JP2022524692A5 - - Google Patents

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Publication number
JP2022524692A5
JP2022524692A5 JP2021539095A JP2021539095A JP2022524692A5 JP 2022524692 A5 JP2022524692 A5 JP 2022524692A5 JP 2021539095 A JP2021539095 A JP 2021539095A JP 2021539095 A JP2021539095 A JP 2021539095A JP 2022524692 A5 JP2022524692 A5 JP 2022524692A5
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JP
Japan
Prior art keywords
cancer
item
domain
tcrβv
cells
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Granted
Application number
JP2021539095A
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English (en)
Japanese (ja)
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JP2022524692A (ja
JP7700039B2 (ja
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Application filed filed Critical
Priority claimed from PCT/US2020/012162 external-priority patent/WO2020142672A2/en
Publication of JP2022524692A publication Critical patent/JP2022524692A/ja
Publication of JP2022524692A5 publication Critical patent/JP2022524692A5/ja
Application granted granted Critical
Publication of JP7700039B2 publication Critical patent/JP7700039B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021539095A 2019-01-04 2020-01-03 抗tcr抗体分子およびその使用 Active JP7700039B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962788497P 2019-01-04 2019-01-04
US62/788,497 2019-01-04
US201962803893P 2019-02-11 2019-02-11
US62/803,893 2019-02-11
PCT/US2020/012162 WO2020142672A2 (en) 2019-01-04 2020-01-03 Anti-tcr antibody molecules and uses thereof

Publications (3)

Publication Number Publication Date
JP2022524692A JP2022524692A (ja) 2022-05-10
JP2022524692A5 true JP2022524692A5 (enExample) 2023-03-06
JP7700039B2 JP7700039B2 (ja) 2025-06-30

Family

ID=71407087

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021539095A Active JP7700039B2 (ja) 2019-01-04 2020-01-03 抗tcr抗体分子およびその使用

Country Status (8)

Country Link
US (1) US20220064255A1 (enExample)
EP (1) EP3906057A4 (enExample)
JP (1) JP7700039B2 (enExample)
CN (1) CN113543807A (enExample)
AU (2) AU2020204686A1 (enExample)
CA (1) CA3125345A1 (enExample)
GB (1) GB2595980B (enExample)
WO (1) WO2020142672A2 (enExample)

