JP2022512921A5 - - Google Patents
Info
- Publication number
- JP2022512921A5 JP2022512921A5 JP2021524058A JP2021524058A JP2022512921A5 JP 2022512921 A5 JP2022512921 A5 JP 2022512921A5 JP 2021524058 A JP2021524058 A JP 2021524058A JP 2021524058 A JP2021524058 A JP 2021524058A JP 2022512921 A5 JP2022512921 A5 JP 2022512921A5
- Authority
- JP
- Japan
- Prior art keywords
- primate
- cell differentiation
- composition according
- hair cell
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862756910P | 2018-11-07 | 2018-11-07 | |
| US62/756,910 | 2018-11-07 | ||
| US201962888105P | 2019-08-16 | 2019-08-16 | |
| US62/888,105 | 2019-08-16 | ||
| PCT/US2019/060324 WO2020097369A1 (en) | 2018-11-07 | 2019-11-07 | Compositions and methods of inducing differentiation of a hair cell |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022512921A JP2022512921A (ja) | 2022-02-07 |
| JP2022512921A5 true JP2022512921A5 (enExample) | 2022-12-28 |
Family
ID=70611182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021524058A Pending JP2022512921A (ja) | 2018-11-07 | 2019-11-07 | 有毛細胞の分化を誘導する組成物及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220395582A1 (enExample) |
| EP (1) | EP3880827A4 (enExample) |
| JP (1) | JP2022512921A (enExample) |
| CN (1) | CN113874512A (enExample) |
| AU (1) | AU2019376084A1 (enExample) |
| CA (1) | CA3119059A1 (enExample) |
| WO (1) | WO2020097369A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020160371A1 (en) | 2019-02-01 | 2020-08-06 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| CA3141807A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| US12534709B2 (en) | 2019-05-31 | 2026-01-27 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| WO2021262676A1 (en) * | 2020-06-23 | 2021-12-30 | Children's Hospital Medical Center | Model for insulin resistance |
| CA3219054A1 (en) * | 2021-05-05 | 2022-11-10 | Decibel Therapeutics, Inc. | Compositions and methods for treating sensorineural hearing loss using stereocilin dual vector systems |
| JP2025503508A (ja) * | 2021-12-23 | 2025-02-04 | ユニバーシティ オブ ロチェスター | 内耳への薬剤の送達のための組成物及び方法 |
| KR20260105793A (ko) * | 2023-10-31 | 2026-07-07 | 씨티엔엔비원 파운데이션 | 유전자 치료 구조체 및 이의 사용 방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200100916T2 (enExample) * | 1998-07-14 | 2002-06-21 | Corixa@@Corporation | |
| US20040166091A1 (en) * | 2003-02-24 | 2004-08-26 | Genvec, Inc. | Materials and methods for treating disorders of the ear |
| US20050281786A1 (en) * | 2004-06-18 | 2005-12-22 | David Poulsen | AAV mediated gene delivery to cochlear cells |
| CA2801535C (en) * | 2010-06-04 | 2017-05-30 | Hough Ear Institute | Composition and method for inner ear sensory hair cell regeneration or replacement |
| WO2013020097A1 (en) * | 2011-08-03 | 2013-02-07 | Quark Pharmaceuticals, Inc. | Double-stranded oligonucleotide compounds for treating hearing and balance disorders |
| DK2986635T3 (en) * | 2013-04-18 | 2019-01-28 | Fond Telethon | EFFECTIVE DELIVERY OF BIG GENES THROUGH DUAL-AAV VECTORS |
| JP2015534818A (ja) * | 2013-11-04 | 2015-12-07 | ジェネシス リサーチ インスティチュート | 聴覚を治療するための組成物および方法 |
| CA3007476A1 (en) * | 2015-12-11 | 2017-06-15 | Massachusetts Eye And Ear Infirmary | Materials and methods for delivering nucleic acids to cochlear and vestibular cells |
| EP3393522B1 (en) * | 2015-12-22 | 2021-07-07 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Improved hybrid dual recombinant aav vector systems for gene therapy |
| WO2017136764A1 (en) * | 2016-02-05 | 2017-08-10 | The General Hospital Corporation | Hybrid system for efficient gene delivery to cells of the inner ear |
| US20190142969A1 (en) * | 2016-04-26 | 2019-05-16 | Massachusetts Eye And Ear Infirmary | ISL1-Based Gene Therapy to Treat Hearing Loss |
| WO2018039375A1 (en) * | 2016-08-23 | 2018-03-01 | Akouos, Inc. | Compositions and methods for treating non-age-associated hearing impairment in a human subject |
| US12534739B2 (en) * | 2018-10-11 | 2026-01-27 | Decibel Therapeutics, Inc. | AAV1 vectors and uses thereof for treatment of otic indications |
| CN110437317B (zh) * | 2019-01-30 | 2023-05-02 | 上海科技大学 | 具有变异衣壳蛋白的腺相关病毒及其用途 |
-
2019
- 2019-11-07 EP EP19882633.1A patent/EP3880827A4/en not_active Withdrawn
- 2019-11-07 CN CN201980087541.3A patent/CN113874512A/zh active Pending
- 2019-11-07 US US17/291,906 patent/US20220395582A1/en not_active Abandoned
- 2019-11-07 WO PCT/US2019/060324 patent/WO2020097369A1/en not_active Ceased
- 2019-11-07 CA CA3119059A patent/CA3119059A1/en active Pending
- 2019-11-07 AU AU2019376084A patent/AU2019376084A1/en not_active Abandoned
- 2019-11-07 JP JP2021524058A patent/JP2022512921A/ja active Pending
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