JP2022521491A5 - - Google Patents

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Publication number
JP2022521491A5
JP2022521491A5 JP2021547567A JP2021547567A JP2022521491A5 JP 2022521491 A5 JP2022521491 A5 JP 2022521491A5 JP 2021547567 A JP2021547567 A JP 2021547567A JP 2021547567 A JP2021547567 A JP 2021547567A JP 2022521491 A5 JP2022521491 A5 JP 2022521491A5
Authority
JP
Japan
Prior art keywords
clause
degrees
pharmaceutically acceptable
item
crystalline form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021547567A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022521491A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/018185 external-priority patent/WO2020168125A1/en
Publication of JP2022521491A publication Critical patent/JP2022521491A/ja
Publication of JP2022521491A5 publication Critical patent/JP2022521491A5/ja
Pending legal-status Critical Current

Links

JP2021547567A 2019-02-13 2020-02-13 タンパク質アルギニンメチルトランスフェラーゼ5(prmt5)の選択的阻害剤 Pending JP2022521491A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962805175P 2019-02-13 2019-02-13
US62/805,175 2019-02-13
US201962805726P 2019-02-14 2019-02-14
US62/805,726 2019-02-14
PCT/US2020/018185 WO2020168125A1 (en) 2019-02-13 2020-02-13 Selective inhibitor of protein arginine methyltransferase 5 (prmt5)

Publications (2)

Publication Number Publication Date
JP2022521491A JP2022521491A (ja) 2022-04-08
JP2022521491A5 true JP2022521491A5 (https=) 2023-02-21

Family

ID=69845552

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021547567A Pending JP2022521491A (ja) 2019-02-13 2020-02-13 タンパク質アルギニンメチルトランスフェラーゼ5(prmt5)の選択的阻害剤

Country Status (12)

Country Link
US (1) US20220160713A1 (https=)
EP (1) EP3924360A1 (https=)
JP (1) JP2022521491A (https=)
KR (1) KR20210129051A (https=)
CN (1) CN113811539A (https=)
AU (1) AU2020223058A1 (https=)
BR (1) BR112021015796A2 (https=)
CA (1) CA3129612A1 (https=)
IL (1) IL285536A (https=)
MX (1) MX2021009796A (https=)
WO (1) WO2020168125A1 (https=)
ZA (1) ZA202105887B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11077101B1 (en) 2018-07-18 2021-08-03 Tango Therapeutics, Inc. Compounds and methods of use
US12403137B2 (en) 2019-10-28 2025-09-02 Tango Therapeutics, Inc. Compounds and methods of use
WO2022026892A1 (en) 2020-07-31 2022-02-03 Tango Therapeutics, Inc. Piperidin-1- yl-n-pyrydi ne-3-yl-2-oxoacet am ide derivatives useful for the treatment of mtap-deficient and/or mt a-accumulating cancers
US20220251088A1 (en) * 2020-12-10 2022-08-11 Prelude Therapeutics, Incorporated Processes for Making PRMT5 Inhibitors

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657744A (en) 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US5040548A (en) 1989-06-01 1991-08-20 Yock Paul G Angioplasty mehtod
US5350395A (en) 1986-04-15 1994-09-27 Yock Paul G Angioplasty apparatus facilitating rapid exchanges
US5061273A (en) 1989-06-01 1991-10-29 Yock Paul G Angioplasty apparatus facilitating rapid exchanges
US4748982A (en) 1987-01-06 1988-06-07 Advanced Cardiovascular Systems, Inc. Reinforced balloon dilatation catheter with slitted exchange sleeve and method
US5001139A (en) 1987-06-12 1991-03-19 American Cyanamid Company Enchancers for the transdermal flux of nivadipine
US4992445A (en) 1987-06-12 1991-02-12 American Cyanamid Co. Transdermal delivery of pharmaceuticals
CA1322628C (en) 1988-10-04 1993-10-05 Richard A. Schatz Expandable intraluminal graft
US5674278A (en) 1989-08-24 1997-10-07 Arterial Vascular Engineering, Inc. Endovascular support device
US5292331A (en) 1989-08-24 1994-03-08 Applied Vascular Engineering, Inc. Endovascular support device
US6344053B1 (en) 1993-12-22 2002-02-05 Medtronic Ave, Inc. Endovascular support device and method
US20170198006A1 (en) * 2014-06-25 2017-07-13 Epizyme, Inc. Prmt5 inhibitors and uses thereof
WO2016044576A1 (en) * 2014-09-17 2016-03-24 Epizyme, Inc. Salts, co-crystals, amorphous forms, and crystalline forms of an arginine methyltransferase inhibitor
MX2017010844A (es) * 2015-02-24 2017-12-07 Pfizer Derivados de nucleosidos sustituidos utiles como agentes anticancerosos.
MA41828A (fr) * 2015-03-27 2018-01-30 Pharmacyclics Llc Co-cristaux d'un inhibiteur de la tyrosine kinase de bruton
AR104326A1 (es) * 2015-05-04 2017-07-12 Lilly Co Eli Compuestos nucleósidos 5-sustituidos
TWI870767B (zh) * 2015-08-26 2025-01-21 比利時商健生藥品公司 使用作為prmt5抑制劑之新穎經6-6雙環芳香環取代之核苷類似物
EP3939986A1 (en) * 2017-08-09 2022-01-19 Prelude Therapeutics, Incorporated Selective inhibitors of protein arginine methyltransferase 5 (prmt5)
US12552826B2 (en) * 2018-08-07 2026-02-17 Merck Sharp & Dohme Llc PRMT5 inhibitors

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