JP2022509589A - 機械学習技術を使用するナノ細孔シグナルの分析 - Google Patents
機械学習技術を使用するナノ細孔シグナルの分析 Download PDFInfo
- Publication number
- JP2022509589A JP2022509589A JP2021525061A JP2021525061A JP2022509589A JP 2022509589 A JP2022509589 A JP 2022509589A JP 2021525061 A JP2021525061 A JP 2021525061A JP 2021525061 A JP2021525061 A JP 2021525061A JP 2022509589 A JP2022509589 A JP 2022509589A
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- label
- labels
- polymer unit
- unit type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F18/00—Pattern recognition
- G06F18/20—Analysing
- G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
- G06F18/214—Generating training patterns; Bootstrap methods, e.g. bagging or boosting
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N20/00—Machine learning
- G06N20/20—Ensemble learning
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N3/00—Computing arrangements based on biological models
- G06N3/02—Neural networks
- G06N3/04—Architecture, e.g. interconnection topology
- G06N3/044—Recurrent networks, e.g. Hopfield networks
- G06N3/0442—Recurrent networks, e.g. Hopfield networks characterised by memory or gating, e.g. long short-term memory [LSTM] or gated recurrent units [GRU]
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N3/00—Computing arrangements based on biological models
- G06N3/02—Neural networks
- G06N3/04—Architecture, e.g. interconnection topology
- G06N3/0464—Convolutional networks [CNN, ConvNet]
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N3/00—Computing arrangements based on biological models
- G06N3/02—Neural networks
- G06N3/08—Learning methods
- G06N3/084—Backpropagation, e.g. using gradient descent
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N3/00—Computing arrangements based on biological models
- G06N3/02—Neural networks
- G06N3/08—Learning methods
- G06N3/09—Supervised learning
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/165—Mathematical modelling, e.g. logarithm, ratio
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/60—Detection means characterised by use of a special device
- C12Q2565/631—Detection means characterised by use of a special device being a biochannel or pore
Landscapes
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Data Mining & Analysis (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Artificial Intelligence (AREA)
- Evolutionary Computation (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Software Systems (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Mathematical Physics (AREA)
- Computing Systems (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Computational Linguistics (AREA)
- Microbiology (AREA)
- Signal Processing (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Databases & Information Systems (AREA)
- Bioethics (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023106581A JP2023126856A (ja) | 2018-11-28 | 2023-06-29 | 機械学習技術を使用するナノ細孔シグナルの分析 |
| JP2025139101A JP2025172079A (ja) | 2018-11-28 | 2025-08-22 | 機械学習技術を使用するナノ細孔シグナルの分析 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1819378.9 | 2018-11-28 | ||
| GBGB1819378.9A GB201819378D0 (en) | 2018-11-28 | 2018-11-28 | Analysis of nanopore signal using a machine-learning technique |
| PCT/GB2019/053334 WO2020109773A1 (en) | 2018-11-28 | 2019-11-26 | Analysis of nanopore signal using a machine-learning technique |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023106581A Division JP2023126856A (ja) | 2018-11-28 | 2023-06-29 | 機械学習技術を使用するナノ細孔シグナルの分析 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2022509589A true JP2022509589A (ja) | 2022-01-21 |
Family
ID=65024631
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525061A Pending JP2022509589A (ja) | 2018-11-28 | 2019-11-26 | 機械学習技術を使用するナノ細孔シグナルの分析 |
| JP2023106581A Pending JP2023126856A (ja) | 2018-11-28 | 2023-06-29 | 機械学習技術を使用するナノ細孔シグナルの分析 |
| JP2025139101A Pending JP2025172079A (ja) | 2018-11-28 | 2025-08-22 | 機械学習技術を使用するナノ細孔シグナルの分析 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023106581A Pending JP2023126856A (ja) | 2018-11-28 | 2023-06-29 | 機械学習技術を使用するナノ細孔シグナルの分析 |
