claims 1 to 8, wherein said predetermined feature parameter is a parameter relating to ST interval level. an acquiring step of acquiring ECG data for a plurality of leads;
a generation step of generating synthetic electrocardiogram data related to leads not included in the electrocardiogram data from the electrocardiogram data;
an output step of outputting a trend display screen showing temporal changes in predetermined feature parameters of the leads included in the electrocardiogram data and the leads included in the composite electrocardiogram data;
A control method for an electrocardiogram analysis device, comprising: A program for causing a computer to function as each means of the electrocardiogram analysis apparatus according to any one of claims 1 to 9.

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