JP2022545078A5 - - Google Patents

Info

Publication number
JP2022545078A5
JP2022545078A5 JP2022510802A JP2022510802A JP2022545078A5 JP 2022545078 A5 JP2022545078 A5 JP 2022545078A5 JP 2022510802 A JP2022510802 A JP 2022510802A JP 2022510802 A JP2022510802 A JP 2022510802A JP 2022545078 A5 JP2022545078 A5 JP 2022545078A5
Authority
JP
Japan
Prior art keywords
cells
positive
population
induction medium
precursor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022510802A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022545078A (ja
Filing date
Publication date
Priority claimed from GBGB1911953.6A external-priority patent/GB201911953D0/en
Application filed filed Critical
Publication of JP2022545078A publication Critical patent/JP2022545078A/ja
Publication of JP2022545078A5 publication Critical patent/JP2022545078A5/ja
Pending legal-status Critical Current

Links

JP2022510802A 2019-08-20 2020-08-20 RAGが不活性化されたiPSCからのT細胞生産 Pending JP2022545078A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1911953.6 2019-08-20
GBGB1911953.6A GB201911953D0 (en) 2019-08-20 2019-08-20 T cell production fram RAG inacivated iPSCs
PCT/EP2020/073400 WO2021032852A1 (en) 2019-08-20 2020-08-20 T cell production from rag inactivated ipscs

Publications (2)

Publication Number Publication Date
JP2022545078A JP2022545078A (ja) 2022-10-25
JP2022545078A5 true JP2022545078A5 (enExample) 2023-08-18

Family

ID=68099394

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022510802A Pending JP2022545078A (ja) 2019-08-20 2020-08-20 RAGが不活性化されたiPSCからのT細胞生産

Country Status (12)

Country Link
US (1) US20220275332A1 (enExample)
EP (1) EP4017968A1 (enExample)
JP (1) JP2022545078A (enExample)
KR (1) KR20220044844A (enExample)
CN (1) CN114269904A (enExample)
AU (1) AU2020334258A1 (enExample)
BR (1) BR112022003093A2 (enExample)
CA (1) CA3150429A1 (enExample)
GB (1) GB201911953D0 (enExample)
IL (1) IL290604A (enExample)
MX (1) MX2022001959A (enExample)
WO (1) WO2021032852A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022001961A (es) * 2019-08-20 2022-03-11 Adaptimmune Ltd Medio de cultivo para induccion de hematopoyesis.
GB202006903D0 (en) * 2020-05-11 2020-06-24 Adaptimmune Ltd Modified iPSCs
WO2022059780A1 (ja) * 2020-09-18 2022-03-24 サイアス株式会社 iPS細胞を介する再生T細胞の製造方法
GB202111169D0 (en) * 2021-08-03 2021-09-15 Adaptimmune Ltd Methods of T cell production
CN114517176B (zh) * 2022-01-27 2022-12-02 广东普罗凯融生物医药科技有限公司 一种将ips细胞诱导成nk细胞的试剂盒及其应用方法
GB202205572D0 (en) 2022-04-14 2022-06-01 Adaptimmune Ltd Engineered T cells
GB202208545D0 (en) 2022-06-10 2022-07-27 Adaptimmune Ltd Production of immune cells
GB202318950D0 (en) 2023-12-12 2024-01-24 Adaptimmune Ltd Production of immune cells
CN118421559B (zh) * 2024-07-04 2024-09-27 成都赛济元生物医药有限公司 定向分化淋巴造血前体细胞的小分子组合、试剂盒及方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012061075A2 (en) * 2010-10-25 2012-05-10 The Regents Of The University Of California Hiv resistant and functional hematopoietic stem/progenitor cells and macrophages from induced pluripotent stem cells
SG11201507275TA (en) * 2013-03-13 2015-10-29 Wisconsin Alumni Res Found Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions
SG10201900323SA (en) * 2014-07-18 2019-02-27 Univ Kyoto Method for inducing t cells for cell-based immunotherapy from pluripotent stem cells
AU2016344135A1 (en) * 2015-10-27 2018-06-14 Board Of Regents, The University Of Texas System Engineering of humanized car T-cells and platelets by genetic complementation
WO2017078807A1 (en) * 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
JP2019080491A (ja) * 2016-03-16 2019-05-30 国立大学法人京都大学 免疫細胞療法用ny−eso1抗原特異的t細胞の誘導方法
JP2021513839A (ja) * 2018-02-16 2021-06-03 カイト ファーマ インコーポレイテッドKite Pharma, Inc 改変された多能性幹細胞並びに製造方法及び使用方法
MX2022001961A (es) * 2019-08-20 2022-03-11 Adaptimmune Ltd Medio de cultivo para induccion de hematopoyesis.

Similar Documents

Publication Publication Date Title
JP2022545415A5 (enExample)
JP2022545782A5 (enExample)
JP7613712B2 (ja) 抗原特異的t細胞の製造方法
US12024717B2 (en) Method for reconstructing immune function using pluripotent stem cells
KR102598351B1 (ko) 만능 줄기 세포를 hla 동형 접합 면역 세포로 직접 분화시키기 위한 방법
JP2021191294A (ja) 多能性幹細胞を用いた免疫機能再建法
KR20180063333A (ko) 면역 세포로의 만능 줄기 세포의 지정된 분화 방법
JP2019526266A (ja) 人工多能性幹細胞由来の免疫細胞
WO2009034172A1 (en) Enhancing the t-cells stimulatory capacity of human antigen presenting cells and their use in vaccination
US12421496B2 (en) Method for producing natural killer cell and use thereof
SG10202106515SA (en) Methods and kits for generating mimetic innate immune cells from pluripotent stem cells
KR20150126943A (ko) 규정된 조건하에서 인간 만능성 줄기 세포의 조혈내피세포 분화를 위한 방법 및 재료
CN102329769A (zh) 一种获得造血干细胞的方法
JP2024507472A5 (enExample)
Martin et al. Differences in lymphocyte developmental potential between human embryonic stem cell and umbilical cord blood–derived hematopoietic progenitor cells
JP2022545416A5 (enExample)
US20150087065A1 (en) Method for generation of conditionally immortalized hematopoietic progenitor cell lines with multiple lineage potential
JP2023502318A (ja) 細胞を再プログラム化して形質細胞様樹状細胞またはi型インターフェロン産生細胞に変換する組成物、その方法および用途
CN115087732B (zh) 来自人T细胞来源的iPS细胞的细胞毒性T细胞
Kawai et al. Feeder-free generation of CD4 single-positive helper T cells from human iPSCs via stage-specific modulation of Notch and TCR Signaling
TW202235094A (zh) 經回春的t細胞之製造方法、包含彼之組成物、及彼之使用方法
JP2018093823A (ja) 未分化幹細胞除去剤及び未分化幹細胞除去方法
RU2022107097A (ru) Получение т-клеток из ipsc с инактивированным rag
RU2022107099A (ru) Культуральная среда для гемопоэтической индукции
JP2023554441A (ja) 細胞リプログラミングのための組成物、構築物及びベクター