| JP2025139101A Pending JP2025172079A (ja) | 2018-11-28 | 2025-08-22 | 機械学習技術を使用するナノ細孔シグナルの分析 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12264360B2 (enExample) |
| EP (1) | EP3887543B1 (enExample) |
| JP (3) | JP2022509589A (enExample) |
| CN (1) | CN113166804A (enExample) |
| AU (1) | AU2019389841B2 (enExample) |
| BR (1) | BR112021008198A2 (enExample) |
| CA (1) | CA3118632A1 (enExample) |
| GB (1) | GB201819378D0 (enExample) |
| SG (1) | SG11202103410TA (enExample) |
| WO (1) | WO2020109773A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201222928D0 (en) | 2012-12-19 | 2013-01-30 | Oxford Nanopore Tech Ltd | Analysis of a polynucleotide |
| EP3971300B1 (en) | 2014-10-16 | 2024-06-05 | Oxford Nanopore Technologies plc | Sorting of polymers |
| GB201707138D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Machine learning analysis of nanopore measurements |
| EP3731959B1 (en) | 2017-12-29 | 2025-10-08 | Clear Labs, Inc. | Automated priming and library loading device |
| US11210554B2 (en) | 2019-03-21 | 2021-12-28 | Illumina, Inc. | Artificial intelligence-based generation of sequencing metadata |
| US11347965B2 (en) | 2019-03-21 | 2022-05-31 | Illumina, Inc. | Training data generation for artificial intelligence-based sequencing |
| US11593649B2 (en) | 2019-05-16 | 2023-02-28 | Illumina, Inc. | Base calling using convolutions |
| US11423306B2 (en) | 2019-05-16 | 2022-08-23 | Illumina, Inc. | Systems and devices for characterization and performance analysis of pixel-based sequencing |
| US10911471B1 (en) * | 2019-11-27 | 2021-02-02 | The Florida International University Board Of Trustees | Systems and methods for network-based intrusion detection |
| US12592298B2 (en) | 2020-02-20 | 2026-03-31 | Illumina, Inc. | Hardware execution and acceleration of artificial intelligence-based base caller |
| JP7747643B2 (ja) | 2020-02-20 | 2025-10-01 | イルミナ インコーポレイテッド | 人工知能ベースの多対多ベースコール |
| US12354008B2 (en) | 2020-02-20 | 2025-07-08 | Illumina, Inc. | Knowledge distillation and gradient pruning-based compression of artificial intelligence-based base caller |
| US12591780B2 (en) | 2020-02-20 | 2026-03-31 | Illumina, Inc. | Data compression for artificial intelligence-based base calling |
| WO2021214516A1 (en) * | 2020-04-21 | 2021-10-28 | Neural Concept Sa | Radius based neural network operations on sets of points |
| GB202103605D0 (en) | 2021-03-16 | 2021-04-28 | Oxford Nanopore Tech Ltd | Alignment of target and reference sequences of polymer units |
| US20220301657A1 (en) | 2021-03-16 | 2022-09-22 | Illumina, Inc. | Tile location and/or cycle based weight set selection for base calling |
| EP4309080A1 (en) * | 2021-03-16 | 2024-01-24 | Illumina Software, Inc. | Neural network parameter quantization for base calling |
| IL307398A (en) * | 2021-04-12 | 2023-12-01 | Univ Hong Kong Chinese | Base change analysis using electrical signals |
| US12217829B2 (en) | 2021-04-15 | 2025-02-04 | Illumina, Inc. | Artificial intelligence-based analysis of protein three-dimensional (3D) structures |
| US12444482B2 (en) | 2021-04-15 | 2025-10-14 | Illumina, Inc. | Multi-channel protein voxelization to predict variant pathogenicity using deep convolutional neural networks |
| US20240240248A1 (en) | 2021-05-19 | 2024-07-18 | Oxford Nanopore Technologies Plc | Methods for complement strand sequencing |
| US12530882B2 (en) | 2021-07-01 | 2026-01-20 | Illumina, Inc. | Efficient artificial intelligence-based base calling of index sequences |
| CN117063240A (zh) | 2021-12-24 | 2023-11-14 | 上海芯像生物科技有限公司 | 基于深度学习的核酸测序方法和系统 |
| EP4594523A2 (en) | 2022-09-28 | 2025-08-06 | Massachusetts Institute of Technology | High throughput stochastic bio-molecular sensor |
| GB202215442D0 (en) | 2022-10-19 | 2022-11-30 | Oxford Nanopore Tech Plc | Analysis of a polymer |
| CN120202306A (zh) | 2022-11-01 | 2025-06-24 | 牛津纳米孔科技公开有限公司 | 生化分析系统以及控制生化分析系统的方法 |
| WO2025024791A1 (en) * | 2023-07-27 | 2025-01-30 | University Of Washington | Systems and methods for mobile-enabled targeted nanopore sequencing with mobile-enabled real-time fusion detection |
