JP2022532790A - 固体形態 - Google Patents

固体形態 Download PDF

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Publication number
JP2022532790A
JP2022532790A JP2021568766A JP2021568766A JP2022532790A JP 2022532790 A JP2022532790 A JP 2022532790A JP 2021568766 A JP2021568766 A JP 2021568766A JP 2021568766 A JP2021568766 A JP 2021568766A JP 2022532790 A JP2022532790 A JP 2022532790A
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JP
Japan
Prior art keywords
present disclosure
ray
compound
powder
peaks
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JP2021568766A
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English (en)
Japanese (ja)
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JPWO2020236948A5 (https=
JP2022532790A5 (https=
Inventor
チャベス，メアリー
ケリー，ロン・シー
アガルワル，パラシェント
ペアレント，スティーブン・ディー
リード，ダーレン・レナード
シマノビッチ，ロマン
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アムジエン・インコーポレーテツド
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Publication of JP2022532790A publication Critical patent/JP2022532790A/ja
Publication of JPWO2020236948A5 publication Critical patent/JPWO2020236948A5/ja
Publication of JP2022532790A5 publication Critical patent/JP2022532790A5/ja
Priority to JP2025080319A priority Critical patent/JP2025131597A/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
JP2021568766A 2019-05-21 2020-05-20 固体形態 Pending JP2022532790A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025080319A JP2025131597A (ja) 2019-05-21 2025-05-13 固体形態

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962851049P 2019-05-21 2019-05-21
US62/851,049 2019-05-21
PCT/US2020/033832 WO2020236948A1 (en) 2019-05-21 2020-05-20 Solid state forms

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025080319A Division JP2025131597A (ja) 2019-05-21 2025-05-13 固体形態

Publications (3)

Publication Number Publication Date
JP2022532790A true JP2022532790A (ja) 2022-07-19
JPWO2020236948A5 JPWO2020236948A5 (https=) 2023-05-24
JP2022532790A5 JP2022532790A5 (https=) 2023-05-24

Family

ID=71016701

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021568766A Pending JP2022532790A (ja) 2019-05-21 2020-05-20 固体形態
JP2025080319A Pending JP2025131597A (ja) 2019-05-21 2025-05-13 固体形態

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025080319A Pending JP2025131597A (ja) 2019-05-21 2025-05-13 固体形態

Country Status (10)

Country Link
US (1) US12252486B2 (https=)
EP (1) EP3972972A1 (https=)
JP (2) JP2022532790A (https=)
AR (1) AR119741A1 (https=)
AU (2) AU2020277398B2 (https=)
CA (1) CA3140394A1 (https=)
MX (2) MX2021014235A (https=)
TW (1) TW202110836A (https=)
UY (1) UY38711A (https=)
WO (1) WO2020236948A1 (https=)

