JP2022537448A - 病態特異的抗原を同定するためのイムノームワイド関連研究 - Google Patents

病態特異的抗原を同定するためのイムノームワイド関連研究 Download PDF

Info

Publication number
JP2022537448A
JP2022537448A JP2021576239A JP2021576239A JP2022537448A JP 2022537448 A JP2022537448 A JP 2022537448A JP 2021576239 A JP2021576239 A JP 2021576239A JP 2021576239 A JP2021576239 A JP 2021576239A JP 2022537448 A JP2022537448 A JP 2022537448A
Authority
JP
Japan
Prior art keywords
antigen
cohort
mer
disease
enrichment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021576239A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022537448A5 (https=
Inventor
ジョン ション
ウィンストン エイ. ハイネス
パトリック ショーン ドーアティー
Original Assignee
セリミューン インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by セリミューン インコーポレイテッド filed Critical セリミューン インコーポレイテッド
Publication of JP2022537448A publication Critical patent/JP2022537448A/ja
Publication of JP2022537448A5 publication Critical patent/JP2022537448A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G16B35/20Screening of libraries
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30Detection of binding sites or motifs
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/50Mutagenesis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00ICT specially adapted for the handling or processing of medical references
    • G16H70/40ICT specially adapted for the handling or processing of medical references relating to drugs, e.g. their side effects or intended usage
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Data Mining & Analysis (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Library & Information Science (AREA)
  • Medicinal Chemistry (AREA)
  • Software Systems (AREA)
  • Primary Health Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Databases & Information Systems (AREA)
  • Evolutionary Computation (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021576239A 2019-06-21 2020-06-20 病態特異的抗原を同定するためのイムノームワイド関連研究 Pending JP2022537448A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962864909P 2019-06-21 2019-06-21
US62/864,909 2019-06-21
PCT/US2020/038856 WO2020257740A2 (en) 2019-06-21 2020-06-20 Immunome wide association studies to identify condition-specific antigens

Publications (2)

Publication Number Publication Date
JP2022537448A true JP2022537448A (ja) 2022-08-25
JP2022537448A5 JP2022537448A5 (https=) 2023-06-27

Family

ID=74037099

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021576239A Pending JP2022537448A (ja) 2019-06-21 2020-06-20 病態特異的抗原を同定するためのイムノームワイド関連研究

Country Status (4)

Country Link
US (1) US20230024898A1 (https=)
EP (1) EP3987053A4 (https=)
JP (1) JP2022537448A (https=)
WO (1) WO2020257740A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023060267A1 (en) * 2021-10-07 2023-04-13 Serimmune Inc. Global protein-based immunome wide association studies

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180267056A1 (en) * 2015-11-11 2018-09-20 Serimmune Inc. Methods and compositions for assessing antibody specificities
JP2020511633A (ja) * 2017-02-22 2020-04-16 ヘルステル・インコーポレイテッドHealthtell Inc. 感染のスクリーニング方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017357818A1 (en) * 2016-11-11 2019-05-30 HealthTell, Inc. Methods for identifying candidate biomarkers

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180267056A1 (en) * 2015-11-11 2018-09-20 Serimmune Inc. Methods and compositions for assessing antibody specificities
JP2020511633A (ja) * 2017-02-22 2020-04-16 ヘルステル・インコーポレイテッドHealthtell Inc. 感染のスクリーニング方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PAULL, MICHAEL LOUIS: "Development of bioinformatic tools to identify and characterize linear protein epitopes", UC SANTA BARBARA ELECTRONIC THESES AND DISSERTATIONS[ONLINE], JPN6024031458, 2018, US, pages 26 - 27, ISSN: 0005515888 *

Also Published As

Publication number Publication date
WO2020257740A2 (en) 2020-12-24
EP3987053A4 (en) 2023-12-13
US20230024898A1 (en) 2023-01-26
EP3987053A2 (en) 2022-04-27
WO2020257740A3 (en) 2021-02-18

Similar Documents

Publication Publication Date Title
Xu et al. COVID‐19 diagnostic testing: technology perspective
CN107002289B (zh) 用于定量评价dna-蛋白质复合物密度的组合物和方法
Karthikeyan et al. A contra capture protein array platform for studying post-translationally modified (PTM) auto-antigenomes
Wan et al. Targeted sequencing of genomic repeat regions detects circulating cell-free Echinococcus DNA
US12247977B2 (en) Nasopharyngeal protein biomarkers of acute respiratory virus infection and methods of using same
Liu et al. Serum antibody repertoire profiling using in silico antigen screen
WO2018149186A1 (zh) 一种acpa阴性的ra诊断标志物及其应用
US20230024898A1 (en) Immunome wide association studies to identify condition-specific antigens
US11079389B2 (en) System and method for identification of a synthetic classifer
WO2018149185A1 (zh) 一种acpa阴性的ra诊断标志物及其应用
US12297564B2 (en) Quality control reagents and methods for serum antibody profiling
US20230288421A1 (en) Sars-cov-2 serum antibody profiling
US9672324B1 (en) Peptide profiling and monitoring humoral immunity
US20240241131A1 (en) Global protein-based immunome wide association studies
CN119265302A (zh) 用于诊断肝癌的生物标志物组合、Logistics模型及其应用
CN118345160A (zh) 肺腺癌预后标志物及其应用
US20240192208A1 (en) Serum antibody profiling for leptospirosis
TWI918468B (zh) 檢測類風濕性關節炎患者對接受Janus激酶抑製劑治療的療效反應的方法
CN116643038B (zh) 一种用于评价covid-19疫苗免疫状态标志物及其应用
JP7575375B2 (ja) 関節リウマチ自己抗体レパートリーのプロファイリング及びそのためのペプチド分類子
US20140018245A1 (en) Marker sequences for multiple sclerosis and use thereof
Xie et al. Filtering of artificial chimeric reads generated by ligation preparation method of nanopore sequencing
US20180321244A1 (en) Method for Detection And Diagnosis of Oral Cancer in a sample
WO2021152586A1 (en) Methods of analyzing microbiome, immunoglobulin profile and physiological state
US20180112210A1 (en) Broad-spectrum serological diagnostics and uses thereof

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220315

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230619

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20230619

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20231204

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240808

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20250130