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JP7685735B2 (ja) 2016-12-02 2025-05-30 アンヘレス セラピューティクス インコーポレイテッド 合成免疫受容体およびその使用方法
WO2019139987A1 (en) 2018-01-09 2019-07-18 Elstar Therapeutics, Inc. Calreticulin binding constructs and engineered t cells for the treatment of diseases
US12152073B2 (en) 2018-03-14 2024-11-26 Marengo Therapeutics, Inc. Multifunctional molecules that bind to calreticulin and uses thereof
WO2020010250A2 (en) 2018-07-03 2020-01-09 Elstar Therapeutics, Inc. Anti-tcr antibody molecules and uses thereof
AU2020226893B2 (en) 2019-02-21 2025-02-27 Marengo Therapeutics, Inc. Multifunctional molecules that bind to T cell related cancer cells and uses thereof
GB2597851B (en) 2019-02-21 2024-05-29 Marengo Therapeutics Inc Antibody molecules that bind to NKP30 and uses thereof
CN113874400B (zh) 2019-03-11 2025-02-07 詹森生物科技公司 抗Vβ17/抗CD123双特异性抗体
JP7590430B2 (ja) * 2019-11-14 2024-11-26 マレンゴ・セラピューティクス,インコーポレーテッド 抗tcr抗体分子およびその使用
AU2020416273A1 (en) * 2020-01-03 2022-07-28 Marengo Therapeutics, Inc. Anti-TCR antibody molecules and uses thereof
US20230285586A1 (en) * 2020-07-23 2023-09-14 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US20230346966A1 (en) * 2020-07-23 2023-11-02 Dyne Therapeutics, Inc. Muscle-targeting complexes and uses thereof in treating muscle atrophy
AU2021313058A1 (en) * 2020-07-23 2023-03-30 Dyne Therapeutics, Inc. Muscle-targeting complexes and uses thereof
CA3190987A1 (en) * 2020-08-10 2022-02-17 Janssen Biotech, Inc. Materials and methods for producing bioengineered virus specific lymphocytes
US12448449B2 (en) 2020-09-11 2025-10-21 Janssen Biotech, Inc. Immune targeting molecules and uses thereof
AU2021339754A1 (en) * 2020-09-11 2023-05-25 Janssen Biotech, Inc. Methods and compositions for modulating beta chain mediated immunity
US20220089737A1 (en) * 2020-09-11 2022-03-24 Janssen Biotech, Inc. Multi-specific immune targeting molecules and uses thereof
BR112023022975A2 (pt) 2021-05-05 2024-01-23 Immatics Biotechnologies Gmbh Polipeptídeos de ligação ao antígeno bma031 melhorados
CN115820697B (zh) * 2022-09-23 2024-07-30 中国海洋大学 一种免疫细胞及其制备方法和应用
JP2026501572A (ja) * 2022-12-27 2026-01-16 イェール ユニバーシティー Tcr-vbeta特異的治療用分子、及びその使用
WO2024140981A1 (zh) * 2022-12-30 2024-07-04 上药生物治疗(香港)有限公司 细胞原位分泌抗体及其用途
WO2024197082A2 (en) * 2023-03-21 2024-09-26 Marengo Therapeutics, Inc. Tcr targeting molecules and uses thereof
AU2024240821A1 (en) 2023-03-23 2025-11-06 Bodhi Bio Llc Compositions and methods for antigen-specific therapy
EP4704897A1 (en) * 2023-04-27 2026-03-11 Marengo Therapeutics, Inc. Combination therapies using molecules binding to tcr
WO2025050088A1 (en) * 2023-08-31 2025-03-06 Adaptive Biotechnologies Corporation Agents and methods for preventing or inhibiting adaptive immune responses associated with multiple sclerosis
WO2025051339A1 (en) * 2023-09-05 2025-03-13 Tiber Biotech Srl SINGLE-CHAIN VARIABLE FRAGMENT AND MOLECULES DERIVING THEREFROM THAT BIND FRAGMENT TRVB5-1 OF THE β CHAIN OF HUMAN T-CELL RECEPTOR
WO2026011097A1 (en) * 2024-07-03 2026-01-08 Yale University Antibody drug conjugates comprising tcr-vbeta specific therapeutic molecules and uses thereof
CN120064640B (zh) * 2025-01-15 2026-01-23 中牧实业股份有限公司 一种猪细小病毒vp2双抗体夹心定量检测试剂盒及其应用

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Publication number Priority date Publication date Assignee Title
US5766947A (en) * 1988-12-14 1998-06-16 Astra Ab Monoclonal antibodies reactive with an epitope of a Vβ3.1 variable region of a T cell receptor
JPH0787994A (ja) * 1993-04-30 1995-04-04 Sumitomo Electric Ind Ltd T細胞抗原受容体Vβ22に対するモノクローナル抗体及びその製造方法
IL125747A0 (en) * 1996-10-04 1999-04-11 Univ Jefferson T cells mediating an immune response and methods of use
CA2625222A1 (en) * 2005-10-11 2007-04-19 Domantis Limited Antibody polypeptide library screening and selected antibody polypeptides
US20130273089A1 (en) * 2011-11-03 2013-10-17 Tolera Therapeutics, Inc. Antibody and methods for selective inhibition of t-cell responses
EP3593812A3 (en) * 2014-03-15 2020-05-27 Novartis AG Treatment of cancer using chimeric antigen receptor
SG10201913680PA (en) * 2014-05-29 2020-03-30 Macrogenics Inc Tri-specific binding molecules that specifically bind to multiple cancer antigens and methods of use thereof
PT3294768T (pt) * 2015-05-13 2019-11-05 Ablynx Nv Polipétidos de recrutamento de células t com base na reatividade do tcr alfa/beta
US20180256716A1 (en) * 2015-06-01 2018-09-13 Medigene Immunotherapies Gmbh T-cell receptor specific antibodies
CN116334205A (zh) * 2015-09-03 2023-06-27 诺华股份有限公司 预测细胞因子释放综合征的生物标志物
AU2017363311A1 (en) * 2016-11-22 2019-06-13 TCR2 Therapeutics Inc. Compositions and methods for TCR reprogramming using fusion proteins
WO2020010250A2 (en) * 2018-07-03 2020-01-09 Elstar Therapeutics, Inc. Anti-tcr antibody molecules and uses thereof

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