JP2022508155A5 - - Google Patents

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Publication number
JP2022508155A5
JP2022508155A5 JP2021528339A JP2021528339A JP2022508155A5 JP 2022508155 A5 JP2022508155 A5 JP 2022508155A5 JP 2021528339 A JP2021528339 A JP 2021528339A JP 2021528339 A JP2021528339 A JP 2021528339A JP 2022508155 A5 JP2022508155 A5 JP 2022508155A5
Authority
JP
Japan
Prior art keywords
cancer
composition according
inhibitor
agent
melanoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021528339A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022508155A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/062525 external-priority patent/WO2020106915A1/en
Publication of JP2022508155A publication Critical patent/JP2022508155A/ja
Publication of JP2022508155A5 publication Critical patent/JP2022508155A5/ja
Pending legal-status Critical Current

Links

JP2021528339A 2018-11-21 2019-11-21 がんを治療する方法 Pending JP2022508155A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862770446P 2018-11-21 2018-11-21
US62/770,446 2018-11-21
US201962798238P 2019-01-29 2019-01-29
US62/798,238 2019-01-29
US201962858036P 2019-06-06 2019-06-06
US62/858,036 2019-06-06
PCT/US2019/062525 WO2020106915A1 (en) 2018-11-21 2019-11-21 Methods of treating cancers

Publications (2)

Publication Number Publication Date
JP2022508155A JP2022508155A (ja) 2022-01-19
JP2022508155A5 true JP2022508155A5 (enExample) 2022-11-29

Family

ID=70774067

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021528339A Pending JP2022508155A (ja) 2018-11-21 2019-11-21 がんを治療する方法

Country Status (5)

Country Link
US (2) US20220016083A1 (enExample)
EP (1) EP3883580A4 (enExample)
JP (1) JP2022508155A (enExample)
CN (1) CN113573734A (enExample)
WO (1) WO2020106915A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12282014B2 (en) 2015-11-19 2025-04-22 Dana-Farber Cancer Institute, Inc. Methods of identifying compounds that interfere with ERG-driven misguidance of BAF complexes in TMPRSS2-ERG driven prostate cancers
EP3746124A4 (en) 2018-01-30 2021-10-27 Foghorn Therapeutics Inc. COMPOUNDS AND THEIR USES
US12473334B2 (en) 2018-10-17 2025-11-18 Dana-Farber Cancer Institute, Inc. SWI/SNF family chromatin remodeling complexes and uses thereof
AU2020214308A1 (en) * 2019-01-29 2021-08-12 Foghorn Therapeutics Inc. Compounds and uses thereof
US12384776B2 (en) 2019-01-29 2025-08-12 Foghorn Therapeutics Inc. Compounds and uses thereof
US12509453B2 (en) 2019-01-29 2025-12-30 Foghorn Therapeutics Inc. BRM/BRG1 inhibitors and uses thereof
EP3917517A4 (en) 2019-01-29 2023-01-25 Foghorn Therapeutics Inc. CONNECTIONS AND USES THEREOF
BR112022015109A2 (pt) * 2020-01-29 2022-11-08 Foghorn Therapeutics Inc Compostos e usos dos mesmos
WO2021155264A1 (en) 2020-01-29 2021-08-05 Foghorn Therapeutics Inc. Compounds and uses thereof
WO2021155262A1 (en) * 2020-01-29 2021-08-05 Foghorn Therapeutics Inc. Compounds and uses thereof
CN119823124A (zh) 2020-03-05 2025-04-15 C4医药公司 用于brd9的靶向降解的化合物
US12383555B2 (en) 2020-05-20 2025-08-12 Foghorn Therapeutics Inc. Methods of treating cancers
US20230295735A1 (en) * 2020-06-18 2023-09-21 Epizyme, Inc. Smarca4 inhibition for the treatment of cancer
KR20230128471A (ko) * 2020-12-04 2023-09-05 에우불루스 바이오테라퓨틱스 인코포레이티드 헤테로아릴-아세틸렌, 이의 약제학적 조성물, 및 이의치료적 적용
US12606553B2 (en) 2021-03-09 2026-04-21 Foghorn Therapeutics Inc. Crystalline forms, compositions containing same, and methods of their use
US20240374605A1 (en) * 2021-07-29 2024-11-14 Foghorn Therapeutics Inc. Methods of treating cancer
US20230265432A1 (en) * 2021-10-21 2023-08-24 Sanford Burnham Prebys Medical Discovery Institute Methods and compositions for treating acute myeloid leukemia
WO2023234954A1 (en) * 2022-06-03 2023-12-07 Immunocore Limited Methods of treating melanoma using tebentafusp and immune checkpoint inhibitors
AU2023343029A1 (en) 2022-09-13 2025-03-27 Amphista Therapeutics Limited Compounds for targeted protein degradation
WO2024086577A1 (en) * 2022-10-17 2024-04-25 Foghorn Therapeutics Inc. Methods of reducing or preventing metastases
WO2026052822A1 (en) 2024-09-06 2026-03-12 Amphista Therapeutics Limited Tetrahydroisoquinoline compounds for targeted protein degradation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2900301T3 (es) * 2013-03-15 2022-03-16 Novartis Ag Biomarcadores asociados con la inhibición de BRM
US20160130663A1 (en) * 2013-07-12 2016-05-12 National Cancer Center Method for predicting response to cancer treatment
US9694084B2 (en) * 2014-12-23 2017-07-04 Dana-Farber Cancer Institute, Inc. Methods to induce targeted protein degradation through bifunctional molecules
MA41598A (fr) * 2015-02-25 2018-01-02 Constellation Pharmaceuticals Inc Composés thérapeutiques de pyridazine et leurs utilisations
CA2994969A1 (en) * 2015-08-06 2017-02-09 Dana-Farber Cancer Institute, Inc. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses
US12023385B2 (en) * 2017-02-08 2024-07-02 Dana-Farber Cancer Institute, Inc. Tunable endogenous protein degradation with heterobifunctional compounds
KR20190140438A (ko) * 2017-02-28 2019-12-19 에피자임, 인코포레이티드 암 치료를 위한 smarca2의 저해

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