JP2022543244A5 - - Google Patents

Info

Publication number
JP2022543244A5
JP2022543244A5 JP2022506659A JP2022506659A JP2022543244A5 JP 2022543244 A5 JP2022543244 A5 JP 2022543244A5 JP 2022506659 A JP2022506659 A JP 2022506659A JP 2022506659 A JP2022506659 A JP 2022506659A JP 2022543244 A5 JP2022543244 A5 JP 2022543244A5
Authority
JP
Japan
Prior art keywords
compound
approximately
optionally substituted
aminosterol
symptom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022506659A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022543244A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/044392 external-priority patent/WO2021025974A1/en
Publication of JP2022543244A publication Critical patent/JP2022543244A/ja
Publication of JP2022543244A5 publication Critical patent/JP2022543244A5/ja
Pending legal-status Critical Current

Links

JP2022506659A 2019-08-02 2020-07-31 ヒトスクアラミン誘導体、それを含む関連組成物、およびそれを用いた方法 Pending JP2022543244A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962882318P 2019-08-02 2019-08-02
US62/882,318 2019-08-02
US202063036828P 2020-06-09 2020-06-09
US63/036,828 2020-06-09
PCT/US2020/044392 WO2021025974A1 (en) 2019-08-02 2020-07-31 Human squalamine derivatives, related compositions comprising the same, and methods of using the same

Publications (2)

Publication Number Publication Date
JP2022543244A JP2022543244A (ja) 2022-10-11
JP2022543244A5 true JP2022543244A5 (https=) 2023-08-07

Family

ID=74503104

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022506659A Pending JP2022543244A (ja) 2019-08-02 2020-07-31 ヒトスクアラミン誘導体、それを含む関連組成物、およびそれを用いた方法

Country Status (5)

Country Link
US (1) US20220372066A1 (https=)
EP (1) EP4007765A4 (https=)
JP (1) JP2022543244A (https=)
CA (1) CA3149480A1 (https=)
WO (1) WO2021025974A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12503485B2 (en) 2019-08-02 2025-12-23 Enterin, Inc. Human aminosterol ENT-03 compounds, related compositions comprising the same, and methods of using the same
WO2021216399A1 (en) * 2020-04-20 2021-10-28 Enterin, Inc. Pulmonary aminosterol compositions and methods of using the same to treat microbial infections
WO2022226116A1 (en) * 2021-04-21 2022-10-27 Oxeia Biopharmaceuticals, Inc. Ghrelin treatment of brain dysfunction due to viral infection
WO2023038858A1 (en) * 2021-09-10 2023-03-16 Edifice Health, Inc. Methods and compositions for diagnosing and treating covid-19
CN113975278B (zh) * 2021-10-29 2023-04-07 中国科学院昆明动物研究所 溴隐亭在制备治疗非洲猪瘟的产品中的应用
WO2023146838A1 (en) * 2022-01-25 2023-08-03 Enterin, Inc. Methods for treating or preventing neurodegenerative disease using a combination of aminosterols and an insulin compound
WO2023146842A1 (en) * 2022-01-25 2023-08-03 Enterin, Inc. C25 r and s isomers of aminosterols and methods of making and using the same
CN118085053A (zh) * 2022-11-25 2024-05-28 深圳先进技术研究院 以Inx5基因或以Inx5蛋白作为作用靶点的物质的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994020520A1 (en) * 1993-03-10 1994-09-15 Magainin Pharmaceuticals Inc. Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
US5856535A (en) * 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
US5792635A (en) * 1995-06-07 1998-08-11 Magainin Pharmaceuticals, Inc. Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
AU723663C (en) * 1995-06-07 2001-11-01 Magainin Pharmaceuticals, Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE), pharmaceutical methods and compositions employing such inhibitors, and processes for evaluating the NHE-inhibitory efficacy of compounds
WO2009032321A2 (en) * 2007-09-06 2009-03-12 Genaera Corporation A method for treating diabetes
MX367255B (es) * 2012-04-20 2019-08-12 Ohr Pharmaceutical Inc Aminoesteroides para tratamiento de una enfermedad asociada con proteina fosfatasa 1b (ptp1b).
EP2934543B1 (en) * 2012-12-20 2018-10-31 Mount Desert Island Biological Laboratory Stimulation and enhancement of regeneration of tissues
GB201303589D0 (en) * 2013-02-27 2013-04-10 Univ Swansea Compound and method for the treatment of neurodegenerative conditions
GB201316050D0 (en) * 2013-09-10 2013-10-23 Univ Swansea Deuterated compounds
EP3083656A1 (en) * 2013-12-20 2016-10-26 Prevacus Inc. Synthesis of ent-progesterone and intermediates thereof
FR3055801B1 (fr) * 2016-09-15 2020-10-30 Virbac Derives esters de squalamine pour le traitement des infections
FR3055802B1 (fr) * 2016-09-15 2018-08-24 Virbac Derives amides de squalamine pour le traitement des infections
US20230125585A1 (en) * 2019-08-02 2023-04-27 Enterin, Inc. Dosing protocols and regimens for aminosterol treatment
US12503485B2 (en) * 2019-08-02 2025-12-23 Enterin, Inc. Human aminosterol ENT-03 compounds, related compositions comprising the same, and methods of using the same

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