JP2022526014A5 - - Google Patents

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Publication number
JP2022526014A5
JP2022526014A5 JP2021559817A JP2021559817A JP2022526014A5 JP 2022526014 A5 JP2022526014 A5 JP 2022526014A5 JP 2021559817 A JP2021559817 A JP 2021559817A JP 2021559817 A JP2021559817 A JP 2021559817A JP 2022526014 A5 JP2022526014 A5 JP 2022526014A5
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JP
Japan
Prior art keywords
appears
following structure
independently
bond
compound according
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2021559817A
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English (en)
Japanese (ja)
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JP7603918B2 (ja
JP2022526014A (ja
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Priority claimed from PCT/US2020/027750 external-priority patent/WO2020210689A1/en
Publication of JP2022526014A publication Critical patent/JP2022526014A/ja
Publication of JP2022526014A5 publication Critical patent/JP2022526014A5/ja
Priority to JP2024216317A priority Critical patent/JP7903604B2/ja
Application granted granted Critical
Publication of JP7603918B2 publication Critical patent/JP7603918B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021559817A 2019-04-11 2020-04-10 プログラム可能なポリマー薬 Active JP7603918B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024216317A JP7903604B2 (ja) 2019-04-11 2024-12-11 プログラム可能なポリマー薬

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962832723P 2019-04-11 2019-04-11
US62/832,723 2019-04-11
US201962877144P 2019-07-22 2019-07-22
US62/877,144 2019-07-22
PCT/US2020/027750 WO2020210689A1 (en) 2019-04-11 2020-04-10 Programmable polymeric drugs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024216317A Division JP7903604B2 (ja) 2019-04-11 2024-12-11 プログラム可能なポリマー薬

Publications (3)

Publication Number Publication Date
JP2022526014A JP2022526014A (ja) 2022-05-20
JP2022526014A5 true JP2022526014A5 (enExample) 2024-07-11
JP7603918B2 JP7603918B2 (ja) 2024-12-23

Family

ID=70476549

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021559817A Active JP7603918B2 (ja) 2019-04-11 2020-04-10 プログラム可能なポリマー薬
JP2024216317A Active JP7903604B2 (ja) 2019-04-11 2024-12-11 プログラム可能なポリマー薬

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024216317A Active JP7903604B2 (ja) 2019-04-11 2024-12-11 プログラム可能なポリマー薬

Country Status (6)

Country Link
US (1) US20220160887A1 (enExample)
EP (1) EP3952916A1 (enExample)
JP (2) JP7603918B2 (enExample)
KR (1) KR20210152523A (enExample)
CN (1) CN114430738A (enExample)
WO (1) WO2020210689A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3019559A4 (en) 2013-08-22 2017-04-05 Sony Corporation Water soluble fluorescent or colored dyes and methods for their use
WO2016138461A1 (en) 2015-02-26 2016-09-01 Sony Corporation Water soluble fluorescent or colored dyes comprising conjugating groups
KR102646956B1 (ko) 2015-02-26 2024-03-14 소니그룹주식회사 페닐에티닐나프탈렌 염료 및 이의 사용 방법
KR102765335B1 (ko) 2015-05-11 2025-02-13 소니그룹주식회사 초휘도 이량체성 또는 중합체성 염료
EP3436528B1 (en) 2016-04-01 2025-07-02 Sony Group Corporation Ultra bright dimeric or polymeric dyes with rigid spacing groups
BR112018070164B1 (pt) 2016-04-01 2022-09-27 Sony Corporation Of America Corantes diméricos ou poliméricos ultrabrilhantes
CN109153860B (zh) 2016-04-06 2021-04-23 索尼公司 具有间隔连接体基团的超高亮二聚体或聚合物染料
WO2017189805A1 (en) 2016-04-27 2017-11-02 Abbvie Inc. Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies
BR112018073199A2 (pt) 2016-05-11 2019-04-16 Sony Corporation corantes diméricos ou poliméricos ultrabrilhantes
WO2018022925A1 (en) 2016-07-29 2018-02-01 Sony Corporation Ultra bright dimeric or polymeric dyes and methods for preparation of the same
KR20260011205A (ko) 2017-10-05 2026-01-22 소니그룹주식회사 프로그램가능한 중합체성 약물
CN111836645A (zh) 2017-11-16 2020-10-27 索尼公司 可编程的聚合药物
WO2019140128A1 (en) 2018-01-12 2019-07-18 Sony Corporation Phosphoalkyl polymers comprising biologically active compounds
EP3737417B1 (en) 2018-01-12 2025-08-27 Sony Group Corporation Phosphoalkyl ribose polymers comprising biologically active compounds
US12076407B2 (en) 2018-01-12 2024-09-03 Sony Group Corporation Polymers with rigid spacing groups comprising biologically active compounds
EP3769085B1 (en) 2018-03-19 2022-08-24 Sony Group Corporation Use of divalent metals for enhancement of fluorescent signals
KR102864292B1 (ko) 2018-03-21 2025-09-26 소니그룹주식회사 링커 군을 갖는 중합체성 텐덤 염료
JP7580689B2 (ja) 2018-06-27 2024-11-12 ソニーグループ株式会社 デオキシリボースを含むリンカー基を有するポリマー色素
US12578342B2 (en) 2018-07-13 2026-03-17 Sony Group Corporation Polymeric dyes having a backbone comprising organophosphate units
EP3861074A2 (en) 2019-09-26 2021-08-11 Sony Group Corporation Polymeric tandem dyes with linker groups
EP4038081A1 (en) 2019-09-30 2022-08-10 Sony Group Corporation Nucleotide probes
KR20230092863A (ko) 2020-06-11 2023-06-26 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
EP4256078A1 (en) 2020-12-07 2023-10-11 Sony Group Corporation Spacing linker group design for brightness enhancement in dimeric or polymeric dyes
MX2023013851A (es) 2021-05-24 2023-12-08 Provention Bio Inc Metodos para el tratamiento de diabetes tipo 1.
US20240350645A1 (en) * 2021-07-22 2024-10-24 Sony Group Corporation Automated synthesis of polymeric drugs
CN117750977A (zh) * 2021-07-22 2024-03-22 索尼集团公司 聚合型药物的自动合成
EP4590340A1 (en) * 2022-09-22 2025-07-30 Sony Group Corporation Polymers with steroids or vitamins
CN120077057A (zh) 2022-10-04 2025-05-30 伊莱利利公司 Trem2相关疾病和病症的基因治疗
AR131035A1 (es) 2022-11-11 2025-02-12 Lilly Co Eli Ácidos nucleicos sintéticos que incluyen constructos promotores dirigidos a astrocitos y métodos de uso de los mismos
WO2026043765A1 (en) 2024-08-21 2026-02-26 Eli Lilly And Company Engineered regulatory splice elements for gene therapies

