JP2022548001A - 皮内投与用混合ワクチン - Google Patents

皮内投与用混合ワクチン Download PDF

Info

Publication number
JP2022548001A
JP2022548001A JP2022515948A JP2022515948A JP2022548001A JP 2022548001 A JP2022548001 A JP 2022548001A JP 2022515948 A JP2022515948 A JP 2022515948A JP 2022515948 A JP2022515948 A JP 2022515948A JP 2022548001 A JP2022548001 A JP 2022548001A
Authority
JP
Japan
Prior art keywords
combination vaccine
pcv2
mhyo
vaccine
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022515948A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022548001A5 (https=
Inventor
ヤンセン，テオドルス
スノ，メラニー
ウィトフリート，マールテン・ヘンドリック
ピエスト，マルティン
Original Assignee
インターベット インターナショナル ベー． フェー．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by インターベット インターナショナル ベー． フェー． filed Critical インターベット インターナショナル ベー． フェー．
Publication of JP2022548001A publication Critical patent/JP2022548001A/ja
Publication of JP2022548001A5 publication Critical patent/JP2022548001A5/ja
Priority to JP2025051601A priority Critical patent/JP2025106086A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
JP2022515948A 2019-09-12 2020-09-11 皮内投与用混合ワクチン Pending JP2022548001A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025051601A JP2025106086A (ja) 2019-09-12 2025-03-26 皮内投与用混合ワクチン

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19196890.8 2019-09-12
EP19196890 2019-09-12
PCT/EP2020/075454 WO2021048338A1 (en) 2019-09-12 2020-09-11 Combination vaccine for intradermal administration

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025051601A Division JP2025106086A (ja) 2019-09-12 2025-03-26 皮内投与用混合ワクチン

Publications (2)

Publication Number Publication Date
JP2022548001A true JP2022548001A (ja) 2022-11-16
JP2022548001A5 JP2022548001A5 (https=) 2023-05-22

Family

ID=68136125

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022515948A Pending JP2022548001A (ja) 2019-09-12 2020-09-11 皮内投与用混合ワクチン
JP2025051601A Pending JP2025106086A (ja) 2019-09-12 2025-03-26 皮内投与用混合ワクチン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025051601A Pending JP2025106086A (ja) 2019-09-12 2025-03-26 皮内投与用混合ワクチン

Country Status (9)

Country Link
US (1) US20220323567A1 (https=)
EP (1) EP4028050A1 (https=)
JP (2) JP2022548001A (https=)
KR (1) KR20220062345A (https=)
CN (1) CN114364398B (https=)
BR (1) BR112022004256A2 (https=)
CA (1) CA3149027A1 (https=)
MX (1) MX2022003090A (https=)
WO (1) WO2021048338A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023118553A1 (en) 2021-12-24 2023-06-29 Intervet International B.V. Stable emulsions of antigens
CN121219005A (zh) 2023-05-12 2025-12-26 英特维特国际股份有限公司 一种针对猪红斑丹毒丝菌、猪细小病毒及钩端螺旋体菌的联合疫苗
WO2024235714A1 (en) 2023-05-12 2024-11-21 Intervet International B.V. A vaccine against leptospira bacterium
WO2024235713A1 (en) 2023-05-12 2024-11-21 Intervet International B.V. A vaccine against erysipelothrix rhusiopathiae and porcine parvo virus

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018115435A1 (en) * 2016-12-23 2018-06-28 Intervet International B.V. Combination vaccine for swine
JP2019509300A (ja) * 2016-03-23 2019-04-04 インターベット インターナショナル ベー． フェー． Ｐｃｖ２ウイルス及びマイコプラズマ・ハイオニューモニエ感染症に対する混合ワクチン
WO2019121916A1 (en) * 2017-12-22 2019-06-27 Hipra Scientific, S.L.U. Intradermal combination vaccine against mycoplasma and porcine circovirus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101347503B1 (ko) 2005-09-09 2014-01-02 인터벳 인터내셔널 비.브이. Ｐｃｖ-2 백신
MX338626B (es) 2005-12-29 2016-04-26 Boehringer Ingelheim Vetmed Uso de una composicion inmunogenica de pcv2 para producir los sintomas clinicos en cerdos.
JP5200223B2 (ja) 2006-12-15 2013-06-05 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド Ｐｃｖ２抗原によるブタの処置
JP6648138B2 (ja) * 2014-12-11 2020-02-14 インターベット インターナショナル ベー． フェー． 即時使用型ＰＣＶ２／Ｍ．ハイオ（Ｍ．ｈｙｏ）混合ワクチンのための工程

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509300A (ja) * 2016-03-23 2019-04-04 インターベット インターナショナル ベー． フェー． Ｐｃｖ２ウイルス及びマイコプラズマ・ハイオニューモニエ感染症に対する混合ワクチン
WO2018115435A1 (en) * 2016-12-23 2018-06-28 Intervet International B.V. Combination vaccine for swine
WO2019121916A1 (en) * 2017-12-22 2019-06-27 Hipra Scientific, S.L.U. Intradermal combination vaccine against mycoplasma and porcine circovirus

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EUR. J. PHARMACEUT, SCI., vol. 63, JPN6024026126, 2014, pages 154 - 166, ISSN: 0005474842 *
JOHAN LINDEN: "Surface modified silica nanoparticles as emulsifier", MASTER OF SCIENCE THESIS, JPN6024026124, 2012, ISSN: 0005474844 *
PHARM. RES., vol. 34, JPN6024026125, 2017, pages 1693 - 1706, ISSN: 0005474843 *

Also Published As

Publication number Publication date
EP4028050A1 (en) 2022-07-20
CN114364398B (zh) 2025-08-22
MX2022003090A (es) 2022-04-11
KR20220062345A (ko) 2022-05-16
BR112022004256A2 (pt) 2022-06-21
CA3149027A1 (en) 2021-03-18
JP2025106086A (ja) 2025-07-11
CN114364398A (zh) 2022-04-15
US20220323567A1 (en) 2022-10-13
WO2021048338A1 (en) 2021-03-18

Similar Documents

Publication Publication Date Title
RU2761453C2 (ru) Комбинированная вакцина для свиней
AU2006236711B2 (en) Novel vaccine formulations
TWI353850B (en) Microfluidized oil-in-water emulsions and vaccine
JP6648138B2 (ja) 即時使用型ＰＣＶ２／Ｍ．ハイオ（Ｍ．ｈｙｏ）混合ワクチンのための工程
CN114364398B (zh) 用于皮内施用的联合疫苗
US20250057934A1 (en) Stable emulsions of antigens
RU2835620C1 (ru) Комбинированная вакцина для внутрикожного введения
US20150086587A1 (en) Vaccine adjuvant
BR122025019595A2 (pt) Vacina de combinação para suínos, seus métodos de preparação, kit de partes, emulsão óleo-em-água e uso
BR112019012504B1 (pt) Vacina de combinação para suínos, seus métodos de preparação, kit de partes e uso

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230512

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20230512

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240709

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20241008

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20241203