| CN116884503B (zh) * | 2023-09-06 | 2023-12-26 | 北京齐碳科技有限公司 | 序列和后验矩阵的处理方法、装置和计算设备 |
| WO2026000404A1 (zh) * | 2024-06-28 | 2026-01-02 | 深圳华大生命科学研究院 | 碱基识别方法、碱基识别模型训练方法及电子设备 |
| GB2644084A (en) | 2024-09-16 | 2026-03-18 | Oxford Nanopore Tech Plc | Augmented consensus and variant calling |
| GB202413747D0 (en) | 2024-09-18 | 2024-10-30 | Oxford Nanopore Tech Plc | Preprocessing nanopore signals |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014531901A (ja) * | 2011-09-23 | 2014-12-04 | オックスフォード ナノポール テクノロジーズ リミテッド | ポリマー単位を含むポリマーの解析 |
| WO2015173587A1 (en) * | 2014-05-15 | 2015-11-19 | Oxford Nanopore Technologies Limited | Model adjustment during analysis of a polymer from nanopore measurements |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6267872B1 (en) | 1998-11-06 | 2001-07-31 | The Regents Of The University Of California | Miniature support for thin films containing single channels or nanopores and methods for using same |
| EP1192103A1 (en) | 1999-06-22 | 2002-04-03 | President And Fellows of Harvard College | Control of solid state dimensional features |
| WO2005124888A1 (en) | 2004-06-08 | 2005-12-29 | President And Fellows Of Harvard College | Suspended carbon nanotube field effect transistor |
| US20080113833A1 (en) | 2006-11-15 | 2008-05-15 | Francisco Fernandez | Methods of playing soccer games |
| EP1962392A1 (en) | 2007-02-23 | 2008-08-27 | C & C Marshall Limited | Connector |
| GB0713402D0 (en) | 2007-07-11 | 2007-08-22 | Cardiff & Vale Nhs Trust | A method of diagnosing a condition using a neural network |
| EP3540436B1 (en) | 2007-09-12 | 2023-11-01 | President And Fellows Of Harvard College | High-resolution molecular sensor |
| GB0724736D0 (en) | 2007-12-19 | 2008-01-30 | Oxford Nanolabs Ltd | Formation of layers of amphiphilic molecules |
| EP2391732B1 (en) | 2009-01-30 | 2015-05-27 | Oxford Nanopore Technologies Limited | Methods using adaptors for nucleic acid constructs in transmembrane sequencing |
| CN102482330A (zh) | 2009-01-30 | 2012-05-30 | 牛津纳米孔技术有限公司 | 酶突变体 |
| GB0905140D0 (en) | 2009-03-25 | 2009-05-06 | Isis Innovation | Method |
| CA2758617C (en) | 2009-04-20 | 2017-10-03 | Oxford Nanopore Technologies Limited | Lipid bilayer sensor array |
| AU2010307229B2 (en) | 2009-09-18 | 2016-02-25 | President And Fellows Of Harvard College | Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis |
| EP2507387B1 (en) | 2009-12-01 | 2017-01-25 | Oxford Nanopore Technologies Limited | Biochemical analysis instrument and method |
| US8828211B2 (en) | 2010-06-08 | 2014-09-09 | President And Fellows Of Harvard College | Nanopore device with graphene supported artificial lipid membrane |
| EP2614156B1 (en) | 2010-09-07 | 2018-08-01 | The Regents of The University of California | Control of dna movement in a nanopore at one nucleotide precision by a processive enzyme |
| BR112013020411B1 (pt) | 2011-02-11 | 2021-09-08 | Oxford Nanopore Technologies Limited | Monômero de msp mutante, construto, polinucleotídeo, poro, kit e aparelho para caracterizar uma sequência de ácido nucleico alvo, e, método para caracterizar uma sequência de ácido nucleico alvo |
| WO2012138357A1 (en) | 2011-04-04 | 2012-10-11 | President And Fellows Of Harvard College | Nanopore sensing by local electrical potential measurement |
| KR20140050067A (ko) | 2011-07-25 | 2014-04-28 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 막횡단 포어를 사용한 이중 가닥 폴리뉴클레오티드 서열분석을 위한 헤어핀 루프 방법 |
| EP3736339B1 (en) * | 2012-02-16 | 2022-07-27 | Oxford Nanopore Technologies plc | Analysis of measurements of a polymer |
| WO2013153359A1 (en) | 2012-04-10 | 2013-10-17 | Oxford Nanopore Technologies Limited | Mutant lysenin pores |
| US20140006308A1 (en) | 2012-06-28 | 2014-01-02 | Google Inc. | Portion-by-portion feedback for electronic books |
| GB201313121D0 (en) | 2013-07-23 | 2013-09-04 | Oxford Nanopore Tech Ltd | Array of volumes of polar medium |
| JP6375301B2 (ja) | 2012-10-26 | 2018-08-15 | オックスフォード ナノポール テクノロジーズ リミテッド | 液滴界面 |
| CN106255767A (zh) | 2014-03-21 | 2016-12-21 | 牛津楠路珀尔科技有限公司 | 由多维测量分析聚合物 |