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9545447B2 (en) * 2013-01-04 2017-01-17 The Texas A&M University System Polymer-drug systems
EP3019559A4 (en) * 2013-08-22 2017-04-05 Sony Corporation Water soluble fluorescent or colored dyes and methods for their use
WO2016138461A1 (en) 2015-02-26 2016-09-01 Sony Corporation Water soluble fluorescent or colored dyes comprising conjugating groups
KR102765335B1 (ko) * 2015-05-11 2025-02-13 소니그룹주식회사 초휘도 이량체성 또는 중합체성 염료
JP6817288B2 (ja) * 2015-08-10 2021-01-20 ハンジョウ ディーエーシー バイオテック シーオー.,エルティディ.Hangzhou Dac Biotech Co.,Ltd. 新規な連結体及び生体分子と薬物との特異的共役におけるその使用
EP3436528B1 (en) * 2016-04-01 2025-07-02 Sony Group Corporation Ultra bright dimeric or polymeric dyes with rigid spacing groups
BR112018070164B1 (pt) * 2016-04-01 2022-09-27 Sony Corporation Of America Corantes diméricos ou poliméricos ultrabrilhantes
CN109153860B (zh) * 2016-04-06 2021-04-23 索尼公司 具有间隔连接体基团的超高亮二聚体或聚合物染料
US11390754B2 (en) * 2016-05-10 2022-07-19 Sony Corporation Compositions comprising a polymeric dye and a cyclodextrin and uses thereof
BR112018073199A2 (pt) * 2016-05-11 2019-04-16 Sony Corporation corantes diméricos ou poliméricos ultrabrilhantes
WO2018022925A1 (en) * 2016-07-29 2018-02-01 Sony Corporation Ultra bright dimeric or polymeric dyes and methods for preparation of the same
KR20260011205A (ko) * 2017-10-05 2026-01-22 소니그룹주식회사 프로그램가능한 중합체성 약물
US12290571B2 (en) * 2017-10-05 2025-05-06 Sony Group Corporation Programmable dendritic drugs
CN111836645A (zh) * 2017-11-16 2020-10-27 索尼公司 可编程的聚合药物
EP3737417B1 (en) * 2018-01-12 2025-08-27 Sony Group Corporation Phosphoalkyl ribose polymers comprising biologically active compounds
US12076407B2 (en) * 2018-01-12 2024-09-03 Sony Group Corporation Polymers with rigid spacing groups comprising biologically active compounds
EP3769085B1 (en) * 2018-03-19 2022-08-24 Sony Group Corporation Use of divalent metals for enhancement of fluorescent signals
KR102864292B1 (ko) * 2018-03-21 2025-09-26 소니그룹주식회사 링커 군을 갖는 중합체성 텐덤 염료
JP7580689B2 (ja) * 2018-06-27 2024-11-12 ソニーグループ株式会社 デオキシリボースを含むリンカー基を有するポリマー色素
EP3861074A2 (en) * 2019-09-26 2021-08-11 Sony Group Corporation Polymeric tandem dyes with linker groups

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