JP2022508155A5 - - Google Patents
Info
- Publication number
- JP2022508155A5 JP2022508155A5 JP2021528339A JP2021528339A JP2022508155A5 JP 2022508155 A5 JP2022508155 A5 JP 2022508155A5 JP 2021528339 A JP2021528339 A JP 2021528339A JP 2021528339 A JP2021528339 A JP 2021528339A JP 2022508155 A5 JP2022508155 A5 JP 2022508155A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- composition according
- inhibitor
- agent
- melanoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862770446P | 2018-11-21 | 2018-11-21 | |
| US62/770,446 | 2018-11-21 | ||
| US201962798238P | 2019-01-29 | 2019-01-29 | |
| US62/798,238 | 2019-01-29 | ||
| US201962858036P | 2019-06-06 | 2019-06-06 | |
| US62/858,036 | 2019-06-06 | ||
| PCT/US2019/062525 WO2020106915A1 (en) | 2018-11-21 | 2019-11-21 | Methods of treating cancers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022508155A JP2022508155A (ja) | 2022-01-19 |
| JP2022508155A5 true JP2022508155A5 (https=) | 2022-11-29 |
Family
ID=70774067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021528339A Pending JP2022508155A (ja) | 2018-11-21 | 2019-11-21 | がんを治療する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20220016083A1 (https=) |
| EP (1) | EP3883580A4 (https=) |
| JP (1) | JP2022508155A (https=) |
| CN (1) | CN113573734A (https=) |
| WO (1) | WO2020106915A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017087885A1 (en) | 2015-11-19 | 2017-05-26 | Dana-Farber Cancer Institute, Inc. | Methods of identifying compounds that interfere with erg-driven misguidance of baf complexes in tmprss2-erg driven prostate cancers |
| US11497752B2 (en) | 2018-01-30 | 2022-11-15 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| WO2020081588A1 (en) | 2018-10-17 | 2020-04-23 | Dana-Farber Cancer Institute, Inc. | Swi/snf family chromatin remodeling complexes and uses thereof |
| EP3917517A4 (en) | 2019-01-29 | 2023-01-25 | Foghorn Therapeutics Inc. | CONNECTIONS AND USES THEREOF |
| US12384776B2 (en) | 2019-01-29 | 2025-08-12 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| CN113645971B (zh) * | 2019-01-29 | 2024-10-18 | 福宏治疗公司 | 化合物及其用途 |
| US12509453B2 (en) | 2019-01-29 | 2025-12-30 | Foghorn Therapeutics Inc. | BRM/BRG1 inhibitors and uses thereof |
| CN115484948A (zh) * | 2020-01-29 | 2022-12-16 | 福宏治疗公司 | 化合物及其用途 |
| AU2021213811A1 (en) | 2020-01-29 | 2022-07-28 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| TW202146412A (zh) | 2020-03-05 | 2021-12-16 | 美商Ｃ４醫藥公司 | 用於標靶降解brd9之化合物 |
| US12383555B2 (en) | 2020-05-20 | 2025-08-12 | Foghorn Therapeutics Inc. | Methods of treating cancers |
| AU2021293943A1 (en) * | 2020-06-18 | 2023-02-23 | Epizyme, Inc. | SMARCA4 inhibition for the treatment of cancer |
| KR20230128471A (ko) * | 2020-12-04 | 2023-09-05 | 에우불루스 바이오테라퓨틱스 인코포레이티드 | 헤테로아릴-아세틸렌, 이의 약제학적 조성물, 및 이의치료적 적용 |
| US12606553B2 (en) | 2021-03-09 | 2026-04-21 | Foghorn Therapeutics Inc. | Crystalline forms, compositions containing same, and methods of their use |
| US20240374605A1 (en) * | 2021-07-29 | 2024-11-14 | Foghorn Therapeutics Inc. | Methods of treating cancer |
| US20230265432A1 (en) * | 2021-10-21 | 2023-08-24 | Sanford Burnham Prebys Medical Discovery Institute | Methods and compositions for treating acute myeloid leukemia |
| WO2023234954A1 (en) * | 2022-06-03 | 2023-12-07 | Immunocore Limited | Methods of treating melanoma using tebentafusp and immune checkpoint inhibitors |
| EP4587126A1 (en) | 2022-09-13 | 2025-07-23 | Amphista Therapeutics Ltd | Compounds for targeted protein degradation |
| WO2024086577A1 (en) * | 2022-10-17 | 2024-04-25 | Foghorn Therapeutics Inc. | Methods of reducing or preventing metastases |
| WO2026052822A1 (en) | 2024-09-06 | 2026-03-12 | Amphista Therapeutics Limited | Tetrahydroisoquinoline compounds for targeted protein degradation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014150751A2 (en) * | 2013-03-15 | 2014-09-25 | Novartis Ag | Biomarkers associated with brm inhibition |
| JPWO2015005473A1 (ja) * | 2013-07-12 | 2017-03-02 | 国立研究開発法人国立がん研究センター | がんの治療への応答性を予測する方法 |
| US9694084B2 (en) * | 2014-12-23 | 2017-07-04 | Dana-Farber Cancer Institute, Inc. | Methods to induce targeted protein degradation through bifunctional molecules |
| MA41598A (fr) * | 2015-02-25 | 2018-01-02 | Constellation Pharmaceuticals Inc | Composés thérapeutiques de pyridazine et leurs utilisations |
| WO2017024318A1 (en) * | 2015-08-06 | 2017-02-09 | Dana-Farber Cancer Institute, Inc. | Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses |
| AU2018219292B2 (en) * | 2017-02-08 | 2024-09-26 | Dana-Farber Cancer Institute, Inc. | Tunable endogenous protein degradation with heterobifunctional compounds |
| CN110366418A (zh) * | 2017-02-28 | 2019-10-22 | 埃皮兹姆公司 | 抑制smarca2用于治疗癌症 |
-
2019
- 2019-11-21 JP JP2021528339A patent/JP2022508155A/ja active Pending
- 2019-11-21 EP EP19887386.1A patent/EP3883580A4/en not_active Withdrawn
- 2019-11-21 WO PCT/US2019/062525 patent/WO2020106915A1/en not_active Ceased
- 2019-11-21 CN CN201980089704.1A patent/CN113573734A/zh active Pending
- 2019-11-21 US US17/295,327 patent/US20220016083A1/en not_active Abandoned
-
2025
- 2025-02-19 US US19/057,594 patent/US20250235432A1/en active Pending
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