|
US20050186593A1
(en)
|
1991-05-10 |
2005-08-25 |
The Salk Institute For Biological Studies |
Cloning and recombinant production of CRF receptor(s)
|
|
US6656475B1
(en)
|
1997-08-01 |
2003-12-02 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
|
|
JP4544742B2
(ja)
|
1998-05-06 |
2010-09-15 |
メタモーフイクス・インコーポレーテツド |
Gdf−8の阻害による糖尿病の処置法
|
|
JP2008507288A
(ja)
|
2004-07-23 |
2008-03-13 |
アクセルロン ファーマ インコーポレーテッド |
ActRII受容体ポリペプチド、方法、および組成物
|
|
PE20120532A1
(es)
*
|
2009-04-27 |
2012-05-18 |
Novartis Ag |
ANTICUERPOS ANTI-ActRIIB
|
|
AU2010315245B2
(en)
*
|
2009-11-03 |
2016-11-03 |
Acceleron Pharma Inc. |
Methods for treating fatty liver disease
|
|
KR101461706B1
(ko)
*
|
2011-04-04 |
2014-11-18 |
한국생명공학연구원 |
Dlk1 세포 외 수용성 도메인을 포함하는 액티빈 수용체 타입 2b 억제제
|
|
CN104513213A
(zh)
|
2013-09-28 |
2015-04-15 |
山东亨利医药科技有限责任公司 |
Fxr激动剂
|
|
EP3116878A4
(en)
|
2014-03-13 |
2018-02-14 |
Salk Institute for Biological Studies |
Fxr agonists and methods for making and using
|
|
MA41052A
(fr)
|
2014-10-09 |
2017-08-15 |
Celgene Corp |
Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii
|
|
CN111662297A
(zh)
|
2014-11-21 |
2020-09-15 |
阿卡纳治疗学有限公司 |
用于治疗疾病的稠合双环化合物
|
|
EP3034499A1
(en)
|
2014-12-17 |
2016-06-22 |
Gilead Sciences, Inc. |
Novel FXR (NR1H4) modulating compounds
|
|
EP3034501A1
(en)
|
2014-12-17 |
2016-06-22 |
Gilead Sciences, Inc. |
Hydroxy containing FXR (NR1H4) modulating compounds
|
|
WO2016103037A1
(en)
|
2014-12-22 |
2016-06-30 |
Akarna Therapeutics, Ltd. |
Fused bicyclic compounds for the treatment of disease
|
|
TWI698430B
(zh)
|
2015-02-13 |
2020-07-11 |
南北兄弟藥業投資有限公司 |
三環化合物及其在藥物中的應用
|
|
WO2017078928A1
(en)
|
2015-11-06 |
2017-05-11 |
Salk Institute For Biological Studies |
Fxr agonists and methods for making and using
|
|
CN106946867B
(zh)
|
2016-01-06 |
2019-11-12 |
广州市恒诺康医药科技有限公司 |
Fxr受体调节剂及其制备方法和用途
|
|
WO2017128896A1
(zh)
|
2016-01-26 |
2017-08-03 |
江苏豪森药业集团有限公司 |
Fxr激动剂及其制备方法和应用
|
|
WO2017143134A1
(en)
|
2016-02-19 |
2017-08-24 |
Alios Biopharma, Inc. |
Fxr modulators and methods of their use
|
|
US20170240639A1
(en)
|
2016-02-22 |
2017-08-24 |
Acceleron Pharma Inc. |
Actrii antagonists for use in increasing immune activity
|
|
WO2017189651A1
(en)
|
2016-04-26 |
2017-11-02 |
Enanta Pharmaceuticals, Inc. |
Isoxazole derivatives as fxr agonists and methods of use thereof
|
|
US10080741B2
(en)
|
2016-04-26 |
2018-09-25 |
Enanta Pharmaceuticals, Inc. |
Isoxazole derivatives as FXR agonists and methods of use thereof
|
|
WO2017189663A1
(en)
|
2016-04-26 |
2017-11-02 |
Enanta Pharmaceuticals, Inc. |
Isoxazole derivatives as fxr agonists and methods of use thereof
|
|
WO2017201152A1
(en)
|
2016-05-18 |
2017-11-23 |
Enanta Pharmaceuticals, Inc. |
Isoxazole derivatives as fxr agonists and methods of use thereof
|
|
US10144729B2
(en)
|
2016-05-18 |
2018-12-04 |
Enanta Pharmaceuticals, Inc. |
Isoxazole analogs as FXR agonists and methods of use thereof
|
|
WO2017201155A1
(en)
|
2016-05-18 |
2017-11-23 |
Enanta Pharmaceuticals, Inc. |
lSOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF
|
|
US10183872B2
(en)
|
2016-06-13 |
2019-01-22 |
Qi Wang |
Counter circulating liquid processing system by repeatedly re-using thermal energy
|
|
NZ748641A
(en)
|
2016-06-13 |
2020-04-24 |
Gilead Sciences Inc |
Fxr (nr1h4) modulating compounds
|
|
TW201808283A
(zh)
|
2016-08-05 |
2018-03-16 |
廣東東陽光藥業有限公司 |
含氮三環化合物及其在藥物中的應用
|
|
US11091482B2
(en)
|
2016-08-23 |
2021-08-17 |
Ardelyx, Inc. |
Isoxazolyl-carbonyloxy azabicyclo[3.2.1]octanyl compounds as FXR activators
|
|
CN108430998B
(zh)
|
2016-09-28 |
2021-07-09 |
四川科伦博泰生物医药股份有限公司 |
氮杂双环衍生物及其制备方法和用途
|
|
MX2019003790A
(es)
|
2016-10-04 |
2019-09-26 |
Enanta Pharm Inc |
Analogos de isoxazol como agonistas de fxr y metodos de uso de los mismos.
|
|
CN107973790A
(zh)
|
2016-10-22 |
2018-05-01 |
合帕吉恩治疗公司 |
杂环fxr调节剂
|
|
WO2018081285A1
(en)
|
2016-10-26 |
2018-05-03 |
Enanta Pharmaceuticals, Inc. |
Urea-containing isoxazole derivatives as fxr agonists and methods of use thereof
|
|
CN108017636A
(zh)
|
2016-11-04 |
2018-05-11 |
合帕吉恩治疗公司 |
作为fxr调节剂的含氮杂环化合物
|
|
JOP20190152A1
(ar)
|
2016-12-21 |
2019-06-20 |
Novartis Ag |
مضادات الميوستاتين، الآكتيفين أو مستقبلات الآكتيفين للاستخدام في علاج السمنة والحالات ذات الصلة
|
|
CN109071468B
(zh)
|
2017-01-20 |
2022-09-02 |
四川科伦博泰生物医药股份有限公司 |
一种杂环化合物及其制备方法和用途
|
|
WO2018190643A1
(en)
|
2017-04-12 |
2018-10-18 |
Il Dong Pharmaceutical Co., Ltd. |
An isoxazole derivatives as nuclear receptor agonists and used thereof
|
|
US11339147B2
(en)
|
2017-05-26 |
2022-05-24 |
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. |
Lactam compound as FXR receptor agonist
|
|
KR102400183B1
(ko)
|
2017-07-06 |
2022-05-18 |
수안주 바이오파마슈티컬 컴퍼니 리미티드 |
Fxr 작용제
|
|
CN109053751A
(zh)
|
2018-08-30 |
2018-12-21 |
成都海博锐药业有限公司 |
具有螺环结构的fxr调节剂
|