| CN119899249A (zh) | 2014-09-01 | 2025-04-29 | 弗拉芒区生物技术研究所 | 突变csgg孔 |
| GB201508003D0 (en) | 2015-05-11 | 2015-06-24 | Oxford Nanopore Tech Ltd | Apparatus and methods for measuring an electrical current |
| GB201508669D0 (en) | 2015-05-20 | 2015-07-01 | Oxford Nanopore Tech Ltd | Methods and apparatus for forming apertures in a solid state membrane using dielectric breakdown |
| JP6719773B2 (ja) * | 2015-12-25 | 2020-07-08 | 国立大学法人大阪大学 | 分類分析方法、分類分析装置および分類分析用記憶媒体 |
| GB201707138D0 (en) * | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Machine learning analysis of nanopore measurements |
| CA3095030A1 (en) * | 2018-03-30 | 2019-10-03 | Juno Diagnostics, Inc. | Deep learning-based methods, devices, and systems for prenatal testing |
| GB201814369D0 (en) | 2018-09-04 | 2018-10-17 | Oxford Nanopore Tech Ltd | Method for determining a polymersequence |
-
2018
- 2018-11-28 GB GBGB1819378.9A patent/GB201819378D0/en not_active Ceased
-
2019
- 2019-11-26 SG SG11202103410TA patent/SG11202103410TA/en unknown
- 2019-11-26 BR BR112021008198-4A patent/BR112021008198A2/pt not_active Application Discontinuation
- 2019-11-26 CA CA3118632A patent/CA3118632A1/en active Pending
- 2019-11-26 CN CN201980076121.5A patent/CN113166804A/zh active Pending
- 2019-11-26 US US16/696,010 patent/US12264360B2/en active Active
- 2019-11-26 EP EP19816401.4A patent/EP3887543B1/en active Active
- 2019-11-26 AU AU2019389841A patent/AU2019389841B2/en active Active
- 2019-11-26 JP JP2021525061A patent/JP2022509589A/ja active Pending
- 2019-11-26 WO PCT/GB2019/053334 patent/WO2020109773A1/en not_active Ceased
-
2023
- 2023-06-29 JP JP2023106581A patent/JP2023126856A/ja active Pending
-
2025
- 2025-02-19 US US19/057,377 patent/US20250197929A1/en active Pending
- 2025-08-22 JP JP2025139101A patent/JP2025172079A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014531901A (ja) * | 2011-09-23 | 2014-12-04 | オックスフォード ナノポール テクノロジーズ リミテッド | ポリマー単位を含むポリマーの解析 |
| WO2015173587A1 (en) * | 2014-05-15 | 2015-11-19 | Oxford Nanopore Technologies Limited | Model adjustment during analysis of a polymer from nanopore measurements |
Non-Patent Citations (1)
| Title |
|---|
| BMC BIOINFORMATICS, vol. Vol.8(Suppl 7), S12, JPN6022026534, 2007, pages 1 - 16, ISSN: 0005001288 * |
Also Published As
| Publication number | Publication date |
|---|---|
| SG11202103410TA (en) | 2021-06-29 |
| JP2023126856A (ja) | 2023-09-12 |
| BR112021008198A2 (pt) | 2021-08-03 |
| CA3118632A1 (en) | 2020-06-04 |
| US20250197929A1 (en) | 2025-06-19 |
| AU2019389841A1 (en) | 2021-05-20 |
| JP2025172079A (ja) | 2025-11-20 |
| US12264360B2 (en) | 2025-04-01 |
| EP3887543B1 (en) | 2024-08-28 |
| EP3887543A1 (en) | 2021-10-06 |
| GB201819378D0 (en) | 2019-01-09 |
| AU2019389841B2 (en) | 2026-05-07 |
| US20200176082A1 (en) | 2020-06-04 |
| KR20210095641A (ko) | 2021-08-02 |
| WO2020109773A1 (en) | 2020-06-04 |
| CN113166804A (zh) | 2021-07-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3887543B1 (en) | Analysis of nanopore signal using a machine-learning technique | |
| US20250371230A1 (en) | Machine learning analysis of nanopore measurements | |
| US20250006308A1 (en) | Nanopore measurement signal analysis | |
| US20170096703A1 (en) | Analysis of a polymer from multi-dimensional measurements | |
| JP6226888B2 (ja) | ポリマーの測定の解析 | |
| KR102916805B1 (ko) | 중합체 서열을 결정하는 방법 | |
| EP3143538B1 (en) | Model adjustment during analysis of a polymer from nanopore measurements | |
| Azad et al. | Effects of choice of DNA sequence model structure on gene identification accuracy | |
| US7840358B2 (en) | Hierarchical statistical framework for separating mixed data | |
| Huang | Computational Methods Using Large-scale Population Whole-genome Sequencing Data |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20210510 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20220628 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20220920 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20221114 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20230228 |