JP2022548698A - ベンゾオキサボロールポリマーおよび使用方法 - Google Patents

ベンゾオキサボロールポリマーおよび使用方法 Download PDF

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JP2022548698A
JP2022548698A JP2022517391A JP2022517391A JP2022548698A JP 2022548698 A JP2022548698 A JP 2022548698A JP 2022517391 A JP2022517391 A JP 2022517391A JP 2022517391 A JP2022517391 A JP 2022517391A JP 2022548698 A JP2022548698 A JP 2022548698A
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polymer
repeat units
integer
polymers
solution
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Japanese (ja)
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JPWO2021055752A5 (https=
JP2022548698A5 (https=
Inventor
トーマス ヘンリー ジョゼフィアック，
アシシュ ニムガオンカー，
スティーブン シー． ポロモスカニク，
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グライセンド， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F230/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal
    • C08F230/04—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal
    • C08F230/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing boron
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/42—Introducing metal atoms or metal-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2022517391A 2019-09-20 2020-09-18 ベンゾオキサボロールポリマーおよび使用方法 Withdrawn JP2022548698A (ja)

Priority Applications (1)

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JP2024202452A JP2025019142A (ja) 2019-09-20 2024-11-20 ベンゾオキサボロールポリマーおよび使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962903332P 2019-09-20 2019-09-20
US62/903,332 2019-09-20
PCT/US2020/051499 WO2021055752A1 (en) 2019-09-20 2020-09-18 Benzoxaborole polymers and methods of use

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JP2024202452A Division JP2025019142A (ja) 2019-09-20 2024-11-20 ベンゾオキサボロールポリマーおよび使用方法

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JP2022548698A true JP2022548698A (ja) 2022-11-21
JPWO2021055752A5 JPWO2021055752A5 (https=) 2023-09-28
JP2022548698A5 JP2022548698A5 (https=) 2023-09-28

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JP2024202452A Pending JP2025019142A (ja) 2019-09-20 2024-11-20 ベンゾオキサボロールポリマーおよび使用方法

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US (1) US20220396651A1 (https=)
EP (1) EP4041740A4 (https=)
JP (2) JP2022548698A (https=)
WO (1) WO2021055752A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021055759A1 (en) 2019-09-20 2021-03-25 Glyscend, Inc. Substituted phenyl boronic acid containing polymers and methods of use
WO2025122491A1 (en) * 2023-12-04 2025-06-12 Aviko Radiopharmaceuticals, Llc Fused bicyclic aryl compounds for boron neutron capture therapy
WO2025144975A1 (en) * 2023-12-28 2025-07-03 Aviko Radiopharmaceuticals, Llc Fused bicyclic aryl compounds for boron neutron capture therapy

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0782320A (ja) * 1993-09-14 1995-03-28 Showa Denko Kk 高分子化合物およびその製造方法
WO2017061435A1 (ja) * 2015-10-06 2017-04-13 国立研究開発法人物質・材料研究機構 ビニルアルコール樹脂機能化方法並びにビニルアルコール樹脂機能化剤
US20180228863A1 (en) * 2015-08-06 2018-08-16 The Johns Hopkins University Composition and method for treatment of metabolic disorders
CN108478779A (zh) * 2018-04-12 2018-09-04 南京邮电大学 一种肿瘤靶向纳米药物及其制备方法和用途
JP2019152296A (ja) * 2018-03-06 2019-09-12 株式会社竹村製作所 樹脂管用継手

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003291567A1 (en) * 2002-11-19 2004-06-15 Genzyme Corporation Polymeric boronic acid derivatives as lipase inhibitors
EP2226075A1 (en) * 2007-11-22 2010-09-08 The University of Tokyo Material for preventing tissue adhesion and material for preventing joint contracture

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0782320A (ja) * 1993-09-14 1995-03-28 Showa Denko Kk 高分子化合物およびその製造方法
US20180228863A1 (en) * 2015-08-06 2018-08-16 The Johns Hopkins University Composition and method for treatment of metabolic disorders
WO2017061435A1 (ja) * 2015-10-06 2017-04-13 国立研究開発法人物質・材料研究機構 ビニルアルコール樹脂機能化方法並びにビニルアルコール樹脂機能化剤
JP2019152296A (ja) * 2018-03-06 2019-09-12 株式会社竹村製作所 樹脂管用継手
CN108478779A (zh) * 2018-04-12 2018-09-04 南京邮电大学 一种肿瘤靶向纳米药物及其制备方法和用途

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HAN LU ETAL.: "Temperature- and pH-Responsive Benzoboroxole-Based Polymers for Flocculation and Enhanced Dewatering", ACS APPLIED MATERIALS & INTERFACES, vol. 7, no. 49, JPN6024033038, 3 December 2015 (2015-12-03), pages 27176 - 27187, ISSN: 0005534613 *
JULIE I. JAYET AL.: "Multivalent Benzoboroxole Functionalized Polymers as gp120 Glycan Targeted Microbicide Entry Inhibit", MOLECULAR PHARMACEUTICS, vol. 7, no. 1, JPN6024033036, 16 December 2009 (2009-12-16), pages 116 - 129, XP055114115, ISSN: 0005534611, DOI: 10.1021/mp900159n *
KOTSUCHIBASHI YOHEI ET AL.: "Temperature, pH, and Glucose Responsive Gels via Simple Mixing of Boroxole- and Glyco-Based Polymers", ACS MACRO LETTERS, vol. 2, no. 3, JPN6024033035, 3 July 2013 (2013-07-03), pages 260 - 264, XP055376139, ISSN: 0005534610, DOI: 10.1021/mz400076p *
YANGJUN CHEN ET AL.: "Injectable Self-Healing Zwitterionic Hydrogels Based on Dynamic Benzoxaborole-Sugar Interactions wit", BIOMACROMOLECULES, vol. 19, no. 2, JPN6024033037, 27 January 2018 (2018-01-27), pages 596 - 605, XP093082766, ISSN: 0005534612, DOI: 10.1021/acs.biomac.7b01679 *

Also Published As

Publication number Publication date
EP4041740A4 (en) 2023-10-25
JP2025019142A (ja) 2025-02-06
US20220396651A1 (en) 2022-12-15
EP4041740A1 (en) 2022-08-17
WO2021055752A1 (en) 2021-03-25

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