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EA201992781A1 (ru) 2017-05-22 2020-04-01 Эмджен Инк. Ингибиторы g12c kras и способы их применения
MA50077A (fr) 2017-09-08 2020-07-15 Amgen Inc Inhibiteurs de kras g12c et leurs procédés d'utilisation
ES2995514T3 (en) 2018-05-04 2025-02-10 Amgen Inc Kras g12c inhibitors and methods of using the same
WO2019213516A1 (en) 2018-05-04 2019-11-07 Amgen Inc. Kras g12c inhibitors and methods of using the same
US11932633B2 (en) 2018-05-07 2024-03-19 Mirati Therapeutics, Inc. KRas G12C inhibitors
EP3790886B1 (en) 2018-05-10 2024-06-26 Amgen Inc. Kras g12c inhibitors for the treatment of cancer
ES2938987T3 (es) 2018-06-01 2023-04-18 Amgen Inc Inhibidores de KRAS G12c y métodos de uso de los mismos
US20190375749A1 (en) 2018-06-11 2019-12-12 Amgen Inc. Kras g12c inhibitors and methods of using the same
ES3060664T3 (en) 2018-06-12 2026-03-27 Amgen Inc Kras g12c inhibitors encompassing a piperazine ring and use thereof in the treatment of cancer
SMT202500028T1 (it) 2018-09-10 2025-03-12 Mirati Therapeutics Inc Terapie combinate
CA3112043A1 (en) 2018-09-10 2020-03-19 Mirati Therapeutics, Inc. Combination therapies
WO2020055761A1 (en) 2018-09-10 2020-03-19 Mirati Therapeutics, Inc. Combination therapies
JP2022500385A (ja) 2018-09-10 2022-01-04 ミラティ セラピューティクス， インコーポレイテッド 組み合わせ療法
JP7516029B2 (ja) 2018-11-16 2024-07-16 アムジエン・インコーポレーテツド Ｋｒａｓ ｇ１２ｃ阻害剤化合物の重要な中間体の改良合成法
US11053226B2 (en) 2018-11-19 2021-07-06 Amgen Inc. KRAS G12C inhibitors and methods of using the same
JP7377679B2 (ja) 2018-11-19 2023-11-10 アムジエン・インコーポレーテツド がん治療のためのｋｒａｓｇ１２ｃ阻害剤及び１種以上の薬学的に活性な追加の薬剤を含む併用療法
CN113164418A (zh) 2018-12-05 2021-07-23 米拉蒂治疗股份有限公司 组合疗法
WO2020146613A1 (en) 2019-01-10 2020-07-16 Mirati Therapeutics, Inc. Kras g12c inhibitors
EP3738593A1 (en) 2019-05-14 2020-11-18 Amgen, Inc Dosing of kras inhibitor for treatment of cancers
NZ782284A (en) 2019-05-21 2024-11-29 Amgen Inc Solid state forms
AU2020277398B2 (en) 2019-05-21 2026-01-29 Amgen Inc. Solid state forms
WO2021041671A1 (en) 2019-08-29 2021-03-04 Mirati Therapeutics, Inc. Kras g12d inhibitors
US12122787B2 (en) 2019-09-20 2024-10-22 Shanghai Jemincare Pharmaceuticals Co., Ltd Fused pyridone compound, and preparation method therefor and use thereof
CN114761012B (zh) 2019-09-24 2025-03-21 米拉蒂治疗股份有限公司 组合疗法
PH12022551513A1 (en) 2019-12-20 2023-04-24 Mirati Therapeutics Inc Sos1 inhibitors
WO2021236920A1 (en) * 2020-05-20 2021-11-25 Teva Pharmaceuticals International Gmbh Solid state forms of amg-510 and process for preparation thereof
WO2021249563A1 (zh) * 2020-06-12 2021-12-16 苏州泽璟生物制药股份有限公司 芳基或杂芳基并吡啶酮或嘧啶酮类衍生物及其制备方法和应用
WO2022056307A1 (en) 2020-09-11 2022-03-17 Mirati Therapeutics, Inc. Crystalline forms of a kras g12c inhibitor
HRP20251311T1 (hr) * 2020-11-26 2026-02-27 Shanghai Hansoh Biomedical Co., Ltd. Sol i kristalni oblik heterocikličkog derivata koji sadrži dušik, metoda njihove pripreme i njihova primjena
WO2022132200A1 (en) 2020-12-15 2022-06-23 Mirati Therapeutics, Inc. Azaquinazoline pan-kras inhibitors
EP4262803A4 (en) 2020-12-16 2025-03-12 Mirati Therapeutics, Inc. Tetrahydropyridopyrimidine pan-kras inhibitors
WO2022246069A1 (en) 2021-05-19 2022-11-24 Teva Pharmaceuticals International Gmbh Process for preparation of sotorasib and solid state form thereof
CN114605406B (zh) * 2021-09-18 2023-05-26 都创(上海)医药开发有限公司 Amg510化合物的晶型及其制备方法和用途
CN115368358A (zh) * 2022-09-01 2022-11-22 浙江九洲药业股份有限公司 一种Sotorasib新晶型及其制备方法与应用

Citations (2)

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JP2019031476A (ja) * 2017-05-22 2019-02-28 アムジエン・インコーポレーテツド Ｋｒａｓ ｇ１２ｃ阻害剤及びその使用方法
WO2019051291A1 (en) * 2017-09-08 2019-03-14 Amgen Inc. Inhibitors of kras g12c and methods of using the same

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AU2014331794C1 (en) 2013-10-10 2019-09-12 Araxes Pharma Llc Inhibitors of KRAS G12C
JO3556B1 (ar) 2014-09-18 2020-07-05 Araxes Pharma Llc علاجات مدمجة لمعالجة السرطان
JP2018513853A (ja) 2015-04-10 2018-05-31 アラクセス ファーマ エルエルシー 置換キナゾリン化合物およびその使用方法
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WO2018119183A2 (en) 2016-12-22 2018-06-28 Amgen Inc. Kras g12c inhibitors and methods of using the same
WO2019213516A1 (en) 2018-05-04 2019-11-07 Amgen Inc. Kras g12c inhibitors and methods of using the same
JP7516029B2 (ja) 2018-11-16 2024-07-16 アムジエン・インコーポレーテツド Ｋｒａｓ ｇ１２ｃ阻害剤化合物の重要な中間体の改良合成法
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Also Published As

Publication number Publication date
AU2020277398B2 (en) 2026-01-29
TW202110836A (zh) 2021-03-16
MX2025010774A (es) 2025-10-01
WO2020236948A1 (en) 2020-11-26
US20220235045A1 (en) 2022-07-28
US12252486B2 (en) 2025-03-18
AU2020277398A1 (en) 2021-12-09
MX2021014235A (es) 2022-03-11
AR119741A1 (es) 2022-01-05
AU2026200455A1 (en) 2026-02-12
JP2025131597A (ja) 2025-09-09
CA3140394A1 (en) 2020-11-26
UY38711A (es) 2020-11-30
EP3972972A1 (en) 2022-03-30

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